ライフサイエンスコーパス: gag gene

1 ion is achieved using an RNA/codon optimized gag gene.

2 en the splice donor and the beginning of the gag gene.

3 and fusion of the remaining sequence to the gag gene.

4 ef, vpr, tat, and rev genes and parts of the gag gene.

5 vitro surrounding the beginning of the HIV-1 gag gene.

6 erferes with recombination efficiency in the gag gene.

7 oexpressing the full-length coevolved mutant gag gene.

8 o cause high-frequency mammary tumors to the gag gene.

9 lope-like open reading frame and an extended gag gene.

10 min NLS coding sequence was deleted from the gag gene.

11 it is inapplicable to analyses involving the gag gene.

12 ination codon in viral RNA at the end of the gag gene.

13 sociated with plasmids containing the native gag gene.

14 15, encoded by the relatively conserved EIAV gag gene.

15 s defects in the p17-encoding regions of the gag gene.

16 tinuous and to extend into the 5' end of the gag gene.

17 to a 925-nucleotide (nt) region of the EU-8 gag gene.

18 yses of nucleotide sequences of their env or gag genes.

19 ptide or cells transfected with HIV-1 env or gag genes.

20 with MuLV containing a mutation in the gPr80(gag) gene.

21 Analysis of a gag gene alignment, subregions of envelope including add

22 this element downstream of a PTC in the RSV gag gene also inhibits NMD.

23 etent MJ4/gag chimeric viruses, encoding the gag gene and 142 nucleotides of pro derived from viruses

24 designated TRE (GP), near the 3' end of the gag gene and preceding the pol gene of SFV-1.

25 ogaster, has high sequence similarity to the gag gene and untranslated regions of HeT-A, the most abu

26 through the domestication of retrotransposon Gag genes and mediates intercellular messenger RNA trans

27 on attenuated VSV vectors expressing env and gag genes and tested it in rhesus monkeys.

28 levels, promotes translation of the HIV-1 5' gag gene, and alters splicing at the A2 site.

29 Live vectors that carry an intact gag gene are capable of eliciting HIV pseudovirion parti

30 , spanning the long terminal repeats and the Gag gene, are excised in vivo, resulting in elimination

31 es in the HIV 5iota long terminal repeat and gag gene as well as in the beta-globin gene and LCR.

32 5' long terminal repeat and the start of the gag gene at position 1659 to 1694 completely abrogated g

33 In this study, we established a gag gene-based dual-emission fluorescence resonance ener

34 iral assembly in the first two-thirds of the gag gene by making a series of chimeras between enJS56A1

35 in part upon a cis-acting element within the gag gene called the negative regulator of splicing (NRS)

36 ted BALB/cByJ CTL directed against defective gag gene constructs of the LP-BM5 virus complex that cau

37 The Rous sarcoma virus gag gene contains a cis-acting negative regulator of spl

38 R-9 deletion is located in the region of the gag gene corresponding to the matrix (MA) protein as wel

39 ontrast, LR-9, which lacks the 42-nucleotide gag gene deletion of DeltaLR-9, does not cause a high fr

40 w that L. monocytogenes expressing the HIV-1 gag gene efficiently provides a strong stimulus for Gag-

41 is a product of proteolytic cleavage of the gag gene encoded polyprotein (pr55gag) and is formed whe

42 otein gene (gfp) of Aequorea victoria or the gag gene (encoding p17-p24) of human immunodeficiency vi

43 s) suppressed HIV-1 p24 production and HIV-1 Gag gene expression and decreased expression of miR-155

44 und that, similar to the other retroviruses, gag gene expression of MuLV and XMRV depends on post-tra

45 with plasmid DNA encoding SIVmac251-env and gag genes followed by an intranodal tonsil MALT boost wi

46 ofected with a plasmid expressing the entire Gag gene, following proteolytic cleavage of the Gag prec

47 own about the variability of the full-length gag gene for HIV isolated from a single individual.

48 ch expressing the same codon-optimized HIV-1 gag gene for immunogenicity in rhesus monkeys.

49 al SIVsm env genes in the troop but having a gag gene from another, distinct SIV.

50 These strains appear to be mosaics, with the gag gene from clade A and the envelope from clade E; the

51 ence has been noted previously in studies of gag genes from other retroelements.

52 -1 capsid (CA) proteins encoded by the viral gag gene have been obtained by incubation of histidine-t

53 Placement of the gag gene in the first position of the VSV genome was ass

54 ound avian sarcoma and leukosis virus (ASLV) gag genes in 19 species of birds in the order Galliforme

55 ound avian sarcoma and leukosis virus (ASLV) gag genes in 26 species of galliform birds from North Am

56 Here, we searched for other intact gag genes in non-primate mammalian lineages.

57 placentation, there are examples of co-opted gag genes including one we recently discovered in simian

58 of 30 nt derived from the 5' end of the p17 gag gene INS element (5' INS) is functional and permits

59 uced the simian immunodeficiency virus (SIV) gag gene into several of these novel BCG strains, we obs

60 ene mutations (Mncp), and positioning of the gag gene into the first position of the viral genome (ga

61 ogenous location in the Rev-dependent (late) gag gene into the Rev-independent (early) nef gene with

62 The gag gene is highly polymorphic across HIV-1 subtypes and

63 introduced at various positions in a mutant gag gene lacking the PPPY motif.

64 Sequencing of the gag genes, LTRs, and untranslated regions of several ev/

65 assembly itself for two previously described gag gene mutants.

66 particles is mediated by the product of the gag gene; no other retroviral gene products are necessar

67 (MHR) is a highly conserved sequence in the gag gene of all retroviruses, including HIV-1.

68 tions of an effective shRNA that targets the gag gene of HIV-1.

69 d a portion of CA sequences derived from the gag gene of Mo-MLV.

70 Deletion of a portion of the gag gene of pCMVgag-2, containing a cis-repressing inhib

71 ous retrovirus (ERV) sequence related to the gag gene of the MuERV-L ERV family.

72 DNA sequencing of the SIV(mac251) Gag gene of the two stocks used in our study revealed SI

73 are phosphoproteins that are encoded in the gag gene of the virus.

74 Mutations can accumulate in the protease and gag genes of human immunodeficiency virus in patients wh

75 c knuckle region, a region characteristic of gag genes of most replication-competent retroelements.

76 comprehensive functional map of a retroviral gag gene, our study demonstrates the abundance of inform

77 ng a U6A shift site at the distal end of the gag gene performing a programmed -1 ribosomal frameshift

78 n immunodeficiency virus type 1 (HIV-1) Pr55(gag) gene product directs the assembly of virions at the

79 y been shown to promote translation of their gag gene products by internal ribosome entry.

80 The expression of both the env and gag gene products of human immunodeficiency virus type 1

81 cies is also translated, producing the viral gag gene products.

82 Sequences of HIV-1 envelope and gag genes remained markedly homogeneous, indicating litt

83 Viral gag gene replacements are influenced by host restriction

84 e of viral replication by detection of viral gag gene RNA in reverse transcriptase-PCR assays on vira

85 robe for diagnosis is demonstrated using the gag gene sequence of the human immunodeficiency virus ty

86 e detection scheme is demonstrated using the gag gene sequence of the human immunodeficiency virus.

87 een ASLV phylogenies based on a total of 110 gag gene sequences and ASLV-host phylogenies based on mi

88 ic criteria for CFS and found MLV-like virus gag gene sequences in 32 of 37 (86.5%) compared with onl

89 R (RT-nPCR) assay for the detection of viral gag gene sequences in plasma from EIAV-infected horses.

90 with all viral variants, irrespective of the gag gene sequences.

91 Although the ev/J gag gene showed a relatively weak relationship (46% iden

92 The resulting modified gag gene showed increases in p55(Gag) protein expression

93 rameshift mutations were introduced into the gag gene so that parental viruses do not express full-le

94 of sequences from the U5 to upstream of the gag gene start codon of diverse HIV-1 strains by using n

95 not that induces ribosome suppression of the gag gene stop codon in Moloney murine leukemia virus has

96 say and partial sequence analysis of env and gag genes strongly suggests that all the HIV-infected su

97 Because certain regions of the gag gene, such as p24, are highly conserved among human

98 divergent primary HIV-1 isolates via env and gag gene targets.

99 therapeutic strategies have been directed at gag gene targets.

100 determine the specific sequences within the gag gene that contribute to tumor induction, we construc

101 Deletions within the gag gene that encompass the NRS also lead to increased r

102 a set of five conserved regions in the HIV-1 gag gene, the method could specifically detect HIV-1 in

103 expressing full-length and truncated F-MuLV gag genes, the antigenic epitope recognized by the FBL-3

104 d by targeting a conserved region within the Gag gene to compare NOD with T1D-resistant mice or diffe

105 However, adding the 5' half of the gag gene to the 5' UTR strongly facilitates the packagin

106 ogenetic relationships that parallel env and gag gene variation.

107 ptimized human immunodeficiency virus type 1 gag gene was examined in baboons.

108 human immunodeficiency virus type 1 (HIV-1) gag gene was substituted for the capsid gene (P1).

109 human immunodeficiency virus type 1 (HIV-1) gag gene was synthesized and cloned into the packaging v

110 iciency virus type 1 (HIV) Rev/RRE-dependent gag gene was used as a reporter to analyze various SNV s

111 , and one stable stem-loop structure (in the gag gene) was predicted in the secondary signal region.

112 Codon-optimized sequences from the HIV gag gene were inserted into alternative DNA vaccine vect

113 onstructed in which domains within the HIV-2 gag gene were replaced by the corresponding domains in H

114 the capsid region from the coevolved mutant gag gene were sufficient to achieve full recovery of rep

115 oHelix Corporation), which targets the HIV-1 gag gene with use of isothermal reverse-transcription he