ライフサイエンスコーパス: gain

1 n in the small intestine and impaired weight gain.

2 ifts of vRFs, rather than changes in size or gain.

3 ersally prohibit harming others for personal gain.

4 evels and suppression of diet-induced weight gain.

5 s fewer total treatments for the same health gain.

6 educed microglial activation and body-weight gain.

7 h-fat diet, even prior to significant weight gain.

8 responsivity in line with compromised neural gain.

9 networks relevant to food craving and weight gain.

10 ted with increased caloric intake and weight gain.

11 ictures but not for cues predicting monetary gains.

12 are unable to replicate post-FISP production gains.

13 00 (95% CI: US$162,000, US$667,000) per QALY gained.

14 t-effectiveness ratio (ICER) of $94,917/QALY gained.

15 sight into the ribozyme-mediated cleavage is gained.

16 s-to-pay (WTP) threshold of $50 000 per QALY gained.

17 s to pay threshold of $100,000 per life-year gained.

18 each strategy, and incremental cost per QALY gained.

19 were measured in quality-adjusted life-years gained.

20 ,000 (95% CI: US$14,000, US$24,000) per QALY gained, 50% NSP coverage could avert up to 35,000 (95% C

21 5,000 (95% CI: US$7,000, US$76,000) per QALY gained, 50% Test & Treat coverage could avert up to 6,70

22 In order to gain a better understanding of how resistance to DNA met

23 g pace and are revolutionizing approaches to gain a better understanding of human diseases.

24 se III clinical studies, it is imperative to gain a better understanding of its mechanisms of protect

25 To gain a better understanding of the relationship between

26 dins, LMW subunits and antigenic epitopes to gain a better understanding of the technology at a molec

27 To gain a deeper understanding of the evolution of gene tra

28 ssed truncated forms and protein chimeras to gain a deeper understanding of toxin specificity and sta

29 To gain a fundamental understanding of their properties on

30 )), A1 (117 g L(-1)), and L2 (76 g L(-1))-to gain a genome-wide view of the mechanism of citrate accu

31 The "gamification" of science has gained a lot of traction in recent years, and games that

32 letters from baseline, and they subsequently gained a mean (SD) of 17.4 (9.7) (VISTA) and 13.6 (8.6)

33 dictioning new drug-target interactions have gained a tremendous interest in recent times.

34 Gaining a better understanding of the WGS data, and how

35 Finally, we discuss how gaining a deeper understanding of GxEs may translate int

36 t well understood and carries importance for gaining a fundamental understanding of brain plasticity.

37 -the process by which trainees in any region gain access to international training (electronic or in-

38 sought to determine how assembled tau seeds gain access to the cytosol and whether this access trigg

39 zed at P2 but not at P9, E. coli K1 bacteria gain access to the enterocyte surface in the mid-region

40 on that lead to differences in average daily gain (ADG), rumen fluid metabolomic analysis by LC-MS an

41 in imputation panels and exemplify the power gains afforded by population isolates.

42 xperience seem to induce a selective sensory gain along acoustic dimensions that are functionally-rel

43 The extremely high gain also leads to significant amplification of backscat

44 a means to increase functional diversity and gain an evolutionary advantage against competing systems

45 culminating in significantly reduced weight gain and adiposity.

46 Animals in group 1 continued to have weight gain and biochemical analyses comparable to wild-type pi

47 Attention to symptoms of weight gain and dyspnea are central tenets of patient education

48 c medications often result in adverse weight gain and hypoglycemic episodes.

49 Thus, analyses of gene gain and losses, gene architectures, synteny and other g

50 ht be early events that contribute to weight gain and obesity development.

51 Despite enhanced weight gain and plasma lipid levels compared with Apoe(-/-) con

52 l review medications that can lead to weight gain and potential alternatives, currently approved anti

53 s commonly attributed to a modulation of the gain and tuning of feature-selective units in visual cor

54 as olanzapine often induce excessive weight gain and type 2 diabetes.

55 on the long-term benefits (e.g., life-years gained and mortality reduction) and harms (e.g., overdia

56 ollars per quality-adjusted life year (QALY) gained and number of fragility fractures.

57 a hallmark of diseases involving chromosome gains and losses, such as Down syndrome and cancer.

58 dine (AraC) blunted food intake, body weight gain, and adiposity.

59 s associated with sedentary behavior, weight gain, and higher triglyceride and cholesterol levels.

60 maternal anthropometrics, gestational weight gain, and preterm birth rate, but not in maternal age, p

61 ,000 (95% CI: US$15,000, US$48,000) per QALY gained, and 50% PrEP coverage could avert up to 37,000 (

62 hus for the first time provide complementary gain- and loss-of functional evidence in vivo for a cofa

63 Significantly, both RhoA GTPase gain- and loss-of-function mutations have been discovere

64 ucial in dominant diseases that feature both gain- and loss-of-function pathologies or have a heterog

65 edge, all companies involved synergistically gained approximately 20% more rules from the shared tran

66 18,600 CVD deaths (95% CI: 17,600, 19,500), gaining approximately 280,100 LYGs by 2030.

67 However, these gains are fragile, and coverage is far from optimal.

68 The gain arises when a saved seed is allocated to a node dif

69 hs up to 1.5 kHz whilst maintaining internal gain as large as 10(6) .

70 Copy-number gain at 3q resulted in increased MAP3K13 mRNA in HNSCC t

71 NF-kappaB has recently gained attention as a mediator of complex psychiatric ph

72 lyphenol found in various plant sources, has gained attention as a possible agent responsible for the

73 Phytochemicals have gained attention as alternative therapeutics for managin

74 lated degradation products or impurities has gained attention in the last years and is relevant to as

75 dairy equivalent is adequate for normal bone gain between ages 8 and 16 y.

76 The difference in QALYs gained between the test and no test options was 4758.62

77 obtained by combining a one-dimensional loss/gain bilayer and one or two thin polarization-converting

78 ve tumor load, suggesting most benefit to be gained by early conversion to an mTOR inhibitor-based ma

79 of underlying evidence and potential benefit gained by early detection and appropriate management.

80 mics in mangroves and tidal marshes has been gained by monitoring a wide range of different sites, lo

81 s been covariation between the amount of DNA gained by transposition and lost by deletion during mamm

82 n phenotypic measurements and omit potential gains by integrating genetic selection into existing bre

83 constant of proportionality (i.e., feedback gain) called the navigation constant (N).

84 The information thus gained can be used to generate hypothesis which can be e

85 Combining loss and gain components in one photonic heterostructure opens a

86 Recently copy number variation (CNV) has gained considerable interest as a type of genomic/geneti

87 urfaces with metal oxide nanostructures have gained considerable interest in applications such as sen

88 ng motivation and sensitivity to reward loss/gain consistent with human depression.

89 anization of functional elements in order to gain control over the spatial and temporal elements of f

90 ficacy, including heterosynaptic plasticity, gain control, output balancing, activity normalization o

91 t for diabetic people and patients in weight gain control.

92 er transconductance (g m ) and unity current gain cut-off frequency (f T ) than GFETs.

93 , gene expression, viremia level, and weight gain data to identify genetic polymorphisms that are ass

94 een kleptoparasitic losses and the energetic gains derived from killing larger prey.

95 ries of kinetic experiments was conducted to gain detailed insight into the reaction mechanism.

96 treats residual EOC after cyto-reduction by gaining direct access into the peritoneal cavity, enabli

97 -induced tumors, inflammation-induced tumors gained DNA methylation at CpG islands, some of which are

98 B, as well as cascaded four-wave mixing with gain down to the third idler is observed and attributed

99 shape animal movement and presumably, energy gains during migration.

100 low direct access to the study of perovskite gain dynamics and material robustness.

101 ed no significant interaction between weight gain effect and age, sex, history of breastfeeding, prio

102 treatment could be contributing to elevation gain, either directly through reduced soil shrinkage or

103 Computerized cognitive training is gaining empirical support for use in the treatment of sc

104 pansions in the context of climate change to gain essential mechanistic insights into insect invasion

105 ased on this study, children with MAM mainly gain fat-free tissue when rehabilitated.

106 nt regions, and at least 5-times sensitivity gain for regions separated by one diameter away from the

107 was euro6840.75 (95% CI 2545-2759) per QALY gained for a treatment efficacy of 20% and euro4243 per

108 Functional knowledge has been gained for its conserved methylated DNA binding N-termin

109 atment efficacy of 20% and euro4243 per QALY gained for treatment efficacy of 50%.

110 findings will allow acceleration of genetic gains for key traits to improve yield and sustainability

111 sion implies the practicability to construct gain-free omnidirectionally non-reflecting absorbers.Ref

112 We assessed weight gain from birth until 6 mo.

113 e subjective value a communicator expects to gain from sharing.

114 evidence that high-risk patients had more to gain from treatment, we were unable to replicate any gen

115 tively correlated with the mass that spiders gained from prey, but not with the number of prey killed

116 seven transmembrane (7TMR) function has been gained from the comparison of experimental data to recep

117 nsfer processes, discusses the new knowledge gained from these approaches about both the evolutionary

118 Knowledge gained from these studies could help in the design of ne

119 More generally, the insights gained from this structure-reactivity relationship may a

120 insights into EpiSC gene regulatory networks gained from this study are highly relevant to early stag

121 We find many significant gains from promoting rural biogas stoves in a context in

122 erior parietal, cortex eliminated behavioral gains from rehabilitative training.

123 ratios (cost per quality-adjusted life year gained) from the societal perspective across a range of

124 llular lipids in virus replication have been gaining full attention only recently.

125 as found that attention displayed a response-gain function, whereas consciousness displayed a contras

126 nd, attention manifests itself as a response-gain function, whereas consciousness manifests itself as

127 , whereas consciousness displayed a contrast-gain function.

128 consciousness manifests itself as a contrast-gain function.

129 nsition metal dichalcogenides (2D TMDs) have gained great interest due to their unique tunable bandga

130 ronic diarrhea, weight loss (or insufficient gain), growth failure, or anemia.

131 3% had UDCVA of 20/25 or better, 100% vs 76% gained >/=1 lines, and 59% vs 43% were within +/-0.13 D

132 weight (kg)/height (m)2), gestational weight gain (GWG), birth size, and childhood growth factors wit

133 Health-adjusted life years (HALYs) gained, healthcare costs saved, and out-of-pocket costs

134 When loading MK2i, 1) the HT depot surface gained high MK2i-loading efficiency through charge-charg

135 rived from separate, complementary assays to gain higher-confidence insights into cellular states.

136 by suppressing the mode that has the highest gain (i.e. lies under the peak of the gain spectrum curv

137 Correlation analysis and information gain identified a 14 gene expression signature related t

138 detector computed tomography (MDCT) has also gained importance in diagnosing gastrointestinal bleedin

139 rengthened market orientation have gradually gained importance in the past 25 years; these reforms we

140 E3 ligases are gaining importance as targets to small molecules, both f

141 omal protein reserve to maximize the overall gain in biomass during the feast.

142 markers as an attempt to accelerate genetic gain in breeding programs of both animals and plants.

143 The gain in EpMM was larger when CPs were listed with unacce

144 of an adapting internal model of visuomotor gain in motor cortex while two macaques performed a reac

145 r-resolution microscopy offers a significant gain in resolution over traditional optical microscopy,

146 Weight gain in the trimethoprim-sulfamethoxazole group and the

147 omplex compounds by applying prior knowledge gained in new settings.

148 rks for the creation of unique structures is gaining in popularity.

149 ining exercises were associated with greater gains in auditory perceptual learning (r=-0.5 and r=-0.6

150 rates but was associated with self-reported gains in parental knowledge that were retained for 7 mon

151 FAK and mutant EGFR, EGFRvIII, and abrogated gains in secreted proteases, MMP-2 and MMP-9, following

152 tural zones showed small losses and even net gains in SOC.

153 tional intervention pilot study compared the gains in teamwork skills for midlevel surgical residents

154 Gains in VO2 max demonstrate large inter-individual vari

155 geable metal-air batteries, an issue that is gaining increasing interest in recent years.

156 Dpp4 was increased in mice with high weight gain, independent of liver fat content.

157 g, suggesting the possible role of a current-gain inducing mechanism similar to those seen in photode

158 ight and gestational age, with weekly weight gain initiating examinations when the risk cut point is

159 me obtained by excision repair sequencing to gain insight into factors that affect UV-induced DNA dam

160 To gain insight into spanin function, pseudorevertant allel

161 To gain insight into the cellular and molecular interaction

162 In order to gain insight into the mango cuticle biogenesis and ident

163 To gain insight into the molecular basis for how these muta

164 To gain insight into the molecular mechanisms associated wi

165 To gain insight into the physiological mechanisms involved,

166 To gain insight into the TolA-pIII complex, we developed a

167 To gain insight into this Hg(II) biouptake pathway, we have

168 To gain insight into this phenomenon, we analyzed a cohort

169 ution binding data and crystal structure, we gained insight on how the probe senses ligand-induced co

170 , fitness, and sleep from smartphones and to gain insights into activity patterns associated with lif

171 Here, we aimed to gain insights into the genetic architecture of biomarker

172 To gain insights into the molecular mechanisms of Lrp4 func

173 erence methods, are improving our ability to gain insights into the population history of species.

174 To gain insights, we developed a signature, "CA20", compris

175 We gained insights into the mechanism of acyl hydrolysis by

176 ion in fear- and anxiety-based disorders has gained interest as growing literature indicates that pro

177 , the available technologies, irradiation is gaining interest as a feasible preservation method.

178 orate heterotypic cellular communication are gaining interest as they can recapitulate key features r

179 he contrast between the abundance of insight gained into the events that constitute the metastatic ca

180 Although some insights have been gained into the pathogenesis of these diseases, it is no

181 se that the dispersion is enhanced while the gain is further reduced.

182 It is not absorptive, on the contrary, weak gain is presented; ii) It can be improved by the Doppler

183 evise drug discovery approaches, but also to gain knowledge on TEAD regulation.

184 In the classic gain/loss framing effect, describing a gamble as a poten

185 ies richness and composition through species gains, losses and changes in abundance, will better reve

186 Effectiveness was measured in life years gained (LYG).

187 deaths prevented or postponed and life-years gained (LYGs) over the study period, stratified by age,

188 many branches of science, but our ability to gain mechanistic insight and effectively conduct numeric

189 We sought to gain mechanistic insight into how IL-17A can influence I

190 To gain mechanistic insight into the CYP121-catalyzed react

191 However, their applications as optical-gain media are complicated by a non-unity degeneracy of

192 cidence usually requires the introduction of gain media into the system.

193 under a 1.6% uniaxial tensile strain as the gain medium.

194 gnosis and treatment on quality of life have gained momentum in the past 10 years.

195 endogenous targeting systems is increasingly gaining momentum.

196 on of robotic pancreatoduodenectomy (RPD) is gaining momentum; however, its impact on major outcomes,

197 -based in situ chemical oxidation (ISCO) has gained more attention in recent years due to the generat

198 etic and genomic data set through iFORM/eQTL gain new discoveries on the genetic origin of gene expre

199 feature with early postnatal onset, we would gain new insights into the mechanisms by which maternal

200 The goal of this study was to gain new insights into the underlying genetics of body f

201 Arg8 ligand-pair was further investigated to gain novel insights into the oxytocin/vasopressin peptid

202 After 3 years, surgery led to a gain of 0.199 QALYs compared with no surgery at an incre

203 be directly because of PrEP), and lead to a gain of 40 000 discounted QALYs over an 80-year time hor

204 Optical parametric gain of 42.5 dB, as well as cascaded four-wave mixing wi

205 d comparative genomic hybridization (n = 3), gain of 6p was found in 2 cases and gain of 8 in 2.

206 (n = 3), gain of 6p was found in 2 cases and gain of 8 in 2.

207 human subjects demonstrate that attentional gain of cortical responses can sufficiently account for

208 Here, we report on the modulation of the gain of excitatory signals from the AE by signals from i

209 ll inter-eye distance), and reduction of the gain of feature tuning for partial face stimuli compared

210 only on the effects of mutant p53 oncogenic gain of function but also on the mechanisms underlying n

211 Individuals possessing gain of function mutations in the kinase domain such as

212 xpansion which has been assumed to result in gain of function, predominantly, for the ATXN2 protein.

213 oteins are toxic to cells independent of RNA gain of function.

214 ancer cells differ from normal cells in both gain of functions (i.e., upregulation) and loss of funct

215 ion can enhance neuron excitability, whereas gain of GIRK function can reduce neuronal activity.

216 Loss and gain of IL-10RA expression directly correlates with IEC

217 itivity analysis showed that the incremental gain of QALY ranged from 0.0041 to 0.030.

218 rons of the prefrontal cortex display higher gain of somatic excitability, responding with a higher n

219 in the prefrontal cortex (PFC) modulates the gain of the PLR, changing how a simple reflex circuit re

220 d assembly causes disease and represents the gain of toxic function.

221 horizon, ticagrelor was associated with QALY gains of 0.078 and incremental costs of $7,435, yielding

222 We assess whether gains of ESD are associated with higher diversification

223 ld) in clinically actionable genes including gains of FGFR4 (n = 6 [30%]), FLT1 (n = 4 [20%]), AURKA

224 support across the life cycle, securing the gains of investment in the first 1000 days, enabling sub

225 permanently secure and sustain the enormous gains of polio eradication forever.

226 nd in <1.5% of brains, including copy number gains of PRPH that were overrepresented in AD.

227 mulate in cancer cells and may confer unique gain-of-function (GOF) activities to promote tumorigenic

228 mutated in a variety of cancers to confer a gain-of-function activity resulting in the accumulation

229 By using both gain-of-function and loss-of-function approaches, we dem

230 Using gain-of-function approaches, we found that overexpressio

231 This gain-of-function CRY1 variant causes reduced expression

232 e model with a naturally occurring WS-linked gain-of-function Cxcr4 mutation, we explored the possibi

233 The pairing of both loss- and gain-of-function datasets reveals complex gene networks

234 Consistent with a gain-of-function effect, ectopic expression of the 2 ide

235 Finally, gain-of-function experiments show that Pth4 can alter ca

236 Notably, Galpha13 gain-of-function inhibits Akt activation and osteoclasto

237 Gain-of-function missense mutations in NLRP3 result in a

238 torage disorder mucolipidosis type IV, and a gain-of-function mutation (Ala419Pro) in TRPML3 gives ri

239 It is shown that the gain-of-function mutation of TTP impairs IL-10-mediated

240 Gain-of-function mutations in iRHOM2 underlie Tylosis wi

241 Histone Lys-to-Met (K-to-M) mutations act as gain-of-function mutations to inhibit a wide range of hi

242 , and p.Val162del lack-of-function or p.A69T gain-of-function mutations.

243 associated PIEZO1 variants exhibit a partial gain-of-function phenotype with generation of mechanical

244 the developing mouse brain mimicked a Notch gain-of-function phenotype, suggesting that Myt1l allows

245 mechanisms are proposed to cause FXTAS: RNA gain-of-function, where CGG RNA sequesters specific prot

246 ibit bristle cell fate phenotypes reflecting gain-of-Notch signaling, H/+ does not rescue mir-279/996

247 causes toxicity and neurodegeneration via a gain-of-toxic function mechanism; either through direct

248 Here we experimentally demonstrate high-gain optical parametric amplification using USRN, which

249 ropensity for both receptors to coordinately gain or lose binding in the presence of progesterone.

250 ssociations between neighborhood supermarket gain or loss and glycemic control (assessed by glycated

251 g effect, describing a gamble as a potential gain or loss biases people to make risk-averse or risk-s

252 sured as quality-adjusted life-years (QALYs) gained or lost by investing resources in a new strategy

253 SF3R extracellular domain resulted in either gain- or loss-of-function changes, part of which was att

254 WAND can achieve up to 21-times sensitivity gain over a standard external detector for immediately a

255 genome, with only seven Y-linked genes being gained over the past 63 million years (0.12 gene gains p

256 vity and specificity, with clear performance gains over the latest method.

257 ital cardiac arrest achieved larger survival gains over time.

258 ed over the past 63 million years (0.12 gene gains per million years).

259 Light-controlled release has gained popularity in recent years; however, a major limi

260 Optical coherence tomography and OCTA are gaining popularity in pediatric retinal imaging.

261 Robotic rectal cancer surgery is gaining popularity, but limited data are available regar

262 2 452) per quality-adjusted life-year (QALY) gained, pound372 207 (268 162-1 903 385) per death avert

263 d to be effective in suppressing body weight gain relative to control in a diet-induced obese dog mod

264 sonance "strength") rises profoundly as loop gain rises toward 1.

265 aques performed a reaching task in which the gain scaling between the hand and a presented cursor was

266 c inputs onto MGB neurons, likely increasing gain selectively and improving temporal clarity.

267 nstrate that the stabilization of widespread gain signals affecting already available cognitive proce

268 Recently, Criegee intermediates have gained significant attention since a new preparation met

269 bone, nanodopant composite biomaterials are gaining special attention for their ability to guide bon

270 ighest gain (i.e. lies under the peak of the gain spectrum curve) and switch the lasing action to ano

271 al and evolutionary implications of symbiont gains, switches, and replacements, and identify future r

272 with photosynthetic stems have extra carbon gain that can help cope with the detrimental effects of

273 might represent a substrate for how odorants gain the quality of tastants.

274 ss >/=8 mm (5.14, P < 0.001), whereas for 8q gain, the OR was highest for ciliary body location (102.

275 We thereby reduce the optical gain threshold and demonstrate continuous-wave lasing fr

276 Such information is frequently gained through analyses of isolated viral envelope antig

277 f those (39% N = 46) maintaining a 10-letter gain throughout the 24 months.

278 ther variables that are predictive of weight gain to inform the design of obesity-preventive programs

279 We further use the insight gained to explain the formation of the unusual structure

280 enting one of the largest optical parametric gains to date on a CMOS platform.

281 each participant, we modified the interface gains to restore a higher level of upper body mobility.

282 f hypodermic needle to micron-scale size has gained tremendous interest among researchers.

283 To gain understanding of MRN in cancer, we engineered mice

284 vide a new ALS model with the opportunity to gain unique perspectives into mechanisms of neurodegener

285 By harnessing multiomics approaches, we may gain valuable insights into their potential function.

286 eal extensive variation in the amount of DNA gained via lineage-specific transposition, but that DNA

287 cemic control at baseline, while supermarket gain was associated with marginally better HbA1c outcome

288 The most recurrent expression gain was ERBB2/HER2, which showed a greater than 2-fold

289 Keratinized tissue thickness gain was significant only in CM-treated groups (P <0.05)

290 Weight gain was similar in the lower- and higher-protein groups

291 The non-linear gain was typically 10-30 dB and was broad-band rather th

292 remental cost per quality-adjusted life-year gained was $9333 (95% CI 3862-28 169; 2015 international

293 ile hyperleptinemia and pre-pregnancy weight gain were present in all db/+mice across the four studie

294 INTERPRETATION: National coverage gains were accelerated by important increases among poor

295 parental age nor maternal gestational weight gain, were associated with NAFLD in male offspring.

296 tantially greater lean mass and leg strength gains when PS and RET were used than with RET alone, wit

297 dm1 in excitatory neurons facilitated weight gain while exacerbating energy expenditure.

298 measures has resulted in huge public health gains, while support for translational research is leadi

299 Targeted covalent inhibitors have gained widespread attention in drug discovery as a valid

300 epatitis B surface antigen loss and anti-HBs gain, with normalization of serum aminotransferases off