ライフサイエンスコーパス: gene expression signature

1 and embryonic stem (ES) cells share a common gene expression signature.

2 derived from a 91-gene HCC "venous invasion" gene expression signature.

3 n signalling pathway and absence of a T-cell gene expression signature.

4 etastatic cells possess a distinct stem-like gene expression signature.

5 and cannot be distinguished by a consistent gene expression signature.

6 germinal center reaction and its associated gene expression signature.

7 ll proliferation and an antigen presentation gene expression signature.

8 X10-infected NPCs was induced to a human OPC gene expression signature.

9 indolotriazine that is specified by a seven-gene expression signature.

10 ts and examined for correlation with the IFN gene expression signature.

11 NAPRT expression correlates with a BRCAness gene expression signature.

12 ontact inhibition and a strong Ewing sarcoma gene expression signature.

13 cal appearance, anatomical localization, and gene expression signature.

14 mponents was also validated using orthogonal gene expression signatures.

15 man bladder cancers, which displayed similar gene expression signatures.

16 capture of CTCs with the profiling of their gene expression signatures.

17 ients who can be identified and monitored by gene expression signatures.

18 s superior to evaluation of commitment-based gene expression signatures.

19 gene function and clinical predictions using gene expression signatures.

20 ecently reported biomarkers, with a focus on gene expression signatures.

21 ctivated B-cell (ABC)-like subtypes based on gene expression signatures.

22 al transcriptome shift from luminal to basal gene expression signatures.

23 , or other recently described stroma-derived gene expression signatures.

24 ommon and biologically meaningful prognostic gene expression signatures.

25 e modification, DNA methylation, and related gene expression signatures.

26 obtain RNA element-specific, high-resolution gene expression signatures.

27 ly correlated with GSC markers and stem cell gene expression signatures.

28 subjects was performed to identify distinct gene expression signatures.

29 function show enrichment for smoking-related gene expression signatures.

30 s prediction algorithms, as well as numerous gene expression signatures.

31 with high levels of ROR1 had stem cell-like gene-expression signatures.

32 ase states are connected by virtue of common gene-expression signatures.

33 We show that a Fra-1-dependent gene-expression signature accurately predicts recurrence

34 valuate functional convergence in epithelial gene expression signatures across multiple public access

35 CSCs have a significantly repressed IFN/STAT gene expression signature and an enhanced ability to mig

36 is classified by an extreme EpCAM(+) AFP(+) gene expression signature and associated with poor progn

37 We tested the relationship between this gene expression signature and both recurrence-free survi

38 13) AML is a rare entity defined by a unique gene expression signature and distinct clinical features

39 The gene expression signature and functional phenotype defin

40 Sensitive tumours exhibited a distinguishing gene expression signature and generally higher levels of

41 r translocation which induces a pro-survival gene expression signature and inhibits apoptosis.

42 correlated with enrichment of a mutated TP53 gene expression signature and of EGFR pathway genes.

43 e above findings, tumors harboring a TGFbeta gene expression signature and RUNX3 loss exhibited highe

44 Gene expression signature and surface marker analysis ha

45 e identified a palmitate-triggered ER stress gene expression signature and the induction of the BH3-o

46 ed that CD4+FOXP3+ T cells maintain the Treg gene expression signature and Treg-suppressive activity

47 Tuft cells have a Th2-related gene expression signature and we demonstrate that they u

48 Using whole transcriptome gene expression signatures and a computational bioinform

49 toma metastasis in vivo Overall, we identify gene expression signatures and candidate therapeutics th

50 We identified gene expression signatures and clinical data that are as

51 inct molecular groups of T-ALL with specific gene expression signatures and clinicobiological feature

52 Databases of perturbation gene expression signatures and drug sensitivity provide

53 protocols might influence epigenetic and/or gene expression signatures and hence might be less benef

54 active form of YAP (YAP(S127A)) and analyzed gene expression signatures and histomorphologic paramete

55 Ls fraction, tumor purity, adaptive immunity gene expression signatures and improved survival in Her2

56 scriptomic technologies make the analysis of gene expression signatures and mutation status possible

57 and produce proB cells with aberrant myeloid gene expression signatures and potential: features (coll

58 umor PET-FDG uptake features associated with gene expression signatures and survival.

59 anization is key to the establishment of new gene expression signatures and thus new cell identity.

60 We showed that our prognostic gene-expression signature and the one previously publish

61 RAS(G12V) enforced the leukemia self-renewal gene-expression signature and was required to maintain a

62 nscriptome throughout infection to establish gene-expression signatures and identify putative transcr

63 egard to cell metabolism, viability, growth, gene expression signature, and cytokine secretion.

64 ations between TSLP gene expression, a T(H)2 gene expression signature, and eosinophilic inflammation

65 C junction of the cervix, expresses a unique gene expression signature, and is not regenerated after

66 Given the superior prognostic value, unique gene expression signature, and significant value of CD30

67 ible chemokine score correlated with the IFN gene expression signature, and this score was higher in

68 os, to discover organizers based on a common gene expression signature, and use it to uncover the ant

69 es that vary in their genetic abnormalities, gene expression signatures, and prognoses.

70 Gene expression signatures are commonly used as predicti

71 In general, we find the aging gene expression signatures are very tissue specific.

72 rived CD200(+)/ITGA6(+) cells show a similar gene expression signature as EpSCs directly isolated fro

73 mutations on a new KRAS mutation-associated gene expression signature as well as previously defined

74 some features of the human immature/ETP-ALL gene expression signature, as well as an enhanced leukae

75 ted Smad1/5/8 and opposed the pro-angiogenic gene expression signature associated with ALK1 loss-of-f

76 Immunity, Krasemann et al. (2017) describe a gene expression signature associated with an APOE- and T

77 urvival of TAMs, but rather controls a novel gene expression signature associated with cytoskeleton r

78 to construct and interpret the differential gene expression signature associated with each common in

79 screen to identify drugs that can inhibit a gene expression signature associated with epithelial-mes

80 fatty acid oxidation ex vivo Remarkably, the gene expression signature associated with FoxO1 deacetyl

81 ross-validation analysis was used identify a gene expression signature associated with HGD vs nondysp

82 ed from highly susceptible cells, revealed a gene expression signature associated with susceptibility

83 ter androgen exposure identified a metabolic gene expression signature associated with the action of

84 CLUSIONS/SIGNIFICANCE: The identification of gene expression signatures associated to insecticide res

85 d with stromal cells cause underdetection of gene expression signatures associated with cancer progno

86 high levels of ROR1 were more likely to have gene expression signatures associated with EMT and had h

87 Analysis of the gene expression signatures associated with UC remission

88 biomarkers and is correlated with stem cell gene-expression signatures associated with adverse outco

89 w that sentinel methylation markers identify gene expression signatures at 38 loci (P < 9.0 x 10(-6),

90 A gene expression signature based on the top screening hit

91 Although gene-expression signature-based biomarkers are often dev

92 ference correlates with major differences in gene expression signature between subcutaneous and visce

93 BCL2 coexpression, there is no difference in gene expression signatures between the 2 subtypes in the

94 Transcriptome profiling reveals a gene expression signature broadly distinguishing stem ce

95 ere associated with a TH2-related epithelial gene expression signature, but expression of TH17-relate

96 The resulting data suggest that unique gene-expression signatures can distinguish between genet

97 Together with a gene expression signature characterized by IFN-I-induced

98 e progenitors (GMPs)], which have a distinct gene expression signature compared to wild-type (WT) mic

99 been associated with a unique immune-related gene expression signature composed of distinct chemokine

100 is for lung adenocarcinoma, and that a three-gene expression signature comprising TNC, S100A10, and S

101 lar signature in FSHD muscle together with a gene expression signature consistent with an immune cell

102 data with genomic data, we have identified a gene expression signature consisting of 13 up-regulated

103 perplasia-upregulated gene lists generated a gene expression signature consisting solely of module N5

104 ges, MGCs exhibited a specific phenotype and gene expression signature, consisting of increased cytos

105 eukemic cells, we defined a single cell core gene expression signature correlated to JAM-C expression

106 A dexamethasone-associated gene expression signature correlated with shorter surviv

107 A PB gene expression signature correlates with glycemic contr

108 r regulator inference algorithm (MARINA) and gene expression signature data from healthy and periodon

109 Gene expression signatures derived from ERG promoter-ste

110 These tumors are enriched in gene expression signatures derived from human tumor-init

111 ermore, our findings suggest that the airway gene expression signatures derived in this study can pro

112 using bioinformatics approaches to decipher gene expression signatures derived specifically from eit

113 How gene expression signatures differ among NSCs and immatur

114 We show that p-FLCs have a distinct gene expression signature different from that of m-FLCs,

115 NK1.1, CD49a, and CD103, these cells share a gene-expression signature distinct from those of convent

116 In this model, specific gene-expression signatures, distinctive upregulation of

117 trauma type revealed a clear pattern of PTSD gene expression signatures distinguishing interpersonal

118 In each patient, the overall gene expression signatures, DNA copy number patterns, an

119 scriptional output, loss of the HCL-specific gene expression signature, downregulation of the HCL mar

120 Transcriptomic analysis reveals a gene expression signature enriched for metabolic and imm

121 on of the RHO GTPase family, and regulated a gene expression signature enriched in cytoskeletal funct

122 ividuals with PC and Krt16 null mice share a gene expression signature enriched in genes involved in

123 high expression of ERBB3 with an epithelial gene expression signature; expression of TGFbeta correla

124 Cancer gene expression signatures extracted from individual dat

125 The increased DUOX2 and decreased APOA1 gene expression signature favored oxidative stress and T

126 development and assessment of a BRAF-mutant gene expression signature for colon cancer (CC) and the

127 An mRNA gene expression signature for COPD was identified in lun

128 The aim of this study was validation of a gene expression signature for distinguishing metastasizi

129 ained the inability to identify a predictive gene expression signature for docetaxel.

130 Consequently, a gene expression signature for suberin polymer assembly w

131 ts constitute a novel, biologically anchored gene expression signature for the identification of colo

132 Numerous prognostic gene expression signatures for breast cancer were genera

133 With computational analysis, core gene expression signatures for cDCs, MPs, and T and B ce

134 s to detect frozen tissue-derived prognostic gene expression signatures for CRC patients.

135 Here, we report that gene expression signatures for individual bees unrespons

136 g these proteins were previously included in gene expression signatures for outcome prediction for Ta

137 , and UBE2C have previously been included in gene expression signatures for outcome prediction in sta

138 ion, we demonstrate the feasibility of using gene expression signatures for the assessment of environ

139 ta-analysis was used to build a cross-tissue gene-expression signature for HPV-driven cancer.

140 genes bound by NHA9 and MLL1 and reverses a gene expression signature found in NUP98-rearranged huma

141 DP cells have a distinct gene expression signature from non-DP dermal fibroblasts

142 We identified a gene expression signature from zebrafish thyroid cancer

143 aggregate, and analyze themed collections of gene expression signatures from diverse but related stud

144 s unique to autism spectrum disorders; brain gene expression signatures from other honey bee behavior

145 ing to develop prognostic, morphology-based, gene expression signatures from the vascular architectur

146 We have interrogated a 12-chemokine gene expression signature (GES) on genomic arrays of 14,

147 Clinical application of the prognostic gene expression signature has been delayed due to the la

148 and for a major part of their characteristic gene expression signature; however, it remains unknown t

149 by chromosomal abnormalities and an altered gene expression signature; however, the mechanism of CIN

150 A novel gene expression signature identified severely injured he

151 SOX4, and SOX11 along with the SOX4-specific gene expression signature identified.

152 analysis of aggregated collections of tagged gene expression signatures identified and extracted from

153 ile only rapamycin perturbed the healthy-age gene expression signature in a manner consistent with in

154 erations of PPARG or RXRA lead to a specific gene expression signature in bladder cancers.

155 resting markers described recently include a gene expression signature in CD8+ T cells that predicts

156 nction in human lung tumors, we identified a gene expression signature in human lung adenocarcinoma c

157 The gene expression signature in invasive breast cancer was

158 lories BMI would be associated with a unique gene expression signature in motor regions of the brain

159 that LMP1 is important to establish the Hox gene expression signature in NPC cell lines and tumor bi

160 Interestingly, the gene expression signature in p53-deficient hearts confer

161 elegans wild isolate, JU1580, has a distinct gene expression signature in response to viral infection

162 n design, we discovered and validated a four-gene expression signature in whole blood, indicative of

163 ns, immunophenotypic markers, and microarray gene expression signatures in a panel of 53 adult T-ALL

164 we developed and validated pathway-specific gene expression signatures in bronchial airway epitheliu

165 We compared gene expression signatures in inflamed vs noninflamed in

166 ive miRNAs that are associated with temporal gene expression signatures in macrophages early after Mt

167 The findings suggest that distinct gene expression signatures in pathologic gingival tissue

168 r analysis reveals that previously disclosed gene expression signatures in TB show highly similar pat

169 oarray revealed that IGF1 activated distinct gene expression signatures in the 2 Sox9-EGFP ISC popula

170 We identify a "NOTCH1 gene-expression signature" in CLL cells, and show that t

171 Here we test the hypotheses that skin gene expression signatures including intrinsic subset ar

172 sted several compounds that reverse the COPD gene expression signature, including a nicotine receptor

173 mab) showed upregulation of an IFNG-response gene expression signature, including CTLA4 itself, which

174 iation between xenograftability and a unique gene expression signature, including down-regulated PTEN

175 y-6C(low) macrophages with a skewed M2-prone gene expression signature, increased collagen deposition

176 sion was found to correlate with the hypoxia gene expression signature, increasing tumor grade, and r

177 Damaged mitochondria accumulated, and gene expression signatures indicated attempted axonal re

178 latter displaying biological responses and a gene expression signature indicative of chronic TPO over

179 Emu-Tcl1 murine model of CLL, we identified gene expression signatures indicative of a skewed polari

180 rofiling of mouse and human AA skin revealed gene expression signatures indicative of cytotoxic T cel

181 onhematopoietic cells exhibited a strong IFN gene-expression signature, irrespective of genotype.

182 lifetime and discovered that the AD-related gene expression signature is age-independent.

183 and failed to address whether the identified gene expression signature is disease-specific or more wi

184 INTERPRETATION: The peripheral blood 52-gene expression signature is predictive of outcome in pa

185 In addition, an MET gene expression signature is prognostic for improved ove

186 Using an existing 50-gene expression signature known to separate two molecula

187 ultiple measurements, including induction of gene expression signatures, morphological changes, and c

188 erentially expressed genes were reduced to a gene expression signature of 113 genes.

189 wo replication sets (n = 285 and 224), and a gene expression signature of 599 transcripts consistentl

190 A sputum gene expression signature of 6 biomarkers reproducibly a

191 We further define a gene expression signature of anergic CLL cells consistin

192 hagy, repression of E2F target genes, and an gene expression signature of blocked DNA methylation.

193 Conversely, we identified a gene expression signature of CALR mutations; this signat

194 Overall, the gene expression signature of CCR6(+)CXCR3(+)CCR4(-) cell

195 sought to determine whether the inflammatory gene expression signature of CHIKV arthritis shows any s

196 bal suppression of transcription, maintain a gene expression signature of diapaused blastocysts and r

197 The gene expression signature of HCC-bearing livers is simil

198 syndrome AMKL and strongly associated with a gene expression signature of Hedgehog pathway activation

199 oinformatic cross-species comparison using a gene expression signature of MPNST-like mouse melanomas

200 nal cord of Zfp106 knockout mice displayed a gene expression signature of neuromuscular degeneration.

201 In this study, we describe a novel gene expression signature of platelet-derived growth fac

202 strategy to identify compounds opposing the gene expression signature of STAT3, we discovered atovaq

203 nd physiological phenotyping, identified the gene expression signature of the response and revealed h

204 phagy induction and restored the hippocampal gene expression signature of the Tg2576 mice to wild-typ

205 experimentally generated, pancreas-specific gene expression signature of Wnt/beta-catenin transcript

206 in vitro differentiation system, we defined gene expression signatures of distinct progenitor popula

207 enous DUX4-and show that the DUX4-associated gene expression signatures of each dataset are highly co

208 To map the microRNA/gene expression signatures of EPC senescence, we perform

209 egrated genomic strategy based on the use of gene expression signatures of oncogenic pathway activity

210 erated M. lignano transcriptome assembly and gene expression signatures of somatic neoblasts and germ

211 pple-specific signaling factors, we compared gene expression signatures of sorted Pdgfralpha-positive

212 actor-beta (TGFbeta) signaling and exhibited gene expression signatures of stemness, TGFbeta signalin

213 17A or interferon-gamma showed an overlap of gene expression signatures of Th17 or Th1 cells and of T

214 The gene expression signatures of these murine HGGs reflecte

215 Cellular Signatures), a database containing gene expression signatures of thousands of compounds, to

216 Analysis of the gene expression signatures of tumor cell lines showed an

217 with protective memory cells we compared the gene expression signatures of two qualities of memory CD

218 y and validation of genetic determinants and gene expression signatures of various chemotherapeutic s

219 Gene-expression signatures of good and poor prognosis we

220 e are consistent differences in mutation and gene-expression signatures of head and neck and lung SCC

221 hat SCL and c-Kit signaling control a common gene expression signature, of which 19 genes are associa

222 ematic fashion, by taking into consideration gene expression signatures or chemical features for inst

223 In the gene expression signature patterns elicited by SBI-756,

224 CAF-induced gene expression signatures predicted clinical outcome an

225 ould be monitored with a previously reported gene expression signature predictive of HCC risk in huma

226 Gene-expression signatures predictive of eventual fates

227 a distinct ALL subtype with a characteristic gene expression signature predominantly driven by chromo

228 at 14q22.1, mutations in KRAS and BRAF, and gene expression signatures previously associated with po

229 A gene expression signature, prognostic for prostate-speci

230 ffects were further associated with specific gene expression signatures reflecting pathway inhibition

231 s, there was an inverse relationship between gene expression signatures regulated by PI3K signaling a

232 nalysis and information gain identified a 14 gene expression signature related to the 9VF's.

233 We demonstrated that gene expression signatures related to a poor-prognosis H

234 Gene expression signatures relating mammary stem cell po

235 A 140-gene expression signature reliably stratified patients w

236 h as TP53 mutations, expression of IRF4, and gene expression signatures reminiscent of dark zone germ

237 e accurately predicted patient outcomes than gene expression signatures reported previously.

238 fibroblasts into iOPCs with morphologies and gene expression signatures resembling primary OPCs.

239 ession of multiple cell cycle genes, and the gene expression signature resulting from ERH down-regula

240 while Vitamin E induced a pro-proliferative gene expression signature, Selenium alone or combined wi

241 Gene expression signature sets were validated using gene

242 Finally, we uncover a growth promotion gene expression signature shared between different devel

243 Accordingly, tumor gene expression signatures specific for myeloid cell che

244 We previously used Gene Expression Signature technology to identify methazo

245 s of ASCL1, we discovered an ASCL1 target 72-gene expression signature that (i) identifies neuroendoc

246 Murine Terc(-/-) LSCs express a specific gene expression signature that can be identified in huma

247 we report on a validated and highly accurate gene expression signature that can be reliably used to i

248 tudy aimed to identify and validate a sputum gene expression signature that discriminates asthma infl

249 utant) AMLs did not express a methylation or gene expression signature that discriminates them from p

250 AC causes tumor cell responses and exposes a gene expression signature that implicates MAC as a drive

251 SOX4-amplified lung cancer cells revealed a gene expression signature that included genes involved i

252 nts also inhibit the expression of a hypoxia gene expression signature that is associated with decrea

253 We have defined and validated a new gene expression signature that is independent of drug ef

254 rammed in 6 d and express a unique miRNA and gene expression signature that is similar but not identi

255 profiles defined by a hypothalamic-specific gene expression signature that lacked pituitary markers.

256 regulated genes, we defined a robust IFNbeta gene expression signature that quantifies the IFN activa

257 In a complementary approach, we identified a gene expression signature that was associated with reduc

258 patients with TNBC revealed a specific XBP1 gene expression signature that was highly correlated wit

259 the unannotated class (23% of samples) had a gene expression signature that was not associated previo

260 lular phenotype, which led to isolation of a gene expression signature that was predictive of surviva

261 Gene expression signatures that are predictive of therap

262 and invasive states, which have identifying gene expression signatures that correlate with good and

263 he genetic background to generate prognostic gene expression signatures that illuminate regulators of

264 SC) phenotypes based on growth potential and gene expression signatures that represent oncogenic sign

265 yielded classical (Ly6C(hi)) monocytes with gene expression signatures that were defined by their or

266 at whole-blood gene profiling could identify gene-expression signatures that stratify patients with c

267 An early immature gene expression signature, the absence of bi-allelic TCR

268 We aimed to develop and validate a gene expression signature to predict which patients woul

269 We aimed to develop and validate a gene expression signature to suggest which patients woul

270 Review remains relevant in the era of gene expression signatures to determine margin and nodal

271 ression data' (ESTIMATE)--a method that uses gene expression signatures to infer the fraction of stro

272 escribed an assay called ScoreCard that used gene expression signatures to quantify differentiation e

273 determined whether diseased livers express a gene expression signature unique to BA.

274 in situ sampling of apoptotic IECs revealed gene expression signatures unique to each phagocyte, inc

275 varian cancer-specific IKK-epsilon-regulated gene expression signature using stably expressed short h

276 sed Cellular Signatures (LINCS) project many gene expression signatures using the L1000 technology ha

277 In contrast, a basal-like gene expression signature was better at predicting OSmet

278 Furthermore, a FOXC2-induced gene expression signature was enriched in the claudin-lo

279 A Sirt6 knockout (KO) gene expression signature was generated from primary hep

280 ndence of urothelial carcinoma cell lines, a gene expression signature was identified that correlated

281 00E)Braf in the double-mutant cells, and the gene expression signature was more similar to that induc

282 An HSP27-associated gene expression signature was related to molecular subgr

283 This E2f3 TAM gene expression signature was sufficient to predict canc

284 clinically relevant colorectal cancer (CRC) gene expression signatures, we assessed the susceptibili

285 Additionally, two distinct in vivo splenic gene-expression signatures were induced.

286 fector cells displayed a stronger pro-memory gene expression signature, whereas the gene expression p

287 as associated with a specific pro-angiogenic gene expression signature, which included a significant

288 Coco induces a discrete gene expression signature, which is strongly associated

289 ce, we generated a consensus CHIKV arthritis gene expression signature, which was used to interrogate

290 herapy from these patients revealed distinct gene expression signatures, which correlated with their

291 ied 32 anatomically diverse and reproducible gene expression signatures, which represent distinct cel

292 as (TCGA), we developed subtype and survival gene expression signatures, which, when combined, provid

293 rigenesis, and the tumours share a conserved gene expression signature with beta-catenin-positive hum

294 ere we used tomo-seq to obtain a genome-wide gene expression signature with high spatial resolution s

295 bitor of mTOR, INK128, which reprograms this gene expression signature with therapeutic benefit for p

296 onal status, are characterized by a distinct gene expression signature with upregulation of JAK-STAT

297 into two main subgroups, one of which shared gene expression signatures with previously identified he

298 ng lymphocytes share a core tissue-residency gene-expression signature with TRM cells that is associa

299 ighly statistically significant and distinct gene expression signature, with coordinate overexpressio

300 associated with distinct and nonoverlapping gene expression signatures within the HSC compartment.