ライフサイエンスコーパス: gateway

1 through a southern opening of the Tasmanian Gateway.

2 o the ligand pocket, or in a putative ligand gateway.

3 ls the presence of an alternative regulatory gateway.

4 ex might be described as the guardian of the gateway", a reciprocal relationship we now show to be mo

5 This open channel then serves as both a gateway and a template for flagellar rod assembly.

6 In addition, the utility of the gateway and alternative sequences in predicting substanc

7 ependent in vitro DNA recombinant reactions, Gateway and Cre-loxP.

8 ion is required to access the CIPRES Science Gateway and NSF XSEDE's large computational resources.

9 al that dsDNA binding and bending, the ssDNA gateway, and double-base unpairing flanking the scissile

10 The Molecule Pages and the Signaling Gateway are routinely accessed by a very large research

11 Routes to other information gateways are included, for example to relevant pages fro

12 The main Pacific gateways are, according to Alvarez, the southeast Indian

13 Eocene cooling, the opening of the Tasmanian Gateway better explains Southern Ocean surface water and

14 wo schemes had coupled open states, only one gateway between the closed and open aggregates, and at l

15 The nuclear pore complex (NPC) is the sole gateway between the nucleus and the cytoplasm.

16 tic social signals by acting as a regulatory gateway between the stimulus analysis of the brainstem a

17 It resulted from the closure of marine gateways between the Atlantic Ocean and the Mediterranea

18 complexes (NPCs) act as effective and robust gateways between the nucleus and the cytoplasm, selectin

19 The Inka cell therefore functions as a "gateway cell", whose secretion of ETH serves as a key do

20 y characterize the proteome, we attempted to Gateway-clone all predicted protein-encoding open readin

21 highly representative worm cDNA library and Gateway-clone approximately 4200 ORFs missed earlier and

22 s of approximately 8,100 currently available Gateway-cloned open reading frames and detected approxim

23 Based on Gateway cloning methodology, we have engineered a destin

24 eamlined and PCR-independent Golden Gate and Gateway cloning strategies, which will facilitate transc

25 igh-throughput platform that complements the Gateway cloning system for gene cloning and functional g

26 elegans ORFeome resource, generated with the Gateway cloning system, can be used as a starting point

27 e recombinase and the commercially available Gateway cloning system.

28 ghput approaches, makes use of both TOPO and Gateway cloning technologies for directional, efficient

29 Gateway cloning technology facilitates high-throughput c

30 recombination-based cloning systems, such as Gateway cloning technology, are extremely useful for eff

31 legans genes were cloned using the MultiSite Gateway cloning technology.

32 oned into a DNA immunization vector with the Gateway cloning technology.

33 recombinant protein expression, applying the Gateway cloning/expression technology and utilizing a st

34 We describe here a set of Gateway-compatable vectors with fluorescent tags incorpo

35 onally, system components are constructed in Gateway compatible vectors for the rapid cloning of doxy

36 Specifically, we used Gateway-compatible C. elegans ORFeome clones as starting

37 Here, we introduce a MultiSite Gateway-compatible inducible system for Arabidopsis (Ara

38 Here, using a Gateway-compatible MS2 labeling system, we generated sta

39 ort on the construction of a novel series of Gateway-compatible plant transformation vectors containi

40 ibe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressi

41 This Gateway-compatible system enables high-throughput screen

42 eering) to capture a genomic fragment into a Gateway-compatible vector.

43 nally, we introduce a set of traditional and Gateway-compatible vectors to facilitate construction of

44 Taken together, the Gateway-compatible Y1H system will allow the high-throug

45 Gateway-compatible yeast one-hybrid (Y1H) assays present

46 Gateway-compatible yeast one-hybrid (Y1H) assays provide

47 We developed a Gateway-compatible yeast one-hybrid (Y1H) system that en

48 otal synthesis of berkeleyone A, a potential gateway compound to a plethora of fungal-derived meroter

49 ified the need for continued research on the gateway concept and on other behavioral health outcomes

50 gh-throughput generation of mutant clones by Gateway, confirmation of variant identity by barcoding a

51 It has also been proposed as a gateway connecting hydrothermal vents in different ocean

52 These results reveal an unknown gateway connecting SVZ neurogenesis to neuronal activity

53 rhinal cortex (EC) plays a crucial role as a gateway connecting the neocortex and the hippocampal for

54 course of the lifespan and through critical gateway contexts, including homes, schools, and workplac

55 We review the various types of Gateway destination vectors that are currently available

56 oters can be transferred easily into various Gateway Destination vectors to drive expression of marke

57 y prevalent and impairing and are considered gateway disorders in that they predict adult psychiatric

58 ine hydrochloride used intranasally may be a gateway drug or behavior to using crack cocaine.

59 do not support the notion that alcohol is a gateway drug to cocaine.

60 ibute, we extended our series of studies on 'gateway drug' effects in animal models of drug abuse.

61 abled by the tectonic opening of key oceanic gateways during the break-up of Gondwana (for example, b

62 12,500 C. elegans ORFs are now available as Gateway Entry clones for various reverse proteomics (ORF

63 80 TagModules is that they are cloned into a Gateway entry vector, thus facilitating rapid transfer t

64 video gaming and its potential to serve as a gateway experience that might motivate players to increa

65 Bax and Bak comprise the mitochondrial gateway for apoptosis induced by diverse stimuli.

66 otor neurons and that is thought to act as a gateway for auditory information into the song system, s

67 lear pore complex (NPC) constitutes the sole gateway for bidirectional nucleocytoplasmic transport.

68 f CPG2/F-actin association by PKA provides a gateway for cellular control of synaptic receptor intern

69 which indicates that such states act as the gateway for charge separation.

70 This transition would represent a gateway for differentiation and reprogramming of somatic

71 Contrary to the view that PFN acts as a gateway for granzymes through the plasma membrane, monom

72 us, the arcuate nucleus (ARC) functions as a gateway for hormonal signals of energy balance, such as

73 on lined by E202, E203, and A404 as the main gateway for hydration.

74 worldwide evolution of M. tuberculosis and a gateway for investigating genotype-disease phenotype rel

75 The coronary sinus is the gateway for left ventricular (LV) epicardial lead placem

76 r the capture of blood-borne pathogens and a gateway for lymphocytes entering the white pulp.

77 ite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.

78 nucleus of the solitary tract (NTS) is a key gateway for meal-related signals entering the brain from

79 nuclear pore complex (NPC) is the principal gateway for molecular exchange between nucleus and cytop

80 ntestine, were previously shown to provide a gateway for murine NoV (MNV) into the host, but the rela

81 The nuclear pore complex (NPC), the sole gateway for nucleocytoplasmic exchange in eukaryotic cel

82 piriform cortical pyramidal cells and is the gateway for olfactory input to the hippocampus.

83 t to the active center, which may serve as a gateway for polymerization of substrates.

84 Collectively, our results provide a gateway for probing the diverse functions of PARP in a s

85 tion with DnaB, they may act as a functional gateway for regulation of primer synthesis by tau-intera

86 using what we called a peri-rectal oncologic gateway for retroperitoneal endoscopic single site surge

87 Gene Prospector provides an online gateway for searching for evidence about human genes in

88 both the ER and mitochondria as an essential gateway for selected apoptotic signals.

89 The nuclear pore complex is the gateway for selective traffic between the nucleus and cy

90 Arsine generation is the gateway for several sensitive and selective methods of A

91 As a gateway for solutes, the endodermis may also serve as an

92 Finally, a gateway for ssDNA translocation and an alternative stran

93 nd second helices is disordered, providing a gateway for substrate entry and product exit.

94 r uptake pathway is now being evaluated as a gateway for the delivery of therapeutic and diagnostic a

95 he transmodal node that acts as the critical gateway for the dominant transformation.

96 The identification of rafts as the gateway for the entry and exit of filoviruses and raft-d

97 The dentate gyrus is a key input gateway for the hippocampus, and dentate function is pot

98 dicate that hRad54 protein serves as a dsDNA gateway for the hRad51-ssDNA filament, promoting binding

99 Nuclear pore complexes (NPCs) provide a gateway for the selective transport of macromolecules ac

100 tip complex and the host cell, serving as a gateway for translocation of effector proteins by creati

101 ulatory plasticity in bacteria and provide a gateway for understanding bacterial phenotypic variation

102 Although the hippocampus has provided the gateway for understanding stress effects on the brain, l

103 mes, favoring the population of CT states as gateways for direct charge generation.

104 nt biosynthetic and degradative pathways and gateways for genomic manipulation.

105 he plasma membrane and have been shown to be gateways for HIV-1 budding as well as entry into T cells

106 Nuclear pore complexes (NPCs) form gateways for material transfer across the nuclear envelo

107 associated databases have great potential as gateways for navigating, accessing, and visualizing a wi

108 Nuclear pore complexes (NPCs) are gateways for nucleocytoplasmic exchange.

109 y gene editing have opened up many potential gateways for the autologous treatment of hereditary live

110 phobic cavities in channel proteins serve as gateways for transfer of ions across membranes, but thei

111 e posterior parietal cortex provide critical gateways for transforming perception into recognition, w

112 extrastriate visual cortex and that they are gateways for ventral and dorsal streams.

113 s (PIP) subfamily represents one of the main gateways for water exchange at the plasma membrane (PM).

114 e lambda(3)-iodane intermediate is also the "gateway" for reactions that are observed only for strain

115 RE, represent important output stations (or gateways) for the actions of mPFC on diverse subcortical

116 Above the active site, a helical cap over a gateway formed by two helices enforces ssDNA threading a

117 ic to the few lowland regions that provide a gateway from north to south between the Caspian and Blac

118 Licensing serves as a gateway from the embryonic processes shared between the

119 3 of the medial entorhinal cortex is a major gateway from the neocortex to the hippocampus.

120 ing in the amygdala may serve as a molecular gateway from use to abuse.

121 ard DNA assembly methods including ligation, Gateway, Gibson, and Golden Gate.

122 pollution particulate material on olfactory gateways has not been reported.

123 The gateway hypothesis posits that initial exposure to legal

124 We tested the gateway hypothesis using established rat alcohol exposur

125 ding to lowered FFA and reduced EGP ("Single Gateway Hypothesis").

126 ransport of insulin, we proposed the "single gateway hypothesis," which supposes an indirect regulati

127 particular risk factors, as specified by the gateway hypothesis.

128 ed our physiological findings and the single gateway hypothesis.

129 at Drake Passage opened before the Tasmanian Gateway, implying the late Eocene establishment of a com

130 conformational change is the opening of the gateway in a pocket where the location of the leaving gr

131 complex may provide a potential therapeutic gateway in human liver and colon cancer.

132 sula might be an emergent pathophysiological gateway in schizophrenia.

133 otypes, pointing to Egypt as the more likely gateway in the exodus to the rest of the world.

134 carry water into the mantle and are a major gateway in the global geochemical water cycle.

135 olecular triplet states constitute a crucial gateway in the photochemical reactions of organic molecu

136 have traditionally been proposed as feasible gateways in light of geographic, paleoclimatic, archaeol

137 r potential (TRP) ion channels are molecular gateways in sensory systems, an interface between the en

138 Then, we demonstrate how these gateway institutions, which could provide access to upwa

139 he PubChem Power User Gateway (PUG)-a common gateway interface (CGI) that exchanges data through eXte

140 enzymes can function in combination opens a gateway into a rich family of natural products.The biosy

141 Heritable disorders offer a gateway into biological underpinnings, as illustrated by

142 The hippocampus provided the gateway into much of what we have learned about stress a

143 erapeutic intervention in CMV disease, and a gateway into studying a largely uncharted viral process

144 lamo-cortical pathway is the crucial sensory gateway into the cerebral cortex.

145 ogens interact with and exploit M cells as a gateway into the host.

146 tion of the northern margin of the Tasmanian Gateway into the mid-latitude westerly wind band, which

147 In searching for T-cell gateways into and out of the meninges, we discovered fun

148 hat Clovis had its origins well south of the gateways into the continent, and (ii) expand the make-up

149 ed saliency coding from neurons in two early gateways into the visual system: the primary visual cort

150 The attB1 site in the Gateway (Invitrogen) bacterial expression vector pDEST17

151 binding protein (GBP), in which the putative gateway is a Gln side chain.

152 pect to the diene, referred to as the "axial gateway", maintains the electrophilicity of the catalyst

153 of mutant P68A and found that, although the gateway may be important for photocycle initiation, its

154 The Signaling Gateway Molecule Pages (SGMP) database provides highly s

155 The UCSD-Nature Signaling Gateway Molecule Pages provides essential information on

156 es to the tectonic opening of Southern Ocean gateways, more recent investigations invoked a dominant

157 Tonsils are strategically located in the gateway of both alimentary and respiratory tracts repres

158 These results establish the eye as a major gateway of respiratory infection and a respiratory virus

159 corticostriatal glutamatergic synapses, the gateway of the BG, is correlated to the onset of PD-rela

160 vince on China's southwestern border was the gateway of the country's AIDS epidemic.

161 l strongly uplifting regions acting as major gateways of perturbations spreading in the atmosphere.

162 nt-ocean boundaries, that the deep Tasmanian Gateway opened 33.5 +/- 1.5 million years ago (the error

163 idening of the South Atlantic, together with gateway opening at Drake Passage would lead, by mid-Mioc

164 solation of Antarctica due to southern ocean gateway opening, and declining atmospheric CO2.

165 ve been interpreted as a unique signature of gateway opening, but at present both mechanisms remain p

166 rt available evidence that CO2 drawdown--not gateway opening--caused Antarctic ice sheet growth, and

167 Conversely, gateway openings had much less impact on ocean thermal s

168 An arginine gateway opens, allowing solvent exposure and protonation

169 SGMP is available at www.signaling-gateway.org/molecule.

170 cally steer an inverted ss 5'-flap through a gateway over FEN1's active site and shift dsDNA for cata

171 s highlights include newly designed home and gateway pages; a new 'multi-region' track display config

172 Among youths who did exhibit the gateway pattern, only delinquency was more strongly rela

173 A; direct the target region into the helical gateway, permitting only nonbase-paired oligonucleotides

174 resources to create the Pathogen Interaction Gateway (PIG).

175 our simulation the opening of Southern Ocean gateways plays a secondary role in this transition, rela

176 onfirm that isoelectric substitutions at the gateway position have little effect on Ca2+ affinity, th

177 ty, suggesting that a negative charge at the gateway position increases the equilibrium stability of

178 signaling sites, providing evidence that the gateway position is an important physiological determina

179 Neutral side chains at the gateway position yielded a 590-fold range of Tb3+ dissoc

180 The apoptosis gateway protein Bax normally exists in the cytosol as a

181 We found that the LINGO1 protein acts as a gateway protein internalizing into the tumor cells when

182 activation of pro-apoptotic BAX and BAK, the gateway proteins to the mitochondrial pathway of apoptos

183 s residue suggests that it could serve as a "gateway", providing steric and electrostatic control ove

184 The PubChem web site and Power User Gateway (PUG) web service allow users to interact with t

185 ities or E-Utils) and the PubChem Power User Gateway (PUG)-a common gateway interface (CGI) that exch

186 sequences without termination codons and are Gateway(R) compatible.

187 andidate against dengue fever and presents a Gateway((R)) plastid transformation vector for inducible

188 l ABC and putative auxin transport genes and Gateway((R))-compatible expression vectors for functiona

189 Bile salt hydrolases (BSHs) catalyze the "gateway" reaction in a wider pathway of bile acid modifi

190 se results suggest a role for PPARdelta as a gateway receptor whose relative levels of expression can

191 ibrary using ORF-specific primers, cloned by Gateway recombination cloning and then sequenced to gene

192 vectors has been adapted for high throughput Gateway recombination cloning.

193 nto C. elegans, demonstrating that the short Gateway recombination site between the promoter and the

194 nstructed a modified TRV vector based on the GATEWAY recombination system, allowing restriction- and

195 chromosome (BAC) and the Invitrogen in vitro Gateway recombination system, creating DBAC-GW.

196 Finally, through a simple in vitro Gateway recombination, the modified genomic fragment is

197 of the human ORFeome using a newly improved Gateway recombinational cloning approach.

198 Generated by Gateway recombinational cloning, this collection contain

199 The dentate gyrus is a primary gateway regulating cortical input to the hippocampus and

200 of North Atlantic Deep Water to reconstruct gateway-related changes in the AMOC mode.

201 The gateway residues Tyr34, His30 and a tightly bound water

202 , it has been proposed that Y98 and P68 are "gateway residues" between which the chromophore must pas

203 nd flowing current flow across the Tasmanian Gateway resulted in cooling of Antarctic surface waters

204 abuse potential, tolerance, withdrawal, and gateway risks of medical use of cannabinoid drugs.

205 They also evaluated the accuracy of the "gateway sequence" (illicit drug use following licit drug

206 rugs and then transitioned to marijuana use (gateway sequence) (N=97), and boys who used marijuana be

207 pants who used marijuana did not exhibit the gateway sequence, thereby demonstrating that this patter

208 for predicting substance use disorder as the gateway sequence.

209 observations about the "stepping-stone" or "gateway" sequences that link the use of alcohol, tobacco

210 Thus, kinetic tuning by the gateway side chain exhibits both transition state and gr

211 he present study has engineered the putative gateway side chain of a model EF-hand site and determine

212 , thereby supporting the hypothesis that the gateway side chain provides kinetic tuning of Ca2+ signa

213 Acidic gateway side chains (Glu, Asp) are found to reduce Ca2+

214 In natural EF-hand sequences, different gateway side chains are used by slow buffering sites and

215 g that the enzymatically controlled vascular gateway specifically opens by cleavage of NPY by CD26 si

216 ic proof for the existence of an electronic "gateway" state localized on the Au-C bond that is respon

217 chemoreceptor trimers, suggests a series of "gateway" states for chemoreceptor lattice assembly, and

218 A gateway strategy designed to provide general synthetic a

219 r tags and re-encountered using an automated gateway system fitted at the entrance to the colony.

220 The versatility inherent to the Gateway system suggests that additional HT-RNAi librarie

221 a high-throughput cloning approach using the Gateway system to create a large set of expression clone

222 The recombinational cloning involved in the Gateway system, which permits the highly efficient and p

223 s, we utilized the newly developed MultiSite Gateway system.

224 Gateway technology has been embraced by a number of plan

225 Nuclear pore complexes (NPCs) are the sole gateways that facilitate this macromolecular exchange ac

226 tinental margins to close the Miocene marine gateways, thereby causing the Messinian salinity crisis.

227 bited by the Greenland-Scotland ridge, but a gateway through the Faeroe-Shetland basin has been hypot

228 The lateral geniculate nucleus (LGN) is the gateway through which retinal information reaches the ce

229 n ACCd suggests that this area constitutes a gateway through which the choice system informs motor sy

230 Thus, NPD provides a gateway through which the nuclear proteome may be explor

231 We provide the gateway to a number of MLST schemes, each of which conta

232 and the genetic control of implantation, the gateway to a successful pregnancy.

233 Aqueous surfaces act as a gateway to absorption and aqueous-phase reaction of gase

234 ss and - in combination with language - is a gateway to abstract and unobservable information.

235 he function of neural circuits and it is the gateway to behavioral output.

236 The mitochondrial gateway to cell death is a frequent target for tumor sup

237 Instead, a gateway to chlorophyll Q(y) excitations is furnished thr

238 Auditory perception is our main gateway to communication with others via speech and musi

239 ammonia lyases (PALs), either alone or as a gateway to deracemization cascades (giving (S)- or (R)-a

240 nanophotonic light trapping open up the new gateway to enhance the absorption of solar energy beyond

241 with the hypothesis that A1 may also form a gateway to higher, more specialized cortical areas.

242 Appreciative Inquiry is being perceived as a gateway to knowledge translation rather than transformat

243 emory suppression and the neurons that are a gateway to long-term memory formation.

244 the hypothetical first stage is not merely a gateway to long-term memory, but also temporary storage

245 The EBI SRS server is a primary gateway to major databases in the field of molecular bio

246 Immune escape is a critical gateway to malignancy.

247 tein of the BCL-2 family that represents the gateway to mitochondrial apoptosis.

248 xic stress has been shown to be an essential gateway to mitochondrial dysfunction and activation of t

249 proteins BAX and BAK constitute an essential gateway to mitochondrial dysfunction and programmed cell

250 mber, BAX or BAK, appears to be an essential gateway to mitochondrial dysfunction required for cell d

251 n Bcl-2 family proteins, provide a requisite gateway to mitochondrial injury.

252 al model of the immune response to provide a gateway to more spatial and mechanistic investigations o

253 ng the future role of IFN-gamma Elispot as a gateway to moving forward with clinical trials of candid

254 Our study therefore opens up a gateway to new assembled inorganic suprastructures with

255 y-associated genes provides an extraordinary gateway to new insights into higher cortical function.

256 ion to its direct harm, tobacco use may be a gateway to other substance abuse and a marker of other h

257 oxypregnane natural products, representing a gateway to over 100 family members.

258 The reported method opens a gateway to periodically patterning polymers and differen

259 consider the provision of PEP as a potential gateway to PrEP.

260 external carotid artery, which serves as the gateway to select targets, including the salivary glands

261 propagated northwards, opening an equatorial gateway to shallow and intermediate circulation.

262 ansistor envisioned by Datta and Das opens a gateway to spin information processing.

263 Host plant penetration is the gateway to survival for holoparasitic Cuscuta and requir

264 consists of the caudate and putamen, is the gateway to the basal ganglia.

265 thalamus, a highly evolved sensory and motor gateway to the cortex, has been implicated in the pathop

266 , and suggested that "if the thalamus is the gateway to the cortex, the reticular complex might be de

267 of creating a resource that can be used as a gateway to the field.

268 Assembly of the nuclear pore, gateway to the genome, from its component subunits is a

269 Area Spt acts as a gateway to the hallucination-generating cerebral network

270 The entorhinal cortex functions as the gateway to the hippocampal formation.

271 he entorhinal cortex (EC) is regarded as the gateway to the hippocampus and thus is essential for lea

272 The dentate gyrus serves as a gateway to the hippocampus, filtering and processing sen

273 he entorhinal cortex (EC) is regarded as the gateway to the hippocampus; the superficial layers (laye

274 irhinal cortex (PR) is a major informational gateway to the LA and nearby structures.

275 ed at becoming a one-stop guided information gateway to the major bioinformatics databases and softwa

276 roteins that together represent an essential gateway to the mitochondrial apoptotic pathway, would pr

277 the eukaryotic cell and forms the exclusive gateway to the nucleus.

278 e last decade, notably by providing a direct gateway to the processes involved in atherogenesis and i

279 ructure and function in yeast, it provides a gateway to the systematic expansion of the genetic codes

280 st that the LGN, traditionally viewed as the gateway to the visual cortex, may be an early gatekeeper

281 The GDAP web application is a gateway to this information and can be used to understan

282 converge at the core promoter, which is the gateway to transcription.

283 The hippocampus has also been a gateway to understanding lasting epigenetic effects of e

284 The LGN, traditionally viewed as the gateway to visual cortex, may also serve as a 'gatekeepe

285 that the ninth EF-loop position serves as a "gateway" to modulate the kinetics of Tb3+ binding and re

286 This gateway, together with subsiding volcano-tectonic barrie

287 trates involvement of the strictly conserved gateway tyrosine (Y34) in exogenous ligand interactions.

288 reading frames (ORFs) encoded in a versatile Gateway vector system.

289 All ESTs are in the Gateway vector to facilitate functional assessment of th

290 sgenic rice and created a set of DsRed-based gateway vectors for combining with the marker lines.

291 e few parts of the Pacific rim (here termed 'gateways') where there are no continental roots or subdu

292 ntral striatum (VS) is thought to serve as a gateway whereby associative information from the amygdal

293 for example, by the opening of the Tasmanian Gateway, which connects the Indian and Pacific oceans).

294 ter legacy of prestin, and this intermediary gateway, which shuttles anion-bound molecules into the v

295 ate is complicated by differences in oceanic gateways, which affect where deep waters form and how th

296 from the tectonic opening of Southern Ocean gateways, which enabled the formation of the Antarctic C

297 Our results identify the endodermis as a gateway with an ABA-dependent guard, which prevents root

298 rated these parallel applications in science gateways with a web-based portal.