ライフサイエンスコーパス: gamma delta T cell

1 t demyelination in nude mice was mediated by gamma delta T cells.

2 and is required for stimulation of V(delta)1 gamma delta T cells.

3 robial lipid antigens to both alpha beta and gamma delta T cells.

4 a mechanism of Ig-like ligand recognition of gamma delta T cells.

5 ct inhibition of naive alpha beta T cells by gamma delta T cells.

6 al manner, by a subset of tumor-infiltrating gamma delta T cells.

7 t in the liver and around 20% of the splenic gamma delta T cells.

8 broadly recognized by intestinal epithelial gamma delta T cells.

9 human gamma delta T cells but not in resting gamma delta T cells.

10 istically to augment IFN-gamma production by gamma delta T cells.

11 ognition of such prenyl pyrophosphate Ags by gamma delta T cells.

12 nduced by mycobacterial Ags were detected in gamma delta T cells.

13 ation likewise defines, at the clonal level, gamma delta T cells.

14 re, vaccinia induced antigen-specific memory gamma delta T cells.

15 od about the function of tissue-infiltrating gamma delta T cells.

16 ntial level of self-induced apoptosis of the gamma delta T cells.

17 ly do not promote the efficient expansion of gamma delta-T cells.

18 lymphocytes such as NK cells, NKT cells, and gamma-delta T cells.

19 re CD4(+), 43.3% were CD8(+), and 12.9% were gamma-delta T cells.

20 onal Foxp3(+) induced regulatory T cell-like gamma/delta T cells.

21 ime in evolution as classical alpha/beta and gamma/delta T cells.

22 the inflammatory response in the absence of gamma/delta T cells.

23 lta 1 TCRs, the TCR expressed by most tissue gamma/delta T cells.

24 earance of L. monocytogenes was dependent on gamma/delta T cells.

25 ding of the soluble platelet molecule to the gamma/delta T cells.

26 ect on Th1 cells or interleukin-17-producing gamma/delta T cells.

27 by mitogen activated bovine peripheral blood gamma/delta T cells.

28 g mature CD3+ T cells and a complete lack of gamma/delta T cells.

29 ty of cells contained in these cultures were gamma/delta T cells.

30 ot B6 controls, suggesting a contribution of gamma(delta) T cells.

31 d B cells, NKT cells (CD1 knockout mice), or gamma(delta) T cells.

32 lls, both CD4+ (150%) and CD8+ (60%), and of gamma/delta T cells (70%) present within the intestinal

33 Depletion of gamma delta+ T cells abrogated myocarditis susceptibilit

34 Gamma delta T cells accumulate at epithelial barriers an

35 gamma delta T cells accumulate during Plasmodium infecti

36 have addressed the mechanism whereby murine gamma delta T cells acquire the capacity to differential

37 is most likely mediated through the type of gamma delta T cells activated during CVB3 infection, and

38 ols, indicating that BCG vaccination induced gamma delta T cell activation associated with enhanced s

39 dual function may serve to prevent erroneous gamma delta T cell activation by cross-reactive cell sur

40 ns, this finding suggests a new way in which gamma delta T cell Ag recognition can be regulated.

41 The role of gamma(delta) T cells against E. cuniculi infection was f

42 s robust memory effector CD4(+), CD8(+), and gamma delta T cells, all of which are relevant for prote

43 L-12; however, unlike Th2 cells, IL-4-primed gamma delta T cells also expressed this receptor, even i

44 mice confirmed that mice lacking functional gamma delta T cells also fail to develop ACAID.

45 to undergo acute homeostatic proliferation, gamma delta T cells also required their own depletion.

46 atural killer cells and selective defects in gamma delta T cells and dendritic antigen-presenting cel

47 nduced a rapid and extensive accumulation of gamma delta T cells and macrophages in the brain.

48 Coadministration of activated gamma delta T cells and naive alpha beta T cells at the

49 reciprocal stimulatory interactions between gamma delta T cells and other T cell subsets.

50 Well-known members of this group include the gamma-delta T cell and the Natural Killer T cell.

51 lipopolysaccharide, a setting in which liver gamma-delta T cells and invariant natural killer T cells

52 els of IL-22 transcripts could be induced in gamma/delta T cells and alpha/beta T cells.

53 Bovine gamma/delta T cells and neutrophils roll on 24 h cytokin

54 /delta T cells are the main tissue subset of gamma/delta T cells and they are known to recognize CD1c

55 Moreover, ES-62 modulated the migration of gamma/delta T cells and this was reflected by direct sup

56 nd macrophages), early induced (NK cells and gamma delta T cells), and adaptive immune responses (alp

57 , the response was strongest with V gamma 1+ gamma delta T cells, and in comparison with related poly

58 uced Fas and Fas ligand (FasL) expression by gamma delta T cells, and in the presence of metalloprote

59 ulates CD8 alpha beta and V(gamma)9V(delta)2 gamma delta T cells, and is required for stimulation of

60 nd T-regulatory cells, natural killer cells, gamma delta T cells, and other accessory cells.

61 neutrophils directly, it was chemotactic for gamma/delta T cells, and CCL8-responsive gamma/delta T c

62 CD4 T cells, gamma/delta T cells, and IL-18 were not critical.

63 ells were also predominantly CD8(+) and bore gamma delta T-cell antigen receptors.

64 teractions reduced the level of Mtb-mediated gamma delta T cell apoptosis by 75 to 80%.

65 ring the response of the V gamma 6/V delta 1 gamma delta T cells appears to be neither foreign nor or

66 In circulating gamma delta T cells, approximately 80% expressed CD94, a

67 ively, these data demonstrate that activated gamma delta T cells are capable of modulating the abilit

68 TCR gamma delta T cells are considered important in the rapi

69 Alpha beta and gamma delta T cells are distinguished by the clonotypic

70 ease multiple sclerosis, we demonstrate that gamma delta T cells are important regulators of CNS infl

71 these findings demonstrate that Mtb-reactive gamma delta T cells are more susceptible to AICD and tha

72 Thus, gamma delta T cells are needed for sustaining at least o

73 sides the TCR, no other components unique to gamma delta T cells are needed.

74 es results in similar antibody isotypes when gamma delta T cells are present, suggesting that vector

75 Gamma delta T cells are the predominant T cell populatio

76 is indicates that distinct subpopulations of gamma delta+ T cells are activated after CVB3 infection

77 it is demonstrated that apoptosis-resistant gamma delta-T cells are capable of mediating significant

78 ations of induced resistance to apoptosis in gamma delta-T cells are considered and discussed because

79 It is first established that human gamma delta-T cells are exquisitely sensitive to apoptos

80 t a detectable but greatly reduced rate, but gamma/delta T cells are completely absent.

81 We conclude that bovine gamma/delta T cells are important sources of IL-22 and s

82 While gamma/delta T cells are involved in host defense and imm

83 ly to naive CD8 alpha/beta T cells, CD44(lo) gamma/delta T cells are poorly cycling in vivo in the st

84 CD8(+) alpha/beta T cells, Ly-6C(+)CD44(hi) gamma/delta T cells are sparse in the thymus but largely

85 As Vdelta1+ gamma/delta T cells are the main tissue subset of gamma/

86 ses (150 x 106) and was a unique property of gamma delta T cells, as activated alpha beta T cells wer

87 udies were conducted using ex vivo-activated gamma delta T cells because this was a more clinically r

88 To better apprehend gamma/delta T cell biological functions in the periphery

89 stages that generate not only alpha beta and gamma delta T cells but can produce dendritic cells and

90 in IL-15-stimulated and Ag-stimulated human gamma delta T cells but not in resting gamma delta T cel

91 advances continue to support the notion that gamma delta T cells can perform specialized functions re

92 These results show, for the first time, that gamma delta T cells can substitute for alpha beta T cell

93 We show that CD1-restricted gamma/delta T cells can mediate the maturation of DCs.

94 n normal mice belong to a distinct subset of gamma delta T cells characterized by low expression of T

95 The gamma delta T cell clone LBK5 recognizes the MHC molecul

96 A panel of Borrelia-reactive gamma delta T cell clones was derived from synovial flui

97 Moreover, using gamma delta T cell clones, we determined that IL-15-indu

98 lls could inhibit tumor cell lysis by NK and gamma delta T cell clones.

99 In addition, purified gamma delta T cells, cocultured with purified monocytes

100 Thus, peripheral CD27(+) gamma/delta T cells, commonly considered as a functional

101 ultures showed a 10- to 50-fold expansion of gamma/delta T cells compared with the initial cellular i

102 icated that in nonlethal malaria infections, gamma delta T cells comprise a larger proportion of sple

103 These data indicate that gamma delta-T cells comprise a critical component of the

104 ally, the TCR complexes expressed on primary gamma delta T cells contain only zeta zeta homodimers; h

105 We conclude that gamma delta T cells contribute to the development of EAE

106 into several subsets, with Ly-6C(-) CD44(hi) gamma/delta T cells corresponding to the IL-17-producing

107 Splenic gamma delta T cells could be polarized into IFN-gamma- o

108 eria or related environmental Ags may induce gamma delta T cells cross-reactive with Ags present in t

109 S are the encephalitogenic T cells, and that gamma delta T cell-deficient mice are unable to resolve

110 s in IFN-gamma production were detectable in gamma delta T cell-deficient mice in the spleen and lymp

111 gamma delta T cell-deficient mice reconstituted with wil

112 Finally, hearts transplanted into gamma delta T cell-deficient mice resulted in decreased

113 This was shown using gamma delta T cell-deficient mice that were unable to re

114 In contrast, gamma delta T-cell-deficient mice exhibited decreased ce

115 kedly impaired in lung and liver tissue from gamma delta-T cell-deficient mice 24 h postinfection.

116 Moreover, only gamma/delta T cell-deficient animals had a decrease in t

117 Tibia fractures were created in 60 gamma/delta T cell-deficient mice (also called delta T c

118 n overall superior biomechanical strength in gamma/delta T cell-deficient mice compared with controls

119 eas T/R+ mice crossed with B cell-deficient, gamma/delta T cell-deficient, or major histocompatibilit

120 erated innate response was also increased in gamma/delta T-cell-deficient mice.

121 Animals deficient in gamma/delta T cells demonstrated more mature histologic

122 In gamma delta T cell-depleted animals, all of the chemokin

123 hemoattractant protein-1 at disease onset in gamma delta T cell-depleted mice, and total T cell numbe

124 In this study, we analyzed the effect of gamma delta T cell depletion on chemokine and chemokine

125 escued alpha beta T cell development but not gamma delta T cell development.

126 The special role of IL-7R signaling in gamma/delta T cell development has remained unclear.

127 To determine the role of IL-7R signaling in gamma/delta T cell development, we examined transcriptio

128 Proliferation of gamma delta T cells did not require prior immunization w

129 reconstituted with Fas ligand-dysfunctional gamma delta T cells did not.

130 al localization and functional properties of gamma delta T cells displaying a similarly restricted TC

131 dent signals, which lead to the expansion of gamma delta-T cells, do so by selectively protecting sub

132 Our studies suggest that gamma(delta) T cells, due to their ability to produce cy

133 ave previously reported that the presence of gamma delta T cells during certain inflammatory conditio

134 In the present study, an early increase of gamma(delta) T cells during murine infection with Enceph

135 were significantly higher in the absence of gamma/delta T cells during the innate phase of the respo

136 Furthermore, we demonstrate that gamma delta T cells elicited during a P. yoelii infectio

137 We examined the accumulation of gamma delta T cells elicited during infection with virul

138 Vgamma9/Vdelta2 were expressed on all gamma/delta T cells expanded by exposure of PBMC to Lept

139 ction, and bacteria were cleared well before gamma delta T cell expansion was detected 6 days after i

140 Coculture with CD4+ T cells induced optimal gamma delta T cell expansion, although IL-2 alone could

141 The gamma delta T cell expansions measured after in vitro st

142 Finally, prominent mycobacterial specific gamma delta T cell expansions were detected in a subset

143 Importantly, all CD1c-reactive gamma/delta T cells express V delta 1 TCRs, the TCR expr

144 function and repertoire of peripheral blood gamma delta T cells expressing the V gamma 2/V delta 2 T

145 antigens that are recognized by a subset of gamma delta T cells expressing the variable region Vdelt

146 induce any significant level of apoptosis in gamma delta T cells from healthy subjects or TB patients

147 less of freshly isolated CD4+ alpha beta or gamma delta T cells from normal healthy individuals and

148 t result in the selective expansion of human gamma delta-T cells from cultures of mitogen-stimulated

149 o by selectively protecting subsets of human gamma delta-T cells from mitogen-induced apoptosis.

150 T cells, it may early preferentially connect gamma delta T cell functions with those of cells that pr

151 t, suggesting that vector effects can negate gamma delta T-cell functions in vivo.

152 obtaining sufficient numbers of viable human gamma delta-T cells given their relative infrequency in

153 Ly-6C(- or +) CD44(lo) and Ly-6C(+)CD44(hi) gamma/delta T cells greatly resemble, and behave like, t

154 cific localization of TCR-defined subsets of gamma delta T cells has been widely reported; however, t

155 D8+ T cell immune response in the absence of gamma(delta) T cells has been demonstrated.

156 nce, however, that human, murine, and bovine gamma delta T cells have a role in the immune response t

157 However, increased frequencies of Vdelta1 gamma delta T cells have been observed in various epithe

158 Gamma delta T cells have been shown to regulate immune r

159 Human gamma delta T cells have the ability to rapidly expand a

160 mbined, these data suggest that mice lacking gamma delta-T cells have an impaired ability to resolve

161 Gamma(delta) T cells have been reported to play an essen

162 Finally, CD44(lo) gamma/delta T cells have an intrinsic high plasticity as

163 stion, we studied the resources that control gamma delta T cell homeostasis in secondary lymphoid org

164 Thus, gamma delta T cell homeostasis is maintained by trophic

165 Among normal splenocytes, as with gamma delta T cell hybridomas, the response was stronges

166 stence of two regulatory control pathways in gamma/delta T cells; IL-2 or PMA treatment induced a slo

167 ound a high frequency of V gamma 6/V delta 1 gamma delta T cells in both infected and autoimmune test

168 The role of gamma delta T cells in controlling the influx of inflamm

169 The importance of gamma delta T cells in corneal allograft survival was co

170 tood, although recent findings indicate that gamma delta T cells in general influence both innate and

171 8(+) T cells, there is a similar increase in gamma delta T cells in p27(Kip1)-deficient mice compared

172 and further support a pathological role for gamma delta T cells in patients with multiple sclerosis.

173 IL-15 may contribute to activation of human gamma delta T cells in the immune response to microbial

174 ifferential T cell reactivity, and that most gamma delta T cells in the normal spleen are present in

175 L-15 significantly enhanced the expansion of gamma delta T cells in the peripheral blood after stimul

176 r the predominant production of IFN-gamma by gamma delta T cells in the presence of IL-12, despite th

177 d the IL-15R alpha chain expression in human gamma delta T cells in the presence or absence of nonpep

178 ay contribute to the remarkable abundance of gamma delta T cells in this avian representative.

179 of inducing an increase in the percentage of gamma delta T cells in vivo.

180 ice, suggesting an immunoregulatory role for gamma/delta T cells in Candida vaginitis.

181 mmune response models of a critical role for gamma/delta T cells in down-modulation of the immune res

182 The present study investigated the role of gamma/delta T cells in experimental vaginal candidiasis.

183 The results indicate that the absence of gamma/delta T cells in IL-7Ralpha(-/-) mice is due to in

184 In contrast, IL-17+ gamma/delta T cells in lungs were unaffected.

185 Colon gamma/delta T cells in mice that lack conventional dendr

186 The evidence for a role of gamma/delta T cells in the context of skeletal injury de

187 partially dependent upon the presence of TCR-gamma/delta T cells in the host.

188 vels of FcRL3 on Treg cells, and on CD8+ and gamma/delta T cells, in comparison to RA patients with t

189 The majority of gamma delta T cells induced by BCG vaccination were gamm

190 ta T cells preferentially increase among the gamma delta T cells infiltrating inflamed tissues.

191 Although recent findings indicate that gamma delta T cells influence both early innate and Ag-s

192 Several studies have shown that gamma delta T cells influence granuloma development afte

193 The aim of our study was to investigate gamma/delta T cells, innate lymphocytes known to be invo

194 CD44 and Ly-6C subdivides murine peripheral gamma/delta T cells into several subsets, with Ly-6C(-)

195 8(-) cells; the maturation of CD4(-)8(+) and gamma delta T cells is normal.

196 Because one of the roles of gamma delta T cells is the regulation of inflammation, w

197 Bovine gamma delta T cells, isolated from the peripheral blood

198 Gamma delta T cell knockout mice displayed increased mor

199 Pulmonary bacterial clearance in gamma delta-T cell knockout mice was unimpaired.

200 , most gamma delta TCRs expressed on ex vivo gamma delta T cells lack CD3 delta.

201 uce poor protective immunity, the absence of gamma delta T cells led to significant reductions in bot

202 y and predominant production of IFN-gamma by gamma delta T cells likely is critical for the roles tha

203 thymocytes along the natural killer (NK) and gamma delta T-cell lineages.

204 Vdelta1 gamma delta T cell lines and clones derived from differe

205 strate a conservation of both alpha/beta and gamma/delta T cell localization in the thymus across 450

206 Among those patients with cutaneous gamma delta T-cell lymphoma (n = 33), there was a trend

207 Our results suggest that gamma delta T cells may be capable of developing a memor

208 and finally that different subpopulations of gamma delta+ T cells may either promote or inhibit Th1 c

209 Rather, gamma delta T cells mediated this effect indirectly thro

210 d immunodepleted mice, we found evidence for gamma/delta T-cell-mediated regulation of IFN-gamma prod

211 In the absence of gamma/delta T cells, mice die after infection with a dos

212 subsets (Th17, Th22) and at lower levels by gamma-delta T cells, NKT and innate lymphoid cells.

213 CD4 and CD8 alpha/beta T cells, gamma/delta T cells, NKT cells, regulatory T cells, and

214 Mitigation of GVHD by activated gamma delta T cells occurred only at high doses (150 x 1

215 We observe that gamma delta T cells of the V delta 1 subset accumulate i

216 receptors CD94:NKG2A and KIR2DL1 than either gamma delta T cells or NK cells.

217 e TCR alpha beta+ CD8+ T cells more than the gamma delta T cells or the TCR alpha beta+ CD4+CD8- popu

218 In the absence of gamma/delta T cells or after IL-17 neutralization, this

219 ent levels of cytokines normally produced by gamma/delta T cells or conversely from an excess of cyto

220 iveness was shown not to require CD8+ or TCR-gamma/delta+ T cells or IFN-gamma.

221 CD8(+) T cells, NK1.1 CD4(+) T (NKT) cells, gamma/delta T cells, or alpha/beta T cells indicated tha

222 Since gamma delta T cells play a major role in other forms of

223 The results suggest that gamma delta T cells play an important role in the CNS im

224 ver, in contrast to CD4+ alpha beta T cells, gamma delta T cells predominantly produced IFN-gamma, ev

225 nd others have seen that V gamma 6/V delta 1 gamma delta T cells preferentially increase among the ga

226 ce such cells represent close to half of the gamma delta T cells present in the liver and around 20%

227 nce of lipopolysaccharide and CD1-restricted gamma/delta T cells produced bioactive interleukin-12p70

228 factor, to modulate prenyl phosphate-induced gamma delta T cell proliferation and cytokine production

229 In mice lacking gamma delta T cells, proliferation of encephalitogenic T

230 These data suggest that CNS resident gamma delta T cells promote the production of IFN-gamma

231 Recognition by this tissue pool of gamma/delta T cells provides the human immune system wit

232 Surprisingly, we found that gamma delta T cells rather than CD4(+) and CD8(+) T cell

233 nhances regulatory T cell expansion; and (3) gamma delta T cells rather than CD4(+) and CD8(+) T cell

234 onses, it has remained unclear what triggers gamma delta T cell reactivity.

235 mphocytes in the blood of cattle express the gamma delta T-cell receptor, but specific functions for

236 and that antigen binding to alpha-beta or to gamma-delta T cell receptor does not play a role in tumo

237 te immunity [natural killer T cell (NKT) and gamma-delta T-cell receptor], and innate immunity can de

238 ass II+ CD11b- CD8alpha+ dendritic cells and gamma/delta T-cell receptor-bearing CD3+ T cells was pro

239 The promiscuous mode of gamma delta T cell recognition of these antigens may be

240 CD1-restricted gamma/delta T cell recognition of immature DCs provides

241 Human gamma delta T cells recognize prenyl pyrophosphate Ags a

242 -deficient mice reconstituted with wild-type gamma delta T cells recovered from EAE and resolved infl

243 Depletion of gamma delta T cells reduced expression of CCR1 and CCR5

244 Thus, gamma delta T cells regulate both inflammation in the CN

245 ool recapitulated the ontogenetic pattern of gamma delta T cell replenishment before alpha beta T cel

246 However, gamma delta T cells responded more strongly to the bacte

247 Both murine alpha beta and gamma delta T cells responded polyclonally to systemic b

248 The gamma delta T cell response proceeded in the absence of

249 dings emphasize the importance of CD4(+) and gamma-delta T-cell responses and have implications for i

250 Furthermore, the chimera blocked gamma delta T cell rolling on E-selectin.

251 Gamma delta T cells secrete Th1- and Th2-like cytokines

252 Previously, we showed that depletion of gamma delta T cells significantly reduced clinical and p

253 The CD8-positive gamma delta T cell subset did not accumulate at sites of

254 rearrangements not previously found in this gamma delta T cell subset, implying a difference in its

255 This is the first demonstration of a gamma delta T cell subset, which exhibits a defined tiss

256 The importance of alpha beta versus gamma delta T-cell subset antigen expression in the clas

257 corresponding to the IL-17-producing CD27(-) gamma/delta T cell subset exhibiting innate-like feature

258 We now show that T cells of the major tissue gamma/delta T cell subset recognize nonpolymorphic CD1c

259 n some cases tissue-specific accumulation of gamma delta T cell subsets can be predicted by expressio

260 In this capacity, certain gamma delta T cell subsets may serve as cytolytic sentin

261 stence of distinct phenotypic and functional gamma/delta T cell subsets.

262 Recent studies have suggested that the gamma(delta) T cell subtype may also be important for th

263 We describe a bovine gamma delta T cell TCR-associated subset that preferenti

264 Among unstimulated splenocytes, more gamma delta T cells than alpha beta T cells expressed CD

265 nized by diverse human intestinal epithelial gamma delta T cells that are restricted by MICA and MICB

266 ynovial fluid contains a large proportion of gamma delta T cells that proliferates upon stimulation w

267 inflammation as efficiently as CD8-negative gamma delta T cells that, in contrast, express E-selecti

268 AICD of gamma delta T cells, therefore, provides an explanation

269 his study investigated the ability of bovine gamma delta T cells to expand and produce gamma interfer

270 as shown to be independent of the ability of gamma delta T cells to produce IFN-gamma, and was specif

271 IL-12 also induced IL-4-primed gamma delta T cells to proliferate and to translocate St

272 These results and the inability of V(delta)1 gamma delta T cells to respond to target cells expressin

273 may thus selectively evoke contributions of gamma delta T cells to the host response.

274 The stronger response of gamma delta T cells to TNF-alpha was correlated with hig

275 The ability of human gamma delta-T cells to mediate a number of in vitro func

276 a 1+ cells again represented the predominant gamma delta T cell type.

277 Third, CD44(lo) gamma/delta T cells undergo spontaneous proliferation an

278 Among T cell subsets, gamma delta T cells uniquely display an Ag receptor-base

279 examined the repertoire of the infiltrating gamma delta T cells, using two different methods, and fo

280 in mice transplanted with BM plus activated gamma delta T cells vs those given marrow cells alone.

281 ansgenic mice, IL-4 production by peripheral gamma delta T cells was confined to the gamma delta+9D3+

282 , because acute homeostatic proliferation of gamma delta T cells was inhibited by an intact alpha bet

283 We show that the presence of gamma delta T cells was needed to promote the production

284 regulation of inflammation, we asked whether gamma delta T cells were able to regulate CNS inflammati

285 rpose of this study was to determine whether gamma delta T cells were able to regulate graft-vs-host

286 ence of metalloproteinase-inhibitors >70% of gamma delta T cells were FasL+.

287 Gamma delta T cells were found to provide helper functio

288 gamma delta T cells were found to rapidly expand and pro

289 doptive transfer of DTH assay, we found that gamma delta T cells were required for the generation of

290 itive for MICA/B, the frequencies of Vdelta1 gamma delta T cells were significantly higher than in th

291 Using this model we found that gamma delta T cells were still plentiful among the infil

292 Mice lacking gamma(delta) T cells were susceptible to E. cuniculi inf

293 Responses by gamma-delta T cells were 6-fold higher in seropositive t

294 The CD1c-reactive gamma/delta T cells were cytotoxic and used both perfori

295 for gamma/delta T cells, and CCL8-responsive gamma/delta T cells were enriched for IL-17F.

296 Similarly, T cell receptor (TCR)-gamma/delta T cells were not required for maximal inhibi

297 tes, CD4 and CD8 T cells, and alpha/beta and gamma/delta T cells were uniformly positive for PSGL-1,

298 g for at least 3 wk after stimulation of the gamma delta T cells with Borrelia burgdorferi.

299 allograft survival was confirmed by blocking gamma delta T cells with GL3 Ab before corneal transplan

300 Human gamma delta T cells with the TCR variable region V(delta