ライフサイエンスコーパス: ganglioside GM1

1 iation constant for cholera toxin binding to ganglioside GM1.

2 (CTB) and the corresponding membrane ligand, ganglioside GM1.

3 pic phase behavior, and their high levels of ganglioside GM1.

4 to the lipid raft-associated natural product ganglioside GM1.

5 nce of NANA in a LOS structure mimicking the ganglioside GM1.

6 ycero-3-phospho-l-serine (sodium salt)), and ganglioside GM1.

7 e dependent upon binding of the B subunit to ganglioside GM1.

8 bind GT1b, but bound specifically to another ganglioside, GM1.

9 Inasmuch as the anionic ganglioside GM1, a compound structurally dissimilar to a

10 derived from Escherichia coli that binds to ganglioside GM1, a glycosphingolipid on the surface of m

11 tested whether CT's apical membrane receptor ganglioside GM1 acts specifically in toxin action.

12 ) and an internally esterified derivative of ganglioside GM1 (AGF2) upon ethanol-induced changes in t

13 he thermotropic and structural properties of ganglioside GM1 alone and in a binary system with 1,2-di

14 ney were positive for the lipid raft markers ganglioside GM1 and Caveolin-1.

15 preferential localization of sphingomyelin, ganglioside GM1 and cholesterol in the monolayer region

16 ns and lipid rafts, however, examined mainly ganglioside GM1 and glycosylphosphatidylinositol-linked

17 The caveolar markers ganglioside GM1 and H-ras were found concentrated in the

18 CT and LTIIb distinguish between gangliosides GM1 and GD1a at the cell surface by virtue

19 particles, we demonstrate that both alpha2-3 gangliosides GM1 and GM3 are capable of mediating this i

20 n 6 inhibition decreased the delivery of GM1 ganglioside (GM1) and glycosylphosphatidylinositol (GPI)

21 ich specifically binds to the raft component ganglioside GM1, and an antibody against CTX.

22 XCR4 colocalized with raft-resident markers, ganglioside GM1, and glycosylphosphatidylinositol-anchor

23 toxin, with their natural GSL receptors, the ganglioside GM1, and the globotriaosylceramide Gb3, resp

24 cetylene lipid and the cell surface receptor ganglioside GM1 are utilized to construct an amperometri

25 labile enterotoxin from Escherichia coli and ganglioside GM1 as a paradigm, we developed a modeling p

26 virus simian virus 40 (SV40), which uses the ganglioside GM1 as a receptor that mediates cell binding

27 , CD9 and alpha(3) integrin colocalized with ganglioside GM1 as seen by double staining of fixed cell

28 The ganglioside GM1, as the recognition unit for cholera tox

29 Finally, the upregulation of caveolin-1 and ganglioside GM1 at the plasma membrane of E5-expressing

30 on in its B subunit, which binds in vitro to ganglioside GM1 but not to ganglioside GD1b, was unable

31 ipid analogs of glucosylceramide, sulfatide, ganglioside GM1, ceramide 1-phosphate, sphingosine 1-pho

32 The lipid raft marker, ganglioside GM1, co-localizes with CD44 on the plasma me

33 ed CFTR (GFP-CFTR) and the lipid raft marker ganglioside GM1 colocalized at sites of P. aeruginosa co

34 Patches of cross-linked raft resident ganglioside GM1 colocalized with ULBP1, 2, 3, or MICA, b

35 d that alpha-synuclein specifically binds to ganglioside GM1-containing small unilamellar vesicles (S

36 The mechanism(s) by which ganglioside GM1 functions in signal transduction likely

37 The ganglioside GM1 (Gal 1beta1, 3GalNAcbeta1, 4Gal-NeuAcalp

38 Here, the terminal sugar of ganglioside GM1, galactose, was chosen as a lead in desi

39 s gangliosides, and is selective for certain gangliosides (GM1, GD1a, and GD1b), whereas others (GM3)

40 Exogenous addition of mixed gangliosides (GM1, GD1a, and GT1b) as well as GD1a itsel

41 dies (mAbs) against the major nervous system gangliosides GM1, GD1a, GD1b and GT1b to test whether an

42 ide antisera, three monoclonal antibodies to ganglioside GM1 (GM1) and of the cholera toxin B subunit

43 sults revealed that CTB5 binds to six of the gangliosides (GM1, GM2, GM3, GD1a, GD1b, and GT1b), whil

44 nstrate the reliability of the method, seven gangliosides (GM1, GM2, GM3, GD1a, GD1b, GD2, and GT1b)

45 ientation relative to a membrane surface) of ganglioside GM1 in biologically relevant membrane enviro

46 e (Gal-T-II) is responsible for synthesis of ganglioside GM1 in the ganglioside biosynthetic pathway.

47 crosslinking a minor membrane component, the ganglioside GM1, in simple lipid models of the plasma me

48 We report that intraventricular infusion of ganglioside GM1 induces phosphorylation of mutant huntin

49 l-dependent cohesive phase separation of the ganglioside GM1 into nano- and microscale assemblies in

50 robe linked to the membrane-imbedded tail of ganglioside GM1 is not influenced by pH in a range from

51 The complex of cholera toxin and ganglioside GM1 is one of the highest affinity protein-c

52 Ganglioside GM1 is the natural receptor for cholera toxi

53 entavalent binding between cholera toxin and ganglioside GM1 is used as a model system to demonstrate

54 GM1-ganglioside (GM1) is a major sialoglycolipid of neuronal

55 ing antigen uptake because the CTB receptor, ganglioside GM1, is a glycolipid present in apical membr

56 icate that the expression of raft-associated ganglioside, GM1, is increased in T cells from SLE patie

57 covalently attached sugar molecules such as ganglioside GM1, lactosyl phosphatidylethanolamine, and

58 ination of a completed genome sequence and a ganglioside GM1-like LOS structure makes C. jejuni NCTC

59 n subunit B binding protein (BODIPY)-labeled ganglioside GM1 lipid after Fas-L induction of apoptosis

60 Results with positively curved lipids (ganglioside, GM1; lysophosphatidylcholine, LPCs) and neg

61 palmitoyl-sn-glycero-3-phosphocholine (DPPC)-ganglioside GM1 monolayers to probe Abeta-GM1 interactio

62 oth fluorescence donor and acceptor)-labeled ganglioside GM1 on a biomimetic membrane surface (suppor

63 These findings show that ganglioside GM1 on T84 cells is not a functional recepto

64 ra toxin causes diarrheal disease by binding ganglioside GM1 on the apical membrane of polarized inte

65 olocalization between IK1 and the lipid raft ganglioside GM1 on the plasma membrane, which subsequent

66 0-fold increase in the lipid raft component, ganglioside GM1, on the cell surface and mediates a dram

67 d when GM3 was absent or replaced with other gangliosides GM1 or GD1a, or with LacCer.

68 osphatidylinositol-linked protein Thy-1, the ganglioside GM1, palmitoylated LAT, and cross-linked IgE

69 Finally, nuclear membrane-associated ganglioside GM1 plays a pivotal role in Ca(2+) homeostas

70 luorescent dendriplexes co-localize with the ganglioside GM1 present into membrane rafts in both an i

71 lex of the cholera toxin B-pentamer with the ganglioside GM1 receptor pentasaccharide diffract to nea

72 n, the addition of increasing amounts of the ganglioside GM1 reduced the potency of the inhibitor dra

73 In early development, sterol efflux and the ganglioside GM1 regulate sperm acrosome exocytosis (AE)

74 several other oligosialogangliosides and to ganglioside GM1, the functional receptor for cholera tox

75 Ganglioside GM1, the receptor for CT, is predominantly c

76 of the cholera toxin B subunit, which binds ganglioside GM1, to the Golgi apparatus.

77 gulated localization of a lipid raft marker, ganglioside GM1, to the leading edge.

78 ays utilized a ganglioside-"capture" format: ganglioside GM1, utilized for capture of analyte, was im

79 t analysis showed that the "raft" associated ganglioside GM1 was enriched in the detergent-insoluble

80 Binding to ganglioside GM1 was essential for suppression, since rLT

81 The ganglioside GM1 was tagged with the fluorescent dye tetr

82 Ganglioside GM1 was used to prepare the liposomes by spo

83 esult in cDNA amplification when a different ganglioside (GM1) was used for coating of the microtiter

84 a (CTbeta), which binds to the raft-enriched ganglioside GM1, was selected to label rafts.

85 ilayers containing various concentrations of ganglioside GM1 were addressed along the length of indiv

86 resence of Nef, viral envelopes contain more ganglioside (GM1), which is a major component of lipid r

87 The natural receptor for LT is the complex ganglioside GM1, which has galactose as its terminal sug

88 nked proteins Thy-1 and CD59, as well as the ganglioside GM1, which is known to partition preferentia

89 Cross-linking of raft gangliosides GM1 with cholera toxin (CTxB) was shown to