ライフサイエンスコーパス: generation time

1 ge individuals resulted in a doubling of the generation time.

2 n so far as they are regulated by changes in generation time.

3 a positive linear relationship between U and generation time.

4 cialization and small body size but not with generation time.

5 ing confidence in estimates of a short viral generation time.

6 itations such as expense and the long canine generation time.

7 of organismal cellular complexity, size, and generation time.

8 es, including metabolic rate, body size, and generation time.

9 a(2+) efflux and that ATP levels also affect generation time.

10 d in mammalian species because of their long generation time.

11 ity, independent of phylogeny, body size and generation time.

12 for sexually reproducing species with short generation times.

13 eterious mutation rates in lines with longer generation times.

14 ain gorillas to directly infer their average generation times.

15 s, and their plasmas have increased thrombin generation times.

16 baceous plants, which generally have shorter generation times.

17 on that may reflect differences in long-term generation times.

18 fivefold in both cell types, increased cell generation time 1.9-fold, on average, in 32D cl3 cells a

19 H. dujardini has a short generation time, 13-14 days at room temperature.

20 geny cells was persistent through the second-generation time (~240min) until all of the progeny cells

21 When geological dating, an assumed generation time (25 years), and an estimated divergence

22 s lost their cell-bound QDs during the third generation time (~360min).

23 Within a single generation time a growing yeast cell imports approximate

24 itutive) in constant environments at several generation times across a range of concentrations of arg

25 Due to the short generation time, advantages of haplodiploidy, and availa

26 This correspondence between generation time, an evolutionary parameter, and temperat

27 han carnivores and birds because of a longer generation time and a larger sex difference in the numbe

28 ate with certain species attributes, such as generation time and body size.

29 Here, we measure the photovoltage generation time and find it to be faster than 50 fs.

30 ubly mutant bacteria had a greatly prolonged generation time and grew as filamentous chains in liquid

31 of orthologous loci in organisms similar in generation time and in the number of germline cell divis

32 The long generation time and large effective size of widespread f

33 a mouse model to take advantage of its short generation time and lifespan.

34 lly, there is a positive correlation between generation time and mt GC content.

35 A positive correlation between the generation time and percent killing of intracellular bac

36 ed as the reciprocal of twice the product of generation time and the coalescence probability.

37 ations are likely, depending on the species' generation time and the speed of temperature change.

38 raphic features that significantly influence generation time and therefore the rate of mutation.

39 and proteomic studies is limited by its long generation time and unsequenced pseudotetraploid genome.

40 estricted to model organisms that have short generation times and are easily propagated in the labora

41 pensive are worms or flies, which have short generation times and can be rapidly screened for mutatio

42 12), we calculated viral clearance rates and generation times and estimated the loss of BKV-infected

43 With extremely short generation times and high mutability, many viruses can r

44 ch using RNA viruses as replicons with short generation times and high mutation rates has been an inv

45 ccumulate genetic variation because of short generation times and high mutation rates.

46 esumably effective population sizes), faster generation times and high rates of gene flow with other

47 l and matrix neurons are influenced by their generation times and local environments, and that future

48 Evidently, discordance is a product of long generation times and moderately large effective populati

49 ck." We consider the effects of sex-specific generation times and mutation rates in species with two

50 parasites and pathogens tend to have shorter generation times and often experience stronger selection

51 mic and for the first time co-estimate viral generation times and superspreading events from a combin

52 tants displayed a 20-30% increase in average generation time, and comparable decreases in rates of st

53 germline from the effects of metabolic rate, generation time, and other factors, we allowed mutations

54 was used to estimate the incubation period, generation time, and within-school reproductive number a

55 e clonal strategy is based on survival, long generation times, and is associated with tolerance of he

56 rowth approximately 8 mM but with V(max) for generation time approximately 1 h 10 min); the fructose

57 When differences in generation time are considered, we find an exponential i

58 of mammals, we show that both longevity and generation time are significantly correlated with the nu

59 opulation genetics ignores forced changes in generation time as rare advantageous alleles sweep into

60 cies with the highest value of S, can have a generation time as short as 7 min.

61 We investigated the effect of generation time (as controlled by chemostat flow rate) a

62 ow in trees and shrubs, with relatively long generation times, as compared with related herbaceous pl

63 Generation times at these optimal temperatures ranged fr

64 red, manifested by a reduction in body size, generation time, brood size and lifespan.

65 is associated with large body size and long generation time but is not associated with degree of spe

66 ation, other aspects of the system limit the generation time, chiefly the propensity of the substrate

67 t genetic model organisms owing to its short generation time, comparatively large litters, ease of hu

68 r onset of reproduction leading to shortened generation times could explain the persistence of therap

69 days on average, and that the average HIV-1 generation time--defined as the time from release of a v

70 Calculated generation times during exponential phase were 10.2 h (b

71 s, and felids) than for organisms with short generation times (e.g., rodents) since the former underg

72 The model also implies that the "generation time effect" should be stronger in short-live

73 substitution rate than human, supporting the generation-time effect hypothesis.

74 ammalian evolution as a result of changes in generation times, effective population sizes, and recomb

75 DR genes in mammals appear to be subject to generation time effects in ways similar to those found a

76 re recruited to give viable recombinants 1-2-generation-time equivalents after formation of the initi

77 We then compare these generation time estimates with those of humans and apply

78 ze or age at first reproduction (a proxy for generation time) explains patterns of rate variation bet

79 t significant result being a 73% increase in generation time for JLS247.

80 r lag phase (entry plus differentiation) and generation time for the ocular strains.

81 rces and estimated the incubation period and generation time from case cluster data.

82 The predicted crypt generation time from one SC is 4-5 days with 10-12 days

83 r in short-lived species, explaining why the generation time has a major influence on yearly substitu

84 sperms (e.g. herbaceous habit, short minimum generation time) has enabled them to exploit new niches

85 effect, whereas relative mutation rates and generation times have little effect.

86 This study supports the generation time hypothesis for rate variation in the nuc

87 by a reduced number of progeny and prolonged generation time in high NaCl.

88 ry traits that led to a substantially longer generation time in humans than in other hominoids.

89 sence of arginine yet becomes independent of generation time in the presence of excess arginine.

90 with respect to argR(B) declines with longer generation times in the absence of arginine yet becomes

91 ore early transmission resulted in a shorter generation time, in which case lower values for the basi

92 rameters from the mean-field epidemic (R(0), generation time, infectiousness, etc.) are preserved in

93 Generation time is an important determinant of a neutral

94 enetic underpinnings of longevity, since its generation time is brief and both the genetic background

95 Indeed, a long generation time is considered an important trait that di

96 Furthermore, control over the pair generation time is essential for scaling many quantum in

97 ns on invertase secretion are additive, cell generation time is increased 60%, and cells become sensi

98 its the distinct lag and log phases, but the generation time is more than twice longer than in bulk m

99 ble and useful even though a relatively long generation time is required.

100 Because generation time is unknown in this lizard and estimates

101 derstanding how life history parameters like generation time, life expectancy and the variance in lif

102 Long generation times limit species' rapid evolution to chang

103 emission process leads to long entanglement generation times, limiting realized network implementati

104 Molecular clock variation due to generation time may help to resolve the discordance betw

105 e various determinants of evolutionary rate: generation time, mutation rate, population size, and the

106 confounding factors, such as differences in generation times, mutation rates and demography, we conc

107 ot replicate in freshly explanted monocytes (generation time of >400 h); BCG replicated with a genera

108 polymerase chain reaction, which suggested a generation time of 4 days.

109 ation time of >400 h); BCG replicated with a generation time of 95 h, and M. tuberculosis strains CDC

110 The mean generation time of a panel of clinical isolates was comp

111 ia isolate is a slow-growing organism with a generation time of approximately 30 h and produces popul

112 ts half-life were short in comparison to the generation time of hepatocytes and if new cccDNA formati

113 The generation time of HIV Type 1 (HIV-1) in vivo has previo

114 s-producing CD4(+) T cells, 0.7 day, and the generation time of HIV-1 in vivo, approximately 2 days,

115 acterium Vibrio natriegens can double with a generation time of less than 10 min, a growth rate that

116 se subpopulations (Ne = 205) and the average generation time of this species in the subtropics (in th

117 The large genome size and long generation time of this species present obstacles to bot

118 ins CDC551, H37Rv, and H37Ra replicated with generation times of 24, 35, and 37 h, respectively, duri

119 tant grows faster than the wild-type strain (generation times of 37.5 and 60 min, respectively, in Du

120 stigation, we observed that (i) the in vitro generation times of flgM mutant and wild-type strains of

121 stochastic models for the lag and subsequent generation times of individual cells are analysed.

122 However, the tetraploidy genome and long generation-time of the common carp have made its breedin

123 ents of the starches were positive, as ozone generation time (OGT) increased.

124 , we characterize the impact of noise in the generation-time on cell-to-cell variability.

125 mpact of two factors, genomic background and generation time, on deleterious mutation in Daphnia puli

126 time was much more prolonged than was force generation time or active force return time.

127 breeding range size, non-breeding location, generation time or body size.

128 clock, by postulating effects attributed to generation-time, population size, slightly deleterious m

129 Due to its small size, rapid generation time, powerful genetic systems, and genomic r

130 significantly higher for organisms with long generation times (primates, perissodactyls, and felids)

131 dscape of single mother cell through several generation times (progeny cells).

132 Analysis of the budding pattern and generation time showed that the slower proliferation of

133 s the experimental populations but with long generation time, showed that the number of surviving off

134 Its highly selfing nature, small size, short generation time, small genome size, and wide geographic

135 Microbial generation time, supply of nitrite relative to nitrate,

136 environments, frequency-dependent changes in generation times tend to counteract these invasions.

137 nd is very active (0.39 muM) in the thrombin generation time (TGT) coagulation assay in human platele

138 n the high-mortality populations relative to generation time than it does in the low-mortality popula

139 it markedly accelerated the increase in cell generation time that is observed during yeast aging.

140 ons, an analytic relation is derived between generation time, the average length of the cell cycle, a

141 Depending on the assumed generation time, the onset of the decline was dated betw

142 alescence theory that allows the estimate of generation times to be derived by using nucleotide seque

143 n analytic relation between temperature, and generation time, to show that the directionality princip

144 In species with short generation times, U is predicted to be far below 1, sugg

145 pe and was accompanied by a 10% reduction in generation time under these conditions.

146 The estimate of viral generation time using the coalescent method is 1.2 days

147 The estimated median generation time was 2.7 days (95% CI, 2.0 to 3.5).

148 The mean generation time was 3.39 d [3.06, 3.70].

149 mated population growth rate Ro was 1.69 and generation time was 7.8 years.

150 nt-rich media and defined media in which the generation time was approximately tripled.

151 Generation time was found to have a greater effect on mu

152 Generation time was shortened by selection, a change tha

153 ulture ( approximately 6 h, 1 day and 2 week generation times), we observe the greatest anabolic acti

154 for individuals maintained at two different generation times, were quantified and compared.

155 Our results reveal S. aureus generation times with a median of 2.1 d, with extensive

156 This method requires only information on generation time without other specific details regarding

157 r influence of human pressure whereas longer generation times would favor a climate-induced origin of

158 Shorter generation times would favor a stronger influence of hum