ライフサイエンスコーパス: gamma-tocopherol

1 with vitamin E-antioxidant activity, such as gamma-tocopherol.

2 s) while pistachios and walnuts were rich in gamma-tocopherol.

3 tein, and lycopene), retinol, and alpha- and gamma-tocopherol.

4 ntion of alpha-tocopherol and elimination of gamma-tocopherol.

5 carotene, beta-cryptoxanthin, and alpha- and gamma-tocopherol.

6 hin, lycopene, retinol, alpha-tocopherol, or gamma-tocopherol.

7 d high levels of its biosynthetic precursor, gamma-tocopherol.

8 6-hydroxychroman, presumably a metabolite of gamma-tocopherol.

9 oil and the major isoform in all samples was gamma-tocopherol.

10 copherol or the ratio of alpha-tocopherol to gamma-tocopherol.

11 3-2 allele is deficient in PQ and alpha- and gamma-tocopherols.

12 alpha-tocopherol equivalents, and alpha- and gamma-tocopherols.

13 associated with lycopene, beta-carotene, and gamma-tocopherol (0.56, 0.54, and 0.52, respectively; p

14 pherol, 2.90 +/- 0.6 pmol per mg, p < 0.001; gamma-tocopherol, 0.5 +/- 0.1 pmol per mg, p < 0.001) an

15 lpha-tocopherol 6.5 +/- 1.4 pmol per mg, and gamma-tocopherol 2.2 +/- 1.3 pmol per mg) and the highes

16 iously, we reported that Akt inactivation by gamma-tocopherol (2) in PTEN-negative prostate cancer ce

17 (alpha-tocopherol, 8.95 +/- 1.3 pmol per mg; gamma-tocopherol, 3.00 +/- 0.3 pmol per mg; MDA, 3.69 +/

18 analyzed for total ascorbic acid, alpha- and gamma-tocopherols, 5 carotenoids, retinol, and cotinine.

19 (55-74%), phytosterols (3200-7600mg/kg) and gamma-tocopherol (550-720mg/kg).

20 (alpha-tocopherol 76 +/- 12 pmol per mg, and gamma-tocopherol 7.9 +/- 3.7 pmol per mg, n = 10; p < 0.

21 Unique characteristic is the high content of gamma-tocopherol (75.4mg/100g) and delta-tocopherol (34.

22 of delivery and were analyzed for alpha- and gamma-tocopherol, alpha- and gamma-CEHC, and total lipid

23 Plasma gamma-tocopherol also was higher in subjects with oxidat

24 n/zeaxanthin, retinol, alpha-tocopherol, and gamma-tocopherol and breast cancer risk by conducting a

25 iologic data concerning the relation between gamma-tocopherol and cardiovascular disease and cancer.

26 chemistry, and nonantioxidant activities of gamma-tocopherol and epidemiologic data concerning the r

27 Both gamma-tocopherol and gamma-CEHC, but not alpha-tocophero

28 These distinguishing features of gamma-tocopherol and its metabolite suggest that gamma-t

29 ated with higher levels of beta-tocopherol + gamma-tocopherol and lower levels of carotenoids and ret

30 trode, in the presence of alpha-, delta- and gamma-tocopherol and olive oil samples, respectively.

31 d significantly higher contents of alpha and gamma-tocopherol and phenolic compounds contents and hig

32 ) in glutinous rice, while alpha-tocopherol, gamma-tocopherol and polyunsaturated fatty acids (PUFA)

33 A strong inverse association between gamma-tocopherol and prostate cancer risk was observed i

34 carotenoids, retinol, alpha-tocopherol, and gamma-tocopherol and prostate cancer risk.

35 nthin, lutein, and lycopene) plus alpha- and gamma-tocopherol and retinol using high-performance liqu

36 lasma ascorbate was significantly lower, but gamma-tocopherol and TAS were significantly higher in su

37 itis and serum levels of alpha-, delta-, and gamma-tocopherol and the alpha:gamma-tocopherol ratio in

38 maternal plasma concentrations of alpha- and gamma-tocopherols and examined their relation with measu

39 generic term for alpha-, beta-, delta-, and gamma-tocopherols and tocotrienols, which are primarily

40 trations of ascorbate, urate, and alpha- and gamma-tocopherols and with total antioxidant status (TAS

41 lations to circulating vitamin E (alpha- and gamma-tocopherol) and maternal dietary vitamin E intake.

42 urrent study retinol, tocopherol (alpha- and gamma-tocopherols), and carotenoid (lutein/zeaxanthin, c

43 protected from CIN by superoxide dismutase, gamma-tocopherol, and cyclooxygenase-2 (COX-2) inhibitor

44 th variable ratios and amounts of alpha- and gamma-tocopherol, and other minor compounds.

45 ta-cryptoxanthin, retinol, alpha-tocopherol, gamma-tocopherol, and vitamin C.

46 gamma-Tocopherol appears to be a more effective trap for

47 Plasma and adipose tissue concentrations of gamma-tocopherol are equally good biomarkers of intake.

48 udies indicate that plasma concentrations of gamma-tocopherol are inversely associated with the incid

49 adipose tissue concentrations of alpha- and gamma-tocopherol are suitable biomarkers of intake.

50 tinol, and tocopherols (alpha-tocopherol and gamma-tocopherol) are decreased in women with preeclamps

51 e tocopherol content was 121.85 mg/100g with gamma-tocopherol as the major one (95.49%).

52 Moreover, d-gamma-tocopherol, at as little as 10% the concentration

53 y measuring ascorbic acid, alpha-tocopherol, gamma-tocopherol, beta-carotene, and lycopene, and subse

54 r adjustment for age, race, age at menarche, gamma-tocopherol, beta-carotene, total cholesterol, and

55 ith CRR1-dependent increased accumulation of gamma-tocopherols, but not plastoquinone-9 nor total toc

56 simulated UVR (alpha-tocopherol by 45%, and gamma-tocopherol by 35% as compared with controls; n = 6

57 chromatography, and retinol and alpha-, and gamma-tocopherol by liquid chromatography.

58 lar at the amino acid level to the plastidic gamma-tocopherol C methyltransferases of vitamin E biosy

59 anthus roseus showing distinct similarity to gamma-tocopherol C-methyltransferases was used in a bioi

60 Plasma concentrations of alpha- and gamma-tocopherol, carotenoids, and retinol were measured

61 alpha- and gamma-Tocopherols, cholesterol, and triglycerides were m

62 tamin E status, we assayed plasma alpha- and gamma-tocopherol concentration for 332 subjects with col

63 of 1.83 (95% CI: 1.04, 3.20), whereas a low gamma-tocopherol concentration was associated with an OR

64 fer by smoking status or by plasma alpha- or gamma-tocopherol concentration.

65 ol/L, respectively) and significantly higher gamma-tocopherol concentrations (7.8, 7.8, and 6.5 micro

66 Plasma glutathione (GSH) and alpha- and gamma-tocopherol concentrations decreased and the GSH re

67 However, only gamma-tocopherol concentrations were higher in the plasm

68 In all women, plasma alpha- and gamma-tocopherol concentrations were low [median (IQR):

69 Plasma alpha- and gamma-tocopherol concentrations were measured.

70 r research is required to explain why plasma gamma-tocopherol concentrations were significantly highe

71 Plasma alpha- and gamma-tocopherol concentrations, plasma total antioxidan

72 pha-tocopherol and inversely associated with gamma-tocopherol concentrations.

73 Gamma-tocopherol content is higher in 'Galega Vulgar' VO

74 ld type, primarily because of an increase in gamma-tocopherol content.

75 Dietary gamma-tocopherol correlated with adipose tissue (r = 0.3

76 entrations of alpha-tocopherol increased and gamma-tocopherol decreased.

77 B(4) (LTB(4)) with an IC(50) of 5-20 muM for gamma-tocopherol, delta-tocopherol (deltaT), and gamma-t

78 alpha-tocopherol, gamma-tocopherol, delta-tocopherol, beta-carotene, lutei

79 thyl hydrochroman (gamma-CEHC), a vitamin E (gamma-tocopherol) derivative (OR: 1.64; 95% CI: 1.18, 2.

80 (<0.81 mumol/L; upper tertile cutoff of the gamma-tocopherol distribution in women who did not misca

81 25-hydroxyvitamin D3, alpha-tocopherol (E), gamma-tocopherol (E), and phylloquinone (K1) by LC-MS/MS

82 We demonstrate that the isoform d-gamma-tocopherol elevates inflammation in experimental a

83 serum concentrations of alpha-tocopherol and gamma-tocopherol exist among US adults.

84 al, which was measured by monitoring 5-nitro-gamma-tocopherol formation.

85 resolves 11 carotenoids, retinol, alpha- and gamma-tocopherol from complex matrixes such as food samp

86 o-3-phosphatidylcholine liposomes containing gamma-tocopherol (gamma-TH) were incubated with SOD/H2O2

87 We and others have shown that the gamma tocopherol (gammaT) isoform of vitamin E has multi

88 Here we report that gamma-tocopherol (gammaT) reduced PGE(2) synthesis in bo

89 he most common dietary isoform of vitamin E, gamma-tocopherol (gammaT), could suppress FcepsilonRI-me

90 Gamma-tocopherol (gammaT), the major form of vitamin E i

91 gamma-Tocopherol (gammaT), the predominant form of vitam

92 We examined how gamma-tocopherol (gammaT), the principal form of vitamin

93 tocotrienol approximately delta-tocopherol > gamma-tocopherol >> alpha- or beta-tocopherol.

94 alpha- and gamma-Tocopherol had independent associations.

95 uced NF-kappaB activation, a similar dose of gamma-tocopherol had no effect.

96 serum concentrations of alpha-tocopherol and gamma-tocopherol in a nationally representative sample o

97 ns and men, positively associated with serum gamma-tocopherol in men, and unassociated with serum del

98 flammatory effects of supplemental levels of gamma-tocopherol in phase 1 were only partially reversed

99 d by the SOD1/H(2)O(2)-mediated nitration of gamma-tocopherol in the presence of nitrite.

100 cumulation of delta-tocopherol and decreased gamma-tocopherol in the seed.

101 (52%) had higher amounts of both alpha- and gamma-tocopherol in their diets.

102 d VTE1 proteins are able to convert DMPBQ to gamma-tocopherol in vitro.

103 bran compared to raw bran, while alpha- and gamma-tocopherols in hot-air and cellulase treated rice

104 f alpha-tocopherol deplete plasma and tissue gamma-tocopherol, in contrast with supplementation with

105 Only serum tocopherol (the sum of alpha- and gamma-tocopherol, in micromol/mmol cholesterol) was asso

106 lung lavage fluid, highly elevated levels of gamma-tocopherol increased inflammation in the lung tiss

107 alpha-tocopherol and the ratio of alpha- to gamma-tocopherol increased significantly in both supplem

108 er and higher quarters of alpha-carotene and gamma-tocopherol increased the risk of asthma.

109 s biomarkers of intake, the relation between gamma-tocopherol intake and concentrations in plasma and

110 Neither alpha- nor gamma-tocopherol intake from foods was associated with B

111 mma-tocopherol methyl transferase converting gamma-tocopherol into alpha-tocopherol) associated with

112 gamma-Tocopherol is effective scavengers of reactive nit

113 gamma-tocopherol is the major form of vitamin E in many

114 gamma-Tocopherol is the most abundant form of vitamin E

115 gamma-Tocopherol is well absorbed and accumulates to a s

116 Vitamin E (alpha-gamma-tocopherol) is an important component in biologica

117 ed that supplemental doses of the alpha- and gamma-tocopherol isoforms of vitamin E decrease and incr

118 Increasing alpha-tocopherol and decreasing gamma-tocopherol levels were associated with decreased o

119 elevated tocopherol) so that the lung tissue gamma-tocopherol levels were equal to the lung tissue le

120 When gamma-tocopherol levels were increased 10-fold (highly e

121 occurred as a result of the evolution of the gamma-tocopherol-like N-methyltransferase family from ga

122 fia serpentina, and C. roseus to identify 10 gamma-tocopherol-like N-methyltransferases from a large

123 ith low alpha-tocopherol (<12.0 mumol/L) and gamma-tocopherol (<0.81 mumol/L; upper tertile cutoff of

124 However, recent studies indicate that gamma-tocopherol may be important to human health and th

125 a-tocopherol and its metabolite suggest that gamma-tocopherol may contribute significantly to human h

126 All key intermediates of gamma-tocopherol metabolism via this pathway were identi

127 70.1, an orthologue of VTE4 (which encodes a gamma-tocopherol methyl transferase converting gamma-toc

128 localized proteins were identified including gamma-tocopherol methyltransferase (gamma-TMT).

129 a-tocopherols, respectively, indicating that gamma-tocopherol methyltransferase activity limits alpha

130 s by combined overexpression of the HPT1 and gamma-tocopherol methyltransferase genes.

131 Overexpression of gamma-tocopherol methyltransferase in Arabidopsis seeds

132 Overexpression of gamma-tocopherol methyltransferase in the 35S::HPT1 back

133 e phytyltransferase, tocopherol cyclase, and gamma-tocopherol methyltransferase) and rationally desig

134 When At-VTE3 was coexpressed with At-VTE4 (gamma-tocopherol methyltransferase) in soybean, the seed

135 nts with lines constitutively overexpressing gamma-tocopherol methyltransferase.

136 final enzyme in alpha-tocopherol synthesis, gamma-tocopherol methyltransferase.

137 opherol-like N-methyltransferase family from gamma-tocopherol methyltransferases.

138 Also, gamma-tocopherol might have functions apart from being a

139 the proinflammatory effects of supplemental gamma-tocopherol on lung inflammation were partially rev

140 suggest potential chemopreventive effects of gamma-tocopherol on prostate cancer.

141 st abundant isomers of vitamin E (alpha- and gamma-tocopherols) on fetal growth.

142 alpha-tocopherol OR = 3.6, 95% CI: 1.4, 9.4; gamma-tocopherol OR = 5.3, 95% CI: 2.1, 13.2; delta-toco

143 s, little is known about the distribution of gamma-tocopherol or the ratio of alpha-tocopherol to gam

144 asma, while the other vitamin E forms (e.g., gamma-tocopherol or tocotrienols) are removed from the c

145 enuated by the presence of alpha-tocopherol, gamma-tocopherol, or ascorbate.

146 nges in lycopene, retinol, alpha-tocopherol, gamma-tocopherol, or total cholesterol concentrations.

147 y intermediates, and 23 potential alpha- and gamma-tocopherol oxidation products.

148 Fine-mapping has narrowed QVE7 (a gamma-tocopherol quantitative trait loci) to an 8.5-kb i

149 and partially substituted vitamin E congener gamma-tocopherol quinone (gamma-TQ), were cytotoxic, wit

150 versus lowest quintile of alpha-tocopherol: gamma-tocopherol ratio had an odds ratio of 0.36 (95% co

151 Persons in the highest tertile of the alpha:gamma-tocopherol ratio had half the odds of radiographic

152 , delta-, and gamma-tocopherol and the alpha:gamma-tocopherol ratio in African-American and White adu

153 The finding that a high alpha-tocopherol:gamma-tocopherol ratio is associated with decreased occu

154 A high plasma alpha-tocopherol:gamma-tocopherol ratio may be a better predictor of decr

155 ) was observed by using the alpha-tocopherol:gamma-tocopherol ratio, which may be a more sensitive in

156 sue levels of supplemental alpha-tocopherol, gamma-tocopherol reduced leukocyte numbers in the lung l

157 itive associations observed for lycopene and gamma-tocopherol require confirmation.

158 +/- 1.3 and 1101 +/- 22 mug/g of alpha- and gamma- tocopherols, respectively, in P. curatellifolia b

159 ate, retinyl palmitate, alpha-tocopherol and gamma-tocopherol, reverse phase high performance liquid

160 The median concentrations of gamma-tocopherol showed a trend with respect to age, did

161 Men with higher plasma levels of gamma-tocopherol tended to have an increased risk of MI

162 but markedly higher catalytic activities for gamma-tocopherol than alpha-tocopherol, suggesting a rol

163 In CLUE I, cases had lower concentrations of gamma-tocopherol than did controls (p = 0.02), but no do

164 We found that gamma-T3 but not gamma-tocopherol, the most common saturated form of vita

165 Thus, the ability of gamma-tocopherol to inhibit COX-2 activity independently

166 cholesterol was 4.93 micromol/mmol, that of gamma-tocopherol to total cholesterol was 1.03 micromol/

167 cromol/mmol, and that of alpha-tocopherol to gamma-tocopherol was 4.53 micromol/mmol.

168 e arithmetic mean of serum concentrations of gamma-tocopherol was 5.74 +/- 0.22 micromol/L, the media

169 This enlarged pool of gamma-tocopherol was almost entirely converted to alpha-

170 Plasma gamma-tocopherol was associated only with knee extension

171 with increased risk of miscarriage, and low gamma-tocopherol was associated with decreased risk of m

172 rsely associated with breast cancer and that gamma-tocopherol was associated with increased risk.

173 In all oil samples, the loss of gamma-tocopherol was higher than the corresponding loss

174 gamma-Tocopherol was not associated with risk.

175 ietary intake of vitamin E; concentration of gamma-tocopherol was related positively to dietary fat i

176 Among lipophilic tocochromanols gamma-tocopherol was the most abundant isomer in the sam

177 A significant increase in alpha- and gamma-tocopherols was found in FIR irradiated rice bran

178 Alpha-, beta-, and gamma-tocopherol were associated with an approximate two

179 ester concentrations of alpha-tocopherol and gamma-tocopherol were associated with reduced odds of mi

180 lutein, zeaxanthin, beta-carotene and alpha-/gamma-tocopherol were determined in different varieties

181 Also, highly elevated levels of gamma-tocopherol were inhibitory and reversible in lung

182 Concentrations of alpha-tocopherol and gamma-tocopherol were measured by using HPLC with ultrav

183 ds and monounsaturated fatty acids and serum gamma-tocopherol were weakly associated with intake (R(2

184 Carotenoids and alpha- and gamma-tocopherols were not associated with either genoty

185 ons of individual carotenoids and alpha- and gamma-tocopherol, were determined from serum obtained at

186 herol, in contrast with supplementation with gamma-tocopherol, which increases both.

187 is reminiscent of the anticancer activity of gamma-tocopherol, which reduces NO(2) to NO and protects

188 asterol, campesterol, and alpha-, delta- and gamma-tocopherols, while lutein was quantified with visi

189 carotenoids, retinol, alpha-tocopherol, and gamma-tocopherol with risk of prostate cancer and to des