ライフサイエンスコーパス: gene transcription

1 1 contains an AD required for Rap1-dependent gene transcription.

2 t blocks repressor complexes to enable viral gene transcription.

3 and conserved mechanism in the regulation of gene transcription.

4 promoter H3K4me3 histone marks and increased gene transcription.

5 CSCs by epigenetically activating Wnt target gene transcription.

6 of cellular signaling, protein folding, and gene transcription.

7 of p53R172H can be a surrogate marker of p53 gene transcription.

8 via two tandem BDs, BD1 and BD2, to regulate gene transcription.

9 cell growth after acute stress by regulating gene transcription.

10 rhythmicities by repressing frequency (frq) gene transcription.

11 hibit increased levels of sigma(F) -directed gene transcription.

12 , plays important roles in the regulation of gene transcription.

13 actor of YAP that enhances YAP/TEAD-mediated gene transcription.

14 veals spatial features that causally control gene transcription.

15 IPMK is predominantly nuclear and regulates gene transcription.

16 ecific interplay between DNA methylation and gene transcription.

17 matin remodeling in the control of TGF-beta1 gene transcription.

18 c DNA demethylation to activate pluripotency gene transcription.

19 K4 methylation, thereby promoting Wnt target gene transcription.

20 lymerase II for the initiation of eukaryotic gene transcription.

21 nvasion could be via the regulation of MMP-2 gene transcription.

22 , this effect does not occur at the level of gene transcription.

23 of raising 25(OH)D have disparate effects on gene transcription.

24 uired for efficient CREB phosphorylation and gene transcription.

25 e translocations from DSBs introduced during gene transcription.

26 gulator of major histocompatibility class II gene transcription.

27 ound to interact with chromatin and modulate gene transcription.

28 ore stretching, clarifying how forces affect gene transcription.

29 on factor EB, a known activator of lysosomal gene transcription.

30 ligand (PDF) signaling or rhythmic receptor gene transcription.

31 TAT3 inhibition-mediated suppression of Pomc gene transcription.

32 wn as DNA motifs) are critical activities in gene transcription.

33 the development of inhibitors that modulate gene transcription.

34 romoter region has the potential to regulate gene transcription.

35 om binding to the chromatin, thus inhibiting gene transcription.

36 epigenetic mechanism that regulates nuclear gene transcription.

37 gating postreplicative intermediate and late gene transcription.

38 its paralog p300 to activate CREB-dependent gene transcription.

39 chromatin, thereby attenuating Notch target gene transcription.

40 h NK cell priming at the level of glycolytic gene transcription.

41 s recruiting NF-kappaB and promoting related gene transcription.

42 dehydrogenase 1A1 (ALDH1A1), stimulating its gene transcription.

43 plays a critical role in regulating metazoan gene transcription.

44 the Ash2l complex associated with increased gene transcription.

45 expression and switching on of hematopoietic gene transcription.

46 s a mechanism for precise regulation of BCL2 gene transcription.

47 -ROR response element (RORE) to stimulate AR gene transcription.

48 II is required for silencing of subtelomeric gene transcription.

49 roles of these proteins in intravirion early gene transcription.

50 d in the regulation of DNA repair as well as gene transcription.

51 quent degradation, thus activating Hh target gene transcription.

52 te-dependent manner and can alter the global gene transcription.

53 d histones, linking chromatin recognition to gene transcription.

54 em, feature extensively in the regulation of gene transcription.

55 r body protein involved in the regulation of gene transcription.

56 rogen-responsive elements (EREs) to regulate gene transcription.

57 mechanism by which insulin regulates albumin gene transcription.

58 c receptor but also directly participates in gene transcription.

59 to a mode of regulation other than increased gene transcription.

60 ha and ERbeta, which differentially regulate gene transcription.

61 lating numerous molecular processes, such as gene transcription.

62 ory elements such as enhancers to facilitate gene transcription.

63 tif in SREBP2-mediated activation of C-ACSL1 gene transcription.

64 in lineage-specific enhancer activation and gene transcription.

65 ture and dynamics of chromatin fibers during gene transcription.

66 amic pattern of NPR1 accumulation and target gene transcription.

67 Myf5 occurs without significant induction of gene transcription.

68 histone H3 acetylation and activation of MYC gene transcription.

69 nteract with gene promoter regions to modify gene transcription.

70 is known about the impact of hypercapnia on gene transcription.

71 w the number of repeats of the STR regulates gene transcription.

72 chanism for enhancing the amplitude of clock gene transcription.

73 ing of Cav1.2 channels to activity-dependent gene transcription.

74 tor that functions to moderate developmental gene transcription.

75 tor-kappaB (NF-kappaB)-mediated inflammatory gene transcription.

76 inatal LPD on both Npy1r DNA-methylation and gene transcription.

77 nvironmental exposures and events related to gene transcription.

78 tin structure and plays an important role in gene transcription.

79 , but unlike SC-CA1 synapses, requires rapid gene transcription.

80 protein in molecular complexes that regulate gene transcription.

81 edback loop that inhibits sigma(F) -directed gene transcription.

82 romoters of muscle genes, without activating gene transcription.

83 bition altered cancer signaling pathways and gene transcription.

84 ronwide influences through the regulation of gene transcription.

85 iated regulation of membrane trafficking and gene transcription.

86 rs" and play a key role in the regulation of gene transcription.

87 conformation dictates faithful regulation of gene transcription.

88 protein-protein interaction to enable viral gene transcription.

89 Lys-12 on histone H4, causing repression of gene transcription.

90 uced breast cancer resistance protein (BCRP) gene transcription.

91 ty via modulation of synaptic plasticity and gene transcription.

92 ression and rapid downregulation of cellular gene transcription.

93 binds to enhancer-like regions and increases gene transcription.

94 -chaperones play a direct role in modulating gene transcription.

95 synthesis as well as c-di-GMP-induced stalk gene transcription.

96 chromosome translocations that arise during gene transcription.

97 we used extensive RNA sequence data to track gene transcription across the life cycle of D. viviparus

98 on of STAT3-DNA binding, nuclear export, and gene transcription all prevented LTD induction.

99 and aggregation in the cytosol by adjusting gene transcription and a number of post-transcriptional

100 nism underlying the disruption of prefrontal gene transcription and behavioral functions in subjects

101 r-associated H3K4 methylation, inhibition of gene transcription and blockade of erythroid differentia

102 s physiological cues play important roles in gene transcription and cancer.

103 monstrate our procedure on several models of gene transcription and cell signalling, and show that in

104 copy episomes with complex patterns of viral gene transcription and chromatin structure.

105 l enzyme that plays a number of key roles in gene transcription and DNA repair.

106 V assembles an "all-in-one" factory for both gene transcription and DNA replication.

107 connects chromatin remodeling complexes into gene transcription and gene activity.

108 g is closely related to the dynamic range of gene transcription and generally related to DNA sequence

109 on-homologous end-joining in protecting both gene transcription and genome stability.DNA double-stran

110 all the transcription factors necessary for gene transcription and hypertrophy.

111 ificantly inhibits over 60% of TPA-inducible gene transcription and impairs cell proliferation.

112 we found that sunitinib can stimulate vegfc gene transcription and increase VEGFC mRNA half-life.

113 s a major epigenetic regulatory mechanism of gene transcription and is associated with multiple disea

114 ence suggests that ZNF804A is a regulator of gene transcription and is present in nuclear and extranu

115 regions of genes is negatively regulated by gene transcription and may be modified by early-life exp

116 in-folding environment through reprogramming gene transcription and mRNA translation.

117 ve of vitamin A, exhibits diverse effects on gene transcription and non-genomic regulatory pathways.

118 tors (TKIs) by concurrently stimulating EGFR gene transcription and protein dephosphorylation.

119 This effect increased endothelial gene transcription and protein production of NF-kappaB-r

120 In addition, auxin-induced gene transcription and specifically SAUR proteins are cr

121 3 promoter occurs at an early stage prior to gene transcription and that recruitment of transcription

122 able to suppress major immediate early (IE) gene transcription and the generation of infectious viri

123 The effect of PDF on clock gene transcription and the known role of PDF in enhancin

124 lly caused by the stochastic burst effect in gene transcription and the technical failure of RNA tran

125 ecular rhythms via control over the phase of gene transcription and this timing mechanism resides in

126 s) are a family of novel genes that regulate gene transcription and translation.

127 ters, resulting in suppression of SMC marker gene transcription and, consequently, in inhibition of T

128 lts demonstrate a key role for HDAC1 in PU.1 gene transcription and, more importantly, uncover a nove

129 gest a divergence between mRNA (for example, gene transcription) and protein (for example, RNA transl

130 Elk1 binding alters ITGB6 promoter activity, gene transcription, and alphavbeta6 integrin expression.

131 nscription factors are pivotal regulators of gene transcription, and many diseases are associated wit

132 n genome and have been suggested to suppress gene transcription, and much attention has therefore foc

133 es chromatin accessibility, enhances histone gene transcription, and promotes HLB formation.

134 l processes, such as cellular proliferation, gene transcription, and tumorigenesis, all of which are

135 Some epigenetic changes to DNA that affect gene transcription are at least partially reversible (i.

136 he DNA sequence, the epigenetics, as well as gene transcription are profoundly shaped by serine/threo

137 her than suppressing activators of flagellar gene transcription as in Vibrio and Pseudomonas species.

138 r regions of Snail2 and Twist1 and repressed gene transcription, as determined by EMSA and luciferase

139 ocess involving NF-kappaB signaling and IL1B gene transcription, as well as assembly of the NLRP3 inf

140 hepatosteatosis and major changes in hepatic gene transcription associated with modulation of H3K27Ac

141 In bacteria, the activation of gene transcription at many promoters is simple and only

142 on is mediated exclusively via regulation of gene transcription at the nuclear level.

143 ro, 3-copies of the MSR1 element can repress gene transcription by 50 to 115-fold; (3) the higher-exp

144 Simultaneously, fumarate increases ferritin gene transcription by activating the NRF2 (nuclear facto

145 y protein produced in the very late phase of gene transcription by Autographa californica multiple nu

146 Intranuclear uPA modulates gene transcription by binding to a subset of transcripti

147 n factors (TFs) regulate complex programs of gene transcription by binding to short DNA sequence moti

148 analysis further shows that FACT facilitates gene transcription by destabilizing the tetranucleosomal

149 ecific transcription factors (GSTFs) control gene transcription by DNA binding and specific protein c

150 show a previously unrecognized regulation of gene transcription by GPCR-cAMP signaling through augmen

151 H4K16 acetylation (H4K16Ac) activates gene transcription by influencing both chromatin structu

152 ns results in modulation of estrogen-induced gene transcription by preventing Estrogen Receptor chrom

153 uclear localization, DNA binding, and target gene transcription by reducing AKT-dependent FOXO1 phosp

154 Initiation of gene transcription by RNA polymerase (Pol) III requires

155 s, which suggest that HiNmlR enhances target gene transcription by twisting of operator DNA sequences

156 entify Klf5 as an activator of Dmp1 and Dspp gene transcriptions by different mechanisms and demonstr

157 Gene transcription can be activated by decreasing the du

158 that metabolic and epigenetic regulation of gene transcription can influence MPhi plasticity in woun

159 without emodin, and the effects of emodin on gene transcription, cell signaling pathways, and histone

160 live cells by quantitative imaging of actin gene transcription, combined with molecular genetics, st

161 Most of what we know about gene transcription comes from the view of cells as molec

162 Class II gene transcription commences with the assembly of the Pr

163 PH I) is an essential component of the early gene transcription complex.

164 ssociated with repression of Foxo1-dependent gene transcription, concomitant with reduced Foxo1 expre

165 lly carcinogenic mechanisms such as altering gene transcription, controlling stem cell differentiatio

166 moter, whereas the upregulation of TGF-beta1 gene transcription correlates with reduced occupancy of

167 e embryonic stem cells that endogenous Dnmt1 gene transcription could be up- or downregulated in a tu

168 ccumulation occurs because of an increase in gene transcription coupled with impaired proteasomal deg

169 architecture, linking functional variants to gene transcription, demonstrate the effects of domestica

170 gondii infection blocks IFN-gamma-dependent gene transcription, despite the downstream transcription

171 modeler involved in epigenetic regulation of gene transcription, DNA repair, and cell cycle progressi

172 tion process implicated in the regulation of gene transcription, DNA repair, and cell cycle.

173 We also found modifications in gene transcription, dopamine and serotonin contents, and

174 in-level and loop-based organization of tRNA gene transcription during cellular differentiation.

175 ith TALE and HOX proteins to regulate target gene transcription during development.

176 mily of transcription factors (Fox) controls gene transcription during key processes such as regulati

177 anding of the mechanisms that regulate viral gene transcription during latency.

178 nhancers interferes with and attenuates host gene transcription during productive elongation.

179 hat has previously been shown to promote var gene transcription during the intraerythrocytic cycle in

180 ZBTB transcription factors orchestrate gene transcription during tissue development.

181 structure directly resulted in up-regulated gene transcription, especially M1 gene expression.

182 ero gain-of-function of the psychiatric risk gene transcription factor 4 (TCF4) severely disrupts the

183 ms are abolished by disrupting the key clock gene transcription factor Bmal1.

184 ignificantly with those bound by the S-phase gene transcription factor E2F1.

185 n profiles and published relationships among genes, transcription factors (TFs), and proteins to cons

186 nimmoniana unravels several putative pathway genes, transcription factors and CYPs related to camptot

187 ression of ABA receptors, drought-responsive genes, transcription factors, and NCED3 were studied aft

188 Histone H3K4 methylation is connected to gene transcription from yeast to humans, but its mechani

189 in orchestrating insulin secretion and islet gene transcription has been demonstrated recently.

190 lated process, and stress-induced changes in gene transcription have been shown to play a major role

191 ciate with corepressor complexes and repress gene transcription; however, in this study, we have foun

192 ate, a component of bile, by altering global gene transcription in a manner consistent with a strateg

193 HIV-1 latency by inhibiting LTR-driven HIV-1 gene transcription in a nuclear factor kappa B-dependent

194 n a deeper understanding of the evolution of gene transcription in and between plant species, we perf

195 changes in storage lipid accumulation and on gene transcription in animals exposed to different effec

196 Nerve injury induces changes in gene transcription in dorsal root ganglion (DRG) neurons

197 and hence play a critical role in promoting gene transcription in eukaryotes.

198 Viral gene transcription in host cell assemblages revealed die

199 lial cells during infection and may modulate gene transcription in infected host cells.

200 diated hedgehog signaling and Gli-controlled gene transcription in living cells (IC50 = 230 nM), prov

201 plex network of cross-regulations to control gene transcription in macrophages for modulating inflamm

202 oteins are important regulators of virulence gene transcription in many pathogens; they also control

203 n minutes, leading to activation of bivalent gene transcription in mouse embryonic stem cells.

204 ulator of NF-kappaB to modulate inflammatory gene transcription in mouse macrophages.

205 ubiquitin-proteasome system (UPS) influences gene transcription in multiple ways.

206 clei have a direct role in the regulation of gene transcription in part by controlling the access of

207 y which glucagon and insulin increased FGF21 gene transcription in primary hepatocyte cultures.

208 nd pDC development to activate RAG1 and RAG2 gene transcription in pro- and pre-B cells.

209 can bind gene promoters and regulate target gene transcription in response to DNA damage.

210 unity by comparing M. tuberculosis and human gene transcription in sputum between human immunodeficie

211 en that these mutations do not increase late gene transcription in the absence of genome replication.

212 6 complex enhances extrachromosomal reporter gene transcription in the absence of HBx, restores repli

213 e concomitant H3K9me3 downregulation mediate gene transcription in the hippocampus and reverse age-de

214 mentous actin formation in the cytoplasm and gene transcription in the nucleus.

215 he physical nanoenvironment of chromatin and gene transcription in vitro.

216 ate that NKD1 and NKD2 can directly regulate gene transcription, including activation of opaque2 and

217 eset cells, appearance of biallelic X-linked gene transcription indicates reactivation of the silence

218 Alternatively, measuring the levels of gene transcription is a direct method of analysing the H

219 a (MKL)/serum-response factor (SRF)-mediated gene transcription is a highly conserved mechanism that

220 Gene transcription is carried out by RNA polymerases (RN

221 We sought to define how dysfunctional gene transcription is causally linked to the degree of T

222 Nuclear gene transcription is coordinated with transcript releas

223 GLK1 gene transcription is directly repressed by PHYTOCHROME-

224 and the recruitment of cofactors to regulate gene transcription is essential.

225 ERalpha and ERbeta regulation of gene transcription is further modulated by tissue-specif

226 accessibility, indicating that HFD-regulated gene transcription is primarily controlled by modulating

227 ding sites is critical for understanding how gene transcription is regulated across different cell ty

228 Eukaryotic gene transcription is regulated at many steps, including

229 We conclude that RUNX2 gene transcription is regulated by the methylation statu

230 ncing reveals that this mechanism of altered gene transcription is restricted and that the majority o

231 he positive feedback located at the level of gene transcription) is superior in describing the experi

232 egulation, and its subsequent effect on host gene transcription, is dynamic rather than locked in a s

233 st time, allows users of Lux assays to infer gene transcription levels from the light output.

234 elated and both have a similar dependence on gene transcription levels.

235 e demonstrate that these directed changes in gene-transcription levels occur with minimal off-target

236 gs suggest that variations in SP110-mediated gene transcription may underlie, at least in part, the v

237 ntified in this study can shed lights on the gene transcription mechanism under long-range chromatin

238 ed neuroprotection, a synaptic activity- and gene transcription-mediated increase in the resistance o

239 P-ribose polymerase 1 (PARP1), whose role in gene transcription modulation has been well established.

240 n levels are dictated by the balance between gene transcription, mRNA translation, and protein degrad

241 in, acting on multiple receptors to regulate gene transcription, neural function, and behavior.

242 Many features of how gene transcription occurs in human cells remain unclear,

243 ) via MAPK signaling pathways that stimulate gene transcription of the common alpha-subunit (Cga) and

244 orticosteroid receptors, or by inhibitors of gene transcription or protein synthesis, but was blocked

245 the development of inhibitors that modulate gene transcription or signaling pathways.

246 pressin signaling selectively increases Aqp2 gene transcription or whether it triggers a broadly targ

247 T5 DNA-binding activities, STAT3-independent gene transcription, or activation of a panel of oncogeni

248 nduce both the pro-survival NF-kappaB-driven gene transcription pathway and the pro-apoptotic caspase

249 nique nuclear localization and regulation of gene transcription pathways by SmgGDS.

250 expression by affecting chromatin structure, gene transcription, pre-mRNA processing, or aspects of m

251 It is widely accepted that cAMP regulates gene transcription principally by activating the protein

252 e of the data and the stochastic dynamics of gene transcription process.

253 distinct taxonomic, metabolic potential, and gene transcription profiles.

254 LFA-1 stimulation in T lymphocytes modulates gene-transcription programs, including genetic signature

255 > G (rs3814159) is associated with increased gene transcription, protein expression, CD39/NTPDase1 en

256 a poor substitute for TF activity levels and gene transcription rates.

257 n cortical VIP neurons, experience-dependent gene transcription regulates visual acuity by activating

258 rtant epigenetic marker that associates with gene transcription regulation.

259 Control of gene transcription relies on concomitant regulation by m

260 Eukaryotic gene transcription requires the assembly at the promoter

261 tors and epigenetic modifications that drive gene transcription responsible for unique cell fate.

262 selective targeting of p65 and its effect on gene transcription reveals unique mechanisms by which pa

263 n five biological processes: RNA processing; gene transcription; ribosomal proteins; protein degradat

264 scence-associated secretory phenotype (SASP) gene transcription signature.

265 In practice, variants near gene transcription start sites (TSSs) or certain histone

266 These results support previous gene transcription studies and extend the observation of

267 Gene transcription studies have identified dual roles fo

268 nclude that inhibitors of MRTF/SRF-regulated gene transcription such as CCG-222740, potentially repre

269 mulated response gene and a repressor of IFN-gene transcription, suggesting the existence of a negati

270 eir functional significance at the levels of gene transcription, synaptic regulation, and behavior.

271 t deguelin treatment significantly increases gene transcription that is associated with energy metabo

272 AC inhibitors exert positive effects on Bdnf gene transcription, the inhibitors represent small molec

273 Enhancers, which activate gene transcription, themselves undergo Pol II-mediated t

274 Histone deacetylase 1 activates PU.1 gene transcription through regulating TAF9 deacetylation

275 d to affect development by regulating target gene transcription through T3 receptors (TRs).

276 ted by glucose-dependent activation of GLUT4 gene transcription through the cis-acting GLUT4-liver X

277 Strategies to alter gene transcription through these structures thus far inv

278 Estrogen receptor alpha (ERalpha) regulates gene transcription through two activation functions (ERa

279 cle through integration but suppressed HIV-1 gene transcription, thus allowing the establishment of l

280 gnaling, which directly regulates cell-cycle gene transcription to control a reversible G1 cell-cycle

281 e cell signaling pathways and reprogram host gene transcription to promote survival in the mononuclea

282 lar mechanisms regulating activity-dependent gene transcription upon activation of the CREB/CRTC1 sig

283 signaling-dependent epigenomic regulation of gene transcription using a few representative cancer-rel

284 erties of IE collected on admission, and var gene transcription using quantitative polymerase chain r

285 We discovered that HDAC1 activates PU.1 gene transcription via deacetylation of TATA-binding pro

286 naling pathway in which BMP-2 activates Dspp gene transcription via Dlx3/Osx pathway.

287 KK1/2-Erk1/2 signaling and by blocking c-Jun gene transcription via inactivation of MKK4-JNK1/2 signa

288 r function in CLL cells, stimulating PKCbeta gene transcription via increased association of SP1 and

289 g complex negatively controls STAT1-mediated gene transcription via interferon stimulated response el

290 of mosquito and host passage on in vitro var gene transcription was investigated.

291 STAT3-driven gene transcription was required for LTD as inhibition of

292 hat these changes may be related to abnormal gene transcription, we lack an understanding of the biol

293 Instead of silencing gene transcription, we showed that the GAD1 promoter was

294 , and viral DNA synthesis and early and late gene transcription were inhibited.

295 lar RNA polymerase II available for cellular gene transcription, which consequently impaired cellular

296 6) promoter acting to markedly repress basal gene transcription, which responds to both the Ets domai

297 n of cytokines was regulated at the level of gene transcription, which was dependent on activation of

298 tant role in inhibiting cancer cell-specific gene transcription while also facilitating anti-cancer g

299 Glycolysis is necessary for early gene transcription, while glutaminolysis is necessary fo

300 .MicroRNAs (miR) are important regulators of gene transcription, with miR-155 and miR-146a both impli