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1 II, are released and/or phagocytic proteases gain access.
2 ror-free because error-prone repair does not gain access?
3 ot gain access to these regions, or does AID gain access, but the resulting uracils are repaired erro
4 suggest that, in these lesions, meningococci gain access from the capillary lumen to the peripheral e
5 ameliorated Nefud Desert interior, possibly gaining access from multiple directions, either using ro
6 suggest that CMs, most fatty acids of which gain access into cardiomyocytes through LPL-mediated hyd
7 trategy that nonenveloped viruses can use to gain access into cells and how viruses usurp disparate h
9 eton rearrangements and membrane ruffling to gain access into nonphagocytic cells, where it can repli
10 amically controlled way, it is imperative to gain access into the intrinsic dynamics of the supramole
12 directly across the plasma membrane but also gain access through endocytic pathways that are yet to b
13 ther a robotic system and/or laser, surgeons gain access through the mouth via minimally invasive tec
14 r total utilization, suggesting that the TAG gaining access through receptor-mediated pathways is pre
16 trast two-dimensional objects in particular, gain access to a predominantly left-lateralized language
17 trained to press one lever (seeking; SL) to gain access to a second lever (taking; TL) linked with f
18 ubiquitination of DSL ligands allows them to gain access to a select, Epsin-dependent, endocytic path
20 ty of the SPROUTS database is the ability to gain access to a variety of structural analyses at one p
21 sely functionalized azetidine ring system to gain access to a wide variety of fused, bridged, and spi
22 ogic mechanism through which SZ chondrocytes gain access to active TGF-beta: the synovium and articul
24 external protons permeate TRPM2 channels to gain access to an intracellular site that regulates chan
25 ing that tissues permissive for ERV activity gain access to an otherwise silenced source of regulator
27 anochain) that possesses a unique ability to gain access to and be deposited at micrometastatic sites
28 nsport from cells requires that they readily gain access to and function within interstitial fluid.
29 onducting hemichannels that allow protons to gain access to and leave buried carboxyl groups on the p
32 holin-mediated disruption of the membrane to gain access to attack the cell wall, signal anchor relea
34 roup members is essential for individuals to gain access to benefits from engaging in intergroup conf
36 e capacity of this opportunistic pathogen to gain access to BL receptors, leading to a successful col
37 Our results raise a possibility that E1A may gain access to cellular promoters through PLDLS-dependen
38 spindle assembly commences when microtubules gain access to chromatin after nuclear envelope breakdow
40 y factors and transcriptional machinery must gain access to chromatin to extract genetic information.
42 ired rats to solve a new puzzle every day to gain access to cocaine, which they then self-administere
44 where Bcd influences chromatin structure to gain access to concentration-sensitive targets at high c
50 hods and technology, we are able to reliably gain access to data in larger quantities, dimensions and
51 where otherwise normal tissue was removed to gain access to deeper hippocampal pathology in patients
52 ol II) must break the nucleosomal barrier to gain access to DNA and transcribe genes efficiently.
54 rations must occur for DNA repair factors to gain access to DNA lesions and restore original chromati
55 roviding the entry port for exogenous DNA to gain access to DNA receptors associated with the cytopla
58 Claisen rearrangement is a known protocol to gain access to functionalized allenes through the [3,3]-
60 cessing centers where many different enzymes gain access to genomic substrates by exploiting direct i
63 echanisms employed by bacterial pathogens to gain access to host iron sources, the role of iron in ba
64 ite on CR1 by which P. falciparum merozoites gain access to human erythrocytes in a non-sialic acid-d
65 ID requires single-stranded DNA and needs to gain access to Ig loci, with RNA pol II transcription po
67 sure that only fully mature, immunogenic DCs gain access to inductive sites, where they might prime e
68 re, we determined whether antibodies rapidly gain access to integrin overexpressed on the abluminal (
69 -the process by which trainees in any region gain access to international training (electronic or in-
75 e receives protons from water molecules that gain access to its hydrophobic environment and transduce
77 d for an antisense oligonucleotide to enter, gain access to its target mRNA, and exert activity in a
78 y of attachment factors used by the virus to gain access to key cell types involved in pathogenesis a
79 ure suggests that neonatal facilities should gain access to laser technology and laser-trained ophtha
80 model in which core first requires DGAT1 to gain access to LDs, and then LD-localized core interfere
83 group of aminoaldehydes is also required to gain access to lysosomes where their cytotoxic actions a
84 kine receptor CCR7, how other T cell subsets gain access to medullary areas during their normal devel
85 ntracellular antigens have been described to gain access to MHC class II loading after macroautophagy
86 we examine the mechanism by which antibodies gain access to neuronal tissues to control infection.
91 le and undertake diel vertical migrations to gain access to nutrient-rich deeper layers at night and
93 2 and reveal how MDM2-interacting repressors gain access to p53 target promoters and repress transcri
94 t did not label most normal blood vessels or gain access to pancreatic ducts or intestinal smooth mus
95 quiescent CD44(lo)CD62L(hi) T reg cells that gain access to paracrine IL-2 produced in the T cell zon
99 osit that the first shift enables infants to gain access to redundant audiovisual speech cues that en
101 PCNA is not required in vitro for pol eta to gain access to replication complexes at forks stalled by
102 effect terminator read-through, lambdaQ must gain access to RNA polymerase (RNAP) via a promoter-rest
105 spinal hyperexcitability enables A fibers to gain access to specific spinal circuitry, via heterosyna
106 inding mode of SSB, thereby allowing RecQ to gain access to ssDNA and facilitating DNA unwinding.
107 nsights into the mechanism by which proteins gain access to ssDNA bound by SSB, as demonstrated by ex
108 ract with SSB, could use this interaction to gain access to ssDNA by first interacting with the SSB C
109 , generally due to colonizing organisms that gain access to sterile sites via disrupted epithelial ba
110 ansported to IMS-facing membrane leaflets to gain access to tafazzin, identifying a previously unknow
111 al cells, to cross this thin barrier, and to gain access to target cells and tissues, leading to syst
116 lecules can exploit the secondary channel to gain access to the active site and modify the transcript
120 tethered biotin prosthetic group must first gain access to the biotin carboxylase domain and become
130 A major route for peripheral information to gain access to the cerebellum is via ascending climbing
132 Previously, we showed that pneumococci can gain access to the CNS through a nonhematogenous route w
134 s viral penetration of cellular membranes to gain access to the cytoplasm and deliver the genome to t
135 iruses must traverse the nuclear envelope to gain access to the cytoplasm and, ultimately, to exit ce
137 sought to determine how assembled tau seeds gain access to the cytosol and whether this access trigg
138 hagy pathway to defend against microbes that gain access to the cytosol or reside in pathogen-modifie
141 somal DNA lesions, the repair machinery must gain access to the damaged DNA in the context of chromat
143 ion synthesis (TLS), but how TLS polymerases gain access to the DNA template remains poorly understoo
145 zed at P2 but not at P9, E. coli K1 bacteria gain access to the enterocyte surface in the mid-region
148 advantage of endodermal tissue remodeling to gain access to the gonadal mesoderm and are unable to mi
149 D8+ T cell lines have suggested that Mtb Ags gain access to the HLA-I pathway in an alternate vacuola
150 The mechanisms by which Mtb-derived Ags gain access to the HLA-I-processing pathway are incomple
151 suggests that, as in rodents, external cues gain access to the homeostatic control circuits of the h
152 eal a means whereby intracellular Salmonella gain access to the host cell cytosol from within its mem
153 ique intracellular biology that allows it to gain access to the host cell cytosol, Listeria monocytog
154 d pore formation, (ii) innate immune stimuli gain access to the host cytoplasm through the YopBD pore
158 xins have evolved a variety of mechanisms to gain access to the host-cell cytosol and thereby exert v
159 The simulation reveals that water molecules gain access to the internal sites by a transient aqueduc
160 biological tools; however, their ability to gain access to the intracellular environment is limited.
161 ken of the Snieckus hydroborating reagent to gain access to the key trifluoroborate needed for the ma
165 gest a model in which gammaherpesviruses may gain access to the mature B cell compartment by recurren
167 G and that the PAG uses the NRA as a tool to gain access to the motoneurons generating vocalization.
168 sive pneumococcal disease, S. pneumoniae can gain access to the myocardium, kill cardiomyocytes, and
169 on and suggest that HIV-1 subviral particles gain access to the nucleus by interacting directly with
170 xploits the host nuclear import machinery to gain access to the nucleus, where capsid assembly and ge
173 ling indicates that the target peptide might gain access to the PDHK active center through the open b
174 dCII is released and/or phagocytic proteases gain access to the periplasm, and SodCII is degraded.
177 tein DAF to open the tight junction barrier, gain access to the primary receptor CAR, and activate vi
178 d phenotypic characteristics of T cells that gain access to the prostate and induce leukocyte recruit
179 rotation of NADP(+) permits the substrate to gain access to the reactive flavin peroxyanion intermedi
181 ty that imposes constraints on which enzymes gain access to the recombination intermediate, thereby c
182 tRNA shape-mimicry enables the viral IRES to gain access to the ribosome tRNA-binding sites and form
184 AM fungi colonize root epidermal cells to gain access to the root cortex, and this requires the re
185 cked 50S ribosomal subunit, allowing RrmJ to gain access to the substrate nucleotide U2552, and where
186 This suggested that microbiome products that gain access to the systemic circulation, rather than bei
187 corneal epithelial cell-derived exosomes may gain access to the underlying stromal fibroblasts upon d
190 ly are relatively hydrophobic molecules that gain access to their blocking site on the sodium channel
192 but the majority of the vascular plants also gain access to these mineral nutrients through endosymbi
193 arget populations in developing countries to gain access to these potentially life-saving medicines.
194 osine deaminase (AID) that initiates SHM not gain access to these regions, or does AID gain access, b
195 ogical analysis coupled with live imaging to gain access to these relationships in ferrets infected w
196 ivores and fungivores that evolve resistance gain access to these resources and can also gain protect
197 s commonly postulated that plasma cells only gain access to these signals within specialized regulato
198 Yet, circulating antibodies must somehow gain access to these tissues to mediate their antimicrob
199 The olefin is mechanistically critical to gain access to this 14-electron, monovalent Ir intermedi
200 o rapidly access the microcirculation and to gain access to this highly anticoagulant environment.
201 ich microbes bypass host iron restriction to gain access to this metal across the host vacuolar membr
204 pend first on its ability to enter cells and gain access to TLR9 and second on its capacity to form a
205 er evidence, suggests that AID may similarly gain access to transcribed S regions and V exons in vivo
206 sm and binds to the 40S ribosomal subunit to gain access to translating mRNAs, MERS-CoV nsp1 was dist
207 ven basic models to explain how odour inputs gain access to transmodal representations required for n
208 es and other macromolecular therapeutics can gain access to tumor cells via leaky tumor vessels.
209 meable to substrate peptide; water molecules gain access to zinc through a polar, central channel tha
212 in major clades such that some lizard clades gained access to new resources, which in turn led to muc
213 eover, in mice, human IgG from the periphery gained access to relevant areas in the hippocampus and b
216 on conditions during this transformation, we gained access to the natural products as well as two epi
218 The TiO2 nanotubes were believed to have gained access to the nuclear machinery and caused increa
221 tubular reabsorption of macromolecules, that gained access to the tubular lumen on glomerular filtrat
223 ses such as HIV have a daunting challenge in gaining access to a new host predominantly through the p
224 both human and mouse lung adenocarcinomas by gaining access to an endosomal compartment within tumor
225 can be challenging due to the difficulty of gaining access to conventional diagnostic matrices of bl
228 ucing the effective dose of toxin capable of gaining access to glycolipid and glycoprotein receptors
229 use of health information and services: (1) gaining access to health information, (2) navigating in
232 ique "plug-and-play" approach to efficiently gaining access to orphan pathways that may open avenues
233 hat the E1A-12 N terminus prevents PKAc from gaining access to p65 to account for Ser(276) hypophosph
234 ng, aphids inject saliva into plant tissues, gaining access to phloem sap and eliciting (and sometime
236 vectors which, although no longer capable of gaining access to receptors on target cells, may be able
238 hat many SSIs occur as a result of pathogens gaining access to surgical wounds either hematogenously,
239 ractions between PBP 2a and the cell wall in gaining access to the active site in the inhibition proc
240 ency (slope = -0.6 to -1.0), indicating that gaining access to the base lesion provides a substantial
241 esters Daxx in the nucleus, prevents it from gaining access to the cytoplasm, from binding to and act
242 transporter, FepA, as a receptor and, after gaining access to the cytoplasmic membranes of sensitive
243 re more efficient than wild-type bacteria in gaining access to the host cell cytosol and in initiatin
244 e first description of a secreted proteinase gaining access to the inside of a cell and altering intr
245 tablishes a chronic infection in its host by gaining access to the memory B-cell reservoir, where it
246 infections can pose a threat to pregnancy by gaining access to the placenta and fetus, and clinical s
247 ls exiting the intravascular compartment and gaining access to the renal tubular space, we reasoned t
251 h predation to a floral simulation strategy, gaining access to, and visually attracting, a novel reso
252 e receptor-mediated uptake or whether enzyme gains access to brain storage by another route when brai
253 t in retinal disease, mislocalized rod opsin gains access to cAMP signaling, which leads to neuritic
254 e mechanism by which LPS from these bacteria gains access to caspase-11 in the cytosol remains elusiv
256 toplasm from interphase through prophase and gains access to chromosomes only after the nuclear envel
257 e nucleotide excision repair (NER) machinery gains access to damaged chromatinized DNA templates and
260 x1), fail to clear self-DNA, accumulated DNA gains access to intracellular compartments where it driv
261 pus erythematosus, a major route whereby DNA gains access to intracellular TLR9, and thereby activate
262 The data indicate that flecainide rapidly gains access to its binding site when the channel is ope
263 iferase is released from the viral lumen and gains access to its substrates is light emitted and read
264 mechanism by which this virus recognizes and gains access to its target cell is still largely unknown
265 the TCR signal and how the repair machinery gains access to lesions imbedded in stalled RNA polymera
267 tigated the mechanism by which Ty1 integrase gains access to nuclear DNA as a model for how other ret
270 scular mycorrhizal (AM) symbiosis, the plant gains access to phosphate (Pi) and nitrogen delivered by
273 ure reveal how the cytosolic DNA sensor cGAS gains access to the cargo within micronuclei to drive ty
274 ached by blockade by a lipid acyl chain that gains access to the channel cavity through intramembrane
275 Previous data have shown that the virus gains access to the CNS by infecting olfactory sensory n
280 for intrauterine transmission in which ZIKV gains access to the fetal compartment by directly infect
281 Mycobacterium tuberculosis extracellular DNA gains access to the host cell cytosol via the ESX-1 secr
283 human immunodeficiency virus type 1 (HIV-1) gains access to the interior of the target cell, host ce
284 ynamic, providing an explanation of how cAMP gains access to the ligand binding sites that, in the cr
285 infection and persistence proposes that EBV gains access to the memory B cell compartment via GC rea
286 that intestinal epithelium-derived "self-Ag" gains access to the mucosal immune system, leading to Ag
287 ficient mouse chimeras, we demonstrate HSV-1 gains access to the murine brain stem and subsequently b
288 y, cofactor in the incorrect oxidation state gains access to the mutase active site and is not releas
289 The exonuclease travels with pol II and gains access to the nascent RNA after endonucleolytic cl
291 Taken together, these data argue that TgGCN5 gains access to the parasite nucleus by interacting with
293 ng amounts of lipids, we establish that SecA gains access to the SecYEG complex via a lipid-bound int
294 ay be one of the crucial steps by which ZIKV gains access to the site of spermatozoon development and
300 hodopsin was depleted from primary cilia but gained access, without being enriched, with the dual Ax(
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