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1 Mesoderm induction begins during gastrulation.
2 ity and cell blebbing, eventually abrogating gastrulation.
3 niche, and germ line commitment occurs after gastrulation.
4 rocess of apical constriction during Xenopus gastrulation.
5 in convergent extension movements in Xenopus gastrulation.
6 blastopore closure throughout the course of gastrulation.
7 ndent epiblast populations, specified before gastrulation.
8 constriction during Drosophila melanogaster gastrulation.
9 ession of individual cells start well before gastrulation.
10 y modulation and tissue morphogenesis during gastrulation.
11 (YSL) secretes a ventralizing signal during gastrulation.
12 stic and can form multiple individuals until gastrulation.
13 er emerging from the primitive streak during gastrulation.
14 rs of endoderm, mesoderm and ectoderm during gastrulation.
15 TGFbeta) signal expressed posteriorly before gastrulation.
16 s required for Wnt5b/Vangl2 signaling during gastrulation.
17 ment of mesendodermal cells during zebrafish gastrulation.
18 d more recently in cell intercalation during gastrulation.
19 tical role in C&E movements during zebrafish gastrulation.
20 ts, specified in the primitive streak during gastrulation.
21 organization of germ layers during mammalian gastrulation.
22 ed cell migration and cell morphology during gastrulation.
23 nt5b/Vangl2/Ror2 signaling during vertebrate gastrulation.
24 properties of the cellular blastoderm during gastrulation.
25 tructural stiffness of the blastopore during gastrulation.
26 particularly during the early stages before gastrulation.
27 formation dynamics diverge near the onset of gastrulation.
28 rning of DV tissues along the AP axis during gastrulation.
29 of approximately 1,000 mesoderm cells during gastrulation.
30 tion of a three-dimensional body plan during gastrulation.
31 of the ectoderm persists throughout much of gastrulation.
32 ts, and the Wnt antagonist iCRT14, following gastrulation.
33 the dynamic cellular events occurring during gastrulation.
34 onvergent and extension cell movement during gastrulation.
35 and protein are expressed from oogenesis to gastrulation.
36 to during the formation of mesoderm layer in gastrulation.
37 ipotent states, before lineage commitment at gastrulation.
38 ocytes, and to a developmental arrest during gastrulation.
39 this process, but is known to act only after gastrulation.
40 tion on expression levels of 205 genes up to gastrulation.
41 rvive through implantation but fail prior to gastrulation.
42 an inhibitor of Rho-kinase activity, prevent gastrulation.
43 eral displacement of Bazooka still occurs by gastrulation.
44 oposterior axis but fail to progress through gastrulation.
45 ed, basolateral displacement still occurs by gastrulation.
46 g convergent extension during Xenopus laevis gastrulation.
47 and mesodermal cell behaviors during Xenopus gastrulation.
48 cell movements and lineage induction during gastrulation.
49 tory genes during early frog development and gastrulation.
50 points to a simplified model for Drosophila gastrulation.
51 to the formation of the primitive streak and gastrulation.
52 r axial elongation of the mouse embryo after gastrulation.
53 against being caught up in the movements of gastrulation.
54 the embryo is severely altered during early gastrulation.
55 ryos null for Rala and Ralb do not live past gastrulation.
56 sults in embryonic lethality with failure of gastrulation.
57 ess than half of the genomes needed to reach gastrulation.
58 invagination of the mesoderm at the onset of gastrulation.
59 tes mesendoderm development during zebrafish gastrulation.
60 h post-fertilization, immediately following gastrulation.
61 of early mesoderm formation during mammalian gastrulation.
62 postpone EMT during Drosophila melanogaster gastrulation.
63 iated with pattern formation at the onset of gastrulation.
64 or Wnt signaling activation during embryonic gastrulation.
65 non-canonical Wnt pathways during vertebrate gastrulation.
66 d evolution of similar transitions in animal gastrulation.
67 hogenesis and papc expression during Xenopus gastrulation.
68 pluripotency protein Ventx2 at the onset of gastrulation.
69 arise from basal posterior progenitors after gastrulation.
70 spatiotemporal pattern starting during late gastrulation.
71 that drive initial cell shape changes during gastrulation.
72 the conditions for successful pregnancy and gastrulation.
73 internalization of the ventral furrow during gastrulation.
74 l, whose function is required for vertebrate gastrulation.
75 in pigment cells, and its inhibition impairs gastrulation.
76 during germ layer formation at the onset of gastrulation.
77 several aspects of embryogenesis, including gastrulation.
78 enous strain during a critical period around gastrulation.
79 f Smad2/3 binding and gene expression during gastrulation.
80 vergence and extension cell behaviors during gastrulation.
81 ibits the repression of lambda-olt 2-1 after gastrulation.
83 ene regulatory network (GRN) at the onset of gastrulation (24 h postfertilization) in N. vectensis Su
84 individual regulatory genes each hour up to gastrulation (30 h) in four different spatial domains of
87 utant embryos that fail to form cells before gastrulation ('acellular' embryos), such that the global
88 ation and t48, which in the evolution of fly gastrulation acted as a likely switch from an ingression
90 of dorsal transverse folds during Drosophila gastrulation, adherens junctions shift basally in the in
91 ry mesenchyme cells (PMCs) during sea urchin gastrulation, although the relative contributions of the
93 tors resulted in developmental arrest before gastrulation and a failure to activate >75% of zygotic g
94 fically in the epiblast are able to initiate gastrulation and advance to late primitive streak stages
95 mit CM number in zebrafish embryos: prior to gastrulation and after the initial wave of CM differenti
96 ed cell movements are crucial for vertebrate gastrulation and are controlled by multiple signals.
97 Basic body plans are organized by the end of gastrulation and are refined as limbs, organs, and nervo
99 remain receptive to extracellular cues after gastrulation and continue to make basic germ layer decis
103 s TRPM6 (XTRPM6) is elevated at the onset of gastrulation and is concentrated in the lateral mesoderm
104 the prospective neural crest epiblast during gastrulation and is unlikely to operate through mesoderm
105 yury (T, BRA) is one of the first markers of gastrulation and lineage specification in vertebrates.
109 phic imaging with a typical duration of 2 h (gastrulation and neurulation stages), intricacies of ima
110 pathway in endomesoderm specification during gastrulation and overall animal-vegetal patterning at ea
111 pp-a, one of the two paralogs, begins during gastrulation and persists throughout the first week of d
112 al or cellular defects, including failure of gastrulation and problems with placement and function of
113 of inductive interactions that begins before gastrulation and progressively divide embryonic ectoderm
120 he formation of the three germ layers during gastrulation and the differentiation of adult stem cells
121 delamination of mesendodermal precursors at gastrulation and the proper specification of the neural
122 epression of endogenous Bmp signaling during gastrulation and this enables mesodermal progenitors to
123 ers epithelial cell shape changes that drive gastrulation and tissue folding and is one of the most e
125 However, this strong coupling diminished at gastrulation and was absent in non-embryonic samples, in
126 derm-endoderm boundary is established before gastrulation, and ectodermal cells at the boundary are t
127 ion of the transcription factor Gata2 during gastrulation, and Gata2 is required in both ectodermal a
128 sed cell rearrangements in processes such as gastrulation, and has also been implicated in regulation
130 are expressed in a localized fashion by mid-gastrulation, and which thus provide spatial regulatory
131 r in many developmental processes, including gastrulation, anterior-posterior axis specification, org
133 a signaling pathway active during Drosophila gastrulation as a model system to study Ric-8/Galpha int
135 time is highest immediately before and after gastrulation, as well early in the segmentation period.
136 emerge as the cell cycle slows just prior to gastrulation at a major embryonic transition known as th
139 itially arises in the developing skin during gastrulation, based on the appearance of polarized apica
141 quires an inhibition of Wnt signals prior to gastrulation, but becomes insensitive during early gastr
142 tively along a fibronectin (FN) substrate at gastrulation, but how the adhesive and mechanical forces
143 epithelial-mesenchymal transition (EMT) and gastrulation, but its role in self-renewal, pluripotency
144 tinuing roles in Bazooka localization during gastrulation, but other polarity cues partially restore
145 els in cell aggregates and during vertebrate gastrulation, but the role of differential Cdh activity
146 ansfated from notochord to somite fate after gastrulation by ectopic expression of msgn1, a master re
147 cells and the elongating archenteron during gastrulation; Cadherin (G form) has an important role in
151 oderm undergo morphogenetic movements during gastrulation, cells in both germ layers read their posit
153 ctions with the extracellular proteins Short gastrulation/Chordin (Chd) and Twisted gastrulation (Tsg
154 xes, is required for normal morphogenesis at gastrulation, closure of the anterior neural tube, axial
155 Zic3 demonstrates an early role for Zic3 in gastrulation, CNS, cardiac and left-right axial developm
156 nt of left-right (LR) asymmetry occurs after gastrulation commences and utilizes a conserved cascade
157 anterior and visceral mesoderm precursors as gastrulation commences, and find that both Cytochalasin
158 three populations acts independently during gastrulation, confirming previous hypotheses that cell b
160 ing, required for hypochord induction during gastrulation, continues to act in the tailbud to specify
163 tion events occurring prior to completion of gastrulation coordinate the morphogenetic movements unde
164 cipates in noncanonical Wnt signaling during gastrulation, Daam2 function remains completely uncharac
165 s embryos was sufficient to fully rescue the gastrulation defect caused by loss of hepatocystin.
168 ltaN) mice were not viable, and several post-gastrulation defects revealed the first in vivo function
170 man heterotaxy phenotype but also have early gastrulation defects, axial patterning defects and neura
171 -1; miR-9a double mutant revealed defects in gastrulation, demonstrating the importance of co-activat
172 n and monkey in vitro models simulating peri-gastrulation development to show the conserved principle
173 inhibition of jagn just before the start of gastrulation disrupts this asymmetric division of the ER
175 m-like properties of the epiblast of the pre-gastrulation embryo and for cellular and physiological h
180 disrupts migration of the mesoderm after the gastrulation epithelial-to-mesenchymal transition (EMT).
181 rate a critical role for Cripto during mouse gastrulation, especially in mesoderm and endoderm format
184 s a model, we show that regulation of folded gastrulation expression by the Fork head transcription f
188 ssion in dorsal posterior cells during early gastrulation, focusing Wnt1 signaling to the posterior-v
189 three signaling pathways are required during gastrulation for the proper expression of pax3a and zic3
190 vely regulate each other's expression during gastrulation, forming a self-sustaining network that ope
191 Altogether, our data establish that during gastrulation, FOXF1 marks all posterior primitive streak
193 Historically, the position of the site of gastrulation has been used to understand the development
194 stically reducing the level of FGF8 later in gastrulation has no apparent effect on somitogenesis or
195 nd spreading of the animal hemisphere during gastrulation, here we provide evidence that radial inter
197 mplex epithelium in planula stages following gastrulation in addition to previously described roles f
198 ing critical morphogenetic events, including gastrulation in diverse organisms and neural tube closur
202 static and developmental contexts, including gastrulation in many organisms and neural tube formation
203 ates that mesoderm induction continues after gastrulation in neuromesodermal progenitors (NMPs) withi
205 ions that form two aggregations during early gastrulation in the crustacean Parhyale hawaiensis.
207 f a reprogramming capability occurs at early gastrulation in the sea urchin embryo and requires activ
208 rs systemically must be established prior to gastrulation in the very early embryo and, because it is
209 rotocol for applying this technique to study gastrulation in Xenopus laevis (African clawed frog) emb
210 rax transcription is initiated at the end of gastrulation in Xenopus, and is a key part of the regula
213 imelines and summarizes key stages following gastrulation, including endoderm patterning, organ speci
214 igration away from the primitive streak when gastrulation initiates, but previous studies have shown
217 enetically proving that Tcf3 function during gastrulation is independent of beta-catenin interaction.
218 ism in the early Drosophila embryo, in which gastrulation is preceded by 13 sequential nuclear cleava
219 a demonstrate that Alk4/5/7 signaling during gastrulation is required to direct PMCs to the oral hood
221 d that cell organization in the embryo until gastrulation is well described by a purely mechanical mo
223 Conditional inactivation of Cripto during gastrulation leads to varied defects in mesoderm and end
224 als its abnormal development at the onset of gastrulation, many hours before changes are obvious to t
225 te the position of the head and the onset of gastrulation, marked by T/Brachyury (T/Bra) at the poste
227 s, demonstrating that in the early stages of gastrulation most subapical clusters in mesoderm not onl
230 he source of this extrinsic force, we mapped gastrulation movements temporally using light sheet micr
231 he cytoplasmic tyrosine kinase Arg modulates gastrulation movements through control of actin remodeli
232 r of APJ/Apelin receptor signaling, promotes gastrulation movements, and might be the first in a seri
235 d convergence and extension movements during gastrulation, neurulation and epidermis defects and enha
238 lls gained the ability to reprogram early in gastrulation only after extended contact with the vegeta
240 layers that provide the structural basis for gastrulation or subsequent developmental events [1].
244 tion of all three Tet genes in mice leads to gastrulation phenotypes, including primitive streak patt
247 rk recapitulates these variable and bistable gastrulation profiles and emphasizes the importance of t
250 ypotheses that cell behavior during Parhyale gastrulation relies on intrinsic signals instead of an i
251 regulated switch to late replication during gastrulation, reminiscent of mammalian X Chromosome inac
252 ergent extension movements during vertebrate gastrulation require a balanced activity of non-canonica
253 t and its conditional ablation, beginning at gastrulation, results in increased apoptosis, growth ret
254 bition renders the concentration of dNTPs at gastrulation robust, with respect to large variations in
256 ulate cell polarity and intercalation during gastrulation, signaling molecules acting in other pathwa
257 , using enhancers of brinker (brk) and short gastrulation (sog), both of which are directly activated
260 t1 in mouse embryos causes death at the post-gastrulation stage; however, the functions of Dnmt1 and
264 ntration caused changes in cell movements at gastrulation that also altered the tissue fates of these
265 nase MRCK-1 as a key regulator of C. elegans gastrulation that integrates spatial and developmental p
266 te embryos undergo dramatic shape changes at gastrulation that require locally produced and anisotrop
267 ed population of cells emerges at the end of gastrulation that, under the influence of Wnt and FGF si
275 d CaN signaling opposes BMP signaling during gastrulation, thereby promoting neural induction and the
277 ng is required for mesoderm induction during gastrulation through positive transcriptional regulation
278 els in the embryo blocks force generation at gastrulation through two distinct mechanisms: destabiliz
279 entiation to mimic lineage commitment during gastrulation to ectoderm (early switch) or mesoderm/endo
286 n and random motility exhibited during early gastrulation were dependent on both Nodal and Rac1 signa
288 milar in both species until the beginning of gastrulation, when BMP signaling broadens and intensifie
289 of the three major germ layers occurs during gastrulation, when cells ingressing through the primitiv
290 ter is expressed throughout the embryo until gastrulation, when it becomes specifically expressed in
291 ipts differentially expressed by PMCs during gastrulation, when these cells undergo a striking sequen
294 t activation induces the neural crest during gastrulation, whereas activation of both pathways mainta
295 genes is also upregulated in males prior to gastrulation; whether it results in functional dosage co
296 Dynamic local methylation was evident during gastrulation, which enabled the identification of putati
297 ) axis elongation are fundamental aspects of gastrulation, which is initiated by formation of the pri
298 mits the developmental rate beginning during gastrulation without affecting the normal patterning of
299 ation (Tcf3(DeltaN/DeltaN)) progress through gastrulation without apparent defects, thus genetically
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