ライフサイエンスコーパス: gammaretrovirus

1 in of Moloney murine leukemia virus (MLV), a gammaretrovirus.

2 ld support infection of a pseudotyped modern gammaretrovirus.

3 6.9% nucleotide identity to the killer whale gammaretrovirus.

4 loney murine leukemia virus (MoMLV), another gammaretrovirus.

5 ull-length viral genome with that of another gammaretrovirus.

6 in mice by MoFe2-MuLV, a unique recombinant gammaretrovirus.

7 nfected with murine leukemia virus (MuLV), a gammaretrovirus.

8 by the polytropic host range group of mouse gammaretroviruses.

9 not previously reported for mouse ecotropic gammaretroviruses.

10 ning proteins similar to receptors for other gammaretroviruses.

11 e residues are also conserved in the RSEs of gammaretroviruses.

12 entry mediated by Env proteins of delta- and gammaretroviruses.

13 roducer cells are superinfected with certain gammaretroviruses.

14 ions for the selection of antivirals against gammaretroviruses.

15 e LTR associated with increased pathology in gammaretroviruses.

16 ation near transcriptional start sites, like gammaretroviruses.

17 ntified as invariant among highly infectious gammaretroviruses.

18 sh endogenous retrovirus (ZFERV) between the Gammaretrovirus and Epsilonretrovirus genera.

19 postentry determinant of the host range for gammaretroviruses and lentiviruses and, more recently, s

20 stem to evaluate the in vivo spread of these gammaretroviruses and their disease potential in their n

21 nonprimate lentiviruses, a Betaretrovirus, a Gammaretrovirus, and the Alpharetrovirus Rous sarcoma vi

22 Class I includes gammaretroviruses, and class II includes lentiviruses an

23 entiviruses, spumaviruses, betaretroviruses, gammaretroviruses, and other elements containing reverse

24 NA transcripts, and RNA export mechanisms of gammaretroviruses are poorly characterized.

25 Lentiviruses, unlike the gammaretroviruses, are able to infect nondividing cells

26 sequences and baboon endogenous virus type C gammaretrovirus (BaEV) sequences were induced by AzaC, w

27 rom adult killer whales and detected a novel gammaretrovirus by degenerate PCR.

28 Nonspecific inactivation of gammaretroviruses by serum factors appears insufficient

29 mate lentiviruses are distinguished from the gammaretroviruses by their ability to infect nondividing

30 The 5'-untranslated regions of all gammaretroviruses contain a conserved "double-hairpin mo

31 The surface glycoprotein (SU) of most gammaretroviruses contains a conserved histidine at its

32 Here we report on a novel endogenous gammaretrovirus (CrERVgamma; for cervid endogenous gamma

33 For gammaretroviruses, CV-N inhibited entry mediated by some

34 rk, a series of INs from the Betaretrovirus, Gammaretrovirus, Deltaretrovirus, Spumavirus and Lentivi

35 Recently, a new endogenous koala gammaretrovirus, designated KoRV, was isolated from koal

36 o predicted nucleosome positions showed that gammaretroviruses direct integration into outward-facing

37 virus-related virus (XMRV) is a novel human gammaretrovirus discovered in association with human pro

38 The env gene of gammaretroviruses encodes a glycoprotein conserved among

39 We suggest that this gammaretrovirus entered the delphinoid ancestor's genome

40 Here we show that pairs of gammaretrovirus envelope proteins (from Friend virus and

41 e been elucidated, with the exception of the gammaretrovirus family.

42 ine leukemia virus-related virus (XMRV) is a gammaretrovirus found in association with human prostate

43 tion, and from recent cross-species jumps of gammaretroviruses from rodents to primates and marsupial

44 est relatives of CrERVgamma being endogenous gammaretroviruses from sheep and pig.

45 virus, spumaretrovirus, alpharetrovirus, and gammaretrovirus genera, no members of the deltaretroviru

46 d identification of a previously undescribed gammaretrovirus genome, xenotropic murine leukemia virus

47 istribution, origin, and transmission of the Gammaretrovirus genus and associated class I ERVs.

48 The mammalian gammaretroviruses gibbon ape leukemia virus (GALV) and f

49 shares 78% nucleotide identity with another gammaretrovirus, gibbon ape leukemia virus (GALV).

50 Like the primate lentivirus Nef and the gammaretrovirus glycoGag, the accessory protein from EIA

51 ein does not assemble in heteromers with the gammaretrovirus glycoproteins tested and does not affect

52 iently forms pseudotyped particles with many gammaretrovirus glycoproteins, such as Friend murine leu

53 urine leukemia virus-related virus (XMRV), a gammaretrovirus, has been isolated from human prostate c

54 While gammaretroviruses have well-characterized oncogenic effe

55 A close relative of gammaretroviruses, HERV-T, circulated in primates for 2

56 ia virus-related virus (XMRV) is a new human gammaretrovirus identified in prostate cancer tissue fro

57 etrovirus (CrERVgamma; for cervid endogenous gammaretrovirus) in the mule deer (Odocoileus hemionus)

58 served cis-acting element in the pol gene of gammaretroviruses, including murine leukemia virus (MLV)

59 All gammaretroviruses, including murine leukemia viruses (Mu

60 basal promoter elements compared with other gammaretroviruses, including the presence of enhancer-li

61 Gammaretroviruses, including the subgroups A, B, and C o

62 d lymphoid progenitors in the bone marrow of gammaretrovirus-infected animals and thereby contribute

63 quence, which reveals many past epidemics of gammaretrovirus infection, and from recent cross-species

64 likely arose in conjunction with exposure to gammaretrovirus infections and coevolutionary adaptation

65 intermediately inhibited Betaretrovirus and Gammaretrovirus infections yet was basically ineffective

66 genome displays a rich fossil record of past gammaretrovirus infections, yet no current epidemic is e

67 These results document the diversity in gammaretroviruses isolated from globally distributedMuss

68 s gPr80gag is evolutionarily conserved among gammaretroviruses, its mechanism of action has been uncl

69 d in human prostate cancers and is the first gammaretrovirus known to infect humans.

70 Although the endogenizing gammaretrovirus koala endogenous retrovirus (KoRV) was i

71 rovirus, Deltaretrovirus, Epsilonretrovirus, Gammaretrovirus, Lentivirus, and Spumavirus.

72 stem/progenitor cells compared to analogous gammaretrovirus/lentivirus vectors carrying the same enh

73 preference for nongenic regions compared to gammaretrovirus/lentivirus vectors.

74 er preference for nongenic integrations than gammaretroviruses/lentiviruses and preferential integrat

75 ial copackaging of homodimers in the case of gammaretroviruses, like murine leukemia virus (MLV), led

76 ine leukemia virus-related virus (XMRV) is a gammaretrovirus linked to prostate carcinoma and chronic

77 Infection with a recombinant murine-feline gammaretrovirus, MoFe2, or with the parent virus, Molone

78 ed HIV-1 infectivity, while infection by the gammaretrovirus Moloney murine leukemia virus (MLV) was

79 es of active genes, whereas the prototypical gammaretrovirus Moloney murine leukemia virus (MoMLV) fa

80 gh efficiency on virus replication using the gammaretrovirus MuLV as a model system.

81 that for cells chronically infected with the gammaretrovirus murine leukemia virus in which receptor

82 virus (FeLV) is a common naturally occurring gammaretrovirus of domestic cats that is associated with

83 ine leukemia virus-related virus (XMRV) is a gammaretrovirus originally identified in a subset of pro

84 CrERVgamma forms a distinct branch of the gammaretrovirus phylogeny, with the closest relatives of

85 Vs) are part of a larger group of pathogenic gammaretroviruses present across phylogenetically divers

86 ine leukemia virus-related virus (XMRV) is a gammaretrovirus recently isolated from human prostate ca

87 s due to a nonpermissive variant of the XPR1 gammaretrovirus receptor, a resistance that also limits

88 rovides a plausible explanation for why most gammaretrovirus recombinants, although relatively rare,

89 These gammaretroviruses rely on the XPR1 receptor for entry, a

90 are similar and reveal common principles of gammaretrovirus RNA genome packaging.

91 NA, but not RNA, containing novel endogenous gammaretrovirus sequences was detected in the JEV vaccin

92 cted as important overlooked facilitators of gammaretrovirus spread across diverse mammalian hosts.

93 Endogenous retroviruses (ERVs) of these 2 gammaretrovirus subtypes are largely segregated in diffe

94 on with FeLV.IMPORTANCE Domestic exposure to gammaretroviruses such as feline leukemia viruses (FeLVs

95 der of magnitude more frequently than simple gammaretroviruses such as murine leukemia virus and sple

96 Gammaretroviruses, such as murine leukemia virus (MLV),

97 sequence connecting the CA and NC domains in gammaretroviruses, such as murine leukemia virus (MLV),

98 For numerous gammaretroviruses, such as the gibbon ape leukemia virus

99 Members of the gammaretroviruses--such as murine leukemia viruses (MLVs

100 ent articles have reported the presence of a gammaretrovirus, termed "XMRV" (xenotropic murine leukem

101 urine leukemia virus-related virus (XMRV), a gammaretrovirus that can infect human cells.

102 emia virus (FeLV) is a naturally transmitted gammaretrovirus that infects domestic cats.

103 Gammaretroviruses that enter cells via binding to a surf

104 viruses (XMVs and PMVs) are closely related gammaretroviruses that use the XPR1 receptor for entry.

105 dify the MLV CA to resemble those from other gammaretroviruses, the deletion mutants produced virions

106 mized HIV-1 Gag-Pol and envelope proteins of gammaretroviruses; these producer cells could make up to

107 The data obtained indicate that gammaretroviruses tolerate a substantial excess of viral

108 In the gammaretroviruses, typified by Moloney murine leukemia v

109 Thus, our results demonstrate that gammaretroviruses use NXF1 for the cytoplasmic accumulat

110 ing that two essentially unrelated beta- and gammaretroviruses use similar mechanisms to escape inhib

111 tion with cells transduced with an identical gammaretrovirus vector backbone expressing methylguanine

112 Strong viral enhancers in gammaretrovirus vectors have caused cellular proto-oncog

113 mmunodeficiency virus type 1 (HIV-1) and the gammaretroviruses was previously reported, with the form

114 rine leukaemia virus-related virus (XMRV), a gammaretrovirus, was discovered in prostate cancer tumou

115 To extend this investigation to gammaretroviruses, we engineered a fluorescent Moloney m

116 In addition, we found that these gammaretroviruses were strongly (X-MLV) or partially (XM

117 KoRV represents a unique example of a gammaretrovirus whose envelope has evolved to allow for

118 experimental evidence that XMRV is indeed a gammaretrovirus with protein composition and particle ul

119 versifying selection were detected among the gammaretroviruses with concentration in the env gene acr

120 monstrated only for nontransmissible variant gammaretroviruses with recombinant and mutant envelope g

121 matitis Indiana virus (VSV), lentiviruses or gammaretroviruses with their envelope proteins replaced

122 A novel gammaretrovirus, xenotropic murine leukemia virus-relate

123 CFS patients, we identified DNA from a human gammaretrovirus, xenotropic murine leukemia virus-relate

124 l. reported an association between the human gammaretrovirus XMRV and chronic fatigue syndrome.