ライフサイエンスコーパス: gallinaceum

1 T2, in the avian malaria parasite Plasmodium gallinaceum.

2 nism when invaded by either P. berghei or P. gallinaceum.

3 n, PgCHT2, a putative second chitinase of P. gallinaceum.

4 d, as yet unidentified, chitinase gene of P. gallinaceum.

5 identified in the avian malaria parasite P. gallinaceum.

6 ty of Aedes aegypti mosquitoes by Plasmodium gallinaceum.

7 th of the avian malaria parasite, Plasmodium gallinaceum.

8 th of the avian malaria parasite, Plasmodium gallinaceum.

9 enhanced after the infection with Plasmodium gallinaceum.

10 re it is shown that the protozoan Plasmodium gallinaceum, a close relative of the human malaria paras

11 Plasmodium gallinaceum ADA does not use MTA as a substrate, is not

12 HT1 of the avian malaria parasite Plasmodium gallinaceum and a paralog of PfCHT1 of the human malaria

13 ase of the avian malaria parasite Plasmodium gallinaceum and cloned the gene, PgCHT1, encoding it.

14 The polygenic nature of susceptibility to P. gallinaceum and epistasis are important factors for sign

15 XA activated gametogenesis of Plasmodium gallinaceum and P. falciparum in vitro at concentrations

16 asite combinations, Aedes aegypti-Plasmodium gallinaceum, Anopheles stephensi-Plasmodium berghei, and

17 tes of the avian malaria parasite Plasmodium gallinaceum appear to secrete products of two chitinase

18 t chitinases of Plasmodium falciparum and P. gallinaceum are concentrated at the apical end of ookine

19 inst a synthetic peptide derived from the P. gallinaceum chitinase active site, PgCHT1, even though M

20 significantly reduced the infectivity of P. gallinaceum for A. aegypti.

21 ry promising activity in both our Plasmodium gallinaceum (>80%) and Plasmodium falciparum (>40%) mode

22 ays to assess the effect of these MAbs on P. gallinaceum infectivity for Aedes aegypti mosquitoes, th

23 P. gallinaceum is a relevant animal model that facilitates

24 The chitinase PgCHT1 of P. gallinaceum is present within ookinete micronemes and su

25 erythrocytes, whereas avian host Plasmodium gallinaceum microgametes bind chicken but not human eryt

26 These data suggested that in Plasmodium gallinaceum morphological development of zygote to ookin

27 ces reveals four distinct groupings, with P. gallinaceum most closely related to the human malaria Pl

28 eeding assays, MAb 1C3 markedly inhibited P. gallinaceum oocyst development in mosquito midguts.

29 by benzamidine affinity column of Plasmodium gallinaceum ookinete axenic culture supernatant demonstr

30 rasite-secreted proteins found in Plasmodium gallinaceum ookinete culture supernatants.

31 band as detected by Western immunoblot of P. gallinaceum ookinete supernatants.

32 These data suggest that the P. gallinaceum ookinete uses products of more than one chit

33 hibited two chromatographically separable P. gallinaceum ookinete-produced chitinase activities with

34 Plasmodium gallinaceum ookinetes injected into the fly developed in

35 ell types, and have proposed that Plasmodium gallinaceum ookinetes prefers a specific cell type (Ross

36 eacts with a discrete apical structure of P. gallinaceum ookinetes.

37 from endochitinase activities secreted by P. gallinaceum ookinetes.

38 PgPM4 and PgCHT2 (the P. gallinaceum ortholog of P. falciparum chitinase PfCHT1)

39 CSP from P. falciparum, P. gallinaceum, P. knowlesi, and P. yoelii species represen

40 y significantly reduced P. falciparum and P. gallinaceum parasite transmission to mosquitoes.

41 chitinases of P. berghei, P. yoelii, and P. gallinaceum (PgCHT1).

42 The P. gallinaceum protein has the characteristics of CS protei

43 The P. gallinaceum repeat region consists of 9-amino acid repea

44 edes aegypti and malaria parasite Plasmodium gallinaceum system.

45 In these mosquitoes infected with P. gallinaceum, the number of oocysts was dramatically redu

46 ythrocytic stage (98% of activity against P. gallinaceum), thus suggesting that it may be possible to

47 significantly reduced the infectivity of P. gallinaceum to Aedes aegypti and P. falciparum to Anophe

48 orescence localization studies in Plasmodium gallinaceum using specific antisera showed that all thre

49 e CS gene from the avian parasite Plasmodium gallinaceum was characterized to compare these functiona

50 egypti, to the malarial parasite, Plasmodium gallinaceum, was investigated using an integrated, targe

51 ensi-Plasmodium berghei, and A. stephensi-P. gallinaceum, were directly compared by using enzymatic m

52 demonstrate that the ookinetes of Plasmodium gallinaceum, which is related closely to the human malar

53 B5, and 4B6-were identified that bound to P. gallinaceum zygotes and ookinetes in diverse patterns in