ライフサイエンスコーパス: fused ring

1 ith 16 fused rings (from a precursor with no fused rings).

2 k]tetraphene-derived oligomers with up to 13 fused rings.

3 our phenyl rings appended to the two central fused rings.

4 ne-like hydrocarbons with the same number of fused rings.

5 linearly extended conjugated core with eight fused rings.

6 mposed of alternating linearly and angularly fused rings.

7 s into a three-dimensional random network of fused rings.

8 fluoromethyl)mercury and sodium iodide] gave fused-ring 2,2-difluorocyclopropane compounds.

9 Promoter sterols have flat, fused rings, a hydroxyl headgroup, an alkyl tail, and a

10 dily from phenylalanine derivatives, but the fused-ring analogues 5 could not be obtained in good yie

11 key dihedral angle was constrained to design fused-ring analogues, substituted N-arylpyrrolopyridines

12 sessment of aromatic competition between the fused rings and the central borepin core.

13 sis of complex carbocycles composed of three fused rings and up to five stereocenters with complete s

14 ionalized chiral tetrahydrofurans as well as fused-ring and bridged-ring oxabicyclic products.

15 Fused-ring and bridged-ring tetrahydrofuran scaffolds ar

16 dditional flexibility not available when the fused rings are intact.

17 ted against spectra measured for a number of fused-ring aromatic hydrocarbon molecules containing var

18 Well-defined, fused-ring aromatic oligomers represent promising candid

19 These requirements may involve planar fused-ring aryl systems and possibly hydrogen-bonding ca

20 drocarbons (PAHs), ranging from two to seven fused rings, as a result of its large, accommodating cav

21 was found to be similar for chromenes with a fused ring at the 7,8-positions.

22 el anticancer agents, we explored the SAR of fused rings at the 7,8-positions.

23 on involving spontaneous ring expansion of a fused-ring benzazirine into a seven-membered ring cyclic

24 The synthesis of novel fused-ring bicyclic (4-6) and tricyclic (7-10) nicotine

25 ain three stereogenic centers and up to four fused rings can be accessed in two steps from relatively

26 From these results, it is clear that the fused ring carbazoles can bind strongly in the DNA minor

27 om three different structural classes: rigid fused ring compounds [dihydrexidine, dinapsoline, dinoxy

28 Among the bicyclic fused-ring congeners 17-38, the indole-containing analog

29 Previously undescribed [4.4.0] and [5.3.0] fused-ring-containing products were obtained when santon

30 ed in planar molecular geometry containing a fused-ring core.

31 3-gh][3,8]phenanthroline-5,11(4H,10H)-dio ne fused-ring derivatives.

32 report the synthesis of a novel ladder-type fused ring donor, dithienogermolodithiophene, in which t

33 -1H-inden-1-ylidene)malononitrile to yield a fused-ring electron acceptor (IOIC2) for organic solar c

34 Now a superior hydrogen-free 5/6/5 fused ring energetic material, 1,2,9,10-tetranitrodipyra

35 lar coupling to form a helical ZrPAH with 16 fused rings (from a precursor with no fused rings).

36 This pharmacophore comprises a 6 + 5 fused ring heterocycle linked to an aliphatic substituen

37 The fused-ring heterocycle is stabilized under acidic condit

38 Oligomers containing the new fused-ring heterocyclic conjugated building block thieno

39 Fused rings in Vegavis form a well-mineralized pessulus,

40 ed a preference for the formation of the cis-fused rings, in agreement with experimental results.

41 ring was less than 100-fold, suggesting that fused-ring intermediates were not formed.

42 tepwise loss in aromaticity as the number of fused rings is increased from one to two to three.

43 ize because of the highly strained 5,6-trans-fused ring junction that had to be formed.

44 yclic enones (7 and 10) that contain A/B-cis-fused ring junctions.

45 of this class is a scaffold of four linearly fused rings, labeled A through D.

46 ogical activities indicate that a variety of fused-ring minor-groove binding agents should be investi

47 from several classes of thia-PAHs with four fused rings, namely, benzo[b]naphtho[2,1-d]thiophene (1)

48 most effective analogues have tryptophan or fused-ring non-natural amino acids at position 4 and ala

49 The fused-ring non-natural amino acids at position 4 contrib

50 nce for activity and that a minimum of a two-fused-ring nucleobase is required for activity to exceed

51 Methyl substitution of the benzo-fused ring of 29 at the 7-, 8-, and 10-positions resulte

52 vage of the beta-lactam ring, when the rigid fused rings of benzylpenicillin and cephaloridine each f

53 withdrawing fluoro substituents on the benzo fused-ring of the isoselenazolone appear to enhance the

54 associated with furan ring substitution into fused-ring oligothiophenes on the electronic properties

55 A series of fused-ring oligothiophenes were synthesized by a combina

56 6-membered pyrido and the 5-membered pyrrolo fused rings on quinone methide and vinyl quinone formati

57 further insight into the biogenesis of such fused-ring polyether systems.

58 tions 4 and 5, and formation of a hexacyclic fused-ring product with N-phenyltriazolinedione.

59 iyn-1-als, affording the corresponding 5-7-5 fused-ring products bearing a seven-membered lactone moi

60 The size of the fused ring profoundly influences the temperature that is

61 carbon spacer results in the formation of a fused ring rather than the classic methide species.

62 Hexacene and larger fused rings remain elusive targets for chemists.

63 s (particularly for species with multiple or fused rings) remains uncertain.

64 opore volume, H/C ratio, O/C ratio, aromatic fused ring size, or HTT.

65 defines the conformation of the substrates' fused ring skeleton that ultimately distinguishes betwee

66 xacene-like molecule containing six linearly fused rings, specifically a pentacene molecule fused wit

67 revious report we showed that, despite their fused ring structure, the carbazoles also bind in A/T se

68 tural product architectures led to a complex fused ring system ideally suited to bind to the MDM2 pro

69 we show how spin density is affected by the fused ring system substituents.

70 reaction for the construction of the bridge-fused ring system was demonstrated.

71 The structure of the tetracyclic spiro-fused ring system was unambiguously confirmed by X-ray d

72 large part by the degree of planarity of the fused ring system whereas functional selectivity was dep

73 -allene [4+3] cycloaddition to build the 5,7-fused ring system with an oxa-bridge in one step, and a

74 on) and the stereoselectivity (trans- vs cis-fused ring system) of the cyclization process can be con

75 trated by efficient synthesis of a different fused ring system, represented by the antihelmintic praz

76 mediate, which, on hydrogenloysis, gives the fused ring system.

77 a rapid ring closure to the more stable cis-fused ring system.

78 ry or remote stereochemistry in this kind of fused ring system.

79 h 2 equiv of diphenylketene afforded a spiro-fused ring system: azoniabenzo[de]fluorine.

80 riation of the N-alkyl chain and of the aryl fused-ring system provides an accounting of bile salt mo

81 ndoloquinoline units incorporated in a seven-fused-ring system.

82 obal aromatic characters of various rings in fused ring systems built upon boron heterocycles.

83 ion mode, and this may be engineered to form fused ring systems by an initial exo-mode nucleophilic c

84 ntaining benzodiazepinone- and quinazolinone-fused ring systems can be assembled by nonribosomal pept

85 us to efficiently forge the intricate 5-8-5 fused ring systems found in numerous complex natural pro

86 nitration reaction sequence leading to trans-fused ring systems have been investigated with density f

87 anidine, and reversed amidine derivatives of fused ring systems have been synthesized from their corr

88 ms because they reflect the inability of the fused ring systems to respond to changes in aromaticity/

89 rpenes with unprecedented 6/11/5 and 6/6/7/5 fused ring systems when transiently co-expressed with a

90 arge methylene-bridged PAHs (mostly 22pi six-fused ring systems).

91 en studied ranging from single aryl rings to fused ring systems, and also styryl substituents, establ

92 noldiazo compounds that produce cyclopropane-fused ring systems.

93 function of extended conjugation within the fused ring systems.

94 opportunity to easily assemble 5,6- and 6,7-fused ring systems.

95 lustrates a divergent approach to synthesize fused-ring systems by CC activation/functionalization.

96 or the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety.

97 new benzimidazole and imidazo[4,5-c]pyridine-fused ring templates, represented by compounds 4 and 7,

98 s of this linear intermediate to produce the fused ring tetrahydroxynaphthalene (THN) skeleton.

99 et of the UV-vis absorption spectra when the fused-ring unit is located nearer to the periphery of th

100 ended conjugation into the electron-donating fused-ring units in nonfullerene acceptors is a promisin

101 ereochemistry of the bridgehead atoms of the fused ring using new MDOs self-assembled from both enant

102 For maximum diversity, the size of the fused ring varied from three to six atoms and contained

103 alkynylation, followed by formation of four fused rings via a zirconacyclopentadiene intermediate, a

104 In addition, fully saturated poly-fused rings were prepared from the carboacylation produc

105 ite the presence of the methylene bridge and fused ring, whereas the other showed lower affinity and

106 for compounds with high molecular weight and fused rings while high enrichment factors were obtained