ライフサイエンスコーパス: gene manipulation

1 animals is the capability to perform in vivo gene manipulation.

2 newing XEN cells without the requirement for gene manipulation.

3 bility to determine protein function through gene manipulation.

4 patial and temporal control over the desired gene manipulation.

5 the use of artificial culture conditions or gene manipulations.

6 TFs) or nucleases (TALENs), enabling precise gene manipulations.

7 Gene manipulation and pharmacological approaches further

8 e data demonstrate an effective approach for gene manipulation and provide insights into the epigenet

9 However, advances in gene manipulation and stem-cell therapy suggest cautious

10 Yet single gene manipulations and environmental interventions can s

11 ing to examine the channel activity, and (4) gene manipulations and other methods to determine the un

12 s or subjected to adenoviral vector-mediated gene manipulations and then to glucose-induced IRS-2 exp

13 sequence (UAS) binary system is powerful for gene manipulation, but GAL4 expression is often too broa

14 n organism in which metabolic challenges and gene manipulation could address the enigmatic pathophysi

15 We developed a method that exploits GFP for gene manipulation, Cre recombinase dependent on GFP (CRE

16 Similar to the effects of gene manipulation, declining levels of endogenous BST2 i

17 onclude that current artificial selection or gene manipulation experiments focus on pleiotropy.

18 The elucidation of models with single-gene manipulations has also identified immune mechanisms

19 stems, despite their considerable utility in gene manipulation, have pitfalls in certain scenarios, s

20 ine of three strains used as backgrounds for gene manipulations (i.e., C57, 129/SvJ, and WBB6).

21 racing or cell lineage tracing combined with gene manipulation in a second lineage.

22 aches offer a powerful strategy for targeted gene manipulation in any plant species.

23 c animals are corroborated by in vitro acute gene manipulation in cultured wild type adult mouse vent

24 control, during which the full potential of gene manipulation in insect systems will ultimately be r

25 Increased use of gene manipulation in mice (e.g., targeted or random muta

26 the social defeat phenotype induced by Fosb gene manipulation in MSN subtypes.

27 Gene manipulation in the mouse has discovered multiple c

28 Through the approaches of gene manipulation in the mouse model, a substantial body

29 nal significance of this gene using targeted gene manipulation in the mouse.

30 g its functional significance using targeted gene manipulation in the mouse.

31 In this study, we used conditional gene manipulations in mice and explored the roles of bet

32 ner is not applicable to cell tracing and/or gene manipulations in more than one lineage at a time.

33 Model systems with target gene manipulations involving Fas ligand, Fas, perforin,

34 Embryonic stem (ES) cell-based gene manipulation is an effective method for the generat

35 complicated because the potential outcome of gene manipulation is difficult to predict.

36 Here, by use of biologic, biochemical, and gene manipulation methods in human polymorphonuclear neu

37 s with an interest in studying the effect of gene manipulation on phosphoinositide metabolism in zebr

38 ditions where activation is obtained through gene manipulation or encounters with environmental signa

39 Clonal NSC REST and CoREST gene manipulation paradigms further revealed that CoREST

40 ecent years as a highly efficient RNA-guided gene manipulation platform.

41 ith high-throughput model systems, efficient gene manipulation provides an increasingly powerful tool

42 or behavior may help to parse the effects of gene manipulations relative to strain differences in mut

43 n between Notch and Wnt, we employed a novel gene manipulation strategy in cultured embryonic kidneys

44 his interpretation comes from the results of gene manipulation studies in mice, as well as the sequen

45 Although often demonstrated in artificial gene manipulation studies in model organisms, and some e

46 In vitro gene manipulation studies revealed that FGF1 is sufficie

47 ization of QNS offers a promising target for gene manipulation studies toward the production of novel

48 e used to assess neuronal cultures following gene manipulation such as RNAi, and to study induced plu

49 s, there is a need for an inner ear-specific gene manipulation system for loss- and gain-of-function

50 Continual refinements in gene manipulation technology in mice offer the opportuni

51 There are currently no interventions or gene manipulations that can prevent, stop or reverse the

52 Through gene coexpression and targeted gene manipulations, the malleobactin pathway was success

53 k of high-throughput molecular resources and gene-manipulation tools.

54 ey underscore the advantage of investigating gene manipulation using in vivo functional imaging.

55 by exploiting placental trophoblast-specific gene manipulation using lentiviral vectors, which has be

56 Cre-mediated gene manipulation using transgenic lines that express Cr