ライフサイエンスコーパス: gene mapping

1 a prerequisite for population-based disease gene mapping.

2 rate (FDR) controlling procedure in disease gene mapping.

3 brium has become important in the context of gene mapping.

4 neglected topics, given their importance in gene mapping.

5 a high-throughput SNP genotyping method for gene mapping.

6 e in medical detection, DNA diagnostics, and gene mapping.

7 t constitutes a novel approach to suppressor gene mapping.

8 large-scale association analysis for disease-gene mapping.

9 sociation methods are crucial for successful gene mapping.

10 gnificant practical implications for disease-gene mapping.

11 well to expectations of current methods for gene mapping.

12 lightly different ways, as a methodology for gene mapping.

13 ng loci, and be an important tool in disease gene mapping.

14 complex diseases and strategies for disease gene mapping.

15 cted to provide the best-possible guides for gene mapping.

16 rovide a rapid and robust tool for zebrafish gene mapping, a panel of radiation hybrids (RH) was prod

17 ome, we have also examined the expression of genes mapping adjacent to UBE1.

18 In conclusion, gene mapping, allele sequence data, expression profile a

19 int sequencing, population screening, online gene mapping, allelic discrimination of tumor-associated

20 together with graphical displays of RNAi to gene mappings allow quick intuitive comparison of result

21 le phenotypic or diagnostic endpoints into a gene-mapping analysis.

22 Moreover, these reagents will simplify gene mapping and analyses of genomic fragments in fetal

23 genetic markers that may be most useful for gene mapping and association studies.

24 , comparative sequence analysis, comparative gene mapping and candidate disease gene identification,

25 hese influences is increasingly important as gene mapping and case-control studies are initiated in S

26 ges offered by reciprocal translocations for gene mapping and cloning, T(2;10)67Gso should prove a va

27 d application of molecular marker assays for gene mapping and discovery in field crops and trees.

28 AB-NAM an important tool for high-resolution gene mapping and discovery of novel allelic variation us

29 Integrated maps are useful for gene mapping and establishing the relationship between r

30 The results presented are useful for gene mapping and evolutionary and comparative genomics o

31 ing designs required by association studies, gene mapping and evolutionary biology, the National Canc

32 ing designs required by association studies, gene mapping and evolutionary biology, the National Cent

33 d that they may be most promising for future gene mapping and for extending pedigrees by phenotyping

34 rtant implications for strategies of disease-gene mapping and for understanding human evolutionary hi

35 advantage, fueling significant exchanges of gene mapping and functional information especially betwe

36 enetic background interactions, we integrate gene mapping and gene mRNA expression data in segregatin

37 segments could have a substantial impact on gene mapping and health.

38 s have been due to technological advances in gene mapping and in statistical methods that relate gene

39 molecules opens new possibilities in optical gene mapping and in the fundamental study of DNA-protein

40 vent of sophisticated genomic techniques for gene mapping and microarray analysis has provided opport

41 of the longSAGE retina tags enhanced tag-to-gene mapping and revealed alternatively spliced genes.

42 Gene mapping and sequencing data lead to the generalizat

43 ted to a specific gene and require laborious gene mapping and sequencing.

44 e data is an important task for both disease-gene mapping and studies of human evolution.

45 disequilibrium (LD) is of great interest for gene mapping and the study of population history.

46 Our hybrid resources will allow inexpensive gene mapping and we expect that this technology can be t

47 escribed on the basis of chromosome studies, gene mapping, and DNA sequencing.

48 ow here the mouse Hmx1 genomic sequence, its gene mapping, and its expression pattern in the developi

49 Clinical diagnosis of CORD, disease gene mapping, and mutation identification.

50 to another gene and suggests that additional genes mapping antisense to known genes may exist.

51 Thus, comparative gene mapping appears to be an efficient strategy for ide

52 linkage analysis (LDLA) is a high-resolution gene mapping approach based on sophisticated mixed linea

53 e data show the power of an integrated human gene-mapping approach for heritable molecular phenotypes

54 computational method, CEGMA (Core Eukaryotic Genes Mapping Approach), for building a highly reliable

55 oth for successful implementation of disease-gene mapping approaches and for inferences about human d

56 l power and resolution compared to classical gene-mapping approaches.

57 ng widely recognized as the new currency for gene mapping as increasing numbers are discovered.

58 build a subnetwork of Gc signaling, with 54 genes mapping as nodes, and 6 non-Gc regulated genes inf

59 The algW gene, mapping at 69 min, was isolated on the basis of it

60 egulators are the products of two paralogous genes mapping at positions adjacent to the corresponding

61 mapping of the 7;18 translocation such that genes mapping at the site of the breakpoint can be ident

62 Effective gene mapping based on genetic association data will requ

63 methods offer a powerful approach to disease gene mapping, based on the association between causal mu

64 is is generally the scenario of interest for gene mapping by LD.

65 Software to perform the gene-mapping calculations, "MALDsoft," is freely availab

66 ve alternative technique in statistics-based gene mapping, cancer diagnostics, and forensic applicati

67 sorders are caused by mutations in different genes mapping close together within the genome.

68 NA and protein sequence data, polymorphisms, gene mapping data and genome coordinates, and comparativ

69 The comparative gene mapping data on ECA14 and ECA21 finely align the ch

70 statistics and basic quality assessments for gene-mapping data, accommodating either pedigree or case

71 Using gene mapping, direct genomic sequencing, and extended ha

72 Gene mapping efforts are now focussing on linkage disequ

73 practical implications of these results for gene mapping efforts.

74 a marker for a disease subtype suitable for gene mapping efforts.

75 ding of genetic variation will help to guide gene-mapping efforts.

76 human traits thus far and will guide future gene-mapping efforts.

77 ovel chromosome 21 genes and four paralogous genes mapping elsewhere in the human genome.

78 evaluation, immunologic assays, homozygosity gene mapping, exome sequencing, Sanger sequencing, and f

79 ause its position was estimated from a trait gene mapping experiment, a chromosome segment should be

80 Gene mapping experiments including transfections of UGT1

81 algorithm to define the asthma phenotype in gene mapping family-based studies.

82 The current gene mapping for complex diseases is heavily weighted by

83 These include studies in gene mapping, functional characterization of previously

84 By transracial gene mapping, genetic susceptibility to anti-Jo-1 and ot

85 esource utilization given a set of SNP-based gene-mapping goals.

86 Gene mapping has identified OS mutations within a protei

87 echnological developments in human and mouse gene mapping, has additionally provoked extensive compar

88 A whole brain immediate early gene mapping highlighted the dorsolateral bed nucleus of

89 standardized gene list and a fully traceable gene mapping history for each gene from the original tra

90 Despite the success in gene mapping, however, cloning of complex trait loci or

91 Gene mapping identified a single base pair deletion in m

92 t serve as a leverage tool for complex trait gene mapping if genomes are screened with the appropriat

93 aphids, and the results indicate that target gene mapping in aphids is feasible.

94 In nature, gene mapping in field pedigrees is required to study soc

95 Comparative gene mapping in mammals typically involves identificatio

96 Exome sequencing is a promising tool for gene mapping in Mendelian disorders.

97 s provide a new genomic tool for comparative gene mapping in the cat and related Felidae, and provide

98 reening and should accelerate the process of gene mapping in the future.

99 morphism analysis (SSCP) can be utilized for gene mapping in zebrafish.

100 Cell wall related genes mapping in genomic regions involved into tomato bi

101 Transcription of the acrABDEF genes, mapping in three widely spaced loci, was elevated

102 ry maintenance using ex vivo immediate-early gene mapping, in vivo neuronal recordings and viral-medi

103 By examining differentially expressed genes, mapping information, and genome resequencing, we

104 kage disequilibrium (MALD) is a whole genome gene mapping method that uses LD from extended blocks of

105 ics packages that provide a full spectrum of gene mapping methods, ranging from parametric linkage in

106 the accuracy, by using two population-based gene-mapping methods-likelihood-based linkage-disequilib

107 netic association studies the mainstream for gene mapping of complex human diseases.

108 procortistatin and the mRNA distribution and gene mapping of mouse cortistatin.

109 lected at the molecular level by comparative gene mapping of SSC12 and HSA17.

110 Orthologous gene mappings of Drosophila genes to other organisms are

111 enetic studies, the high-resolution (gene-by-gene) mapping of amplicon boundaries and the quantitativ

112 to improved biolabeling experiments, such as gene mapping on a nanometer scale or multicolor microarr

113 logy, such as muscle cell transplantation or gene mapping, open exciting possibilities for future nov

114 68, with a limited number of CG8486-specific genes mapping outside the hypervariable carbohydrate bio

115 ver risk alleles and complements established gene-mapping paradigms in neuropsychiatric disease.

116 A composite interval gene mapping procedure for complex binary disease traits

117 additionally provoked extensive comparative gene mapping projects for domestic species of several ve

118 y patterns across ethnic groups may increase gene-mapping resolution.

119 These data, together with other available gene mapping results in SLE, are beginning to allow a pr

120 six orders of placental mammals, confirm the gene-mapping results and indicate that the multiple huma

121 Gene mapping shows that exons 1-16 and the P1 promoter s

122 A analyses, construction of genetic maps and gene mapping studies aiming to link phenotype and genoty

123 Disease-gene mapping studies and a simulation study gave differi

124 ch for mapped BAC clones that can be used in gene mapping studies and chromosomal mutation analysis p

125 Gene mapping studies demonstrated that, in contrast to t

126 Gene mapping studies in animal mutants with anaemia due

127 gnificant heritability supports their use in gene mapping studies of AgP susceptibility.

128 Phenotype assessment is a crucial issue in gene mapping studies of asthma.

129 aluable strategy for increasing the power of gene mapping studies of complex diseases.

130 human identification and parentage testing, gene mapping studies, cancer diagnostics, and diagnosis

131 Moreover, they show that, in gene mapping studies, genetic data from both parents and

132 or more major genes and thus be suitable for gene mapping studies, segregation analyses were performe

133 taken in regard to disclosure and consent in gene mapping studies.

134 approach for improving power complex traits gene mapping studies.

135 ar families commonly used in complex disease gene mapping studies.

136 ey are not directly observed in most current gene mapping studies.

137 pring trios are widely collected for disease gene-mapping studies and are being extensively genotyped

138 t genotyping errors lead to loss of power in gene-mapping studies and underestimation of the strength

139 Many gene-mapping studies for healing ability have been perfo

140 t assessment of glucose metabolism, enabling gene-mapping studies in large population samples.

141 Previous gene-mapping studies indicating the existence of two loc

142 These results suggest that future gene-mapping studies may identify pleiotropic genetic va

143 riation in molecular population genetics and gene-mapping studies of diseases with complex inheritanc

144 Gene-mapping studies routinely rely on checking for Mend

145 This is especially true for gene-mapping studies that focus on complex diseases that

146 However, despite converging evidence from gene-mapping studies, aspects of the genetic contributio

147 ype imputation is necessary for facilitating gene-mapping studies, especially with the ever increasin

148 They show potential for gene-mapping studies.

149 genetic markers or functional candidates in gene-mapping studies.

150 is mouse model of childhood cancer, we did a gene mapping study with the SWXJ-9 recombinant inbred st

151 To our knowledge, this is the first gene-mapping study of abnormalities of X-inactivation pa

152 Existing methods for orthologous gene mapping suffer from two general problems: (i) they

153 technologies in combination with traditional gene mapping techniques, such as linkage analysis, can h

154 Our approach unifies two main goals of gene mapping that have generally been treated separately

155 ptimization Strategy (GOST), for orthologous gene mapping through combining sequence similarity and c

156 We identified RIL, a LIM domain gene mapping to 5q31, a region frequently deleted in acu

157 s a candidate prostate cancer aggressiveness gene mapping to 7q32-q33.

158 OVCA1 is a candidate tumor suppressor gene mapping to a highly conserved region on chromosome

159 iated with a maternally expressed, imprinted gene mapping to chromosome 15q11-13.

160 ndidate prostate cancer tumor aggressiveness gene mapping to chromosome 7q32-q33.

161 LIN-1 as a candidate for a tumour suppressor gene mapping to human chromosome 7q31.1.

162 range of applications from microarray-based gene mapping to identification of chromosomal mutations.

163 en described as a single-locus multi-allelic gene mapping to molecular linkage group (MLG) F.

164 es is useful in studies ranging from disease gene mapping to speciation genetics.

165 Xist, a gene mapping to the X-inactivation centre (Xic), is excl

166 Our findings indicate that a gene mapping to this region is mutated in either C57BL/6

167 expression of 122 (61%) and 88 (27%) of the genes mapping to 1p35-36 and all of 11q, respectively, s

168 Two genes mapping to 9p21, p15 and p16, encode inhibitors fo

169 To facilitate the identification of genes mapping to amplified regions, we have used a techn

170 rkers and subsequent evaluation of candidate genes mapping to areas of interest will be increasingly

171 nd frequency of gene amplification affecting genes mapping to ch13q34 in human breast cancer.

172 t that altered transcriptional regulation of genes mapping to chromosome 1 may contribute to disease

173 hit." Alternatively, other tumor suppressor genes mapping to chromosome 10q22-23 could be the actual

174 ing in a haploinsufficiency of RB1 and other genes mapping to chromosome 13, as well as activation of

175 aracterized by significant overexpression of genes mapping to chromosome 1q, and both exhibited a poo

176 impairs gene transcription, particularly at genes mapping to clusters such as HOX and PCDHB.

177 ic regions containing the orthologs of human genes mapping to human chromosome 20q.

178 ster of genes to be flanked predominantly by genes mapping to human chromosomes 7 and 19.

179 is analysis revealed 44 highly overexpressed genes mapping to localized amplicons on chromosome 13, g

180 On the other hand, genes mapping to loci outside of the major histocompatib

181 t been analyzed in detail; to date, only VZV genes mapping to open reading frames (ORFs) 4, 21, 29, 6

182 hnologs are significantly overrepresented in genes mapping to pathogenic CNVs, irrespective of how CN

183 26 genes mapping to the 1q arm show highly significant (P</

184 er of candidate genes was reduced, and a few genes mapping to the BBS3 interval emerged as the best c

185 ohn's disease (CD), showed associations with genes mapping to the cytokine gene cluster on 5q31.

186 Twelve genes mapping to the deleted region were reliably identi

187 has been entirely sequenced and many of the genes mapping to the deletion interval have been studied

188 rs at the same rate as that observed between genes mapping to the distal portion of the circular chro

189 -mb region that included RUNX1, miR-802, and genes mapping to the Down syndrome critical region.

190 rt-range linkage with five orthologous human genes mapping to the Major Histocompatibility Complex (M

191 o H-Y are controlled by immune response (Ir) genes mapping to the MHC.

192 Transcripts for genes mapping to the p38 mitogen-activated protein kinas

193 Additionally, the expression of genes mapping to the Saltol region of chromosome 1 were

194 In addition, several genes mapping to this region show imprinted expression,

195 the positional cloning of candidate disease genes mapping to Xp22.1 and is therefore of value for th

196 ohnologs between these gene sets and control genes, mapping to CNVs not known to be disease associate

197 Gene expression profiling and gene mapping using 500K single-nucleotide polymorphism (

198 a collection of families for fine-structure gene mapping using allelic association.

199 method for fine-scale linkage-disequilibrium gene mapping using high-density marker maps.

200 r is concerned with efficient strategies for gene mapping using pedigrees containing small numbers of

201 Immediate early gene mapping using zif268 in situ hybridization revealed

202 For disease gene mapping, using both simulated and real data sets on

203 Gene mapping was performed utilizing a polymorphism iden

204 ds mainly rely on sequence-based orthologous gene mapping, which often leads to suboptimal mapping re

205 Finally, gene mapping with a (C57BL/6J x SPRET/Ei)F1 x SPRET/Ei m

206 logistic regression in case-control disease gene mapping with a large number of SNPs (single nucleot

207 eexamine the role of random effect models in gene mapping with inbred strains.

208 Gene mapping with microsatellite markers demonstrates th

209 Gene mapping with recombinant inbred BXD strains reveale

210 pport the hypothesis that a tumor suppressor gene mapping within 11q23.3 is commonly inactivated duri

211 Overexpression of CKS1B, a gene mapping within a minimally amplified region between

212 e microrchidia CW-type zinc finger 2 (MORC2) gene mapping within the linkage region.

213 The AF-6 gene, mapping within RMD-1, revealed no mutations in a s

214 Investigators targeting 129/Sv genes mapping within chromosomal regions reported herein

215 Genes mapping within rare CNVs in TS showed significant

216 implicated in copy number pathogenicity: (i) genes mapping within rare disease-associated CNVs, (ii)

217 Eleven of the genes mapping within the SMS common deletion region have

218 Key genes mapping within these deleted regions include PTEN,

219 Key amplified genes mapping within these regions include SKP2, FOXA1,