ライフサイエンスコーパス: gamma-actin

1 changed expression pattern with dominance of gamma-actin.

2 dmilling is twice as fast with beta- as with gamma-actin.

3 hate release lags behind polymerization with gamma-actin.

4 e modified proteins were myosin II and alpha/gamma-actin.

5 d amino acid sequences corresponding to beta/gamma-actin.

6 binding factor 1, Ig H chain, stathmin, and gamma-actin.

7 xin V to a specific isoform of actin, namely gamma-actin.

8 V is in nonmuscle cells expressing beta- and gamma-actin.

9 ated new antibodies specific for cytoplasmic gamma-actin and confirmed that gamma-actin most predomin

10 The damage to gamma-actin and DNA polymerase-beta genes was detected w

11 ith genes encoding the non-secreted proteins gamma-actin and glyceraldehyde 3'-phosphate dehydrogenas

12 dystrophin-glycoprotein complex) as well as gamma-actin and microtubules and also is required to ali

13 s2 and IkappaB), cytoskeletal proteins (e.g. gamma-actin), and transcription factors (e.g. c-Fos, Egr

14 endoplasmic reticulum ATPase, a cytoskeletal gamma actin, and Trax, were specifically immunoprecipita

15 tory proteins such as telokin, smooth muscle gamma-actin, and Cav1.2b in visceral SMCs.

16 mediated modification of myosin II and alpha/gamma-actin, and cell cycle perturbation.

17 binding protein 1, glutamate dehydrogenase, gamma-actin, and elongation factor Tu were identified as

18 c alpha-actin, vascular alpha-actin, enteric gamma-actin, and skeletal alpha-actin, were present in b

19 he mammalian cytoskeletal proteins beta- and gamma-actin are highly homologous, but only beta-actin i

20 We found that two actin isoforms, beta- and gamma-actin, are crucial for slow, rapid, bulk, and over

21 Although two actin isoforms, beta- and gamma-actin, are expressed in dendritic spines, the spec

22 This process requires both beta-actin and gamma-actin as knock-out mice lacking either isoform dev

23 ) mice consequently have increased levels of gamma-actin at hippocampal synapses, resulting in higher

24 Six point mutations in non-muscle gamma-actin at the DFNA20/26 locus cause autosomal domin

25 g the most elastic, smooth muscle alpha- and gamma-actins being less elastic, and beta-actin not form

26 contain spectrin, tropomyosin, and beta- and gamma-actin, but espin was not detected; spectrin is als

27 Modification of myosin II and gamma-actin by KYN may interfere with cytokinesis, leadi

28 mic RNA were the isolation of both beta- and gamma-actin cDNA clones.

29 uscle alpha-actin, and enteric smooth muscle gamma-actin comprise the major actins in their respectiv

30 p1-Rhotekin, D6Mm3e-Dynactin 1-Smooth muscle gamma actin-D6Mm4e-beta-adducin-telomere.

31 Ca-gamma-actin depolymerizes half as fast as does beta-acti

32 beling of tropomyosin, spectrin, beta-actin, gamma-actin, espin, and prestin.

33 Surprisingly, Ca-gamma-actin exhibits a slower monomeric nucleotide excha

34 Profilin binds to beta,gamma-actin filament barbed ends with an equilibrium con

35 (alpha) and human non-muscle (85% beta, 15% gamma) actin filaments from the quenching of pyrene acti

36 n cofilin binding to human nonmuscle (beta-, gamma-) actin filaments.

37 A population of gamma-actin filaments was stably associated with sarcole

38 Fascin-2 binds beta-actin and gamma-actin filaments with similar affinity in vitro and

39 americ cytoskeleton through interaction with gamma-actin filaments.

40 ere, we tested the hypothesis that beta- and gamma-actin functions are defined by their nucleotide, r

41 deletion on the organization of cytoplasmic gamma-actin (gamma(cyto)-actin) in the SR of skeletal mu

42 Sequence analysis of the gamma-actin gene (ACTG1) revealed missense mutations in

43 alian endogenous dihydrofolate reductase and gamma-actin genes have been used to study the associatio

44 RAP recovery rate and the mobile fraction of gamma-actin-GFP both decreased as the bands thickened wi

45 nctions in utricles from mice that express a gamma-actin-GFP fusion protein showed that the thickenin

46 an Asp(1)-Asp(2)-Asp(3) and Val(10) whereas gamma-actin has a Glu(1)-Glu(2)-Glu(3) and Ile(10).

47 Currently, ten point mutations in nonmuscle gamma-actin have been identified as causing progressive

48 elocates to the plasma membrane and binds to gamma-actin in an activation-dependent manner forms a st

49 We conclude that increased cytoplasmic gamma-actin in dystrophin-deficient muscle may be a comp

50 ndritic spines, the specific contribution of gamma-actin in the expression of synaptic plasticity is

51 ebulin M1M2M3 domain, Tmod3, and cytoplasmic gamma-actin, indicating that m-calpain does not cause wh

52 Analysis of the alpha-, beta-, and gamma-actin isoforms in SPARC knockout myoblasts reveals

53 Ubiquitously expressed beta-actin and gamma-actin isoforms play critical roles in most cellula

54 We show that synaptic gamma-actin levels are regulated by the E3 ubiquitin lig

55 ur findings suggest that temporal control of gamma-actin levels by TRIM3 is required to regulate the

56 However, we observed that gamma-actin levels were increased 10-fold at the sarcole

57 owever, the presence of excessive myoplasmic gamma-actin may also contribute to altered cell signalin

58 m bound in the high affinity binding site of gamma-actin may cause a selective energy barrier relativ

59 r cytoplasmic gamma-actin and confirmed that gamma-actin most predominantly localized to the sarcolem

60 TRIM3 polyubiquitylates gamma-actin, most likely cotranslationally at synaptic s

61 ach cloned actin gene and alpha-, beta-, and gamma-actin mRNA demonstrated that only one of the clone

62 the precise quantification of a specific rat gamma-actin mRNA sequence amplified by the polymerase ch

63 has been applied to the analysis of specific gamma-actin mRNA sequences amplified by polymerase chain

64 pid localization of beta-actin mRNA, but not gamma-actin mRNA, into processes and growth cones could

65 mRNA, vimentin, beta-tubulin, and beta- and gamma-actin mRNAs were mainly confined to the cell bodie

66 neuronal processes and growth cones, unlike gamma-actin mRNAs, which were restricted to the cell bod

67 We have engineered each gamma-actin mutation into yeast actin to investigate the

68 fibroblasts (MEFs) that were not observed in gamma-actin-null MEFs.

69 Myoblasts expressing either human gamma-actin or the mutant beta-actin down-regulate the e

70 interaction of profilin and non-muscle beta,gamma-actin prepared from bovine spleen has been investi

71 barbed end using profilin and nonmuscle beta,gamma-actin prepared from bovine spleen.

72 Smooth muscle-gamma-actin promoter-luciferase reporter activity was en

73 protein by editing beta-actin gene to encode gamma-actin protein, and vice versa, does not affect cel

74 ing growth factor-beta induced smooth muscle-gamma-actin protein, cytoskeletal localization, and mRNA

75 n growth cones and filopodia, in contrast to gamma-actin protein, which was distributed uniformly thr

76 .40 vs. after treatment, 0.003, P=0.001; IFN-gamma:actin ratio: before treatment, 0.32 vs. after trea

77 ansgenically expressed enteric smooth muscle gamma-actin reduces cardiac contractility in wild-type a

78 stored gamma-actin to normal levels, whereas gamma-actin remained elevated in mdx muscle expressing n

79 particularly important in sites such as the gamma-actin-rich cochlear hair cell stereocilium where l

80 ate kinase, glycogen phosphorylase, actinin, gamma-actin, ryanodine receptor 3, and neurogenic locus

81 FP mRNA in mature DRG neurons, but mice with gamma-actin's 3'-UTR show no axonal GFP mRNA.

82 ation in vitro demonstrated that polymerized gamma-actin sequestered EGFP-YY1 in the cytoplasm and th

83 -1 was evaluated for mediating smooth muscle gamma-actin (SMGA) gene activity, a specific marker of s

84 o activate expression from the smooth muscle gamma-actin (SMGA) gene promoter.

85 s interactions found along the smooth muscle gamma-actin (SMGA) promoter.

86 this effect is much more pronounced for beta,gamma-actin than for alpha-skeletal muscle actin.

87 ystrophin constructs in mdx muscle, restored gamma-actin to normal levels, whereas gamma-actin remain

88 a constant level of actin mRNA, whereas the gamma-actin transfectants do not down-regulate ADF.

89 se a model in which TRIM3 regulates synaptic gamma-actin turnover and actin filament stability and th

90 Arginylated gamma-actin, unlike beta-, was highly unstable and was s

91 , leading to the preferential degradation of gamma-actin upon arginylation.

92 ectopic expression of enteric smooth muscle gamma-actin using the cardiac alpha-myosin heavy chain p

93 gamma-actin was translated more slowly than beta-actin,

94 on the molecular regulation of smooth muscle-gamma-actin, whose expression is induced at late stages

95 When we stopped expression of beta- or gamma-actin with tamoxifen-inducible recombination, neit

96 distinct localization patterns for beta- and gamma-actin within cultured cerebrocortical neurons.