ライフサイエンスコーパス: fungiform papillae

1 nique tongue lesion, which comprises swollen fungiform papillae.

2 relationship between nerve and taste buds in fungiform papillae.

3 tory axons to correctly locate and innervate fungiform papillae.

4 s play essential roles in the development of fungiform papillae.

5 ssion of BDNF and NT4 disrupt innervation to fungiform papillae.

6 before or during the initial innervation of fungiform papillae.

7 yte response to denervation of taste buds in fungiform papillae.

8 the tongue that matched the distribution of fungiform papillae.

9 ing from the foliate, vallate, and posterior fungiform papillae.

10 (Ca(2+)(I)) induced by acidic stimuli in rat fungiform papillae.

11 ns in BDNF-OE and NT4-OE mice innervated few fungiform papillae.

12 papillae > nasoincisor duct and epiglottis > fungiform papillae.

13 ngs from isolated taste cells showed that in fungiform papillae, aldosterone increased the number of

14 ation only in taste buds, whereas 43% of the fungiform papillae also had additional labeled innervati

15 Here, we report that Shh expression in fungiform papillae and formation of normal mature fungif

16 cell responses of 120 taste cells of the rat fungiform papillae and soft palate maintained within the

17 oth transgenic lines had severe reduction in fungiform papillae and taste bud number, primarily in th

18 Fungiform papillae and taste buds were reduced in number

19 gnaling has roles in forming and maintaining fungiform papillae and taste buds, most likely via stage

20 in causes massive overproduction of enlarged fungiform papillae and taste buds.

21 -/-) mice the abundance of axons innervating fungiform papillae and the normal numbers of geniculate

22 three subunits in nearly all taste cells of fungiform papillae, and in about half of the taste cells

23 gue, with high levels in taste bud placodes, fungiform papillae, and mature taste cells, and low leve

24 60, there was 63% decrease in the number of fungiform papillae, and remaining papillae were smaller

25 Fungiform papillae are epithelial specializations that d

26 Furthermore, on anterior tongue, the fungiform papillae are patterned in rows.

27 Fungiform papillae are repeated epithelial structures th

28 ustatory innervation and a reduced number of fungiform papillae at birth.

29 ithelial targets of gustatory neurons (i.e., fungiform papillae) before their innervation, and BDNF o

30 ate neurons approach their target cells, the fungiform papillae, beginning on E13.5, at which time we

31 cells from mouse circumvallate, foliate, and fungiform papillae but not in a variety of other cells,

32 bute not only to maintenance of filiform and fungiform papillae, but also to taste buds.

33 all taste buds disappeared in more posterior fungiform papillae by 15 days posttransection, the anter

34 -expressing cells per taste bud, whereas the fungiform papillae contained 3.06 and 0.23 cells per tas

35 form papillae and formation of normal mature fungiform papillae depend on signaling through Wnt and b

36 In addition, fungiform papillae developed on posterior oral tongue, j

37 Furthermore, fungiform papillae developed on these tongues on a cultu

38 that FGF signaling is a crucial regulator of fungiform papillae development.

39 which is the main activation pathway during fungiform papillae development; however, this effect doe

40 Fungiform papillae did not develop on pharyngeal or vent

41 Taste cells of fungiform papillae did not show immunoreactivity for pre

42 single circumvallate papilla, regions where fungiform papillae do not typically develop.

43 apillae was significantly lower than that of fungiform papillae, especially for beta and gamma subuni

44 were sustained, TB were not restored in all fungiform papillae even with prolonged recovery for seve

45 In addition, fungiform papillae formed in the tongue cultures in the

46 In the rat, taste buds of the fungiform papillae had fewer gustducin-positive cells (3

47 Most (57%) of the fungiform papillae had labeled innervation only in taste

48 initial formation and early morphogenesis of fungiform papillae in a patterned array.

49 nor does the tongue retain competency to add fungiform papillae in atypical locations.

50 The Shh protein was in all fungiform papillae in embryonic tongues, and tongue cult

51 erefore, robust, reproducible development of fungiform papillae in patterns is supported in rat tongu

52 ed tongue results in an increased density of fungiform papillae in the mutant tongues.

53 buds, and stratified squamous epithelium of fungiform papillae in the tongue, as well as in skeletal

54 s BMPs or noggin induce increased numbers of fungiform papillae, in a concentration-dependent manner,

55 al Wnt paths in regulating tongue growth and fungiform papillae is proposed in a model, through the R

56 Fungiform papillae must contain long-lived, sustaining o

57 w it encompasses additional phenotypes (e.g. fungiform papillae number, bitterness of quinine) and em

58 lso expressed in the nail bed epithelium and fungiform papillae of dorsal tongue epithelium.

59 curs in vibrissae follicles, in filiform and fungiform papillae of oral mucosa.

60 erally and appear to originate in the dorsal fungiform papillae of the tongue epithelium.

61 the cornified tips of the filiform (but not fungiform) papillae of the dorsal tongue and in the supe

62 an irreversibly alter number and location of fungiform papillae on anterior tongue and elicit papilla

63 petence of dorsal lingual epithelium to form fungiform papillae on both anterior and posterior oral t

64 rmates and made quantitative analyses of all fungiform papillae on the anterior tongue, the single ci

65 colocalized within papilla placodes and the fungiform papillae per se, have opposing inhibitory and

66 ut most of the additional innervation in the fungiform papillae remained.

67 uding reduced growth rate, reduced number of fungiform papillae, spinal abnormalities, and sensory an

68 s chorda tympani fibers to distinguish their fungiform papillae targets from non-gustatory epithelium

69 mice, in which taste neurons innervated only fungiform papillae, taste neurons in BDNF-OE and NT4-OE

70 In early fungiform papillae, tenascin immunoreactivity is very we

71 In all fungiform papillae that form under various culture condi

72 To explain the loss of nerve innervation to fungiform papillae, the facial nerve of developing anima

73 umbers of embryonic taste buds in developing fungiform papillae until birth are not correlated with t

74 In addition, the size and number of fungiform papillae were greatly reduced in Lef1 knockout

75 Fungiform papillae were initially present on tongues of

76 No degenerative deficits of fungiform papillae were observed for the first 3 weeks o

77 Remaining fungiform papillae were selectively concentrated in the

78 However, these remaining fungiform papillae were smaller in appearance and many d

79 In mice, individual taste buds reside in fungiform papillae, which develop at mid-gestation as ep