ライフサイエンスコーパス: galactosyl ceramide

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1 osphingolipid, or a synthetic agonist, alpha-galactosyl ceramide.

2 aired following in vivo challenge with alpha-galactosyl ceramide.

3 of a precursor lipid, galactosyl-(alpha1-2)-galactosyl ceramide.

4 bes a short and efficient synthesis of alpha-galactosyl ceramide.

5 ns (MLR), anti-CD3, and the glycolipid alpha-galactosyl ceramide.

6 using the previously cloned cDNA encoding a galactosyl ceramide 3-O-sulfotransferase, which we term

7 Galactosyl ceramide, a glycosphingolipid, has been postu

8 the CD1d molecule to bind and present alpha-galactosyl ceramide after lysosomal processing of a prec

9 Keratinocytes loaded with alpha-galactosyl ceramide (alpha-GalCer) could stimulate IFN-g

10 They react to the glycolipid alpha-galactosyl ceramide (alpha-GalCer) presented by CD1d, an

11 her species can present the glycolipid alpha-galactosyl ceramide (alpha-GalCer) to mouse natural kill

12 ll responses to the glycolipid antigen alpha-galactosyl ceramide (alpha-GalCer) were dampened by prio

13 ogs of the well known NKT cell agonist alpha-galactosyl ceramide (alpha-GalCer), bacterial glycolipid

14 aded with a synthetic NKT cell ligand, alpha-galactosyl-ceramide (alpha-GalCer; KRN-7000) in five pat

15 ion with the NKT cell-specific agonist alpha-galactosyl ceramide (alphaGC), Sh2d1a-/- splenocytes did

16 in response to the model iNKT cell Ag alpha-galactosyl ceramide and expressed lower amounts of the T

17 ted with the NKT cell-specific agonist alpha-galactosyl ceramide and its analog PBS57.

18 simple strategy for the synthesis of beta-C-galactosyl ceramide and its new aza-variant analogue is

19 le for assembly or the ability to bind alpha-galactosyl ceramide and to present it to human NKT cells

20 into oligomers that were capable of binding galactosyl-ceramide and G(M1) gangliosides.

21 Cell surface expression was detected for galactosyl ceramide but not for CC-chemokine receptor 5,

22 uding NKT cells not reactive with CD1d-alpha-galactosyl ceramide complexes.

23 The preparation of the glycosphingolipid galactosyl ceramide from an orthogonally protected five-

24 ugh both Gal3ST-2 and Gal3ST-3 do not act on galactosyl ceramide, Gal3ST-3 is only moderately more ho

25 IV-1 receptor proteins CD4, CCR5, CXCR4, and galactosyl ceramide (GalCer).

26 Alpha-galactosyl ceramide has been identified to be a potent s

27 By contrast, alpha-galactosyl ceramide induced cytokine secretion is depend

28 ion factor 21 and GATA3 expression and alpha-galactosyl ceramide-induced cytokine production in vivo.

29 1) and recognize lipid antigens (e.g., alpha-galactosyl ceramide) presented by nonpolymorphic CD1 mol

30 levels of IL-4 following TCR ligation, alpha-galactosyl ceramide-stimulated NKT cells from the livers

31 ctin binds sulfated proteoglycan, 3-sulfated galactosyl ceramide (sulfatide), and heparin.

32 er T (NKT) cells mobilizing glycolipid alpha-galactosyl ceramide, used to mature splenic DCs, served

33 A beta-C-galactosyl ceramide was synthesized in a stereoselective

34 In vivo stimulation of iNKT cells by alpha-galactosyl-ceramide was effective in both preventing and

35 nistration of concanavalin A (ConA) or alpha-galactosyl-ceramide, which induce liver inflammation and

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