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1 protein that is required to elicit membrane fusion.
2 ggering conformational changes essential for fusion.
3 1 EML4-ALK gene fusion and 1 KIF5B-RET gene fusion.
4 se lysines contributed to gB/gH-gL cell-cell fusion.
5 cristae structure and mitochondrial network fusion.
6 satellite cell proliferation, activation and fusion.
7 n a method developed to study yeast vacuolar fusion.
8 is required for outer mitochondrial membrane fusion.
9 expression with dysregulated gBcyt-mediated fusion.
10 ing the mechanism of virus-mediated membrane fusion.
11 vivo in a melanoma cells harboring the BRAF fusion.
12 y few milliseconds delay between docking and fusion.
13 appear to be able to regulate yeast vacuolar fusion.
14 s to host cell receptors to mediate membrane fusion.
15 an significantly enhance, cell-cell membrane fusion.
16 ctors that control mitochondrial fission and fusion.
17 (TGN) to endosome traffic and TGN homotypic fusion.
18 er functions at the plasma membrane to drive fusion.
19 , and low doses of methanol mildly inhibited fusion.
20 ndergo determination and eventually cellular fusion.
21 is sufficient to promote mammalian cell-cell fusion.
22 tate at the time of virus-host cell membrane fusion.
23 roteases to mediate virus-cell and cell-cell fusion.
24 olar compartment (PVC) and for TGN homotypic fusion.
25 r suppressing TMEM16F inhibited Env-mediated fusion.
26 myogenic development by repressing myoblast fusion.
27 ng 1 eye and with strategies used to recover fusion.
28 networks constantly remodeled by fission and fusion.
29 A receptor with a cytochrome b562-RIL (BRIL) fusion (A2AR-BRIL) in the intracellular loop 3 (ICL3) wa
32 microscopy, we now show that, after granule fusion, actin recovers at the synapse and no further sec
37 expression of EP300-ZNF384 and CREBBP-ZNF384 fusion altered differentiation of mouse hematopoietic st
39 NARE) proteins play a major role in membrane fusion and contribute to cell expansion, signaling, and
42 n WQ in blocking HIV-1 Env-mediated membrane fusion and had higher levels of binding affinity with NH
47 n and membrane solubilization of an MsrQ-GFP fusion and set up a purification scheme allowing the pro
48 ork maintenance requires continuous membrane fusion and that Yop1p favours the generation of highly c
49 -helix bundle that mediates synaptic vesicle fusion and used it to study vesicle fusion to a tethered
50 no residence time on plasma membrane before fusion and, to a lesser extent, also the predocked SGs.
52 nt-derived xenograft models (PDX) with RSPO3 fusions and in tumors with common CRC mutations such as
54 rafish embryogenesis coincides with myoblast fusion, and genetic deletion of myomixer using CRISPR/Ca
55 uired Fc gamma receptor engagement, bypassed fusion, and initiated signaling through both TLR7 and TL
60 for simultaneous detection of multiple gene fusions are limited by tedious and prolonged experimenta
61 re we report that, unlike BRAF fusions, CRAF fusions are unresponsive to both generations of RAFi, ve
64 e, using a reconstituted "flipped" cell-cell fusion assay, we show that lipid-anchored STX11 and its
66 in Saccharomyces cerevisiae Using cell-free fusion assays and light microscopy, we find that GTPase
68 e results imply that SERINC5 restricts HIV-1 fusion at a step prior to small pore formation by select
70 y expressing truncated versions of SS4 and a fusion between the N-terminal region of SS4 and GS in th
74 panol enhanced fusion, butanol also enhanced fusion but was less potent, and low doses of methanol mi
75 found to be required for virus-mediated cell fusion, but only for mutants that harbor syncytial mutat
77 -Ubp2-Rsp5 crosstalk regulates mitochondrial fusion by coordinating an intricate balance between Fzo1
78 ction with M1 protein, while the stunting of fusion by deacylated HA acting in isolation may be balan
80 of yeast vacuolar SNAREs into complexes for fusion can be studied in chemically defined reactions.
82 tochondrial fractions suggested that loss of fusion capacity targets fragmented mitochondria to the p
86 ine substitutions induced a 440% increase in fusion compared to that of the wild-type gBcyt while arg
88 priming step that renders synaptic vesicles fusion-competent, and their genetic elimination causes a
89 ansmembrane proteins that comprise the entry fusion complex (EFC), and had increased amounts of unpro
90 pre-fusion state and triggering to the post-fusion conformation is important for understanding F pro
91 tested in a paper-based assay format using a fusion construct consisting of an rcSso7d binding module
92 f mitochondria and mitochondrial fission and fusion contribute to this rejuvenation, but local protei
93 sms that regulate rates of crypt fission and fusion could provide insights into intestinal adaptation
94 ope, which is responsible for attachment and fusion, could aid in the development of a vaccine and/or
97 ression of the viral glycoprotein, but not a fusion defective mutant, is sufficient to cause CO2 sens
99 atients with MPNs, detection of the BCR-ABL1 fusion delineates chronic myeloid leukemia from classic
100 candidate materials will ensure that future fusion devices design components with optimal thermal st
101 into heterodimers, whereas the interparticle fusion drives assembled HNCs into ordered heterorod arra
102 Here we report that formation of the pre-fusion Env-CD4-coreceptor complexes triggers non-apoptot
104 image analysis to detect individual vesicle fusion events with approximately 27 nm localization prec
105 Furthermore, we show that these novel GSDMD fusions execute inflammasome-dependent pyroptotic cell d
107 eloped previously as a vector expressing RSV fusion (F) protein to confer bivalent protection against
108 uce a method, which we refer to as colloidal fusion, for fabricating functional patchy particles in a
110 s a proto-oncogene well known as part of the fusion gene BCR-ABL1 in the Philadelphia chromosome of l
113 study, we analyzed the status of TMPRSS2-ERG fusion genes and interstitial genes in tumors from a lar
116 tive guidance, (b) biopsy with MR imaging/US fusion guidance, and (c) in-gantry MR imaging-guided bio
118 rigins and the convergent reduction of notal fusion in more derived clades, presumably due to wing ro
119 analyses, we show that mitochondrial fission/fusion in reactive microglia is differentially regulated
120 during homotypic vacuolar lysosome membrane fusion in Saccharomyces cerevisiae Using cell-free fusio
121 ion in POMC neurons, promoting mitochondrial fusion in their neurites, and increasing POMC neuronal f
123 a transmembrane domain, can support membrane fusion in vivo is uncertain, as is the precise role of M
126 , we identified several novel oncogenic gene fusions in colorectal cancer that may drive malignant de
127 breakpoints of TMEM135-CCDC67 and MAN2A1-FER fusions in human prostate cancer or hepatocellular carci
128 e, called INTEGRATE-Neo, by identifying gene fusions in prostate cancers that may produce neoantigens
129 al basis for several activities required for fusion, including a C2B surface implicated in SNARE comp
132 n previous work, we have generated potent MV fusion inhibitors by dimerizing the F-derived peptides a
135 inding site of these aniline-based influenza fusion inhibitors, which significantly overlaps with the
139 sed and nonfused SMAs, we show that the ring-fusion introduces several beneficial effects on the prop
141 se tumors also frequently displayed ERG gene fusions involving alternative 5'-partners to TMPRSS2, sp
146 le arginine substitutions had wild-type-like fusion levels in an in vitro gB/gH-gL cell fusion assay.
147 increase the activation energy required for fusion, likely through an increase in membrane fluidity.
149 s identified within the epitopes in the EDII fusion loop likely explain the sequence and antigenic co
150 synthetic peptide corresponding to the HAP2 fusion loop was found to interact directly with model me
151 by patients with intermittent exotropia when fusion loss occurs spontaneously and to compare them wit
153 lial cells is mediated by the conserved core fusion machinery, composed of the fusogen gB and the rec
155 -terminal in-frame green fluorescent protein fusion may slow down the proteasome-mediated proteolysis
161 a rhodopsin (Rho)-guanylyl cyclase (GC) gene fusion molecule that is central to zoospore phototaxis i
164 We demonstrate the application of our gene fusion neoantigen discovery pipeline, called INTEGRATE-N
165 inhibit autophagosome formation or block the fusion of autophagosomes to endolysosomal compartments c
166 lar processes, including endosome formation, fusion of autophagosomes/amphisomes with lysosomes, and
167 ing film-coupled nanocubes in pixels using a fusion of bottom-up and top-down fabrication techniques
168 cC interacts with other cellular Cdks, but a fusion of CycC to Cdk8 reported here did not cause any o
169 T2 activity in HEK293T cells with an mCherry fusion of EGFP-K85AcK, and showed that this approach can
174 Vacuole generation involved the homotypic fusion of Munc13-4(+)/Rab7(+) SGs, followed by a merge w
175 ated skeletal muscle fibers form through the fusion of myoblasts during development and regeneration.
176 ll as triggered lamellipodia, spreading, and fusion of myoblasts through the signaling function of th
178 inally, reintroduction of linoleic acid, via fusion of phospholipid vesicles to mitochondria isolated
179 g the hyperfusogenic form of gB may regulate fusion of PILRalpha via a novel mechanism through gH/gL
180 ls that the unitary chromosome arose through fusion of six ancestral chromosomes, with extensive rear
183 es are entirely covered over by a continuous fusion of the cuticle, and consequently plants have decr
185 ancers, chromosomal rearrangements cause the fusion of the promoter and 5'-UTR of the androgen-regula
187 from P. putida reveals that the protein is a fusion of two distinct modules: an N-terminal sugar phos
188 in which the highly exothermic nature of the fusion of two heavy-quark baryons might manifest itself.
189 Munc13-4 promoted the Ca(2+)-stimulated fusion of VAMP8-containing liposomes with liposomes cont
190 he cellular SNARE system, which mediates the fusion of vesicles in healthy cells, and its relation to
194 mino acids at C-terminus does not promote LD fusion or TAG accumulation, while it still localizes to
198 Agena LungFusion panel and ThermoFisher NGS fusion panel) to those obtained from ALK, ROS1 and RET F
199 r group revealed the presence of PDGFRB gene fusions, particularly EBF1-PDGFRB, in almost one third o
200 e demonstrate the versatility of HUH-tags as fusion partners in Cas9-mediated gene editing and the co
201 scoidal nanolipoprotein particles (vNLPs) as fusion partners with cells ectopically expressing cognat
202 gnostic of particular sarcoma types, certain fusion partners, most notably EWSR1, are not tumor speci
205 assays show a strain-independent failure of fusion pore enlargement among H2 (A/Japan/305/57), H3 (A
207 se indicate that G100V/C103V retards initial fusion-pore opening, hinders its expansion and leads to
209 are released through fluctuating exocytotic fusion pores that can flicker open and shut multiple tim
211 rify that this affects the morphology of the fusion product and regulates transporter protein degrada
212 easier by automating the annotation of gene fusion products and generating easily interpretable visu
213 IV5 was engineered to express either the RSV fusion protein (F) or the RSV major attachment glycoprot
215 sses of EPIs that interact with the membrane fusion protein AcrA, a critical component of the AcrAB-T
216 5;17) translocation generates a PML-RARalpha fusion protein causative for acute promyelocytic leukemi
217 support further evaluations of pretargeting fusion protein cocktails as a strategy to enhance nanopa
218 vivo by Mef2c-Dam adenine methyltransferase fusion protein confirmed the link between cognitive enha
219 that immune responses to the more conserved fusion protein contribute to protection against heterolo
221 tial order of allergen and adjuvant within a fusion protein determines its immunologic characteristic
223 inal fusions, this virus expresses more VP26 fusion protein in infected cells and incorporates more V
225 in infected cells and incorporates more VP26 fusion protein into virus particles, and individual viru
226 rs show that a chemical inhibitor to a viral fusion protein is effective in reducing viral titre and
227 d Dusp1 suppressed tumor growth in a BCR-ABL fusion protein kinase-induced mouse model of chronic mye
228 ate that expression of either the endogenous fusion protein or a chimeric cDNA leads to the formation
230 the BAF complex is recruited by the EWS-FLI1 fusion protein to tumor-specific enhancers and contribut
232 have minimal impact on the properties of the fusion protein, as they have no propensity to form order
233 es of the Fas death receptor, the HIV-1 gp41 fusion protein, the influenza proton channel, and the MC
238 refusion and postfusion conformations of the fusion protein.IMPORTANCE Due to lapses in vaccination w
240 cells, we engineered CD200R immunomodulatory fusion proteins (IFPs) with the cytoplasmic tail replace
246 single-protein convenience of integrase-RDF fusion proteins make them potentially very advantageous
247 ji and Jurkat tumors, pretargeting with both fusion proteins markedly increased nanoparticle targetin
249 we tested whether immunoregulatory cytokine fusion proteins of IL-10/Fc, TGF-beta/Fc, or IL-2/Fc wou
251 that this spatiotemporal association of the fusion proteins selectively alters the methylation state
252 or genome targeting with Fkbp/Frb dimerizing fusion proteins to allow chemical-induced proximity of a
253 D-L1 antibodies, OX40 ligand, or GITR ligand fusion proteins, produced synergistic antitumor response
254 mixed-lineage leukemia gene (MLL) create MLL-fusion proteins, which could drive both acute lymphoblas
257 ctron poor units facilitates a visible light fusion reaction in >95% yield, whereas the cove-edge nat
259 rge of the lysine residues was necessary for fusion regulation, as alanine substitutions induced a 44
261 ether crossover formation actually energizes fusion remains unclear, as do the sequence of events sur
264 o localization of AtCPT7 fluorescent protein fusions showed that AtCPT7 resides in the stroma of meso
266 tages over strategies based on liquid phase (fusion) sintering that requires both oxide-free metal su
268 pects of correlative image overlay and image fusion specific to SIMS-based correlative microscopy are
270 e elements that control stability of the pre-fusion state and triggering to the post-fusion conformat
271 racterized viruses expressing amino-terminal fusions, this virus expresses more VP26 fusion protein i
272 (2+) release channel P2X4 regulates lysosome fusion through a calmodulin (CaM)-dependent mechanism.
273 y conserved Rho-GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone-induc
274 In contrast, patients with FGFR1 and JAK2 fusion TK genes exhibit a more aggressive course and var
275 ound that hyperfusogenic gB mutants enhanced fusion to a greater degree with the gB receptor the pair
277 ciples such as focus+context and visual data fusion to enable users to better understand the statisti
279 in which two heavy baryons (Lambdac) undergo fusion to produce the doubly charmed baryon and a neutro
286 method, ChimeRScope that accurately predicts fusion transcripts based on the gene fingerprint (as k-m
288 rf-like GTPase 8) and its effector homotypic fusion/vacuole protein sorting complex (HOPS) to (phago)
290 nd events (i.e. granule-to-granule homotypic fusion) was severely reduced in the absence of Munc13-4.
293 mation of the ER requires homotypic membrane fusion, which is mediated by a family of Dynamin-like At
295 cell wall deposition within 30 seconds after fusion with a sperm [3], thereby preventing further fert
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