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1 xnIP promoter, controlling expression of its gene product.
2 tions in at least 1 PI3K pathway gene and/or gene product.
3 ementation lines when attributing roles to a gene product.
4 terwoven into networks, rather than a single gene product.
5 differential expression of the small Ad E1B gene product.
6 ferentially modified proteoforms of the same gene product.
7 rily conserved Cys residue for an Arg in the gene product.
8 thways via a single evolutionarily conserved gene product.
9 omplexity otherwise inaccessible to a single gene product.
10 ange in the redox state of the corresponding gene product.
11 erk1/2) and is restrained by a JAK-dependent gene product.
12 ombicola, and the functional activity of its gene product.
13 many Archaea form homohexamers from a single gene product.
14 n in tsv causes premature termination of the gene product.
15 molecular identification of the Sm1 and Sm2 gene products.
16 of the predicted protein interactions of the gene products.
17 ratus have been identified, most as deafness gene products.
18 d increased expression of many of these same gene products.
19 lipid homeostasis in concert with their host gene products.
20 ed in subfunctionalization of the respective gene products.
21 andards for accurate representation of these gene products.
22 tification of 14,213 phosphosites from 4,499 gene products.
23 od of the Human Papillomavirus (HPV) encoded gene products.
24 rally regulate late expression of structural gene products.
25 up-regulate the expression of Nrf2-dependent gene products.
26 contribute to the heterogeneity observed in gene products.
27 nt form that does not actively express HIV-1 gene products.
28 ing behind the more abundant HLA-A and HLA-B gene products.
29 ing RNA had no effect on expression of these gene products.
30 ure models are available for the majority of gene products.
31 oolkit will prove useful for the analysis of gene products.
32 o a gain or loss of conserved domains in the gene products.
33 HMGB1) and the hypoxia upregulated-1 (HYOU1) gene products.
34 used resource to describe the attributes for gene products.
35 of MERS-CoV and human interferon-stimulated gene product 15 (hISG15) was probed with isothermal calo
37 uitin (Ub) and Ub-like interferon-stimulated gene product 15 (ISG15) to stabilize, or activate, a var
38 teins by ubiquitin and interferon-stimulated gene product 15 (ISG15), subsequently facilitating downr
40 ure of the bacteriophage T4 portal assembly, gene product 20 (gp20), determined by cryo-electron micr
41 s mutations that disrupt function of the MMR gene product: 31 in MLH1 (61%), 11 in MSH2 (21%), 3 in M
43 m (un)folding intermediate state of T4 phage gene product 45 (gp45, also known as DNA polymerase proc
44 ervation was stained with 2 markers: protein gene product 9.5 (PGP 9.5), a general neuronal marker, a
45 was used with antibodies specific to protein gene product 9.5 (PGP9.5) and, for the first time in hum
46 zation showed increased TUBB3(+) and protein gene product 9.5(+) Merkel cells during in vivo repair,
47 ation of the maize insect resistance1 (mir1) gene product, a cysteine (Cys) proteinase that is a key
52 a functional core proteome consisting of 356 gene products, accounting for 44% of the Escherichia col
53 roject integrates data about the function of gene products across a diverse range of organisms, allow
60 a multienzyme complex that includes the mcrC gene product, an Fe-protein homolog, an iron-sulfur flav
61 is the annotation, an association between a gene product and a term from one of the three ontologies
63 lack of a strong, dominant function for each gene product and the ability of many viruses to interfer
66 e single csoS2 gene yields expression of two gene products and both display an apparent molecular wei
67 -binding adaptor shared by APAF-1, certain R gene products and CED-4) and NACHT (named for NAIP, CIIA
68 typic networks were associated with distinct gene products and clinical syndromes (i.e., the schizoph
69 eptide generation at the level of individual gene products and create a predictive algorithm for dise
70 anscriptome, revealing previously undetected gene products and isoform-specific protein expression.
71 (citations, nomenclature, genomic location, gene products and their attributes, phenotypes, sequence
72 part of the currently undruggable genes and gene products and to generate entirely new therapeutic p
73 adipocytes produced striking increases in P2 gene-products and dramatic falls in P1-transcribed mRNA,
75 representing essentially all canonical human gene products, and we exemplify the utility of these dat
76 olecular screens reveal functionally related gene products; and advanced proteomic methods can determ
77 as well as an increase in both the number of gene product annotations and their granularity, thus imp
79 A2*05 gene is present in abundance, and its gene products are characterized by low cell-surface expr
86 iated with mutations in NPC1 and NPC2, whose gene products are key players in the endosomal/lysosomal
89 f HSCR genes and haploinsufficiency of their gene products are the primary pathogenic mechanisms for
91 expression and correct trafficking of target gene products as assessed by immunofluorescence assays a
93 belliferone directly and selectively blocked gene products associated with the pro-catabolic metaboli
96 required the breast and ovarian susceptible gene product BRCA1, highlighting important roles of the
97 ls are not controlled by Mbl or the Laccase2 gene product but rather by multiple hnRNP (heterogeneous
100 logy in mouse models and that the HTT exon 1 gene product can self-assemble into amyloid structures.
101 and biochemical properties of CAPN14 and its gene product CAPN14, and its emerging role in patients w
102 4, rs3740393) were located near AS3MT, whose gene product catalyzes methylation of iAs to MMA and DMA
104 ings identify that the asthma susceptibility gene product CDHR3 mediates RV-C entry into host cells,
106 tenance in wild-type mice, PKCiota/lambda, a gene-product closely related to PKMzeta, persistently in
107 Interestingly, transient expression of SPFMV gene products coagroinfiltrated with a reporter gene in
108 ty of Leptospira interrogans strain Lai colA gene product (ColA) to hydrolyze different collagenic su
110 TSV genome revealed a potential three-domain gene product containing an N-terminal leucine-rich repea
111 n order to infer the properties of genes and gene products containing little or no experimental annot
113 vel synaptogenic mechanism in which a single gene product coordinates the nuclear transcription and p
115 , implying that the THIAMIN REQUIRING2 (TH2) gene product could be a dedicated ThMP phosphatase.
116 nonical defense pathways and how herpesvirus gene products counter them, highlighting the contributio
117 oaches are required to study the function of gene products critical for growth and erythrocyte invasi
118 o control the copies and residence time of a gene product delivered in host human cells but also sele
119 espite acting in a common pathway, each PCLD gene product demonstrated distinct effects on polycystin
120 r burden of NsM generates novel epitopes and gene products, detected by the immune system as foreign.
122 In Saccharomyces cerevisiae, five related gene products (Dnf1, Dnf2, Dnf3, Drs2, and Neo1) are imp
123 the peptidase domain of the Synpcc7942_1133 gene product (dubbed PteB for peptidase transporter esse
124 t that potential exposure to DsRed2 and tTAV gene products (e.g. mRNA and encoded proteins) would hav
125 BE3A gene and aberrant overexpression of the gene product E6AP protein is a common cause of autism sp
126 ing of avirulence genes PWT3 and PWT4, whose gene products elicit defense in wheat cultivars containi
127 petence regulation and stress tolerance by a gene product encoded within the comX gene that appears u
128 it the longstanding concept that some of the gene products encoded by ERVs and other endogenous viral
129 rotein triggering each of the two resistance gene products; epidemiology of RB isolates is discussed
135 ystematically screened all human phosphatase gene products for a regulatory role in the SMN complex.
136 ry mechanism ensures optimal output of these gene products for proper physiological function of the a
138 we examined the relative roles of two viral gene products for the ability to promote loss of the ant
139 und that vesicles containing the PKHD1/Pkhd1 gene product, FPC, also contain the NEDD4 ubiquitin liga
140 the FMR1 gene leading to the absence of its gene product, fragile X mental retardation protein (FMRP
143 cadian pacemaker gene frequency (frq), whose gene product, FRQ, as a part of the FRQ-FRH complex (FFC
144 nk the presence of an SNP to altered in vivo gene product function and hence contribute to disease ri
146 ordinated interactions between diverse human gene products functioning within various pathways underl
150 an 70 distinct loci and more than 50 mutated gene products have been identified in patients with here
152 ressed proteins, including podocyte-specific gene products, identified in an unbiased tandem mass spe
160 nt with this finding, examination of Slc52a3 gene products in adult tissues revealed expression in th
162 GFP enables localization and quantitation of gene products in otherwise unmanipulated live cells or o
163 nt differences exist in the role of specific gene products in regulating analogous steps in the gener
166 ein resulting from fusion of MIA2 and cTAGE5 gene products, in the export of pre-chylomicrons and pre
168 complex inheritance and potentially complex gene product interactions during development, contributi
169 bined 651 gene expression datasets with 1.4M gene product interactions to predict the inclusion of 40
170 erms of biomedical concepts (e.g., genes and gene products, interactions and processes) rather than f
173 synthesis using a high throughput screen for gene products involved in capsular alpha-glucan producti
174 t: 1) OmpR regulates mostly membrane-located gene products involved in diverse fundamental biological
175 ges aiming at the unbiased identification of gene products involved in Nlrp3 inflammasome activation.
177 ocus TNIP1, also referred to as ABIN1, whose gene product is a negative regulator of various inflamma
178 ures, non-optimal codon use, and those whose gene product is cotranslationally translocated into the
179 etion analysis indicated that only the cel3B gene product is essential for efficient cellodextrin uti
180 sarcoma-associated herpesvirus (KSHV) ORF57 gene product is essential for lytic KSHV replication and
182 egulates plant architecture whereas the Ant1 gene product is involved in anthocyanin biosynthesis.
183 nding how expression of this essential viral gene product is regulated may identify new strategies fo
184 are needed to determine, for example, which gene product is responsible for catalyzing each step in
185 hermore, the results suggest that sharing of gene products is limited, and thus there is incomplete b
186 well established that neurofibromin, the NF1 gene product, is an antioncogene that down-regulates the
189 ribe the manual annotation of a selection of gene products known to be associated with autism and/or
191 activity classifications based on changes in gene product level are mechanistically uninformative, we
193 a SCZ genome-wide association studies and in gene products localized to mitochondria and cytoplasm.
195 nce that these modules and their constituent gene products may play central roles in metabolic inflam
201 munotoxin sensitivity, indicating that these gene products normally contribute to inefficiencies in t
203 t RNA polymerase from the Hepatitis C Virus (gene product NS5B) is a validated drug target because of
204 hin nuclear-encoded genes with mitochondrial gene products (odds ratio, 1.075; 95% CI, 1.018-1.135; P
206 rt that mutant huntingtin (Htt), a causative gene product of Huntington's diseases (HD) selectively i
207 independent growth, which is mediated by the gene product of its target gene HMGA1, encoding a multip
209 mox organism Kuenenia stuttgartiensis as the gene product of kustc0694 and determined some of its cat
210 Polyoma small T antigen (PyST), an early gene product of the polyoma virus, has been shown to cau
214 has been growing interest in the homodimeric gene products of CISD1 (mitoNEET) and CISD2 (NAF-1), the
215 of PSAT by annotating the predicted peptide gene products of Herbaspirillum sp. strain RV1423, impor
221 Individual binding sites of select KSHV gene products on PAN RNA were also identified in in vitr
223 s were cholinergic, colocalized with protein gene product (PGP)9.5, the vesicular ACh transporter, an
224 e R (PKR), a classical interferon-stimulated gene product, phosphorylates the eukaryotic translation
225 s associated with a combined deficiency of 2 genes products, PI3-kinase p110delta and SKAP, both of w
226 ated the dispensability of the canonical ie3 gene product pIE611 for viral replication and delineated
229 l dominant polycystic kidney disease (ADPKD) gene products polycystin-1 and polycystin-2 localize to
230 teome-based assay revealed that the NAALADL1 gene product possesses previously unrecognized aminopept
234 erent data types including sequences, genes, gene products, proteins, protein domains, protein famili
235 ude nucleotide and protein sequences, genes, gene products, proteins, protein domains, protein famili
238 nd downstream phosphorylation of the AD risk gene product Pyk2, and of NR2B Glu receptors in brain sl
239 sis with cellulosic substrates, seven of the gene products (Ra0185, Ra0259, Ra0325, Ra0903, Ra1831, R
241 of mutant plants it is known that the Ert-m gene product regulates plant architecture whereas the An
242 izophrenia, alterations in the expression of gene products regulating these properties could disrupt
244 f herpes simplex virus 1 (HSV-1) is an alpha gene product required for viral replication at low multi
247 Transposon mutagenesis identified several gene products required for symplasmata formation, includ
248 ered with optical reporters and tumouricidal gene products retain the capacity to differentiate and i
249 n together, our data imply that the NAALADL1 gene product's primary physiological function is associa
250 control of another unknown RpoS-independent gene product(s) associated with borrelial replication.
251 of lytic transcripts, and a late lytic KSHV gene product(s) targets IFI16 for degradation during lyt
253 of intense miRNA innovation and that mature gene products show a very different tempo and mode of se
256 oisomerase-induced DNA breaks and the RecBCD gene products, suggesting a new co-antibacterial strateg
258 structure and molecular function of ClbS, a gene product that confers resistance to colibactin toxic
259 ndividual baboons, the identity of the viral gene product that is the major target of cellular immune
261 significantly reduces expression of over 600 gene products that are targets of the DREAM complex, whi
264 12 previously known Saccharomyces cerevisiae gene products that function in tRNA processing, turnover
265 t feature of HCMV is the wide range of viral gene products that it encodes which function to modulate
266 udies in schizophrenia reveal alterations in gene products that regulate the release and extracellula
269 ssociated with an up-regulation of the ALOX5 gene product, the 5Lipoxygenase (5LO), herein we investi
271 Despite biochemical studies on individual gene products, the composition and cofactor requirement
273 Although these screens affect thousands of gene products, the typical readout is based on low compl
275 asic activation of a traditionally antiviral gene product through an EGFR- and integrin-dependent pat
276 that tolerance can be modulated by microRNA gene products through the control of opposing activities
277 ir targets impart rhythmic functions to many gene products through transcriptional, posttranscription
279 e analysis of the contribution of microbiome gene products to community assembly, host physiology, an
280 tein-protein interactions among at least six gene products to form a metabolic core, around which the
281 ks to implement stochastic switches that map gene products to phenotypes, and investigate the impact
282 our understanding of how drugs interact with gene products to produce physiological responses (phenot
283 elopment is passed from exclusively maternal gene products to those encoded by the embryonic genome i
286 ry function is to regulate the expression of gene products via hybridization to mRNA transcripts, res
287 , we report that human herpesvirus 8 (HHV-8) gene product viral interferon regulatory factor 1 (vIRF-
288 rary for deficiency in acetylation, the yvoF gene product was identified to be the acetyltransferase.
290 sease and establish that the Wiskott-Aldrich gene product (WASP) serves an essential role in T regula
291 ling of all annotated and predicted secreted gene products, we find that NF-kappaB activity is requir
294 racted attention about a decade ago when CMV gene products were found in glioma tissue but not in nor
296 t assays further verified that the virulence gene products were produced and that the T3SS effector E
297 The clusters correspond to small sets of gene products, which can be processed quickly to give ca
298 st time that hydin, a hydrocephalus-inducing gene product whose mutation impairs ciliary motility, an
299 ghly conserved ortholog of the DrosophilaEcd gene product whose mutations impair the synthesis of Ecd
300 probably a result of heterotetramers of Kir2 gene products, with this regulating resting potentials a
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