ライフサイエンスコーパス: fungal

1 d was higher in those with bacterial (8.2%), fungal (8.2%), or arboviral (8.9%) disease.

2 Both bacterial and fungal abundance and diversity decreased following sedim

3 ils and ILC2 responses after exposure to the fungal allergen Alternaria alternata Thus, CysLT1R promo

4 ce during type 2 inflammation induced by the fungal allergen Alternaria alternata.

5 Intravenous injection of IL-33 or pulmonary fungal allergen challenge mobilized ILC2 progenitors to

6 As shown here, eosinophils from fungal allergen-challenged wild-type mice maintain a dis

7 x vivo eosinophil cultures from the lungs of fungal allergen-challenged wild-type mice.

8 sulted in reinstatement of susceptibility to fungal allergen-induced allergic airways disease.

9 Furthermore, fungal allergy has been shown to play an important role

10 amphibian skin bacteria inhibit growth of a fungal amphibian pathogen, Batrachochytrium dendrobatidi

11 pendent comparative phylogenomic analyses of fungal and bacterial genomes are consistent with an anci

12 This condition is characterized by fungal and bacterial infections caused by impaired gener

13 yle of Xoc, and the importance of GA to both fungal and bacterial pathogens of rice.

14 Mining fungal and plant genomes along with evolutionary and gen

15 zoxaboroles are effective against bacterial, fungal and protozoan pathogens.

16 Bacterial, fungal, and plant metabolites are promising sources of s

17 n and transfer of the (13) C label to plant, fungal, and soil microbial tissue was examined in biomas

18 d lethal infections stemming from bacterial, fungal, and viral origins.

19 enteric windows and HMC-1 cells responded to fungal antigens by release of histamine.

20 at is expressed in plant cells accommodating fungal arbuscules.

21 andida) presence, nitrogen availability, and fungal assembly history.

22 intimately link the downstream responses to fungal attack and salt stress.

23 more susceptible than females to parasitic, fungal, bacterial, and viral infections.

24 gal effector functions in response to either fungal beta-glucan or C. albicans hyphae and fibronectin

25 eutrophils are exposed either to immobilized fungal beta-glucan or to C. albicans hyphae without ECM.

26 fluids and effectively inhibit formation of fungal biofilm.

27 n in biofilms, the influence of S. mutans on fungal biology in this mixed-species relationship remain

28 ke by fungi increases without an increase in fungal biomass or shift in bacterial-to-fungal ratio.

29 ), which resulted in prolonged elevations in fungal burden and histopathologic evidence of chronic lu

30 us-infected neutropenic lung correlated with fungal burden and hyphal length but not induction of GT

31 The patients with an ID consult had a higher fungal burden but a lower 90-day mortality compared to p

32 We harvested lungs for assessment of fungal burden, histology and GT/bmGT biosynthetic genes'

33 T cell-restricted Notch signaling increased fungal burdens in the lungs and CNS, diminished pulmonar

34 ification processes, but lower abundances of fungal C decomposition and anaerobic-related genes.

35 fractionation is thus due to differences in fungal cell mass fluxes.

36 nic activity of WGA-Fc effectively modulates fungal cell recognition and promotes the elimination of

37 es, suggesting that utilization of yeast and fungal cell wall 1,6-beta-glucans is a widespread adapta

38 tion of a plant polysaccharide but targets a fungal cell wall glycan, 1,6-beta-glucan, which is a gro

39 olysaccharide-rich wall, which envelopes the fungal cell, is pivotal to the maintenance of cellular i

40 microscopy (CLSM) showed that the number of fungal cells attached to the modified PMMA resin was con

41 Fungal cells colonize and proliferate in distinct niches

42 Additionally, fungal cells invaded host muscle fibers and joined toget

43 Fungal cells were found throughout the host body but not

44 ases release of capsular polysaccharide from fungal cells.

45 of the 14alpha-demethylase enzyme present in fungal cells.

46 These findings suggest that the fungal cellulosome is an evolutionarily chimaeric struct

47 ever, the biocatalytic activity of anaerobic fungal cellulosomes is expanded by the inclusion of GH3,

48 food samples, based on the identification of fungal chemical markers by HPLC-MS, was developed.

49 composition has been confirmed in plants and fungal cis-PTs.

50 mine whether anti-PD-1 Ab treatment improves fungal clearance.

51 at control the plant processes necessary for fungal colonisation and arbuscule development.

52 s irregularis, root developmental responses, fungal colonization and transcriptional responses were m

53 Our results indicate that plant-associated fungal communities are more strongly influenced by host

54 antify the responses of ectomycorrhizal (EM) fungal communities associated with poorly performing hos

55 stic and stochastic processes structure soil fungal communities following landscape-scale insect outb

56 in natural environments: both bacterial and fungal communities in urban parks responded to plant fun

57 ation, management strategies that bolster AM fungal communities may in turn create systems that are m

58 ges in ecosystem respiration, plant and soil fungal communities occurred when the water level fell be

59 pacer 2, we studied the root and rhizosphere fungal communities of A. alpina growing under natural an

60 ed fecal-associated bacterial, archaeal, and fungal communities of dairy cows from 2 weeks to the mid

61 We observed that the fungal communities of mycoheterotrophic and green plants

62 Seed-associated fungal communities strongly differed across strains, but

63 EM fungal communities were assessed with high-throughput se

64 on did affect the composition of rhizosphere fungal communities.

65 hizosphere and root endosphere bacterial and fungal communities.

66 drought had a legacy effect on bacterial and fungal community composition that decreased plant growth

67 ass and significantly distinct bacterial and fungal community compositions depending on the substrate

68 ing the link between host performance and EM fungal community structure will to clarify how climate c

69 ignment tools classify unique members of the fungal community, and greater classification power is re

70 eral sources in the soil, besides increasing fungal competition for progressively limited resources.

71 chimaeric structure-an independently evolved fungal complex that co-opted useful activities from bact

72 genomics, we identify new genes involved in fungal complexification.

73 Diminished fungal containment in MARCO(-/-) mice was accompanied by

74 Fungal contamination and infection from donor tissues pr

75 240 patients with smear-positive filamentous fungal corneal ulcers who enrolled between May 2010 and

76 F may be better estimated by using selective fungal culture media, and this may translate to importan

77 Fungal culture or histopathology confirmed Cryptococcus

78 ary outcome measures were positive donor rim fungal culture results and the development of postkerato

79 sults (n = 117), and specimens with negative fungal culture, but with microscopic and ancillary findi

80 e specimens for detecting fungi; microscopy, fungal culture, galactomannan antigen, and aspergillus P

81 enty-one cases (2.1%) were associated with a fungal culture-positive donor rim.

82 etermine the incidence of positive donor rim fungal cultures and clinical outcomes of all grafts usin

83 Despite the importance of ions in fungal decay mechanisms, the spatial distribution and qu

84 The role of ions in the fungal decay process of lignocellulose biomaterials, and

85 ostharvest life and are prone to postharvest fungal decay.

86 n the regulation of endosome dynamics during fungal development and plant infection.

87 n to define patients with high-risk invasive fungal disease (IFD), changes in recommended biomarkers

88 Snake fungal disease (SFD) is an emerging disease of conservat

89 pment of clinically relevant mouse models of fungal disease and the discovery and characterization of

90 Fungal disease diagnosis requires a high level of clinic

91 al medicines; and concomitant integration of fungal disease into training of the health workforce.

92 tritici, is a major fungal disease of wheat worldwide.

93 le oil characteristics and resistance to the fungal disease Verticillium wilt are top priorities for

94 education and training in the management of fungal disease, have the potential to improve patient ou

95 lungs of individuals with well-characterized fungal disease.

96 ng approach including greater integration of fungal diseases into existing HIV infection, tuberculosi

97 on of enhanced laboratory capacity to detect fungal diseases with associated surveillance systems; pr

98 ata show that combined monitoring for GM and fungal DNA also results in a high diagnostic accuracy in

99 se interaction motifs provide hypotheses for fungal-driven dynamics behind observed plant invasion tr

100 equence identity in its N-terminal half with fungal DSDs.

101 induced by growth inhibitors, in contrast to fungal dsRNA viruses.

102 ume extracts was enhanced by germination and fungal elicitation of seven legume species, as establish

103 edulis) and its mutualistic ectomycorrhizal fungal (EMF) associates, we show that EMF community comp

104 (IVDA) is a known risk factor for endogenous fungal endophthalmitis (EFE), a severe intraocular infec

105 There were no cases of fungal endophthalmitis.

106 Similarly, F. graminearum affected fungal endophytes including Trichoderma and Endogone.

107 acterisation of activity of CAZymes, such as fungal enzymes for plant lignocellulose degradation with

108 ighest sequence similarity with archaeal and fungal enzymes, which peak in two redox transition zones

109 We hypothesize that changes to the fungal ER represent a conserved process in specialized e

110 rolysis of eight aliphatic polyesters by two fungal esterases (FsC and Rhizopus oryzae lipase) at dif

111 ental asthma models to explore the effect of fungal exposure on asthma development and severity.

112 Similarly, in children with asthma, fungal exposure was associated with increased serum IL-1

113 A/IL-22 axis via IL-33 signaling during lung fungal exposure.

114 Increasing evidence implicates high indoor fungal exposures as a precipitant of asthma in children

115 e mechanisms that protect against ubiquitous fungal exposures.

116 filing we demonstrate that (13)C patterns of fungal FAs recapitulate those of wild-type hosts, indica

117 average sensitivity of LS-IVCM for detecting fungal filaments was 71.4% +/- 0% for the experienced ob

118 hydrate antigen expression between these two fungal forms.

119 Graminoids indirectly influenced fungal functional composition and soil enzyme activities

120 dence that such molecules can also influence fungal-fungal interactions.

121 Bioinformatic analysis showed that fungal Fzo1 proteins exhibit two predicted transmembrane

122 cilitated identification of highly expressed fungal genes.

123 enzymes for polysaccharide deconstruction in fungal genomes and will help identify new strains and en

124 onses were examined during spore attachment, fungal germination and pre-penetration of the cuticle, a

125 However, the pathogenic mechanisms of fungal GH12 proteins have not been characterized.

126 ese infections lack the draining sinuses and fungal grains characteristic of eumycetoma.

127 B. cinerea showed a significant decrease in fungal growth after 7days at 5 degrees C.

128 Fungal growth was inhibited on the AgBr/NPVP-modified PM

129 ), 430 (7.5%) were positive for bacterial or fungal growth, with 342 (6.0%) clinically significant an

130 es and provide insight into the mechanism of fungal halogenases.

131 dobacterium likely extracted malate from the fungal host as the primary carbon substrate for energy p

132 ctivity during cell wall differentiation and fungal hydrophobin function.

133 on of ions in lignocellulosic cell walls and fungal hyphae during decay is not known.

134 from mm to submicron length scales in wood, fungal hyphae with the dried extracellular matrix (ECM)

135 ith substantially different affinity towards fungal hyphae.

136 in vitro substrate specificity with those of fungal Icp55 enzymes.

137 Traditional methods for fungal identification are based on morphological charact

138 To assess how fungal immunological biomarkers are related to fixed air

139 -33 administration to normal mice attenuated fungal-induced IL-17A and IL-22, but not IL-1alpha, IL-1

140 ether this pathway contributes to persistent fungal infection and to determine whether anti-PD-1 Ab t

141 Fungal infection is highly associated with ESCCs in non-

142 e mortality and may have decreased secondary fungal infection rates.

143 orescences of maize under local and systemic fungal infection treatments, respectively.

144 ults and the development of postkeratoplasty fungal infection using corresponding corneal tissue.

145 ral tolerance, autoreactive T cells, chronic fungal infection, and ESCCs expressing specific human ES

146 ted outcome of CLR ligation in bacterial and fungal infection.

147 xity regulating the fly response to systemic fungal infection.

148 the host cuticle during the early stages of fungal infection.

149 ssion in wood compared to bark tissues after fungal infection.

150 bute to the de novo biosynthesis of JA after fungal infection.

151 NK1 may be a therapeutic target for treating fungal infection.

152 Six patients (5%) developed invasive fungal infections and 5 patients (4%) had life-threateni

153 by recurrent life-threatening bacterial and fungal infections and aberrant inflammation.

154 0.14) but significantly decreased secondary fungal infections by 50% (risk ratio, 0.49; 95% CI, 0.35

155 ection breaks down, superficial and invasive fungal infections cause diseases that range from irritat

156 Invasive fungal infections cause significant morbidity and mortal

157 g is associated with lower rates of invasive fungal infections compared with placebo or no interventi

158 ic, and therapeutic interventions, resistant fungal infections continue to cause significant morbidit

159 Opportunistic fungal infections continue to take an unacceptably heavy

160 The incidence of systemic fungal infections has decreased in people with HIV in hi

161 IVCM sensitivity was higher in patients with fungal infections who had positive culture or longer dur

162 elucidate the role of Notch signaling during fungal infections, we infected mice expressing the pan-N

163 s available to treat drug-resistant invasive fungal infections.

164 s in the diagnosis and treatment of invasive fungal infections.

165 urses were not consistent with true invasive fungal infections.

166 isms that may influence the plant-associated fungal interaction networks.

167 er may be driven by specificity in the plant-fungal interaction, the size of the effect of the symbio

168 dence (obligate to facultative) of the plant-fungal interaction.

169 In some situations, the effects of plant-fungal interactions are inconsistent or negligible.

170 Using amplicon sequencing of the fungal internal transcribed spacer 2, we studied the roo

171 or elucidating host mechanisms that regulate fungal intracellular parasitism.

172 be clinically effective against a particular fungal isolate.

173 A panel of 140 clinical fungal isolates was used in both PCR and real-time PCR a

174 Here we show that fungal iterative NRPSs adopt an alternate incorporation

175 the way for the transition from traditional fungal karyotyping to more comprehensive chromosome biol

176 study included 21 patients with filamentous fungal keratitis and 24 patients with bacterial keratiti

177 Fungal keratitis developed in 4 cases (5.6%), and all pa

178 nosinusitis, postoperative aspergillosis and fungal keratitis.

179 However, some fungal kinesin-5 motors are bidirectional.

180 es in the composition of the wall across the fungal kingdom, addresses how little is known about the

181 zation correlates with host range across the fungal kingdom.

182 l of a hemolymph-specific promoter increased fungal lethality to mosquitoes at spore dosages as low a

183 vast majority of these molecules during the fungal life cycle in nature remain elusive.

184 Oomycetes are fungal-like eukaryotic microbes in the kingdom Stramenop

185 criptionally active genes in early-diverging fungal lineages.

186 No study has yet examined the mycobiome in fungal lung disease.

187 lecular mechanism for binding of dectin-2 to fungal mannans and also to bacterial lipopolysaccharides

188 piperazine-azole hybrids do not function by fungal membrane disruption, but instead by disruption of

189 It has long been hypothesized the fungal metabolism plays a critical role in virulence tho

190 ignocellulose biomaterials, and more broadly fungal metabolism, has implications for diverse research

191 the identified compounds correspond to a new fungal metabolite (29) and a new actinobacterial angucyc

192 Ochratoxin A (OTA) is a fungal metabolite and putative carcinogen which can cont

193 oquinone (2,6-DMHQ), an analogue to a common fungal metabolite, and its reaction with ferrihydrite an

194 , in which plants pre-treated with chitin (a fungal microbe-associated molecular pattern) have improv

195 Our knowledge of the fungal microbiome (mycobiome) is limited to a few studie

196 interactions, we studied the root-associated fungal microbiome of Arabis alpina (Brassicaceae) with t

197 A canonical fungal mitochondrial genome was recovered from P. saccam

198 In addition, RNAi research on new fungal models has uncovered the role of small RNAs and R

199 articularly difficult for samples containing fungal mycelia, where processing removes morphological c

200 Here, we report that the fungal nitrooxidative stress response suppresses host de

201 Product template (PT) domains from fungal nonreducing polyketide synthases (NR-PKSs) are re

202 ta (from the past decade) pertaining towards fungal occurrence and level of mycotoxins in various oil

203 Safety concerns pertaining towards fungal occurrence and mycotoxins contamination in agri-f

204 The highest fungal occurrence was in Barhi (30%) followed by Sukari

205 The TPC had a negative correlation with fungal occurrence whilst the total sugars had a positive

206 Here we compare how three common fungal OTU taxonomic assignment tools (RDP Classifier, U

207 el interactions between the species-specific fungal parasite Ophiocordyceps unilateralis sensu lato a

208 As a result, scientific interest towards fungal parasites of phytoplankton has been gaining momen

209 ons, as well as co-evolutionary feedbacks of fungal parasitism on host populations is also limited.

210 cient to impair NADPH oxidase recruitment to fungal particles that are normally cleared by LAP.

211 d- and warm-adapted amphibian species to the fungal pathogen Batrachochytrium dendrobatidis (Bd) usin

212 bian species suffering extirpations from the fungal pathogen Batrachochytrium dendrobatidis (Bd), we

213 ous factors, including pesticide use and the fungal pathogen Batrachochytrium dendrobatidis (Bd).

214 Here we define circuitry that enables the fungal pathogen Candida albicans to couple cell cycle dy

215 ucture of the kinase domain of Trl1 from the fungal pathogen Candida albicans with GDP and Mg2+ in th

216 eutrophils, is required for clearance of the fungal pathogen Candida albicans.

217 istone deacetylase inhibitor produced by the fungal pathogen Cochliobolus carbonum race 1, promotes v

218 The fungal pathogen Histoplasma capsulatum minimizes detecti

219 ntry rates by Colletotrichum higginsianum, a fungal pathogen showing direct penetration of leaf epide

220 agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annu

221 mato variety resistant to the powdery mildew fungal pathogen using the CRISPR/Cas9 technology.

222 nilensis to infection by the locust-specific fungal pathogen, Metarhizium acridum.

223 Aspergillus fumigatus, a ubiquitous human fungal pathogen, produces asexual spores (conidia), whic

224 ization in a generalist but not a specialist fungal pathogen.

225 SEP4-mediated fungal pathogenic development, including IFS formation,

226 bility of low-temperature of cold tolerance, fungal pathogenicity and specialized host infection.

227 front-line defense of numerous bacterial and fungal pathogens against H2O2-induced oxidative damage f

228 IFI outbreaks are caused by many different fungal pathogens and are associated with numerous settin

229 olerance to abiotic stressors, resistance to fungal pathogens and grain quality.

230 elocation, occupation, or immunosuppression; fungal pathogens appearing in geographical areas in whic

231 honuclear neutrophils (PMN) to bacterial and fungal pathogens as well as to model inflammatory stimul

232 dentified that protein effectors secreted by fungal pathogens can spread between host cells via PD.

233 nhibitory activity against the opportunistic fungal pathogens Candida albicans and Cryptococcus neofo

234 The fungal pathogens Candida albicans, Cryptococcus neoforma

235 d with defense responses against insects and fungal pathogens in Pinus species, increasing current kn

236 Fungal pathogens represent a significant threat to immun

237 henotypes on their hosts (protection against fungal pathogens vs. parasitoid wasps) and symbionts wit

238 major target of clinical drugs for managing fungal pathogens, but some of the CYP51 key features imp

239 using BODIPY-cPAF26 for wash-free imaging of fungal pathogens, including real-time visualization of A

240 creased susceptibility to both bacterial and fungal pathogens, whereas plants with reduced TOR signal

241 Fungal pathogens, which can occupy distinct host tissues

242 recognition and promotes the elimination of fungal pathogens.

243 died, although it is key in the clearance of fungal pathogens.

244 n as a live-cell imaging probe for different fungal pathogens.

245 tifungal agent with activity against diverse fungal pathogens.

246 l of P. xylostella to limit the infection of fungal peptide destruxin A by increasing the activity of

247 Fungal peritonitis in a patient on peritoneal dialysis (

248 sable elements (MULEs) are widespread across fungal, plant and animal species.

249 thod for thin lung tissue sections in murine fungal pneumonia achieved sensitivity/specificity 0.99/0

250 clathrin-independent function necessary for fungal polar growth.

251 uencing is increasingly used to decipher the fungal populations present in complex samples such as mu

252 modest but significant effects on plant and fungal productivity and nutrient retention, but no effec

253 m multifunctionality by regulating plant and fungal productivity, soil CO2 efflux and nutrient retent

254 biont gaining transcriptional control of the fungal ras2 gene, which encodes a GTPase central to fung

255 e in fungal biomass or shift in bacterial-to-fungal ratio.

256 ras2 gene, which encodes a GTPase central to fungal reproductive development.

257 ffect of DW on contribution of bacterial and fungal residues to N transformation was also related to

258 variability of N2O fluxes, driven in part by fungal respiration and/or iron redox cycling.

259 arcodes were generated for 33 representative fungal samples, all of which could be used by consumers

260 es to communities assembled by attraction to fungal scent.

261 Fungal secondary metabolites (SMs) are extremely importa

262 l specific gene expression for nine putative fungal secreted proteins.

263 lmonary aspergillosis and severe asthma with fungal sensitization.

264 RDP Classifier, UTAX, and SINTAX) handle ITS fungal sequence data.

265 ergillus nidulans for negative regulators of fungal SM gene clusters and we have used this screen to

266 ny aspects of biological differences between fungal species cannot be explained by current knowledge

267 interactive effects of all three factors on fungal species composition and wood decomposition 1 year

268 the characterization of mycotoxin-producing fungal species from the genera Aspergillus and Fusarium

269 Here they demonstrate that most fungal species have ArsM orthologs with only three conse

270 ed secondary metabolites produced by diverse fungal species including the plant pathogen Ascochyta ra

271 Two fungal species showed formation of a mantle and one show

272 What and how pigments function in a fungal species with multiple cell conidia is poorly unde

273 ompared the interaction of conidia from both fungal species with MUTZ-3-derived dendritic cells (DCs)

274 ational analyses of orthologous RNAs from 62 fungal species.

275 se functions and essentiality differ between fungal species.

276 anscribed spacer (ITS) of the rRNA gene with fungal specific ITS primers, ITS barcodes were generated

277 The Dig1 negative regulators are part of a fungal-specific module that includes a transcription fac

278 id) in oil-in-water emulsions to control the fungal spoilage of strawberry jams, minimising essential

279 risk to global wheat production, because the fungal spores transmitting the disease can be wind-dispe

280 d broad-spectrum activity against all tested fungal strains, with excellent minimum inhibitory concen

281 genation of malbrancheamide in two different fungal strains.

282 as revealed in the case of 6 bacterial and 2 fungal strains.

283 exchange takes place through highly branched fungal structures called arbuscules that are formed in c

284 However, fungal surveillance is not routinely performed in most c

285 eriments of this nature have been limited to fungal systems due to lack of mammalian genome-wide dele

286 to regulate translation elongation speed in fungal systems, but its effect on translation elongation

287 development, and deployment of host- and/or fungal-targeted therapeutics.

288 We observed the enrichment of bacterial and fungal taxa commonly found in drinking water distributio

289 uding low-P soils and identified a set of 15 fungal taxa consistently detected in its roots.

290 We identified a broad distribution of fungal taxa predominated by Chytridiomycota and Dikarya.

291 is of the 18S rRNA sequences, we showed that fungal taxa represented between 0.93% and 60.32% of the

292 s more pronounced, and also involved several fungal taxa.

293 The most dominant EM fungal taxon detected in the homogeneous treatment was a

294 question using the network controlled by the fungal transcription regulator Ndt80.

295 Fungal tRNA ligase (Trl1) is an essential enzyme that re

296 Patients with culture-positive filamentous fungal ulcers and visual acuity of 20/40 to 20/400 reexa

297 ical natamycin over topical voriconazole for fungal ulcers, particularly among those caused by Fusari

298 icing and non-canonical mRNA splicing in the fungal unfolded protein response.

299 study group) and 50 patients with bacterial, fungal, viral, or immune keratitis featuring negative Ac

300 For the most-extreme fungal xerophiles, metabolic activity and cell division