ライフサイエンスコーパス: gated

1 dicating that these permeants are distinctly gated.

2 This facilitative transport is ATP-gated.

3 We investigated whether motion correction of gated (18)F-fluoride PET/CT and PET/MRI of the aortic va

4 eutron stars, for which similar magnetically gated accretion cycles have been identified.

5 n turn implies the existence of magnetically gated accretion, in which disk material builds up around

6 by surface functional groups in a chemically gated-all-around configuration.

7 signal transmission through LAT is strongly gated and requires multiple phosphorylation events befor

8 in invertebrates, not affecting human ligand-gated anion channels.

9 ude for the full-length wild-type KcsA, a pH-gated bacterial channel, in membrane bilayers.

10 s provide a physical explanation for the ATP-gated behavior of SF2 RNA helicases and receptor protein

11 FapF forms a trimer of gated beta-barrel channels in which opening is regulated

12 ust sequence of even-denominator FQH in dual-gated BLG devices.

13 that motor cortical output in this period is gated by an inhibitory mechanism.

14 e (KCa2) calcium-activated K(+) channels are gated by calcium binding to calmodulin (CaM) molecules a

15 he yeast Pichia pastoris, is suggested to be gated by chemo-mechanical stimuli as a protective regula

16 s, this transfer is often slow because it is gated by diffusion-limited collisions between sensitizer

17 n integration of convergent cortical inputs, gated by GABAergic circuits.

18 ubunits are predicted to form anion channels gated by gamma-aminobutyric acid (GABA), glutamate, hist

19 Other medicinally important ion channels, gated by glutamate, gamma-aminobutyric acid (GABA), and

20 egans SLO-2, a high-conductance K(+) channel gated by membrane voltage and cytosolic Cl(-) and Ca(2+)

21 of the TRPN subfamily, and is thought to be gated by tethering of its ankyrin repeat domain to micro

22 o benefit from prolonged exposure in PTSD is gated by the degree to which prefrontal resources are sp

23 Gated by the neurotransmitter glutamate, AMPA receptors

24 eation of Slo2 channels is not predominantly gated by the S6 bundle crossing.

25 sory stereocilia of inner ear hair cells are gated by the tension of 'tip links' interconnecting ster

26 gest that slow modes of repuckering dynamics gated by transient changes in secondary structure are qu

27 malian Slo1, a high-conductance K(+) channel gated by voltage and Ca(2+).

28 cone, which is mainly controlled by voltage-gated Ca(2+) (Cav) and K(+) (Kv) channels, modulates axo

29 Voltage-gated Ca(2+) (CaV) channels consist of a pore-forming al

30 tested the hypothesis that different voltage-gated Ca(2+) channel densities in presynaptic active zon

31 ar cells by aligning the presynaptic voltage-gated Ca(2+) channel directing glutamate release (CaV1.4

32 get cell type-specific modulation of voltage-gated Ca(2+) channel function or different subunit compo

33 975A and GSK5498A) as well as L-type voltage-gated Ca(2+) channel inhibitors (nifedipine and nimodipi

34 hat is not conserved in CaV2 or CaV3 voltage-gated Ca(2+) channel subunits.

35 epends on Ca(2+) influx through high voltage-gated Ca(2+) channels (HVCCs).

36 ore-operated calcium entry (SOCE) or voltage-gated Ca(2+) channels (VGCCs), we show that SOCE, rather

37 through the dendritic high-threshold voltage-gated Ca(2+) channels activates CaCCs, which contribute

38 o activated by Ca(2+) influx through voltage-gated Ca(2+) channels and synaptically activated NMDA re

39 linated axons.SIGNIFICANCE STATEMENT Voltage-gated Ca(2+) channels are fulcrums of neurotransmission

40 Extracellular Ca(2+) via voltage-gated Ca(2+) channels established a Ca(2+)-dependent loc

41 depolarization increases to activate voltage-gated Ca(2+) channels in the adjacent vascular smooth mu

42 tivation of heterologously expressed voltage-gated Ca(2+) channels of type 1.3 (CaV1.3) and is defect

43 contributions of store-operated and voltage-gated Ca(2+) channels to this Ca(2+) influx, we generate

44 It is generally accepted that voltage-gated Ca(2+) channels, CaV, regulate Ca(2+) homeostasis

45 iggered by Ca(2+) influx from L-type voltage-gated Ca(2+) channels, not postsynaptic NMDA receptors (

46 educed spike-evoked Ca(2+) entry and voltage-gated Ca(2+) currents.

47 demyelinated brain and suggest that voltage-gated Ca(2+) influx in OPCs is critical for remyelinatio

48 on, by varying Ca(2+) influx through voltage-gated Ca(2+)-channels or Ca(2+) uncaging.

49 Recombinant voltage-gated calcium (Ca(2+)) channels in heterologous expressi

50 tivated calcium modulator 1 but also voltage-gated calcium channel (Cav) 1 channels.

51 coding exon (exon 47) of the Cav2.1 voltage-gated calcium channel (VGCC) gene produces two major iso

52 Here we show that the voltage-gated calcium channel CaV1.3 and the big conductance cal

53 the alpha1A subunit of the P/Q-type voltage-gated calcium channel Cav2.1.

54 Here, we recorded the voltage-gated calcium channel current in nucleated patches from

55 parison subjects as well as aberrant voltage-gated calcium channel subunit protein expression linked

56 a reduction in cacophony, a Type II voltage-gated calcium channel, expression and that genetically r

57 he ryanodine receptor but not in the voltage-gated calcium channel, indicating that these phenotypes

58 L-type voltage-gated calcium channels (LTCCs) are implicated in several

59 n NMDA receptors (nmdaLTP) or L-type voltage-gated calcium channels (vdccLTP).

60 to Gbetagamma-mediated modulation of voltage-gated calcium channels (VGCC), inhibition can also be me

61 udes oscillatory calcium signals via voltage-gated calcium channels as a key component.

62 their implications, with a focus on voltage-gated calcium channels as part of the disease process an

63 -channel current amplitude of native voltage-gated calcium channels can be resolved accurately despit

64 2 (mGluR2) signaling, which acts on voltage-gated calcium channels in SACs, selectively restricts cr

65 for estimating numbers of functional voltage-gated calcium channels in the membrane and the size of c

66 hippocalcin, mostly driven by N-type voltage-gated calcium channels.

67 This is the case for voltage-gated calcium channels.

68 ns that can bind and modulate L-type voltage-gated calcium channels.

69 alcium-dependent manner and binds to voltage-gated calcium channels.

70 nsient opening of different types of voltage-gated calcium channels.

71 STRACT: Several studies suggest that voltage-gated calcium currents are involved in generating high f

72 The voltage-gated cardiac Na(+) channel (Nav1.5), encoded by the SCN

73 Cngb1 locus-encoded beta-subunit of rod cGMP-gated cation channel and associated glutamic acid rich p

74 ens and forms a pore complex with the ligand-gated cation channel P2X7, allowing the release of excit

75 ting currents is well documented for voltage-gated cation channels (VGCC), and it is considered a vol

76 ier that operates downstream from cyclic GMP-gated cation channels and distal guanylate cyclases.

77 he mode-shift displayed by hyperpolarization-gated cation channels is likely caused by structural cha

78 or changes in pH, and three are putative ACh-gated cation channels.

79 thyl-d-aspartate (NMDA) receptors are ligand-gated, cation-selective channels that mediate a slow com

80 Voltage-gated Cav1.2 and Cav1.3 (L-type) Ca(2+) channels regulat

81 L-type voltage-gated CaV1.2 calcium channels (CaV1.2) are key regulator

82 tes Ca(2+)-dependent facilitation of voltage-gated Cav1.3 Ca(2+) channels in transfected cells.

83 Voltage-gated CaV2.1 channels comprise a pore-forming alpha1A su

84 Cyclic nucleotide-gated channel (CNGC) family members mediate Ca(2+) influ

85 yperpolarization-activated cyclic nucleotide gated channel 4), and the corresponding ionic current, I

86 dulations by acting through an acetylcholine-gated channel and a muscarinic acetylcholine receptor, r

87 from mutations in the KCNE2-encoded voltage-gated channel beta-subunit, is limited.

88 -microscopy structure of a cyclic-nucleotide-gated channel from Caenorhabditis elegans in the cyclic

89 These light-gated channel proteins of microbial origin are of intere

90 a-cells in mouse islets expressing the light-gated channelrhodopsin-2 resulted in stimulation of elec

91 cAMP opens cyclic nucleotide-gated channels allowing a Ca(2+) influx that opens Ca(2+

92 ies on cyclic guanosine monophosphate (cGMP)-gated channels and activity of the ASJ, AWB, and AWC neu

93 ating and channelopathy of cyclic-nucleotide-gated channels and cyclic nucleotide modulation of relat

94 Cyclic-nucleotide-gated channels are essential for vision and olfaction.

95 e plasma membrane and inositol trisphosphate-gated channels in the endoplasmic reticulum both signal

96 Ca(2+) entry through voltage-gated channels only becomes important when the cell is d

97 (NMDA) receptors are glutamate- and glycine-gated channels that flux Na(+) and Ca(2+) into postsynap

98 d that this small molecule influences ligand-gated channels, including the GABAA receptor and others.

99 ression depends on calcium entry via voltage-gated channels, is blocked by BAPTA chelation, and recru

100 larization-activated cyclic nucleotide (HCN)-gated channels.

101 ocalizing chimeras are also functional light-gated channels.

102 Activation of the glutamate-gated chloride channel expressed in either rodent or hum

103 ry marker ATF3 following prolonged glutamate-gated chloride channel expression.

104 ptor in a living cell, utilizing a glutamate-gated chloride channel from the nematode Haemonchus cont

105 Here we show that a glutamate-gated chloride channel modified to be activated by low d

106 rus serotype 9-based delivery, the glutamate-gated chloride channel was successfully targeted to mous

107 arises from selectively activating glutamate-gated chloride channels (GluCls) in invertebrates, not a

108 best described for its activity on glutamate-gated chloride channels in parasitic nematodes, understa

109 sion via the allosteric modulation of ligand-gated chloride channels, such as hetero-oligomeric alpha

110 n the CLCNKB gene encoding the human voltage-gated chloride ClC-Kb (hClC-Kb) channel cause classic Ba

111 brane conductance regulator (CFTR) is an ATP-gated Cl(-) channel defective in the genetic disease cys

112 Cyclic nucleotide-gated (CNG) and hyperpolarization-activated cyclic nucle

113 onse through the olfactory cyclic nucleotide-gated (CNG) channel and stimulates a depolarizing chlori

114 In contrast, the cyclic nucleotide-gated (CNG) channel inhibitor l-cis-diltiazem, as well a

115 found that cAMP activates cyclic nucleotide-gated (CNG) channels and thereby induces a Ca(2+) influx

116 lustrate how membrane properties and voltage-gated conductances can extract distinct stimulus feature

117 ynaptic inputs, so cells with larger voltage-gated conductances prefer higher frequencies.

118 uencies, due to differences in their voltage-gated conductances.

119 sibly reduce the sensitivity of mechanically gated currents in sensory neurons and silence mechanorec

120 We show that time-gated detection of millisecond-scale Tb(III) emission in

121 This effect is observed in dual-gated devices of bulk-insulating Bi2-x Sb x Te3 thin fil

122 activation of RhoA using the CRY2/CIBN light-gated dimerizer system.

123 to the ECG QRS complex to calculate the QRS-gated DPD (diastolic pulmonary artery pressure-QRS-gated

124 Cases reclassified as Cpc-PH based on QRS-gated DPD demonstrated higher pulmonary arterial pressur

125 The QRS-gated DPD reclassifies a subset of PH-LHD patients from

126 Within PH-LHD, the QRS-gated DPD yielded higher calculated DPD values (3 [-1 to

127 l-D-aspartate (NMDA) receptors are glutamate-gated excitatory channels that play essential roles in b

128 injection from the source electrode in back-gated field effect transistors.

129 Top-gated field-effect transistors based on Bi2O2Se crystals

130 We present iTango, a light- and ligand-gated gene expression system based on a light-inducible

131 a range of poorly understood experiments in gated graphene structures at low doping.Two-dimensional

132 neously exploits the pH dependency of liquid-gated graphene-based transistors and the change in the l

133 oswitch efficiency, and generate seven light-gated group II/III mGluRs, including variants of mGluR2,

134 perpolarization-activated, cyclic nucleotide-gated (HCN) channels play in this nociceptive sensitizat

135 yperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate excitability in neurons, a

136 yperpolarization-activated cyclic nucleotide-gated (HCN) channels, and contributes to depolarizing th

137 yperpolarization-activated cyclic nucleotide-gated (HCN) channels.

138 yperpolarization-activated cyclic nucleotide-gated (HCN) ion channels, alters both the cell surface e

139 yperpolarization-activated cyclic nucleotide-gated (HCN1) channels are predominantly located in pyram

140 iac troponin I using electrical double layer gated high field AlGaN/GaN HEMT biosensor.

141 e with quantitative microperfusion data from gated human foot microvasculature.

142 Functional assessment of gated individual dermal microvessels is therefore of out

143 o-diode array and the other system on a time-gated, intensified camera.

144 ctly inhibit neurons by activating G protein-gated inwardly rectifying K(+) (GIRK) channels, thereby

145 G protein-gated inwardly rectifying K(+) (GIRK/Kir3) channels medi

146 e monolayers expressing a depolarizing light-gated ion channel (Ca(2+)-translocating channelrhodopsin

147 These dimeric voltage-gated ion channel (VGIC) superfamily members have a uniq

148 py Torpedo model; the only pentameric ligand-gated ion channel imaged in a native lipid membrane.

149 yperpolarization-activated cyclic nucleotide-gated ion channel rescues the muscle phenotype and the n

150 They belong to the voltage-gated ion channel superfamily but their activities are c

151 ABAARs) are members of the pentameric ligand-gated ion channel superfamily.

152 t Receptor Potential A 1 (TRPA1) is a ligand-gated ion channel that contributes to inflammatory mecha

153 ow that G2A activation sensitizes the ligand-gated ion channel TRPV1 in sensory neurons via activatio

154 This study provides an example of a ligand-gated ion channel whose deactivation is sensitive to ago

155 s display at least two types of mechanically gated ion channel: normal mechanotransducer (MT) channel

156 rystal structure within this class of ligand-gated ion channels (LGICs).

157 Pentameric ligand-gated ion channels (pLGICs) mediate fast chemical signal

158 ceptors (NMDARs) are Ca(2+)-permeant, ligand-gated ion channels activated by the excitatory neurotran

159 s) belong to the family of pentameric ligand-gated ion channels and mediate fast excitatory transmiss

160 It has been proposed that mechanically gated ion channels are of functional importance in chond

161 Allosteric modulators of ligand-gated ion channels are of particular interest as therape

162 Allosteric modulators of pentameric ligand-gated ion channels are thought to act on elements of the

163 assigned 2378 models of voltage- and calcium-gated ion channels coded in NEURON to 211 clusters.

164 Pentameric ligand-gated ion channels control synaptic neurotransmission by

165 cine receptors (GlyRs) are inhibitory ligand-gated ion channels expressed in nerves of the spinal dor

166 Modulators of transmitter-gated ion channels have a wide range of maximal effects

167 ntly, major principles of function for light-gated ion channels have been elucidated by creating chan

168 Rather, it is mediated by voltage-gated ion channels in the cone membrane and acts by chan

169 The sensitivity of Piezo mechanically gated ion channels is controlled by stomatin-like protei

170 Desensitization in pentameric ligand-gated ion channels plays an important role in regulating

171 Channelrhodopsins (ChRs) are light-gated ion channels widely used for activating selected c

172 principles governing the operation of light-gated ion channels, but also enabled the creation of new

173 us studies have focused on pentameric ligand-gated ion channels, the details of anesthetic binding an

174 Similar to other ligand-gated ion channels, their gating cycle begins with trans

175 receptors, which are Cl(-)-permeable, ligand-gated ion channels.

176 s reminiscent of an omega current in voltage-gated ion channels.

177 for channel gating in all pentameric ligand-gated ion channels.

178 on for analyzing the behavior of transmitter-gated ion channels.

179 naptic transmission by functioning as ligand-gated ion channels.

180 study and modeling of the electron-transfer gated ion transport processes in carbon nanopipets.

181 A number of voltage-gated ionic currents can contribute to the generation or

182 tentials by activation of voltage and Ca(2+) gated K channels.

183 l blocker, and by 4-aminopyridine, a voltage-gated K(+) (KV) channel blocker.

184 Voltage-gated K(+) (Kv) channels are key factors in controlling

185 Heterotetramer voltage-gated K(+) (KV) channels KV2.1/KV6.4 display a gating ch

186 te expression of gene transcripts, G-protein gated K(+) channel (Kir3) and KATP (Kir6) currents were

187 The voltage-gated K(+) channel Kv2.1 has been intimately linked with

188 ar methods to determine how Kv3.4, a voltage-gated K(+) channel robustly expressed in dorsal root gan

189 In voltage-gated K(+) channels and the prokaryotic KcsA channel, co

190 On the other hand, numerous ligand-gated K(+) channels lack such gate, suggesting that they

191 KCNE3 (MiRP2) forms heteromeric voltage-gated K(+) channels with the skeletal muscle-expressed K

192 with and modulate the properties of voltage-gated K(+) channels.

193 insic membrane properties, enhancing voltage-gated K(+) currents and increasing intracellular Ca(2+)

194 d by an increase in the amplitude of voltage-gated K(+) currents.

195 unction or a gain-of-function of the voltage-gated K+ channel Kv1.2, were described to cause a new mo

196 citability through the activation of voltage-gated KCNQ2-5 potassium channels.

197 Voltage-gated Kv1.3 and Ca(2+)-dependent KCa3.1 are the most pre

198 cated in E-T coupling, activation of voltage-gated L-type Ca(2+) channels (LTCCs) in the plasma membr

199 Ca(2+) influx through voltage-gated L-type Ca(2+) channels (LTCCs), in particular Cav1

200 , which then pathologically recruits voltage-gated l-type Ca(2+) channels that synergize with GluN2A-

201 Ca2+ entry through voltage-gated L-type Ca2+ channels triggers exocytosis of insuli

202 Voltage-gated L-type CaV1.2 channels in cardiomyocytes exist as

203 Voltage-gated L-type CaV1.2 channels in cardiomyocytes exist as

204 The question of how mechanically gated membrane channels open and close is notoriously di

205 materials such as tunable molecular sieves, gated membranes and controlled-release nanocontainers.

206 LIP protein tags to create a family of light-gated metabotropic glutamate receptors (mGluRs).

207 have been prepared and investigated as redox-gated molecular rotors.

208 ine electrophysiological evaluation, cardiac gated multi-row computed tomographic imaging for beam de

209 vo gain-of-function mutations in the voltage-gated Na channel Nav1.6.

210 Voltage-gated Na(+) (NaV) channels are key regulators of myocard

211 The requirement of voltage-gated Na(+) and Ca(2+) channel activation indicates that

212 e we introduce roNaV2, an engineered voltage-gated Na(+) channel harboring a selenocysteine in its in

213 Thus, influx of Na(+) via voltage-gated Na(+) channels (NaV ) has emerged as an important

214 Voltage-gated Na(+) channels (Nav ) modulate neuronal excitabili

215 BTX targets voltage-gated Na(+) channels and enables them to open persistent

216 Acid-sensing ion channels (ASICs) are proton-gated Na(+) channels that are expressed throughout the n

217 ends on the gating rates of the fast voltage-gated Na(+) current.

218 electrolyte mixtures (KCl + CaCl2) through a gated nanofluidic device was performed.

219 multimolecular complexes composed of voltage-gated Nav and Kv7 channels associated with cell adhesion

220 e To assess the clinical feasibility of self-gated non-contrast-enhanced functional lung (SENCEFUL) m

221 The P2X7 receptor (P2X7R) is an ATP-gated nonselective cation channel that induces inflammat

222 hannel heterologous expressed in oocytes was gated open by extracellular sulfate.

223 label-free immunosensor based on electrolyte-gated organic field-effect transistor (EGOFET) was devel

224 A (BPA) immunoassay based on an electrolyte-gated organic field-effect transistor whose organic semi

225 ng a simple mechanism by which hydraulically gated oscillations can regulate size.

226 Secondary, gated outcomes included new and worsened radiographic ve

227 Claudin-2 forms gated paracellular channels and allows sodium ions and o

228 DPD (diastolic pulmonary artery pressure-QRS-gated PAWP).

229 rincipal interface between the intramembrane-gated pore and the cytoplasmic gating ring of the channe

230 ing subunits which resemble metazoan voltage-gated potassium (Kv1-Kv4) channels in assembly and gatin

231 Voltage-gated potassium 7.1 (Kv7.1) channel and KCNE1 protein co

232 died on the surface of the soma: the voltage-gated potassium and sodium channels Kv1.4 and Nav1.6 and

233 resonance imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-mediated

234 nst the extracellular domains of the voltage-gated potassium channel (VGKC) complex proteins, leucine

235 fine antigenic components within the voltage-gated potassium channel (VGKC) complex.

236 ents (6.3%): 3 (2.7%) had TPO-Ab and voltage-gated potassium channel complex (VGKCc) Ab, 2 (1.8%) had

237 editing in transcripts encoding the voltage-gated potassium channel Kv1.1 converts an isoleucine to

238 ditions treatable by blockade of the voltage-gated potassium channel Kv1.3.

239 s attributable to interdependence of voltage-gated potassium channel properties.

240 The voltage-gated potassium channel subfamily A member 3 (Kv1.3) dom

241 Kv11.1 (hERG) is a voltage-gated potassium channel that shows very slow ionic curre

242 I1-IgG-positive specimens had higher voltage-gated potassium channel-IgG immunoprecipitation values (

243 ed potassium (BK) channels and Kv3.3 voltage-gated potassium channels accompanies the inability of Pu

244 EAG-like (ELK) voltage-gated potassium channels are abundantly expressed in the

245 Kv3.1 and Kv3.2 voltage-gated potassium channels are expressed on parvalbumin-po

246 Voltage-gated potassium channels formed by KCNQ2 and KCNQ3 are e

247 ecific subclasses of voltage- and/or calcium-gated potassium channels may provide an important approa

248 v2.2)- and calcium (Kcnma1, Kcnn1 and Kcnn2)-gated potassium channels observed in the NAc of nonaddic

249 Voltage-gated potassium channels of the KCNQ (Kv7) subfamily are

250 great insight into the mechanism of voltage-gated processes but has been challenging to study experi

251 ns in previously unreported HVCN1, a voltage-gated proton channel-encoding gene and B-cell receptor s

252 constructed from a proton-switchable edge-on gated pyridinoparacyclophane unit with a light-switchabl

253 xplain sub-threshold characteristics of back-gated Schottky barrier FETs (SB-FETs) from 2D channel ma

254 n within a month, resulting in rapid voltage-gated sodium (NaV) channel and betaIV spectrin loss with

255 This voltage-gated sodium (Nav) channel subtype also plays an importa

256 Voltage-gated sodium (NaV) channels are essential for the transm

257 Voltage-gated sodium (NaV) channels are responsible for the init

258 Voltage-gated sodium (Nav) channels play a key role in generatin

259 Voltage-gated sodium channel (NaV) mutations cause genetic pain

260 RET) between the rat skeletal muscle voltage-gated sodium channel (Nav1.4) and fluorescently labeled

261 Gain-of-function mutations in the voltage-gated sodium channel (Nav1.5) are associated with the lo

262 ing genotyping and sequencing of the voltage gated sodium channel (VGSC) gene did not detect the comm

263 Veratridine (VTD) is a voltage-gated sodium channel (VGSC) modifier that is used as an

264 Voltage-gated sodium channel (VGSC) mutations cause severe epile

265 The voltage-gated sodium channel 1.7 (Nav1.7) plays an important rol

266 However, expression analysis of voltage-gated sodium channel alpha subunits revealed NaV 1.7 mRN

267 ted conformational cycle in a single voltage-gated sodium channel and give insight into the structura

268 quinquefasciatus display CNV for the voltage-gated sodium channel gene (Vgsc), target-site of pyrethr

269 s-of-function mutations in the brain voltage-gated sodium channel gene SCN1A.

270 by de novo missense mutations in the voltage-gated sodium channel gene SCN8A Here, we investigated th

271 ve been associated with mutations in voltage-gated sodium channel genes.

272 The Nav1.1 voltage-gated sodium channel is a critical contributor to excita

273 ABSTRACT: Voltage-gated sodium channel NaV 1.7 is required for acute and i

274 ations in SCN2A, a gene encoding the voltage-gated sodium channel Nav1.2, have been associated with a

275 t the expression and function of the voltage-gated sodium channel Nav1.7 are increased in a preclinic

276 genetic studies have implicated the voltage-gated sodium channel NaV1.7 as a therapeutic target for

277 Specifically, voltage-gated sodium channel subtype NaV 1.7 is required for sen

278 ce has clearly demonstrated that the voltage-gated sodium channel, Nav1.7, is critical to pain sensat

279 Bacterial voltage-gated sodium channels (BacNavs) serve as models of their

280 We examined the repertoire of voltage-gated sodium channels (NaV) in fluorescence-sorted mouse

281 other vertebrates, target conserved voltage-gated sodium channels (NaV) of nerve and muscle, causing

282 on, the thermal random motion of the voltage-gated sodium channels (Nav), which are bound to ankyrin

283 Voltage-gated sodium channels (Navs) play crucial roles in excit

284 Voltage-gated sodium channels (Navs) play essential roles in exc

285 shorter than the activation time of voltage-gated sodium channels (VGSC) would evoke action potentia

286 KCNQ2/3 (Kv7.2/7.3) channels and voltage-gated sodium channels (VGSCs) are enriched in the axon i

287 nd propagated by a single isoform of voltage gated sodium channels - SCN5A.

288 ot through NMDA receptors or through voltage-gated sodium channels and that the spine neck is not a s

289 ABSTRACT: Voltage-gated sodium channels are critical for neuronal activity

290 Fast opening and closing of voltage-gated sodium channels are crucial for proper propagation

291 ing Schwann cells, such as clustered voltage-gated sodium channels at the node of Ranvier and Shaker-

292 nt for exon 1b, PV interneurons lack voltage-gated sodium channels at their axonal initial segments a

293 duction in the fraction of available voltage-gated sodium channels due to insufficient recovery from

294 from entry through NMDA receptors or voltage-gated sodium channels.

295 Comparing top- and strain-gated structures, we find a 58% increase in electron mob

296 iments where the temperature is modulated in gated structures.

297 This oxidation potential-gated technology is amenable to endogenous peptides and

298 tride (TiN) film, which is incorporated in a gated TiN/SiO2/Ag plasmonic heterostructure.

299 Within the same intervals, PAWP was measured gated to the ECG QRS complex to calculate the QRS-gated

300 n of the self-defense response, freezing, is gated via oxytocin acting in the centro-lateral amygdala