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1 1b series (GT1b), but not by a non-1b series ganglioside (GM3).
2 with EGFR requires the presence of CD82 and ganglioside GM3.
3 nant ECD from insect cells bound directly to ganglioside GM3.
4 yed milder PKD, revealing a pivotal role for ganglioside GM3.
7 characterized by the predominant presence of ganglioside GM3 and adhere to lactosylceramide- or Gg3-c
8 its receptor (FGFR), stably associated with ganglioside GM3 and TSPs CD9 and CD81 in the ganglioside
9 osylceramide, globotriaosylceramide, and the gangliosides GM3 and GM1 were significantly elevated in
11 t out to address the role of a specific GSL (ganglioside GM3) and signaling SL (sphingosine-1-phospha
12 lysobisphosphatidic acid, sphingomyelin, the ganglioside GM3, and cholesterol esters, all of which su
13 tyrosine kinase is known to be inhibited by ganglioside GM3, but to a much lesser degree by other gl
14 A synthesis in a reversible manner, although ganglioside GM3 could not reverse the effects of FB1 on
16 found that caveolin-1, tetraspanin CD82, and ganglioside GM3 enable the association of EGFR with PKC-
17 morphology could be reversed by addition of ganglioside GM3 even in the presence of FB1, whereas the
18 ) we generated mice that express only simple gangliosides (GM3/GD3) and examined their central and pe
19 s including several sphingolipids (ceramide, ganglioside GM3, GM2, GM1, GD3 and GD1a), cardiolipin, c
20 ids, such as ceramide, glucosylceramide, and ganglioside GM3, have been implicated in various aspects
23 nd the chicken fibroblast cell line DF1, the ganglioside GM3 is the major glycosphingolipid component
24 te that kidney glucosylceramide (GlcCer) and ganglioside GM3 levels are higher in human and mouse PKD
26 eaction) as well as ceramide trihexoside and ganglioside GM3 (products distal to the GlcCer synthase
27 th the specificity of soluble ECD binding to gangliosides, GM3 specifically inhibited EGFR autophosph
28 ) L612, specific to a tumor-related antigen (ganglioside) GM3 that is expressed on the cell surface o
29 h FB1 resulted in a decrease in synthesis of ganglioside GM3, the major glycosphingolipid in 3T3 fibr
31 the sialidase-positive clones, the level of ganglioside GM3 was diminished, and little change was ob
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