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1 ome 15, encodes the DNA polymerase gamma(Pol gamma).
2 ms would be unstable if not for variation in gamma.
3 was reversed by therapeutic blockade of IFN-gamma.
4 recognition repeats termed alpha, beta, and gamma.
5 in lungs including TNF, IL-6, IL-10, and IFN-gamma.
6 ed with mice deficient in all sources of IFN-gamma.
7 t when the human host cell is exposed to IFN-gamma.
8 IRF8 that was further induced by interferon-gamma.
9 inhibit STAT1 phosphorylation induced by IFN-gamma.
10 eukin-4 and reduced production of interferon-gamma.
11 tralized interferon (IFN)-alpha, but not IFN-gamma.
13 At 6 hpi, Pol II increased on gamma(1) and gamma(2) genes while Pol II pausing remained prominent o
15 It was noted that these 1:1 alpha/Sulfono-gamma-AA peptides were completely resistant to proteolyt
17 odel application, the right-handed d-sulfono-gamma-AApeptides reveal much-enhanced binding affinity c
19 the digestion of PNNs induces a decrease in gamma activity, an oscillation dependent on PV+ cells, i
22 tional link between selective processing and gamma-activity.SIGNIFICANCE STATEMENT The ability to foc
23 Previous studies have implicated a role for gamma-adducin (ADD3), a cytoskeletal protein encoded by
24 (peroxisome proliferator-activated receptor gamma) agonist that stimulates mitochondrial activity, a
26 granular supports such as carbon materials, gamma-Al(2)O(3), and zeolite, which is vital to their pr
30 that release the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) at non-image-forming brai
31 -fat milk and regular-fat cheese enriched in gamma-aminobutyric acid (GABA) influences daytime ambula
32 xylase enzyme GAD67, a critical actor of the gamma-aminobutyric acid (GABA) metabolism as it catalyse
33 tion of the metabotropic GABA(B) receptor by gamma-aminobutyric acid (GABA) results in prolonged inhi
34 ors (HA) exhibited a significant increase in gamma-aminobutyric acid (GABA) transmission compared wit
35 o find the relative quantity of glutamate to gamma-aminobutyric acid (GABA), DA, and glutamate neuron
36 lase 2 but not the parvalbumin subset of SNr gamma-aminobutyric acid (GABA)-releasing (GABAergic) neu
38 drugs that inhibit alpha5 subunit-containing gamma-aminobutyric acid type A receptor function improve
39 ed that inhibiting alpha5 subunit-containing gamma-aminobutyric acid type A receptors would improve c
44 ory inflammatory cytokines, for example, IFN-gamma and IL-12, in CCR2i- versus vehicle-treated mice.
45 on of T cell-derived IL-10 increased the IFN-gamma and IL-17A response to HDM, reducing IL-13 levels
46 that this depends on PLP-CD8 elaborating IFN-gamma and perforin in a coordinated suppression program
47 associated with feedforward processing than gamma and pose limits on the proposed role of gamma as a
48 scence-based assay was developed against IFN-gamma and provided an optimized, physiologically relevan
50 n-induced microstructure bands of austenite (gamma) and martensite (alpha' ) phases on the partitioni
52 materials to produce a range of multifaceted gamma-aryl tertiary alkylamines and can be rendered enan
54 associated with increases in spiking and in gamma-band (40 to 90 Hz) power/connectivity that fed for
55 understand the neural mechanisms underlying gamma-band ASSR network abnormalities in schizophrenia.
56 e) and 16 unexposed donors, using interferon-gamma-based assays with peptides spanning SARS-CoV-2 exc
58 ncludes parameters for Signal Amplification (gamma), Binding affinity (K(d)), Receptor activation Eff
61 mic acid, hydroxymethylfurfural, lipids, and gamma-butyrolactone also contributed to score and sensor
64 ages, most genes belong to an avian-specific gamma-c clade, within which sequences cluster by species
65 elling experiments, which indicated that the gamma-C(sp(3) )-H bond cleavage is the rate-limiting ste
66 octadecanedioate and vitamin E metabolites (gamma-CEHC and gamma-CEHC glucuronide); MR analysis show
67 te and vitamin E metabolites (gamma-CEHC and gamma-CEHC glucuronide); MR analysis showed that genetic
68 the regions between CDR2 and CDR3 of the TCR gamma chain and modulated by the affinity of the CDR3 re
71 those of other sauropsid species in a gamma (gamma) clade that predates the divergence of different a
72 ine influenza viruses isolated in 2009-2016, gamma-clade viruses had less stable HA proteins (activat
73 Peroxisome proliferator activated receptor gamma coactivator (PGC)-1alpha, has been proposed as a m
74 (peroxisome proliferator-activated receptor-gamma coactivator 1), a Parkin downstream target that ca
75 e peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) is a transcriptio
76 t peroxisome proliferator-activated receptor gamma coactivator 1-alpha and oxidative phosphorylation
77 isome proliferator-activated receptor (PPAR) gamma-coactivator 1alpha], PPARalpha, and catalase as ke
78 wakefulness was not restored, the functional gamma connectivity remained reduced, but there was a sig
81 The methodology provides a short route to gamma-cyanoesters that can be useful synthetic intermedi
82 ter-soluble azobenzene and alpha-, beta-, or gamma-cyclodextrins, have been proposed as a model to st
83 ions of curcumin/HP-beta-CyD and curcumin/HP-gamma-CyD were yielded uniform fiber morphology with ~20
90 lating Il-18bp is induced in response to Ifn-gamma during CpG-induced macrophage activation syndrome
92 carriers that recruit GGA (Golgi-localized, gamma-ear-containing, ARF-binding protein), clathrin ada
94 y the presence of concomitant and dominating gamma emitters, primarily (137)Cs, which results in incr
95 ever, the detection of minute amounts of the gamma-emitting radiosilver isotopes is often thwarted by
96 idues in the cytosolic portions of beta- and gamma-ENaC subunits as being important for PIP(2)-ENaC i
97 rements for IFN-gamma production and how IFN-gamma enhances local immune responses to prevent Bp-medi
99 rophage) M1-like polarization and interferon-gamma-expressing T-helper type 1 (Th1) cells but increas
100 ed leptin sensitivity via reduced interferon-gamma expression and induced adipose leptin expression v
101 There was also a protective effect of higher gamma' fibrinogen levels on cardioembolic and large arte
102 n of ischaemic stroke, while factor VIII and gamma' fibrinogen require further population-based studi
104 ipsilesional M1 to contralesional M1 within gamma frequencies during motor preparation for hand open
105 These interactions occurred in beta and gamma frequency bands depending on the area contributing
106 and 1440 mg) on NMDAR engagement measured by gamma-frequency band auditory steady-state response (40
107 is important for synchronization across the gamma-frequency range, the role of distinct interneurona
108 r with those of other sauropsid species in a gamma (gamma) clade that predates the divergence of diff
110 naling pathway from HRI to ATF4 to BCL11A to gamma-globin and illustrate potential limits of murine m
111 actor 4 (ATF4) as a novel regulator of fetal gamma-globin gene expression in human cells by repressin
112 llele copy, P = 0.046-0.002), including five gamma-glutamyl amino acids, beta-citryl-glutamate, N-ace
113 lele in HUVECs, including impairments of the gamma-glutamyl cycle and methylglyoxal detoxification.
115 ohort, adults with Pi*MZ had lower levels of gamma-glutamyl transferase in serum and lower LSMs than
116 ecular-weight thiol-containing tripeptide (l-gamma-glutamyl-l-cysteinyl-glycine) that can function as
117 common grade 3-4 adverse events were raised gamma-glutamyltransferase (13 [16%] of 80 patients; coho
120 This approach yielded the first structure of gamma-herpesviral core NEC, namely the 1.56 angstrom str
121 stein-Barr virus (EBV) is a ubiquitous human gamma-herpesvirus that establishes life-long infection a
122 ted CAR-T cell activation through interferon gamma (IFN-gamma) production and CD107a membrane accumul
123 find that T cell infiltration and interferon-gamma (IFN-gamma) signaling signatures correspond most h
124 monstrate a role for the cytokine interferon-gamma (IFNgamma) and the enzyme transglutaminase 2 (TG2)
127 blast expansion and cytokine production (IFN-gamma, IL-2, and TNF), with the highest median magnitude
129 te T-bet and coexpress IL-17, IL-22, and IFN-gamma in a STAT3- and retinoic acid-dependent manner.
130 learance, we found that increased plasma IFN-gamma in early clinical sepsis was associated with the l
131 37 cells, enhanced induced production of IFN-gamma in human PBMC culture, and increased survival of i
132 gher (p < 0.01) concentrations of interferon-gamma in plasma of low responders compared to high respo
136 ein, as evidenced by an observed hd-anti-IFN-gamma-induced increase in the specific binding of IFN-ga
139 pleckstrin homology (PH) domains 2 (ADAP2), gamma-interferon-inducible lysosome/endosome-localized t
140 zing) and CD4+ T-cell (expressing interferon-gamma, interleukin-2, and CD40 ligand) responses were ev
141 has been developed, wherein a beta amine and gamma iodide are incorporated onto an aliphatic alcohol
144 2 receptor activation prevents and mitigates gamma-irradiation-induced colonic mucosal barrier dysfun
146 ng in isolated human HDL either by synthetic gamma-ketoalkenal phospholipids or by oxPLs generated du
147 1960, and Feb 1, 2020, reporting the use of gamma knife radiosurgery as primary treatment for uveal
148 the efficacy, outcomes, and complications of gamma knife radiosurgery for uveal melanomas and metasta
151 at ERR (estrogen-related receptor) alpha and gamma, known transcriptional regulators of postnatal mit
153 myrocin G (4) to the corresponding 5-hydroxy-gamma-lactone isomer myrocin C (1) are also detailed.
159 selected Mertensia species were analyzed for gamma-linolenic acid-rich oils and minor functional comp
160 en category is encoded via broadband and sub-gamma (<30 Hz) power variations, while the attended cate
161 ls, cysteine metabolism by the cystathionine gamma lyase (CSE), generates hydrogen sulfide-related su
162 lfide (H(2)S) by inhibition of cystathionine gamma-lyase (CSE) increases sFlt-1 and soluble endoglin
163 the canonical definition of temperature and Gamma(mag); and iii) possibility of performing adiabatic
165 RNA decay pathways, the PABPN1- and PAPalpha/gamma-mediated RNA decay (PPD) pathway and an ARS2-media
167 ated by the dynamic expression in remodeling gamma-neurons, we focus here on the role of actin elonga
168 DNA copies, and surges in granzyme B and IFN-gamma occurred within the early hours after reactivation
170 rthermore, the combination of MTP-PE and IFN-gamma on AML blasts generated an inflammatory cytokine p
173 r GSK3beta inhibition reverses both abnormal gamma oscillations and behavioral deficits with high cor
175 rogression whereas the induction of cortical gamma oscillations can reduce amyloid load and improve c
180 of ring conformation, while a novel residue, gamma-oxo-delta-azaproline, features rapid amide isomeri
182 major phospholipase in mitochondria, iPLA(2)gamma (patatin-like phospholipase domain containing 8 (P
184 ithelium with 5-amino salicylic acid, a PPAR-gamma (peroxisome proliferator-activated receptor gamma)
186 e preceded by enhanced STN spike-to-cortical gamma phase coupling, indicating a role in motor prepara
190 ignaling also induced an anergic T-bet(-)IFN-gamma(-) phenotype in CD8(+) T cells and was equally sup
191 system (the TriPPPro approach), in which the gamma-phosphate is covalently modified by two different
192 T calculations show that a degeneracy at the Gamma point of the energy bands of the high-temperature
196 ical response, psychotomimetic symptoms, and gamma power changes in 34 individuals (ages 18-65) with
197 ons partially rescued the elevated broadband gamma power elicited by subanesthetic doses of ketamine.
198 minated V4 theta, it had little effect on V4 gamma power except for delaying its emergence by >100 ms
202 bited reduced basal alpha power and enhanced gamma power, and these rats showed enhanced locomotor ac
204 ion of peroxisome protein activator receptor gamma (PPARgamma), a nuclear receptor involved in inflam
205 pes, induced HSV-specific polyfunctional IFN-gamma-producing CD107(ab+) CD4(+) T cells associated wit
207 It will be worth investigating whether IFN-gamma-producing ILCs also improve endometrial resistance
208 on by them, with mycobacterium-specific, IFN-gamma-producing, purely adaptive CD8(+) alphabeta T, and
209 rovide insight into the requirements for IFN-gamma production and how IFN-gamma enhances local immune
211 sequencing, we found that in GA lesions IFN-gamma production by CD4(+) T cells is upregulated and is
212 , and Vdelta2(+) gammadelta T cells) and IFN-gamma production by them, with mycobacterium-specific, I
213 (antigen-specific antibody responses and IFN-gamma production) and biodistribution (antigen and adjuv
214 cellular responses, as characterized by IFN-gamma production, upon re-stimulation with SARS-CoV-2 pe
218 ell activation through interferon gamma (IFN-gamma) production and CD107a membrane accumulation by fl
219 utilizes accessible carbamate esters bearing gamma-propargylic C-H bonds and furnishes versatile prod
220 alizing antibodies against TNF-alpha and IFN-gamma protected mice from mortality during SARS-CoV-2 in
221 oflexi, and classes Anaerolineae, Delta- and Gamma- Proteobacteria than the deeper sections, indicati
224 ient olefins for the generation of unnatural gamma-quaternary amino acids and other valuable syntheti
226 nt of resistance of E. dermatitidis to acute gamma-radiation exposure and the major mechanisms it use
232 testing identified the same T-cell receptor gamma rearrangement present in the gastric biopsies.
233 the loss of virus-infected cells through Fc gamma receptor (FcgammaR)-mediated effector functions, w
234 zation of its putative protein substrate IFN-gamma receptor 1 (IFNGR1) at the protein level in TNBC.
235 -2 had significantly more C1q binding and Fc gamma receptor activation, a surrogate for ADCC function
238 monoclonal antibodies require binding to Fc gamma receptors (FcgammaRs) for full effect and increasi
239 By comparison, peripheral blood interferon gamma release assays in the same cohort achieved a PPV o
247 visual signals should be transferred through gamma-rhythmic bursts of information, resulting in a mod
250 Furthermore, knockout of IFITM3 reduces gamma-secretase activity and the formation of amyloid pl
251 M3 in neurons and astrocytes, which binds to gamma-secretase and upregulates its activity, thereby in
252 mature form and impairs the integrity of the gamma-secretase complex as well as its catalytic activit
253 ptors, their ligands (Jagged 1-2, DLL1,3,4), gamma-secretase complex proteins (Presenilin 1, Nicastri
255 ne tissues from mice given injections of the gamma-secretase inhibitor dibenzazepine, and mice with i
256 nyl]-S-phenylglucine t-butyl ester (DAPT), a gamma-secretase inhibitor, which inhibits Notch signalin
258 These findings reveal a mechanism in which gamma-secretase is modulated by neuroinflammation via IF
259 e disclose three structurally differentiated gamma-secretase modulators (GSMs) based on an oxadiazine
260 ld type APH-1B or the APH-1B T27I variant on gamma-secretase processing of human APP, the murine Notc
261 esenilin 1 (PS1) is the catalytic subunit of gamma-secretase, an enzyme complex responsible for the m
263 edian frequency of RSV-F-specific interferon gamma-secreting T-cells after a ChAd155-RSV high dose wa
264 SG3 autoantibodies stimulated DSG3-CAART IFN-gamma secretion and homotypic clustering, consistent wit
266 re dependent on IL-18 and IL-12, whereas IFN-gamma secretion was restricted by high concentrations of
267 ed products in up to 91 % yield, >98:2 alpha:gamma selectivity, >98:2 Z:E selectivity, and >99:1 enan
269 unication between the IFN-alpha/beta and IFN-gamma signaling pathways to optimize antiviral IFN-gamma
271 and ultimately requires tumor-intrinsic IFN-gamma signaling, via a mechanism that is distinct from o
272 cell infiltration and interferon-gamma (IFN-gamma) signaling signatures correspond most highly with
273 l as TNF-alpha, IL-6, or IL-17A, but not IFN-gamma, similarly induced sHLH in SIRPalpha(-/-) mice but
280 Conditional kidney tubule-specific ENaC gamma-subunit knockout mice displayed decreased claudin-
283 (HSs) underwent iTBS during gamma-tACS (iTBS-gamma tACS) and during sham-tACS (iTBS-sham tACS) in two
284 healthy subjects (HSs) underwent iTBS during gamma-tACS (iTBS-gamma tACS) and during sham-tACS (iTBS-
285 a non-hydrolyzable ATP analog, adenosine 5'-(gamma-thio)-triphosphate (ATPgammaS) added intravenously
286 uced increase in the specific binding of IFN-gamma to its receptor in U937 cells, enhanced induced pr
291 ly by correctly localising the MT nucleator, gamma-Tubulin Ring Complex (gamma-TuRC), within the cell
292 metric architecture, the gamma-TuRC arranges gamma-tubulins into a helical geometry poised to nucleat
293 Despite its asymmetric architecture, the gamma-TuRC arranges gamma-tubulins into a helical geomet
294 mma-TuRC) has been identified, precisely how gamma-TuRC nucleates a MT remains poorly understood.
295 associated protein complex, Augmin, recruits gamma-TuRC to pre-existing spindle MTs, amplifying their
296 he MT nucleator, gamma-tubulin ring complex (gamma-TuRC) has been identified, precisely how gamma-TuR
299 r peroxisome proliferator-activated receptor gamma was associated with accumulation of lipid vacuoles
300 We report the first example of a statistical gamma work distribution applied to single molecule pulli