ライフサイエンスコーパス: gene recombination

1 lls, of forming antigen receptors by somatic gene recombination.

2 eus and locus contraction in preparation for gene recombination.

3 tosis during immunoglobulin (Ig) light chain gene recombination.

4 te commitment and immunoglobulin heavy-chain gene recombination.

5 -deficient mice were generated by homologous gene recombination.

6 provides feedback to terminate further V(H) gene recombination.

7 constraints of accessibility to control V(H) gene recombination.

8 but through the control of antigen receptor gene recombination.

9 le, enabling temporal and spatial control of gene recombination.

10 thymus, after TCR-beta but before TCR-alpha gene recombination.

11 teins important in homology-based chicken Ab gene recombinations.

12 izontal DNA transfer and assortative (entire gene) recombination.

13 protein feeds back to terminate further V(H) gene recombination, a phenomenon also referred to as all

14 TCR-beta gene recombination and allelic exclusion were normal in

15 apid adaptation to novel niches by promoting gene recombination and duplication followed by functiona

16 ble lipids into cultured human cells enables gene recombination and genome editing with efficiencies

17 es a molecular basis for chromatin-dependent gene recombination and presents a single protein domain

18 n, preventing down-regulation of light chain gene recombination and promoting secondary light chain g

19 nts in gene therapy by initiating homologous gene recombination and repair.

20 status is inherently and inversely linked to gene recombination and that the outcomes of gene recombi

21 of Ku70 was compatible with T cell receptor gene recombination and the development of mature CD4+CD8

22 n is critical for immunoglobulin light chain gene recombination and to prevent malignant transformati

23 growth, transient activation of the WAP-Cre gene, recombination, and constitutive expression of LacZ

24 Internal gene recombination appears to occur among them.

25 Significant gene recombination ( approximately 80%) occurred in the

26 ifferentiation, cell cycle fluctuations, and gene recombination are coincident during normal T cell d

27 definitive process of T cell receptor (TCR) gene recombination, are presently emerging.

28 The highly restricted timing of V to J gene recombination at the pre-B-cell stage is under the

29 which carry CD19(Cre) that initiates floxed gene recombination at the pro-B-cell stage.

30 Immunoglobulin gene recombination can result in the assembly of self-re

31 sition, a survival program is initiated, TCR gene recombination ceases, cells migrate into a new thym

32 In yeast genes, recombination (conversion) is polarized, being hi

33 ion and caudal portions of the tongue, where gene recombination did not occur until E14.5.

34 High fidelity in vitro gene recombination ("DNA shuffling") coupled with sequen

35 Allele KIR3DL1*009 resulted from a gene recombination event between the inhibitory receptor

36 Together, our data suggest that Ig gene recombination events can generate B cells with auto

37 ajor leaps in protein function occur through gene recombination events that connect two or more prote

38 lta and that might function to regulate Tcrd gene recombination events.

39 ackgrounds suggests that assortative (entire gene) recombination has also contributed to strain diver

40 We propose that the outcome of gene recombination (i.e., TCR expression) may not influe

41 s manipulated to control gene expression and gene recombination in developing thymocytes.

42 Using cell-specific inducible gene recombination in mice we found that, in the postnat

43 nslocation is the most frequent illegitimate gene recombination in paediatric cancer, occurring in ap

44 defect preferentially affects immune system gene recombination in T cells rather than B cells.

45 polymorphism to analyze TCR-alpha and -beta gene recombination in thymically derived gamma delta cel

46 e data indicate a direct role for ATM in TCR gene recombination in vivo that is critical for surface

47 tional protein delivery into mouse brain for gene recombination in vivo.

48 to establish the configuration within which gene recombination initiates.

49 We found that TCR-beta gene recombination is a frequent occurrence in thymic ga

50 racterized mice in which Phox2b-Cre mediated gene recombination labeled neurons with tdTomato.

51 that ablation of Fmrp in aNSCs by inducible gene recombination leads to reduced hippocampal neurogen

52 Because NK cells lack gene-recombination machinery and are thought to be relat

53 development is blocked and ongoing antibody gene recombination occurs, which often alters antibody s

54 Random pairwise gene recombination of two positive variants led to a fur

55 variable [V], diversity [D], and joining [J] genes) recombination of their antigen receptor loci to c

56 gests anomalies of evolution such as partial gene recombination or functional constraints.

57 acquired through errors in DNA replication, gene recombination, or extrinsically imposed damage, are

58 ted mutations, although the possibility that gene recombination plays a role cannot be eliminated.

59 gene recombination and that the outcomes of gene recombination regulate developmental progression.

60 disrupted targeting at the tongue tip, where gene recombination removed bdnf by embryonic day 13.5 (E

61 Gene recombination-specific enzymes were assessed by PCR

62 s with a lymphoid past were identified in Ig gene recombination substrate reporter mice treated with

63 s of murine immunoglobulin heavy-chain (IgH) gene recombination take place within a chromosomal domai

64 To develop a quantitative assay for pilin gene recombination that is independent of phase variatio

65 While the RecA protein is required for pilin gene recombination, the factors which maintain the silen

66 he nucleus and retain its activity to induce gene recombination, this in vitro experiment better exem

67 Within genes, recombination tracts are more likely to terminate

68 Here we report that adipocyte-specific Lpin1 gene recombination unexpectedly resulted in expression o

69 polypurine site situated between the two TK genes, recombination was observed at frequencies in the