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1 st sensory encoding in dlPFC is contextually gated.
2 ila melanogaster larvae expressing the light-gated activator CsChrimson and the inhibitor GtACR2 with
3 urrent physiological state with hypothalamus-gated amygdala inputs that signal upcoming ingestion of
5 cterium thermoautotrophicum-a purely calcium-gated and inactivating channel-in a lipid environment.
6 o the allosteric gating and regulation of CN-gated and nucleotide-modulated channels and CNG channel-
9 e, whose necked aperture to the cytoplasm is gated by a 12-fold symmetric, 35-nm diameter "crown" com
10 fficking during homeostatic upscaling can be gated by a single phosphorylation site on the GluA2 subu
16 MDA) receptors are Ca(2+)-permeable channels gated by glutamate and glycine that are essential for ce
20 the human siesta, is a "hard-wired" property gated by specific neurons of the master clock to favor s
23 ic plants, environmental signals are locally gated by the presence of developing fruits initiated in
26 mation processing units that rely on voltage-gated Ca(2+) (Ca(v)) channels to trigger Ca(2+)-dependen
27 the circadian regulation of distinct voltage-gated Ca(2+) channel (VGCC) components has not been comp
28 sts for the pharmacoresistant R-type voltage-gated Ca(2+) channel (VGCC) to be involved in transretin
29 ly, highlighted roles for the L-type voltage-gated Ca(2+) channel Ca(V)1.2 in nonexcitable cells.
31 al models had suggested that several voltage-gated Ca(2+) channels (VGCCs) regulated critical signali
35 microenvironment of the presynaptic voltage gated Ca(2+) channels revealed that alkalinization also
36 r understanding of the properties of voltage-gated Ca(2+) channels that support their presynaptic fun
37 erall increased expression of L-type voltage-gated Ca(2+) channels that, at presynaptic terminals, ab
39 that regulate SCN firing, including voltage-gated Ca(2+) currents, but the circadian regulation of d
40 ases.SIGNIFICANCE STATEMENT Reducing voltage-gated Ca(2+) influx in astrocytes during brain demyelina
41 ; and that attenuation of astrocytic voltage-gated Ca(2+) influx may be an effective therapy to reduc
43 tostella vectensis use a specialized voltage-gated calcium channel (nCa(V)) to distinguish salient se
45 gy in bystander neurons, as were the voltage-gated calcium channel Cacophony (Cac) and the mitogen-ac
46 es demonstrated that the anti-L-type voltage-gated calcium channel immunoglobulin G purified from pat
49 armacological manipulation of L-type voltage-gated calcium channels (VGCCs) and purinoceptors induced
50 MDA-type glutamate receptors but not voltage-gated calcium channels (VGCCs), and can also be observed
51 were mediated, in part, by dendritic voltage-gated calcium channels (VGCCs): pharmacological manipula
52 deletions in the significant set of voltage-gated calcium channels among CNVs called from both exome
53 AP) waveform controls the opening of voltage-gated calcium channels and contributes to the driving fo
54 econditioning was mediated by L-type voltage-gated calcium channels and is consistent with computatio
55 We have studied the regulation of voltage-gated calcium channels by MDIMP, which disrupts excitati
56 renal autoregulation mechanisms and voltage-gated calcium channels can maintain overall renal blood
57 (2020) demonstrate that Ca(v)2-type voltage-gated calcium channels do not mediate presynaptic assemb
58 und that the alpha2delta2 subunit of voltage-gated calcium channels negatively regulates axon growth
59 y unknown endogenous activator of the ligand-gated calcium channels transient receptor potential V1 a
61 n each compartment were dependent on voltage-gated calcium channels, and somatic and nuclear calcium
62 ation including glutamate receptors, voltage-gated calcium channels, the dopamine D2 receptor, and co
69 hysiological relevance in control of voltage-gated calcium influx and calcium-dependent cellular func
70 the P2X purinergic receptor family of ligand-gated cation channels and has recently been shown to reg
72 Acid-sensing ion channels (ASICs) are proton-gated cation channels that contribute to neurotransmissi
73 yperpolarization-activated cyclic nucleotide-gated channel (HCN) conductance in the afferent and crea
76 polarization-activated and cyclic nucleotide-gated channel HCN2 in the family of so-called pacemaker
77 etastable protein possesses superior voltage-gated channel regulation, efficient mitochondrial target
78 Gene expression of KCNA5 (potassium voltage-gated channel subfamily A member 5; encoding Kv1.5) was
79 4 palmitoylates the Shaker-like K(+) voltage-gated channel subunit (Kv1.1), thereby regulating Kv1.1
80 rom the receptor guanylate cyclase to a cGMP-gated channel that serves as a perfect chemo-electrical
82 ution of Na(+)-selective four-domain voltage-gated channels (4D-Na(v)s) in animals allowed rapid Na(+
83 encode single-domain Na(+)-selective voltage-gated channels (BacNa(v)), they typically exhibit much s
85 framework for understanding gating in ligand-gated channels and how mutations in the acetylcholine re
88 Recent advances of plant cyclic nucleotide-gated channels give new insight into their molecular fun
90 transducin that sensitizes cyclic nucleotide gated channels to cGMP and causes photoreceptor cell dea
91 yperpolarization-activated cyclic nucleotide-gated channels(5), and may represent an unexpected link
93 yperpolarization-activated cyclic nucleotide-gated channels, and from ATP-dependent pumping of Ca(2+)
95 ducing the generation potentials and voltage-gated channels, translating the generation potentials in
97 indicate that Hodor is a pH-sensitive, zinc-gated chloride channel that mediates a previously unreco
98 glutamate transporter and also as glutamate-gated chloride channel, the chloride conductance being l
99 e positive allosteric modulator of glutamate-gated chloride channels found in nematodes and insects.
101 egalovirus (HCMV) and identified the voltage-gated chloride ion channel inhibitor 4,4'-diisothiocyano
102 both Brugia osm-9 and the cyclic nucleotide-gated (CNG) channel subunit tax-4 in larval chemotaxis t
104 d by adenylyl cyclase (AC)/cyclic nucleotide-gated (CNG) channels or by protein kinase A (PKA) activi
108 sual stimulation reveal an intrinsic voltage-gated conductance that profoundly alters the integrative
112 eptors are functional and exhibit robust ACh-gated currents blocked by alpha-bungarotoxin and strychn
113 whole-body surveys, quick reconstructions of gated data to select the optimal gate for a given attenu
116 ure of twisted bilayer graphene using a back-gated device architecture for angle-resolved photoemissi
117 is critical for the operation of electrolyte-gated devices in application-relevant environments.
120 it to operate an ultra-sensitive electrolyte-gated field-effect transistor (EGOFET) as a sensor and f
123 nanopore, which enables fast, selective, and gated flow of water de novo would remain challenging, su
126 unprecedented electrostatic control of dual-gated Gaussian heterojunction transistors for simplified
128 yperpolarization-activated cyclic nucleotide-gated (HCN) and small conductance calcium-activated pota
129 yperpolarization-activated cyclic nucleotide-gated (HCN) channels are essential for rhythmic activity
130 yperpolarization-activated cyclic nucleotide-gated (HCN) channels are major regulators of synaptic pl
137 equivalent, DDG-retro was preferred over RPM-gated in 13% of examinations, whereas the opposite occur
139 activate a shared pool of cardiac G protein-gated inwardly rectifying K(+) (GIRK) channels in SAN ce
144 discuss our current understanding of ligand-gated ion channel and G protein-coupled receptor complex
145 sitive neurons express the cyclic nucleotide-gated ion channel CNGA3, and that mouse, but not squirre
146 mitochondrial calcium uniporter is a Ca(2+)-gated ion channel complex that controls mitochondrial Ca
149 roton channel Hv1 is a member of the voltage-gated ion channel superfamily, which stands out in desig
150 otonin type 3 receptor (5-HT(3)) is a ligand-gated ion channel that converts the binding of the neuro
151 al homolog ELIC (Erwinia chrysanthemi ligand-gated ion channel) has a similar lipid sensitivity.
152 acetylcholine receptor, a pentameric ligand-gated ion channel, converts the free energy of binding o
153 otonin type 3A receptor, a pentameric ligand-gated ion channel, is crucial for regulating conductance
159 Targeting receptor proteins, such as ligand-gated ion channels and G protein-coupled receptors, has
162 1 is an outstanding representative of ligand-gated ion channels in ligand selectivity and sensitivity
163 T Changes in dendritic function, and voltage-gated ion channels in particular, are increasingly the f
164 Glutamate receptors are essential ligand-gated ion channels in the central nervous system that me
165 receptor-like (GLR) channels are amino acid-gated ion channels involved in physiological processes i
166 vary in their selectivity for human voltage-gated ion channels involved in the ventricular action po
168 nhibitory cell types, genes encoding voltage-gated ion channels responsible for depolarizing and repo
169 ium channels (VGCCs) and postsynaptic ligand-gated ion channels such as AMPA receptors (AMPARs) are o
170 Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic tran
172 D-aspartate receptors (NMDARs) are glutamate-gated ion channels that play critical roles in neuronal
173 5-HT(3) receptors are pentameric ligand-gated ion channels that regulate synaptic activity in th
175 ASICs have become bona fide neurotransmitter-gated ion channels, activated by the smallest neurotrans
176 at function as light-driven ion pumps, light-gated ion channels, and photosensors, with potential uti
177 onship among gating modifier toxins, voltage-gated ion channels, and the lipid membrane surrounding t
178 action potential depends on several voltage-gated ion channels, including Na(V), Ca(V), and K(V) cha
184 The EAG (ether-a-go-go) family of voltage-gated K(+) channels are important regulators of neuronal
186 hat induced autoimmunity against the voltage-gated KCNQ1 K(+) channels accelerates cardiac repolariza
190 2 (also known as KCNK5) channels generate pH-gated leak-type K(+) currents to control cellular electr
191 y on-target/off-tumor toxicity, we use logic-gated (log) GPC3-synNotch-inducible CD147-CAR to target
193 e IgA1 protease subscribes to an active-site-gated mechanism where a domain undergoes a 10.0 angstrom
194 Acid-sensing ion channels (ASICs) are proton-gated members of the epithelial sodium channel/degenerin
197 ced by the environmental pH, ruling out a pH-gated model and confirming that the chemistry of the His
199 istration of contrast media, and non-cardiac-gated multidetector CT with and without contrast media t
200 ing its application in high-performance back-gated n-type MoS(2) and p-type WSe(2) transistors with s
203 with reduced expression of SCN5a and voltage gated Na(+) (Na(V)1.5) channels as well as a shift in I(
204 is mediated by excessive activity of voltage-gated Na(+) and Ca(2+) channels that is initially counte
208 minated the onset response by moving voltage-gated Na+ channels (VGSCs) to closed-state inactivation
209 gating (real-time position management (RPM)-gated), no gating but using only the first 3 min of data
210 lanar lipid bilayers at acidic pH to form pH-gated nonselective cation channels that are opened upon
211 cohort and compared with BG using optimally gated (OG) and fully motion-corrected (elastic motion co
213 e investigate solution processed Electrolyte Gated Organic Field Effect Transistors (EGOFETs) based o
214 a label-free sensor based on an Electrolyte-Gated Organic Field-Effect Transistor (EGOFET) integrate
215 istor is changed from that of an electrolyte-gated organic field-effect transistor (EGOFET) to that o
216 p device integrating a multigate electrolyte gated organic field-effect transistor (EGOFET) with a 6.
217 y used for cell monitoring while Electrolyte-Gated Organic Field-Effect Transistors (EGOFETs) have ne
218 is tightly linked to the opening of voltage-gated P/Q-type Ca(2+) channels, the activation of which
219 xtracellular ATP, or inactivation of the ATP-gated P2X7R channel also compromised the effects of MerT
225 trically silent (KvS) members of the voltage-gated potassium (Kv) subfamilies Kv5, Kv6, Kv8, and Kv9
227 sistent with increased expression of voltage-gated potassium channel gene Kcna1 and decreased express
229 nsional structure of the human KCNQ1 voltage-gated potassium channel VSD in the intermediate state.
230 emonstrated that microglial Kv1.3, a voltage-gated potassium channel, was transcriptionally upregulat
231 idine (4AP) is a specific blocker of voltage-gated potassium channels (K(V)1 family) clinically appro
233 e VLS, we analyzed the expression of voltage-gated potassium channels in rodent and primate brains us
235 of action is via blockade of axonal voltage gated potassium channels, thereby enhancing conduction i
239 application of ALD increased outward voltage-gated potassium currents significantly, and simultaneous
240 embranes using the dynamic clamp and voltage-gated potassium ionic channels (Kv1.3) expressed in Xeno
241 ddition, we examined the role of the voltage-gated potassium Kv4.2 subunit, a molecular determinant o
242 d self-inhibitory because of ClC-5's voltage-gated properties, but shunt conductance facilitated furt
243 Here, we report a light- and cellular stress-gated protein switch based on cofilin-actin rod formatio
253 s, in the presence of a primer, P(1), to the gated replication of the scaffolds and to the displaceme
255 nce, Na-activated K channels (Slo2), voltage-gated (SCN) Na(+) and Na(+) leak channels, nonselective
260 osa) use tetrodotoxin (TTX) to block voltage-gated sodium (Na(v)) channels as a chemical defense agai
262 ntracellular proteins which regulate voltage-gated sodium (Na(v)) channels in the brain and other tis
263 n mice by inhibiting inactivation of voltage-gated sodium (Na(V)) channels involved in nociceptive si
264 BFOX2(40)-driven splicing defects in voltage-gated sodium and potassium channels, which alter their e
267 und alterations in the properties of voltage-gated sodium channel currents in Jedi-1 null neurons.
273 estigated the effect of LITAF on the voltage-gated sodium channel Nav1.5, which is critical for cardi
275 ffinity and in vitro activity at the voltage-gated sodium channel subtype 1.7 (Na(V)1.7), a channel t
276 teractions between CBD and the NavMs voltage-gated sodium channel, and electrophysiology to show the
277 in (TTX), a neurotoxin that binds to voltage-gated sodium channels (Na(v) proteins), arresting electr
284 e in the density of Nav1.5-generated voltage-gated sodium current I (Na) and Nav1.5 surface protein l
286 how that our model reproduces neuromodulator-gated spike-timing-dependent plasticity as observed in t
288 also demonstrate light- and cellular stress-gated switch function in cultured hippocampal neurons.
291 photoluminescence (PL) lifetime enables time-gated (TG) detection without autofluorescence background
298 rin-like compounds that open the two voltage-gated type 1 potassium (K(V)1) channels K(V)1.5 and Shak
299 regions of interest.Objectives: Respiratory-gated, ultrashort echo time magnetic resonance imaging w