ライフサイエンスコーパス: galactose-1-phosphate

1 lyzes the conversion of alpha-d-galactose to galactose 1-phosphate.

2 yzing the conversion of alpha-d-galactose to galactose 1-phosphate.

3 dent phosphorylation of alpha-D-galactose to galactose 1-phosphate.

4 ity to hydrolyze inositol monophosphates and galactose 1-phosphate.

5 dine 5'-phosphoryl group from UDP-glucose to galactose 1-phosphate.

6 TP-dependent phosphorylation of galactose to galactose-1-phosphate.

7 UDP-galactose from uridine triphosphate and galactose-1-phosphate.

8 okinase (GALK), phosphorylating galactose to galactose-1-phosphate.

9 D-galactose (2 muM), galactitol (11 muM) and galactose 1-phosphate (0.1 mM), (corresponding to plasma

10 ounterparts, demonstrated elevated levels of galactose 1-phosphate and diminished UDP-gal upon exposu

11 ly reported structures of the Mg(2+)-alpha-d-galactose-1-phosphate-beta-PGM, Mg(2+)-phospho-beta-PGM,

12 requires conversion of GDP-L-galactose to L-galactose 1-phosphate by a previously unidentified enzym

13 IMPase to use both inositol 1-phosphates and galactose 1-phosphate equally as substrates is of consid

14 His residue with GDP-L-galactose, forming L-galactose 1-phosphate for vitamin C synthesis, and regen

15 f the guanylylated enzyme, forming GDP and L-galactose 1-phosphate from GDP-L-galactose and phosphate

16 sitol signaling, we found it also hydrolyzes galactose 1-phosphate (Gal 1-P), an intermediate of gala

17 Therefore, the specific detection of galactose 1-phosphate (Gal 1-P), galactose (Gal), and ur

18 e catalyzes the reaction of UDP-glucose with galactose 1-phosphate (Gal-1-P) to form UDP-galactose an

19 reversible transformation of UDP-glucose and galactose-1-phosphate (Gal-1-P) into UDP-galactose and g

20 In the second reaction, galactose-1-phosphate (gal-1-P) is bound, UDP-galactose

21 sphate (Glc1P), mannose-1-phosphate (Man1P), galactose-1-phosphate (Gal1P), fucose-1-phosphate, gluco

22 Galactose-1-phosphate (galactose-1-P) uridylyltransferas

23 y-dependent growth phenotype and accumulated galactose 1-phosphate, glucose 1-phosphate, and GDP-gluc

24 lyzes the conversion of GDP-L-galactose to L-galactose 1-phosphate in a reaction that consumes inorga

25 lyzes the conversion of GDP-L-galactose to L-galactose 1-phosphate in the first committed step of the

26 uridine 5'-diphosphate glucose (UDPGlc) and galactose-1-phosphate into uridine 5'-diphosphate galact

27 a) has similarity to IMP and can hydrolyze l-galactose 1-phosphate (l-Gal 1-P), suggesting that this

28 Six interconvertible 'core intermediates', galactose 1-phosphate <--> UDP-galactose <--> UDP-glucos

29 alactose and its metabolites, galactitol and galactose 1-phosphate, on oocyte quality as well as embr

30 e catalyzes the reaction of UDP-glucose with galactose 1-phosphate to form UDP-galactose and glucose

31 polysaccharide biosynthesis by transferring galactose-1-phosphate to a lipid carrier.

32 ate uridyltransferase (GALT), which converts galactose-1-phosphate + UDP-glucose to glucose-1-phospha

33 way for galactose metabolism (galactokinase, galactose-1-phosphate-uridyl transferase and UDP glucose

34 id 188 (Q188R) ablates the function of human galactose-1-phosphate uridyltransferase (GALT) and is th

35 on isoelectric focusing and 50% reduction in galactose-1-phosphate uridyltransferase (GALT) enzyme ac

36 Deficiency in the galactose-1-phosphate uridyltransferase (GALT) enzyme re

37 In humans, the absence of galactose-1-phosphate uridyltransferase (GALT) leads to

38 Galactosemia I results from loss of galactose-1-phosphate uridyltransferase (GALT), which co

39 od cell (RBC) UDPgalactose concentrations in galactose-1-phosphate uridyltransferase-deficient patien

40 epared enzymatically using galactokinase and galactose-1-phosphate uridyltransferase.

41 lethal disease caused by the dysfunction of galactose 1-phosphate uridylyltransferase (GALT).

42 Galactose-1-phosphate uridylyltransferase (GALT) acts by

43 Galactose-1-phosphate uridylyltransferase (GalT) catalyz

44 Galactose-1-phosphate uridylyltransferase (GalT) catalyz

45 The active site of galactose-1-phosphate uridylyltransferase (GALT) include

46 Impairment of the human enzyme galactose-1-phosphate uridylyltransferase (GALT) results

47 of Fhit-related hydrolases, and a branch of galactose-1-phosphate uridylyltransferase (GalT)-related

48 tion that results from partial impairment of galactose-1-phosphate uridylyltransferase (GALT).

49 Impairment of the human enzyme galactose-1-phosphate uridylyltransferase (hGALT) result

50 Galactose-1-phosphate uridylyltransferase catalyzes the

51 Galactose-1-phosphate uridylyltransferase catalyzes the

52 y and contrast between the roles of GALE and galactose-1-phosphate uridylyltransferase in galactose m

53 Galactose-1-phosphate uridylyltransferase plays a key ro

54 pplied a yeast coexpression system for human galactose-1-phosphate uridylyltransferase, a dimeric enz

55 second enzyme of the Leloir pathway, namely galactose-1-phosphate uridylyltransferase, alternate for

56 eoside monophosphate transferases, including galactose-1-phosphate uridylyltransferase, diadenosine t

57 ed by the chain-fold similarities of Fhit to galactose-1-phosphate uridylyltransferase, which functio

58 The chain fold of Fhit is similar to that of galactose-1-phosphate uridylyltransferase, which functio

59 strate recognition and binding in the native galactose-1-phosphate uridylyltransferase.

60 d by a naturally occurring mutation in human galactose-1-phosphate uridylyltransferase.

61 otif that is reminiscent of the HPH motif in galactose-1-phosphate uridylyltransferases, in which the