ライフサイエンスコーパス: geminivirus

1 is the first report of an aphid-transmitted geminivirus.

2 ES activity of the capsid protein of a plant geminivirus.

3 wo heterologous species of cassava-infecting geminiviruses.

4 ployment of transgenic strategies to control geminiviruses.

5 transposon, not found in the GRD5 family or geminiviruses.

6 ding common region sequences of heterologous geminiviruses.

7 oligomers with the Rep proteins of the other geminiviruses.

8 determinants of genome size in the bipartite geminiviruses.

9 cipate in defense against the DNA-containing geminiviruses.

10 (WDV), which are important cereal-infecting geminiviruses.

11 nts uniquely show enhanced susceptibility to geminiviruses.

12 tion (RdDM) as an epigenetic defense against geminiviruses.

13 tial role for TIFY4B in host defense against geminiviruses.

14 develop crops that are resistant to diverse geminiviruses.

15 istone H3 and the capsid proteins of various geminiviruses.

16 f the rate of nucleotide substitution in the geminiviruses.

17 ences gene silencing for single-stranded DNA geminiviruses.

18 g in the GRD3 family, involved a free-living geminivirus, a Helitron and perhaps also GRD5.

19 nsferred to plants to make them resistant to geminiviruses, a damaging family of DNA viruses.

20 chanisms besides gene silencing also control geminivirus accumulation at high temperatures.

21 When challenged with geminiviruses, accumulation of viral DNA was reduced by

22 ults, in addition to the large host range of geminiviruses, advocate the use of replicons for plant g

23 replication-associated protein (AC1) of the geminivirus African cassava mosaic virus (ACMV) from Cam

24 Three sequence motifs conserved among geminivirus AL1 proteins and initiator proteins from oth

25 Geminivirus AL2 and L2 proteins cause enhanced susceptib

26 By examining geminivirus AL2 and L2 suppressor activities, we show th

27 Geminivirus AL2/C2 proteins play key roles in establishi

28 towards recurrent dynamic interplay between geminivirus and plant DNA in evolution.

29 of recombination between distinct bipartite geminiviruses and establish that the bipartite genome ca

30 Evidence is emerging that geminiviruses and plant pararetroviruses can interact wi

31 These results showed that geminiviruses and RNA viruses interface with the host pa

32 olling infection of single-stranded (ss) DNA geminiviruses and ssRNA viroids, respectively, but both

33 as distantly related to the plant-infecting geminiviruses and the fungi-infecting Sclerotinia sclero

34 Plant DNA viruses-- both the ssDNA geminiviruses and the reverse-transcribing pararetroviru

35 ngle-stranded DNA animal circoviruses, plant geminiviruses, and nanoviruses may have evolved from pro

36 They also indicate that geminiviruses are able to modify host metabolism to thei

37 Geminiviruses are devastating viruses of plants that pos

38 Geminiviruses are DNA viruses that cause severe crop los

39 Geminiviruses are DNA viruses that replicate and transcr

40 The DNA-containing geminiviruses are no exception, and the AL2 protein (als

41 r pathway may be considered essential, since geminiviruses are particularly prone to recombination.

42 Geminiviruses are plant viruses with circular single-str

43 Geminiviruses are plant-infecting viruses with small cir

44 Geminiviruses are single-stranded DNA viruses that cause

45 Geminiviruses are small DNA viruses that replicate in th

46 Geminiviruses are small DNA viruses that use plant repli

47 Geminiviruses are ssDNA viruses that infect a range of e

48 Like most plant viruses, geminiviruses are targeted by RNA silencing and encode s

49 This work highlights the utility of geminiviruses as models for de novo RdDM and places DRB3

50 Here, we use geminivirus-based replicons for transient expression of

51 Moreover, integration of geminivirus-based vectors enables precise gene editing t

52 ctors interacting with the NSP and MP of the geminivirus Bean dwarf mosaic virus (BDMV).

53 hesis, the DNA-A and DNA-B components of the geminiviruses bean dwarf mosaic virus (BDMV) and tomato

54 gulating the nuclear export of the bipartite geminivirus (Begomovirus) DNA genome was recently sugges

55 All characterized whitefly-transmitted geminiviruses (begomoviruses) with origins in the New Wo

56 Emergence of B. tabaci-transmitted geminiviruses (begomoviruses), ipomoviruses, and torrado

57 Consequently, nonrecovery-type geminiviruses behaved like recovery-type viruses under h

58 lts indicate that Ty-1 confers resistance to geminiviruses by increasing cytosine methylation of vira

59 ene silencing (VIGS) vector derived from the geminivirus Cabbage leaf curl virus (CaLCuV) to assess n

60 ve developed a system based on the bipartite geminivirus cabbage leaf curl virus (CbLCV) that allows

61 Similar results were seen with another geminivirus, cabbage leaf curl virus (CaLCuV), carrying

62 In addition, our results establish that geminiviruses can be useful models for genome methylatio

63 to yellow leaf curl China virus (TYLCCNV), a geminivirus, can phenocopy to a large extent disease sym

64 Dicot-infecting geminiviruses carry genes that encode multifunctional AL

65 Geminiviruses constitute a large family of single-strand

66 (Gossypium hirsutum) was developed from the geminivirus Cotton leaf crumple virus (CLCrV).

67 tion as a defense against DNA viruses, which geminiviruses counter by inhibiting global methylation.

68 To understand how geminiviruses defeat host mechanisms that limit infectiv

69 Our results demonstrate that geminivirus-derived vectors can be used to study genes i

70 gulating the nuclear export of the bipartite geminivirus DNA genome was recently suggested by the fin

71 Geminiviruses encapsidate single-stranded DNA genomes th

72 All geminiviruses encode a conserved protein (Rep) that cata

73 Most dicot-infecting geminiviruses encode a replication enhancer protein (C3,

74 rt that expression in transgenic plants of a geminivirus-encoded AC4 protein from African cassava mos

75 The combined properties of the geminivirus-encoded movement protein and plasmodesmata w

76 irus as suppressors of PTGS, indicating that geminiviruses evolved differently in regard to interacti

77 Like all members of the geminivirus family, CMBs have small, circular single-str

78 golden mosaic virus (TGMV), a member of the geminivirus family, encodes one essential replication pr

79 golden mosaic virus (TGMV), a member of the geminivirus family, has a single-stranded DNA genome tha

80 Tomato golden mosaic virus, a member of the geminivirus family, has a single-stranded DNA genome tha

81 golden mosaic virus (TGMV), a member of the geminivirus family, is essential for viral replication i

82 amino acid sequence conservation across all geminivirus genera.

83 ate in a nuclear siRNA pathway that leads to geminivirus genome methylation.

84 n rates contribute to the rapid evolution of geminivirus genomes in plants.

85 The DNA genomes of geminiviruses have a limited coding capacity that is com

86 lant kinases contributes to the evolution of geminivirus-host interactions.

87 -4 did not confer resistance to the reporter geminivirus; however, it did activate a resistance-relat

88 on chromosome 1, which is designated gip-1 (geminivirus immunity Pla-1-1).

89 ome-mediated gene silencing from a bipartite geminivirus in Nicotiana benthamiana.

90 nome for isolates of five species of cassava geminiviruses in cassava (Manihot esculenta, Crantz) and

91 yed by these AC2 and AC4 proteins of cassava geminiviruses in regulating anti-PTGS activity and their

92 Some geminiviruses in the genus Begomovirus exhibit phloem li

93 Here, we report the effect of temperature on geminivirus-induced gene silencing by quantifying virus-

94 ure can have a major impact on the extent of geminivirus-induced gene silencing.

95 Cassava geminivirus-induced RNA silencing increased by raising t

96 ic requirements of rapidly growing cells and geminivirus-infected cells that have been induced to ree

97 roteins only accumulate in young tissues and geminivirus-infected mature leaves, the GRIK-SnRK1 casca

98 plants expressing the viral proteins and in geminivirus-infected plant tissues.

99 nctions of these host factors in healthy and geminivirus-infected plants are discussed.

100 processes during early plant development and geminivirus infection by activating SNF1-related kinases

101 Together, these results demonstrate that geminivirus infection induces the accumulation of a host

102 e importance of AL1-pRBR interactions during geminivirus infection of plants.

103 B in N. benthamiana increases in response to geminivirus infection, which would result in suppression

104 n are regulated during plant development and geminivirus infection.

105 eficient host plants are hypersusceptible to geminivirus infection.

106 way components, or ADK are hypersensitive to geminivirus infection.

107 ggest that the high evolutionary rate of the geminiviruses is not primarily due to frequent recombina

108 cular single-stranded DNA of phytopathogenic geminiviruses is propagated by three modes: complementar

109 tion of plants with diverse RNA viruses or a geminivirus lacking a functional L2 gene.

110 Geminiviruses may counter this defense response through

111 -circle initiators and support the idea that geminiviruses may have evolved from plasmids associated

112 Moreover, certain plant monopartite geminiviruses may operate similarly to mammalian DNA vir

113 en response via a common mechanism, and that geminiviruses modulate plant cell cycle status by differ

114 The geminivirus movement protein NSP is essential for virus

115 the flow of genetic material among different geminiviruses occurring in the same geographical region.

116 AL2 and L2 are related proteins encoded by geminiviruses of the Begomovirus and Curtovirus genera,

117 SEGS-1 has no homology to geminiviruses or their associated satellites, but the ca

118 Most whitefly-transmitted geminiviruses possess bipartite DNA genomes, and this fe

119 The bipartite geminiviruses possess two movement proteins, BV1 and BC1

120 The single-stranded DNA geminiviruses produce transcripts from both strands (vir

121 The geminivirus protein AL1 initiates viral DNA replication,

122 Here we present evidence that the related geminivirus proteins AL2 and L2 are able to suppress thi

123 that the inactivation of ADK and SNF1 by the geminivirus proteins represents a dual strategy to count

124 llow us to propose that as a countermeasure, geminivirus proteins reverse TGS by nonspecifically inhi

125 support RNA silencing, and indicate that the geminivirus proteins suppress silencing by a novel mecha

126 irected silencing in a manner similar to the geminivirus proteins.

127 e genetic diversity reflected in present-day geminiviruses provides important insights into the evolu

128 ly, we discovered multiple direct repeats of geminivirus-related DNA (GRD) sequences clustered at a s

129 Nicotiana, gave rise to multiple repeats of geminivirus-related DNA, GRD, in the genome.

130 and GRIK2, which were first characterized as geminivirus Rep interacting kinases, are phylogeneticall

131 fs-motifs I, II, and III-in the N termini of geminivirus Rep proteins are essential for function.

132 ng sequence and structural homology to other geminivirus Rep proteins.

133 dentified a fourth sequence, designated GRS (geminivirus Rep sequence), in the Rep N terminus that di

134 Geminivirus Rep-Interacting Kinase (GRIK)1 and GRIK2 pho

135 Geminivirus Rep-interacting kinase 1 (GRIK1) and GRIK2 c

136 AL2/C2 proteins interact strongly with host geminivirus Rep-interacting kinases (GRIKs), which are u

137 Geminiviruses replicate in nuclei of mature plant cells

138 Geminiviruses replicate single-stranded DNA genomes thro

139 nce of these results for AL1 function during geminivirus replication and transcription is discussed.

140 The geminivirus replication factor AL1 interacts with the pl

141 in interactions is discussed with respect to geminivirus replication in plant cells.

142 proteins had no effect on the efficiency of geminivirus replication in transient-replication assays,

143 air template and pleiotropic activity of the geminivirus replication initiator proteins.

144 The geminivirus replication protein (Rep) is a good target f

145 The geminivirus replication protein AL1 interacts with retin

146 at a truncated version of GRIK1 binds to the geminivirus replication protein AL1.

147 o acid sequence is strongly conserved across geminivirus replication proteins, plays a role in pRBR b

148 planta system for functional analysis of the geminivirus replication-associated protein (Rep) in tran

149 ycle, providing an environment conducive for geminivirus replication.

150 of C3-C3, C3-C1, and C3-PCNA interactions in geminivirus replication.

151 Here, we use geminivirus replicons to create heritable modifications

152 We demonstrate the feasibility of using geminivirus replicons to generate plants with a desired

153 tion of the tomato genome was achieved using geminivirus replicons, suggesting that these vectors can

154 le to native Cas9 when they are delivered on geminivirus replicons.

155 v. Othello) were identified by inoculating a geminivirus reporter (Bean dwarf mosaic virus expressing

156 The geminiviruses represent a family of DNA viruses that has

157 Effectively combatting diseases caused by geminiviruses represents a major challenge and opportuni

158 o virus X vector and that reversal of TGS by geminiviruses requires L2 function.

159 o movement proteins encoded by the bipartite geminivirus squash leaf curl virus, was immunolocalized

160 For the nuclear replicating bipartite geminiviruses such as squash leaf curl to systemically i

161 The movement of bipartite geminiviruses such as squash leaf curl virus (SqLCV) req

162 ruses, and suggest that SGS2/SDE1 may reduce geminivirus symptoms by targeting viral mRNAs.

163 Here, we used the geminivirus system to show that DRB3 is involved in meth

164 modate two newly discovered highly divergent geminiviruses that presently have no known vector.

165 Tomato leaf curl geminivirus (ToLCV) requires coat protein (CP) for the a

166 The geminivirus tomato golden mosaic virus (TGMV) amplifies

167 The genome of the geminivirus tomato golden mosaic virus (TGMV) consists o

168 The A genomic component of the geminivirus tomato golden mosaic virus (TGMV) contains a

169 e A component of the bipartite genome of the geminivirus tomato golden mosaic virus (TGMV) encodes th

170 The geminivirus tomato golden mosaic virus (TGMV) replicates

171 The geminivirus Tomato golden mosaic virus (TGMV) replicates

172 em where two nuclear-replicating agents, the geminivirus tomato yellow leaf curl Sardinia virus (TYLC

173 is a platform of constructs driven from the geminivirus Tomato yellow leaf curl virus.

174 The closely related geminiviruses tomato golden mosaic virus and bean golden

175 The replication proteins of the geminiviruses tomato yellow leaf curl virus and cabbage

176 nism of resistance and its durability toward geminiviruses under natural field conditions is discusse

177 methylation as an epigenetic defense against geminiviruses, using an RNA-directed DNA methylation (Rd

178 d missense tRNA(Lys) suppressor genes from a geminivirus vector capable of replication promoted 30-80

179 ng an autonomously replicating Agrobacterium/geminivirus vector have enabled identification of AU-ric

180 study, the tomato golden mosaic virus (TGMV) geminivirus vector was used to silence NbRBR1 in Nicotia

181 t five distinct species of cassava-infecting geminiviruses were capable of triggering PTGS by produci

182 DNAs comprised a Ds element that harbored a geminivirus, wheat dwarf virus (WDV), origin of replicat

183 virus (DSV) but not with another subgroup I geminivirus, wheat dwarf virus.

184 in planta for two distinct fully infectious geminiviruses with respect to the three replication mode