ライフサイエンスコーパス: gene family

1 n the glucose transporter family (GLUT, SLC2 gene family).

2 t small subunits (RbcS) encoded by a nuclear gene family.

3 etworks, which include the distal-less (Dlx) gene family.

4 al members of the prolyl 3-hydroxylase (P3H) gene family.

5 to the vapBC (virulence associated protein) gene family.

6 SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) gene family.

7 enome, in this case, in paralogs of the same gene family.

8 ary changes in two other members of the same gene family.

9 of GAL4 driver lines of the Ir, Gr, and Ppk gene family.

10 falciparum is mediated by the multicopy var gene family.

11 nts each component is represented by a large gene family.

12 cating that ASG2 is a member of the spidroin gene family.

13 e OsSWEET11, a member of sucrose transporter gene family.

14 tor of differentiation (ID) helix-loop-helix gene family.

15 we analyze functional divergence in the WOX gene family.

16 ller cell immunoglobulin-like receptor (KIR) gene family.

17 on directed by a distinct member of the same gene family.

18 e expansion and evolution of this very large gene family.

19 subsequent differential expansion of each R gene family.

20 ary dynamics of this agronomically important gene family.

21 nging to the amyloid precursor protein (APP) gene family.

22 ation of the moss Physcomitrella patens PTEN gene family.

23 by a highly conserved and broadly expressed gene family.

24 diverse plant phyla, and fall within the IGT gene family.

25 of the cAMP Response Element Binding protein gene family.

26 uped into the same B. burgdorferi paralogous gene family.

27 dicating functional redundancy in this large gene family.

28 ating an exclusive retrograde impact on this gene family.

29 duplication-loss and coalescent history of a gene family.

30 k-down of genes belonging to the cathepsin B gene family.

31 ily, or by KCl cotransporters from the SLC12 gene family.

32 apping or fluid functional evolution of this gene family.

33 are linked to radiations of lineage-specific gene families.

34 between the well-known legume and cereal BBI gene families.

35 ulation of genes belonging to aphid-expanded gene families.

36 ling large expansion within protein encoding gene families.

37 lant species, referred to as angiosperm core gene families.

38 increased levels of specialization in larger gene families.

39 reveal substantial expansion of subtelomeric gene families.

40 regulation of various metabolic pathways and gene families.

41 ontributed significantly to the expansion of gene families.

42 at contributed to the generation of expanded gene families.

43 ndoderm specification and at the Hox and Fox gene families.

44 e expression changes within the ISG and Bcl2 gene families.

45 CF1/2) and members of the NGATHA and STYLISH gene families.

46 silk-specific genes belong to multi-paralog gene families.

47 ts led to distinct Class I and Class II KNOX gene families.

48 llection of approximately 13 000 prokaryotic gene families.

49 ving and belong to large Nematocida-specific gene families.

50 lele in the Tmc1 (transmembrane channel-like gene family 1) Beethoven (Bth) mouse model, even though

51 ylanase belonging to the glycoside hydrolase gene family 11 (GH11) was obtained from the ascomycete T

52 omes contained a core set of 103 orthologous gene families absent from all other ammonia-oxidizing ar

53 FMAP performs alignment, gene family abundance calculations, and statistical anal

54 genes Dicer, Dgcr8, and the entire Argonaute gene family (Ago1, 2, 3, and 4).

55 Gene family analyses reveal lineage-specific duplication

56 identified 1,970 homologs of established SSP gene families and an additional 2,455 genes that are pot

57 trols the repression of multi-copy virulence gene families and determines sexual stage commitment.

58 de-repeat (TPR) domains are encoded by large gene families and distributed in all plant lineages.

59 dances of the antimicrobial resistance (AMR) gene families and enables accurate characterization of t

60 Analyses of clustered gene families and gene collinearity show that jute under

61 he deep phylogeny of eukaryotic CS converter gene families and identified a phylogenetically and stru

62 Here, we survey duplicate gene families and identify converted tracts in 46% of th

63 utionary dynamics, promoting co-evolution in gene families and maintaining similarities between repea

64 cations that occurred in most starch-related gene families and resulted in subfunctionalization of th

65 the evolution and possible function of large gene families and specifically, the defensins.

66 cell antigen (Sca) -1 is a member of the Ly6 gene family and a known marker of stem cells in both hem

67 thus identifies a new d-amino acid racemase gene family and advances our knowledge of plant d-amino

68 gation factor/small rubber particle protein) gene family and its divergence into several laticifer-sp

69 We postulate that expansion of the ncHLI gene family and its regulation may reflect the light/oxi

70 e we report characterization of soybean WRKY gene family and their functional analysis in resistance

71 s are detailed in annotations, comparable by gene families, and BLAST-searchable by user provided seq

72 t applications (e.g. plant genomics, ancient gene families, and others) and the infrastructure for ma

73 oires of antiviral interferon (IFN) cytokine gene families, and our results indicated that in compari

74 ded annotations of the chemosensory receptor gene families, and provide first-time transcript abundan

75 All LOX belong to the same gene family, and they are widely distributed.

76 in regulation of parasite-specific genes and gene families are examined.

77 Prolamin and resistance gene families are important in wheat food use and in def

78 Here, we identified which gene families are most strongly reciprocally retained in

79 Olfactory receptor gene families are significantly expanded in pangolins, r

80 free-living stages and find that these same gene families are upregulated in the parasitic stages, u

81 the Family with sequence similarity (FAM) 20 gene family are associated with mineralized tissue pheno

82 n, members of the distal-less (Dlx) homeobox gene family are expressed in, and regulate the developme

83 New gene functions arise within existing gene families as a result of gene duplication and subseq

84 Instead, the HsOR gene family as a whole responds to a broad array of comp

85 a member of the Bric-a-Brac/Tramtrack/Broad gene family, as the most central and connected gene in t

86 0,486 protein-coding genes and expansions of gene families associated with tick-host interactions.

87 suggests that the expansion of one B subunit gene family (B56/PPP2R5) was driven by functional divers

88 n of gene duplicability across species, with gene families being either primarily single-copy or mult

89 n tested in a reliable, extensive, and cross-gene family benchmark, REMAP outperforms the state-of-th

90 most widely accepted gene-specific and cross-gene family benchmarks and demonstrate that our method o

91 nscriptional modules often regulate the same gene families but control different individual members o

92 PfEMP1 is encoded by a large multi-gene family called var.

93 Some alleles of the wtf gene family can increase their chances of spreading by u

94 hox and dlx clusters and in the tbx and pitx gene families, candidate mechanisms for the evolution of

95 bility Complex (MHC) region contains several gene families characterized by highly polymorphic loci w

96 resentative IFN genes, belonging to distinct gene family clades, as well as their cognate receptor ge

97 Discovery and characterisation of the gene family coding the olfactory receptors contributed t

98 The Arabidopsis (Arabidopsis thaliana) CDA gene family comprises nine members, one of which (AtCDA)

99 racellular Cys-rich domains and constitute a gene family consisting of 46 members in Arabidopsis.

100 -of-function somatic mutations of the same 5 gene families damage the microvasculature of the brain t

101 ripts and phylogenetic reconstruction of 605 gene families demonstrated conservation of expression fo

102 , we show how species-specific, cell-surface gene families (DGF-1 and PSA) with no apparent structura

103 he STs also display substantial variation in gene family distributions and sizes, especially for prot

104 All these gene families emerged in green algae and show concurrent

105 f NKG2DL genes have been identified: the MIC gene family encoded in the MHC region and the ULBP gene

106 amily encoded in the MHC region and the ULBP gene family encoded outside the MHC region in most speci

107 The VAL gene family encodes repressors of the seed maturation pr

108 eliable serial genetic dissection of a large gene family encoding novel calcium-dependent protein kin

109 To investigate whether gene family evolution has contributed to the genome down

110 mes that should broaden our understanding of gene family evolution.

111 nteny analysis can provide new insights into gene family evolution.

112 lata are conserved, suggesting that this TPS gene family evolved from trans-IDS ancestors.

113 Reciprocally retained gene families exhibit stronger sequence divergence const

114 ead we found active (retro)transposition and gene family expansion, especially in processes important

115 rs to study the lineage specificity of these gene family expansions and the distinct evolution of gen

116 ontent reconstruction to track the timing of gene family expansions for the major families of ion-cha

117 other cucurbits, as well as lineage-specific gene family expansions in bottle gourd.

118 lipid uptakes, and differential/specialized gene family expansions in T. asiatica that may favour it

119 results also suggest that most bean-specific gene family expansions, including resistance gene cluste

120 nia-oxidizing archaea and, for most of these gene families, expression could be demonstrated in labor

121 A significant paralogous expansion of key gene families--families encoding astacin-like and SCP/TA

122 The largest known arthropod gene family (family SSGP-71) was also discovered within

123 invasiveness and host adaptation, including gene families for chemoreception, toxin and insecticide

124 In addition to a clear contraction in gene families for starch and sucrose metabolism, the car

125 predict off-target interactions in the same gene family for hundreds of chemicals.

126 functionally characterize members of the CHS gene family from Rheum emodi, an endangered and endemic

127 s considerable lineage-specific expansion of gene families functionally enriched in the adaptability

128 Gene families functioning in regulatory and signaling pr

129 In soybean, five members constitute the SNAP gene family: GmSNAP18, GmSNAP11, GmSNAP14, GmSNAP02, and

130 This gene family has been recently shown to introduce-in mult

131 roteins (NLRs), the major disease-resistance gene families, has been unexplored in plants.

132 in-1 (NAC1), a nuclear factor of the BTB/POZ gene family, has emerging roles in cancer.

133 achidonic acid pathway, membrane-spanning 4A gene family, histamine production pathway, and pro-infla

134 ted a potential regulatory role for the Hox5 gene family, Hoxa5, Hoxb5, and Hoxc5, genes known to be

135 gulation of downstream evolutionary expanded gene families important for placental and hypothalamic d

136 analyzed the soybean trypsin inhibitor (STI) gene family, important plant defense genes, in the conte

137 construct the evolutionary histories of PP2A gene families in Arabidopsis (Arabidopsis thaliana).

138 indicate that the expansion of PP2A subunit gene families in both flowering plants and animals was d

139 l antiapoptotic members of the BCL2 and BIRC gene families in CML cells, including the long isoform o

140 The presence of these gene families in higher plants points to the existence o

141 sphatidylethanolamine-binding protein (PEBP) gene families in non-flowering plants, we performed a fu

142 titute one of the largest and most conserved gene families in plant, and play essential roles in grow

143 The Ly49 and KIR gene families in rodents and humans encode both inhibito

144 Comparative analysis of tRNA gene families in sequenced Pentatomomorpha and Lygaeoide

145 that they are encoded by one of the largest gene families in the human genome has come to the fore r

146 The importance of the Hox gene families in vertebral development was highlighted a

147 first time the comprehensive analysis of TCP gene family in a diploid cotton species, Gossypium arbor

148 ors (ORs) encoded by a dramatically expanded gene family in ants.

149 port on genome-wide characterization of this gene family in cotton.

150 s have unveiled diverse roles of the FT/TFL1 gene family in developmental processes other than flower

151 ncogenes make up the most frequently mutated gene family in human cancer.

152 a wider role for the inhibitor of apoptosis gene family in IBD pathogenesis.

153 ontribute to our understanding of this large gene family in insects, we have investigated the functio

154 We investigated the dio gene family in juvenile Atlantic salmon (Salmo salar) pa

155 An example of such a case is the protein gene family in maize that acts as a sink for reduced nit

156 While PSY constitutes a small gene family in most plant taxa, the Brassicaceae, includ

157 iquitin-like protease class of SUMO protease gene family in rice (Oryza sativa) and demonstrate a cri

158 ides the first comprehensive analysis of TCP gene family in the cassava genome.

159 However, little is known about this gene family in the important tropical crop cassava (Mani

160 uggesting a similar biological role for this gene family in this species.

161 functional diversification in the Rab GTPase gene family in three Paramecium aurelia species.

162 N13 belongs to a Paspalum gene family including 30-60 members, of which at least e

163 e comprises 6 categories of approximately 40 gene families, including cell-adhesion molecules, transm

164 s and radiations in all major detoxification gene families, including P450 monooxygenases, carboxyl/c

165 that express chemoreceptors encoded by large gene families, including the odorant receptors (ORs) and

166 how that the genome duplication has expanded gene families, including those involved in signal transd

167 cations have contributed to the expansion of gene families, including those with roles in flowering t

168 bers of the ether-a-go-go (EAG) K(+) channel gene family, including EAG1 (Kv10.1), ERG3 (Kv11.3), and

169 rom leaf and fruit and identified members of gene families involved in intermediate steps of terpenoi

170 nal redundancy, while adaptive radiations of gene families involved in membrane function provide the

171 C3 plants, with an emphasis on comparing 13 gene families involved in the complete carbon fixation p

172 ed to the simplification of many orthologous gene families involved in the saprophytic trophic mode,

173 istinction between single-copy and multicopy gene families is reflected in their functional annotatio

174 ceptible parents, the divergence of the SNAP gene family is analysed over time.

175 The mouse OR gene family is composed of approximately 1000 OR genes,

176 pproximately 1000 OR genes, and the human OR gene family is composed of approximately 400 OR genes.

177 he Arabidopsis (Arabidopsis thaliana) PI-PLC gene family is composed of nine members.

178 The KIR gene family is highly polymorphic and not well captured

179 However, how the KANK gene family is involved in vascular vessel development d

180 The human member of this gene family is mutated in most cancers, but precisely ho

181 Expansion of the cytochrome P450 gene family is often proposed to have a critical role in

182 ng the evolutionarily generated members of a gene family is pivotal in driving the chemical diversity

183 The multiprotein-bridging factor 1 (MBF1) gene family is well known in archaea, non-lichenized fun

184 brachyury, the founding member of the T-box gene family, is a key gene in chordate mesoderm developm

185 ed five amplified regions, each containing a gene family known to be involved in mammalian placentati

186 SLC39A8 is a member of the solute carrier gene family known to import Mn, Zn, and other divalent c

187 ed induction of several members of the YUCCA gene family, leading to auxin production in the cotyledo

188 content, evaluate copy number of ampliconic gene families, locate species-specific palindromes, exam

189 fected cells, phosphorylation of Ras homolog gene family member A (RhoA) and vasodilator-stimulated p

190 ontrast, inactivation of RhoA (Ras homologue gene family member A) signaling leads to vessel overexpa

191 otulinum toxin substrate 1 and Ras homologue gene family, member A (RhoA) guanine nucleotide exchange

192 ta et al reported that different Ras homolog gene family, member A (RHOA) hotspot mutations among the

193 relates with increased levels of Ras homolog gene family, member A (RhoA), a KCTD13/CUL3 ubiquitin li

194 ein kinase), downstream of RhoA (Ras homolog gene family, member A), stabilized moesin and directiona

195 CD altered the Ras homolog gene family, member A/Rho-associated kinase pathway with

196 lators include the family of Neuron-Specific Gene family members (Nsg), NEEP21 (Nsg1), and P19 (Nsg2)

197 These results indicate BT gene family members act as conserved negative regulators

198 gous recombination (NAHR) between ATAD3A and gene family members ATAD3B and ATAD3C.

199 expression of all 18 carotenogenic genes or gene family members examined, or sequence or abundance o

200 HOX genes, the role of nonclustered homeobox gene family members in hematopoiesis and leukemogenesis

201 hly conserved in the plant kingdom with five gene family members in maize and homologs even among ear

202 d with tetratricopeptide repeat motif (IFIT) gene family members share structural features at the gen

203 Gene family members tended to be mapped on the same chro

204 es (including cytokines, chemokines, and p53 gene family members) as bona fide downstream transcripti

205 re enhanced by inhibitor of DNA binding (Id) gene family members, Id1, Id2 and Id3, which can be high

206 cal conservation, and divergence of MADS-box gene family members.

207 mechanisms of functional divergence between gene family members.

208 (GRCD) genes, including previously unstudied gene family members.

209 e expansion and diversification of most PP2A gene families, members of functionally specialized subcl

210 icroRNA BLINDBEN belongs to the TOE-type AP2 gene family, members of which control flowering time in

211 antigens, encoded by members of a multicopy gene family named var.

212 s seen in the WUSCHEL-RELATED HOMEOBOX (WOX) gene family, named after the Arabidopsis stem cell regul

213 of other plant species identified a new RDR gene family, not present in potato and found only in Ros

214 Although the Cellulose Synthase (CESA) gene families of mosses and seed plants diversified inde

215 Yet, compared to other gene families of similar stature, SLCs are relatively un

216 The EGG CELL1 (EC1) gene family of Arabidopsis (Arabidopsis thaliana) compri

217 VPS13 is the founding member of a eukaryotic gene family of growing interest in cell biology and medi

218 belong to the solute carrier 24 (SLC24A1-5) gene family of membrane transporters.

219 Tbx15 is a member of the T-box gene family of mesodermal developmental genes.

220 ily of PDIs that represents the most diverse gene family of oxidoreductases described in a single gen

221 conserved sequence specific for the sicavar gene family of Plasmodium knowlesi.

222 Odorant receptors (ORs) belong to a large gene family of rhodopsin-like G protein-coupled receptor

223 orm in terms of detecting off-targets across gene families on a proteome scale.

224 tional redundancy has evolved among expanded gene families operating at the parasite-host interface.

225 The ten-eleven translocation (TET) gene family oxidizes 5mC to 5-hydroxymethylcytosine (5hm

226 urgdorferi genome harbors several paralogous gene families (pgf) that can encode immunogenic proteins

227 The resulting gene family phylogeny of CMT transcripts from the most d

228 The gene family plexins, members of which are mutated in sev

229 ntified, greatly expanding the number of SSP gene families potentially involved in acclimation to nut

230 ome-wide analysis also identified members of gene families putatively involved in secondary modificat

231 mmonalities that promote infection, specific gene-family radiations contribute to distinct infection

232 S2 is a member of the Vps10p-domain receptor gene family receptors with critical roles in the control

233 xtreme rates of gene turnover, especially in gene families related to olfactory communication, such a

234 f the entire aminoacyl-tRNA synthetase (ARS) gene family revealed that 16/20 of the genes encoding cy

235 amily consists of four functionally distinct gene families (Shaker, Shab, Shal, and Shaw) that share

236 epresents a comprehensive set of orthologous gene families shared across multiple complete genomes of

237 we investigated duplicate retention for 9178 gene families shared between 37 flowering plant species,

238 An exact solution for the dynamics of gene family size was obtained under a linear duplication

239 rt transcripts, overlapping gene models, and gene family size.

240 s study we demonstrate that, within the SMXL gene family, specifically SMXL3/4/5 deficiency results i

241 spin-off projects in developmental biology, gene family studies, and neuroscience.

242 w that the functional diversification of key gene families such as DCL and AGO as observed in angiosp

243 st that members from ancient and polymorphic gene families such as defensins and receptor-like kinase

244 and copy number variation in the two latter gene families, suggesting an adaptive role for structura

245 ctional and expression divergence than other gene families, suggesting that dosage balance sensitivit

246 Molecular dating analysis of the Cpt gene family suggests that a horizontal gene transfer eve

247 Novel gene families that are not well studied in other arthrop

248 An intermediate class contains gene families that are often retained in duplicate for p

249 biologically relevant compound, and several gene families that can alleviate guanidine toxicity exis

250 cludes two classes of nodes, the genomes and gene families that connect them.

251 ent in only one of the two genotypes and 136 gene families that have undergone extensive expansion or

252 t of copy number variation in multicopy ChrY gene families that influence susceptibility to other imm

253 ihydrofolate reductase-thymidylate synthase) gene family that implements the penultimate step in fola

254 ed antigen A1 (MAGEA1) is member of the MAGE gene family that is expressed in male germ line cells an

255 form an uncharacterized subclade of the SMXL gene family that mediates hormonal strigolactone and kar

256 viously, 41-48 gene copies of the alpha zein gene family that spread over six loci spanning between 3

257 ta contains a highly divergent 17-member OBP gene family, that includes an ant-specific expansion and

258 tter understand the evolution of these multi-gene families, the DNA sequence of a 2.8-Mb genomic regi

259 etic diseases and the concerted evolution of gene families, the parameters that govern NAGC are not w

260 ter understand the evolution of this complex gene family, the DNA sequence of a 1.75-Mb genomic regio

261 but rather is part of a widespread arthropod gene family, the peritrophic matrix proteins.

262 nferring the evolutionary history of a given gene family; this pipeline can model gene sequence evolu

263 trate that AA availability modulates the ARS gene family through modulation of transcription elongati

264 quenced legume species and provides a set of gene families to allow traversal among orthologous and p

265 and gene losses contained in 31,236 archaeal gene families to identify the most likely root for the t

266 lization of the ancestral diterpene synthase gene family to >400 million years ago.

267 proposed that FRIENDLY expanded into a small gene family to help regulate the energy metabolism of ce

268 the risk susceptibility by the gamma subunit gene family to SCZ, we conducted a large-scale associati

269 L3, members of the type III interferon (IFN) gene family, to support viral persistence.

270 Within the tomato MADS-box gene family, TOMATO AGAMOUS1 (TAG1) and ARLEQUIN/TOMATO

271 Gene family trees were constructed to identify homologs

272 d Ig repertoire, with predominant VH4 or VH5 gene family usage and Env V3 specificity.

273 clusters of somatic mutations across entire gene families using protein domain models.

274 etworks of the MADS-box transcription factor gene family using 51 completed plant genomes.

275 We compared the effect of OAS gene family variants on 2 DENV serotypes in cell culture

276 a method for examining the effects of multi-gene families via simultaneous gene knockdown.

277 for inferring the evolutionary history of a gene family was developed, and its application was demon

278 boring multiple prolamin and resistance-like gene families, was analyzed in the diploid grass Aegilop

279 For most gene families, we observe a strikingly consistent patter

280 h the resolution is very poor for individual gene families, we show that genome-wide data sets are su

281 gain insight into the function of this large gene family, we developed an antibody that recognizes th

282 c analyses indicated that four of these core gene families were acquired by the Ca.

283 sions involving ALK, ROS, RET, NTRK and FGFR gene families were detected in bladder carcinoma (3.3%),

284 ngation factor/small rubber particle protein gene families were expanded independently from the H. br

285 A total of 149 immune-related genes in 20 gene families were identified through comparison of P. x

286 ncing data obtained from a malaria virulence gene family, where Multipass generates 20 % more error-f

287 ression of the members of WRKY, MYB and BHLH gene families, which are involved in the Fe and other es

288 f the NKRP1 and C-type lectin-like 2 (CLEC2) gene families, which constitute genetically linked recep

289 , especially for protein kinase and protease gene families, which could reflect differences in virule

290 tified the entire soybean (Glycine max) CIPK gene family, which comprised 52 genes and divided into f

291 plied this pipeline to the STIMATE (TMEM110) gene family, which has recently been reported to play an

292 Klhl6 belongs to the KLHL gene family, which is composed of an N-terminal BTB-POZ

293 Hoxa5 is a member of the Hox gene family, which plays critical roles in successive st

294 d by an ampliconic region including the HSFY gene family, which together make up most of the short ar

295 arkable expansions of protease and cell wall gene families, while divergent infection strategies are

296 This resource was used to investigate gene families with key functions that could be potential

297 contrast these complete CLE peptide-encoding gene families with those of fellow legumes, Glycine max

298 t cultures indicated the presence of a large gene family (with 20 members) for terpene synthases (TPS

299 This gene family, with a proposed new name, Calmodulin Fused

300 iation of the Kunitz trypsin inhibitor (KTI) gene family within winged bean.