ライフサイエンスコーパス: genesis

1 n unfavorable (favorable) environment for TC genesis.

2 t the network mechanisms responsible for its genesis.

3 c changes that are directly related to tumor genesis.

4 herapeutic target for limiting breast cancer genesis.

5 on of the hair cell early during hair-bundle genesis.

6 w be formulated for optimal osteo- and angio-genesis.

7 t the central role of PTCH1 mutations in BCC genesis.

8 te conditions conducive to endogenous tissue genesis.

9 ortant roles in perinatal neuro- and synapto-genesis.

10 F-kappaB-mediated BACE1 expression and Abeta genesis.

11 an important source rock for Archean crustal genesis.

12 -defined RGC classes are born throughout RGC genesis.

13 on in the cerebellum hinders medulloblastoma genesis.

14 ng engineered material and even regulate its genesis.

15 ls, thymic T cell development and lymph-node genesis.

16 ripts) that play an important role in cancer genesis.

17 pment, implying that Oc1 is essential for HC genesis.

18 normal neovessels at an early stage of their genesis.

19 gastric and extragastric factors in symptom genesis.

20 e solid pools, consistent with enhanced soil genesis.

21 rdination, innate fear behavior, and seizure genesis.

22 essential variable in normal endocrine cell genesis.

23 architectural unit for multicellular tissue genesis.

24 e of the cellular microenvironment in tissue genesis.

25 anistic link between each risk factor and AF genesis.

26 characterization of these neurons and their genesis.

27 G neuronal excitability and neuropathic pain genesis.

28 Kindred Study [ISKS], 966 probands; Project GENESIS, 48 probands; Asan Bio-Resource Center, 138 prob

29 At the genesis, a bilayer's response to osmotic force is likely

30 s in both OB-dependent and cell-intrinsic OC-genesis, a phenotype opposite to that of the Zfp521 knoc

31 es that can be related to differences in the genesis and clinical evolution of these types of breast

32 s a variety of natural processes such as ore genesis and crystallization induced fracturing that can

33 Genetic signals were enriched in neuronal genesis and differentiation pathways, and substantial ge

34 Genetic signals were enriched in neuronal genesis and differentiation pathways, and substantial ge

35 The genesis and dynamics of autoreactive B cells remain unkn

36 oss-link is a fundamental requirement in the genesis and evolution of epithelial tissues by determini

37 nd SH2 modulation, network rewiring, and the genesis and extinction of phosphorylation sites.

38 SSTs generally correlate with more frequent genesis and greater potential intensity, while VWS inhib

39 xpanded range of metal cation templates; the genesis and growth of anion templation, as well as the u

40 egulate cell behavior and function in tissue genesis and homeostasis.

41 Another key factor that governs the genesis and intensity of hurricanes is ambient environme

42 oscientists can identify the site of seizure genesis and its spatial progression during various the s

43 YC enhancer activation may contribute to the genesis and localisation of MYC-Immunoglobulin transloca

44 nscription factor GATA3 is essential for the genesis and maturation of the T cell lineage, and GATA3

45 ed detail is now providing insights into the genesis and molecular underpinnings of this disease.

46 allow heparanase to play a role in exostosis genesis and pathogenesis, thus making it a conceivable t

47 We discuss the genesis and persistence of this belief in the light of t

48 Lgl1 functions controlling RGP-mediated glia genesis and postnatal NSC behavior.

49 ater potential intensity, while VWS inhibits genesis and prevents any hurricanes that do form from re

50 family of receptors that are involved in the genesis and progression of a number of cancers.

51 ve been documented to play a key role in the genesis and progression of alcoholic liver disease with

52 omas suggests that it also has a role in the genesis and progression of benign tumors.

53 Estrogen has a central role in the genesis and progression of breast cancers whether they a

54 on in developmental processes as well as the genesis and progression of cancers.

55 hysiological processes and contribute to the genesis and progression of cardiovascular diseases.

56 Elevated SOX9 is implicated in the genesis and progression of human tumors by increasing ce

57 In spite of significant technical advances, genesis and progression of non-small cell lung cancer (N

58 ghly expressed in HCC and contributes to its genesis and progression, we analyzed the involvement of

59 vidence that NR2A subunit contributes to CSD genesis and propagation, suggesting drugs selectively an

60 s Yap and Taz as key early regulators of RPE genesis and provides a mechanistic framework for underst

61 Administration DC-8 platform during the 2010 Genesis and Rapid Intensification Processes campaign in

62 ll wall; yet, the regulation of Pc cell wall genesis and remodeling is not well understood.

63 evidence for the involvement of PRG5 in the genesis and stabilization of dendritic spines.

64 sistent with replication-based models of CGR genesis and strongly argue that nonhomologous repair of

65 ion of GATA-2, which is known to promote the genesis and survival of hematopoietic stem cells.

66 ariability through its relationship with the genesis and thermodynamic potential intensity of hurrica

67 deregulation is often associated with tumor genesis and tumor growth.

68 The genesis and unique properties of the lymphovascular tumo

69 ncreased OB-dependent osteoclastogenesis (OC-genesis), and deletion in hematopoietic cells revealed a

70 d in lipid transfer, cholesterol efflux, HDL genesis, and remodeling at the BBB.

71 tropical precipitation and tropical cyclone genesis, and these changes have been tied to the weakeni

72 rve to unravel intrinsic differences in bone genesis by endochondral and intramembranous mechanisms.

73 ical model to predict the dynamics of tissue genesis by periosteal progenitor cells within a long bon

74 g properties of Gag that occur during virion genesis, coincident with membrane binding, multimerizati

75 is both timely and relevant in outlining the genesis, development, and future of this paradigm shift

76 cle regulator, is involved in regulating the genesis, differentiation and death of retinal cells.

77 nhardtii cell wall and analysis of cell-wall genesis during cell division.

78 Their genesis during development is subject to regulation by t

79 criptional networks leading to photoreceptor genesis during retinal development.

80 thymocyte development and normal lymph-node genesis, except for Peyer's patches.

81 ic novelty, and many questions regarding its genesis, fate and evolutionary role remain unanswered.

82 , it is usually too late to understand their genesis for efficient management.

83 d with the perturbation of secretory vesicle genesis from the TGN.

84 e and Insulin-related traits Consortium) and GENESIS (GENEticS of Insulin Sensitivity) studies.

85 truction shares distinct traits with pallial genesis in mammals and non-mammalian amniotes such as bi

86 (+9.5) required for hematopoietic stem cell genesis in mice is mutated in a human immunodeficiency s

87 it as the driving force underlying amplicon genesis in our samples.

88 nd temporal resolution, we show that granule genesis in Pseudomonas aeruginosa is tightly organized u

89 ty to CSD, but also reduced magnitude of CSD genesis in rats.

90 d, bone marrow transplantation (BMT) has its genesis in rodent models dating back to the 1950s.

91 ns article, I have tried to follow up on the genesis in the 1960s and subsequent evolution of the con

92 we quantitatively analyzed excitatory neuron genesis in the mouse neocortex using Mosaic Analysis wit

93 l-like receptor (TLR) 4 signaling induces OL genesis in the naive spinal cord, and lack of TLR4 signa

94 at excitation may not be essential for gamma genesis in this region.

95 however, whether these receptors mediate CSD genesis in vivo requires clarification and the role of N

96 -like laminin networks, in addition to their genesis in vivo, are integral to the extracellular archi

97 or nonprimate-primate differences in cortico-genesis include the dimensions, precursor lineages, and

98 abetes-related traits in GWAS meta-analyses (GENESIS [including RISC, EUGENE2, and Stanford], MAGIC,

99 Gag protein orchestrates all steps of virion genesis, including membrane targeting and RNA recruitmen

100 isplayed features consistent with reduced OL genesis, including reduced NG2 expression, fewer BrdU-po

101 l environment associated with nascent tissue genesis influence the strain stimulus sensed by progenit

102 Our observations suggest that exopher-genesis is a potential response to rid cells of neurotox

103 e to diverse environmental stresses, granule genesis is poorly understood.

104 tly associated with embryonic somatic tissue genesis, is the one that encodes the specific factors to

105 an be used for CHARMM, NAMD, GROMACS, AMBER, GENESIS, LAMMPS, Desmond, OpenMM, and CHARMM/OpenMM.

106 emain uncertain, particularly in terms of TC genesis locations and subsequent pathways.

107 anges in steering flow instead of changes in genesis locations.

108 uished: (1) induced control, where organelle genesis, maintenance, and disassembly are three separate

109 te several cellular processes, including the genesis, maintenance, and plasticity of synapses.

110 momentarily labile-with implications for the genesis, maintenance, and treatment of PTSD.

111 ciated role of epigenome deregulation in the genesis of 13% of HPV-negative HNSCCs.

112 ing pathways that play critical roles in the genesis of a large number of human cancers.

113 We postulate that this step in the genesis of a pandemic virus only occasionally occurs in

114 erization in vitro but was necessary for the genesis of a perinuclear-concentrated network of keratin

115 Microbial species participate in the genesis of a substantial number of malignancies-in conse

116 ancestrally may also have contributed to the genesis of A(H7N9) viruses, we inferred historical evolu

117 tand the role of individual mutations in the genesis of actin- and tropomyosin-related diseases and w

118 channels, a fundamental prerequisite for the genesis of action potentials.

119 elucidates novel mechanisms involved in the genesis of acute herpetic neuralgia and open new avenues

120 elucidates novel mechanisms involved in the genesis of acute herpetic pain and open new avenues for

121 dissatisfaction might also contribute to the genesis of adverse outcomes themselves.

122 s that SCN10A variations are involved in the genesis of AF.

123 n lens cell membranes may play a role in the genesis of age-related eye disorders.

124 A structural understanding of the genesis of aggregates and their modulation by cellular c

125 The processes involved in the genesis of allergic sensitization remain elusive.

126 ct amino acid-nucleobase interactions in the genesis of amino acid-based ribosomal components.

127 events in tumor evolution, especially in the genesis of amplicons.

128 The genesis of apoptosis and necrotic cores in these vulnera

129 myofibrillar myopathies, suggesting that the genesis of ariel aggregates follows a pathogenic pathway

130 immune response that plays a key role in the genesis of atherosclerosis.

131 bsequent to induced neural imbalances in the genesis of atrial fibrillation (AF).

132 fragments, which may provide clues about the genesis of autoimmune diseases such as systemic lupus er

133 ibitory cells are dominantly involved in the genesis of beta- and gamma-oscillations, as well as in t

134 The genesis of beta-cells predominantly occurs through self-

135 echanism of action of aromatic amines in the genesis of bladder cancer is not, however, fully delinea

136 age, indicating that ET-1 is involved in the genesis of brain microvascular alterations that are the

137 We also link the genesis of Bronsted acidity to the surface coverage of a

138 t to our knowledge are new insights into the genesis of Ca(2+) alternans and spontaneous second Ca(2+

139 lopment and could play a similar role in the genesis of cancer.

140 high mutation rates are dispensable for the genesis of cancers driven by mutation of a chromatin rem

141 factor that may primarily contribute to the genesis of cardiac arrhythmias in Timothy Syndrome.

142 -isotope imaging mass spectrometry--that the genesis of cardiomyocytes occurs at a low rate by the di

143 ne the potential role of mitochondria in the genesis of cardiovascular disease such as ischemia and h

144 nce in these mouse models may illuminate the genesis of chemoresistance in human liver cancer.

145 The molecular mechanisms underlying the genesis of cholangiocarcinomas (CCs) are poorly understo

146 dendritic cell immunoreceptor (DCIR) in the genesis of CM.

147 ication underlies all brain activity and the genesis of complex behavior.

148 signaling is abnormally regulated during the genesis of congenital intrinsic ureteropelvic junction o

149 A long-standing theory for the genesis of continental crust is that it is formed in sub

150 FEV1 in early adulthood is important in the genesis of COPD and that accelerated decline in FEV1 is

151 ns of activating the EGFR pathway during the genesis of CRC and potentially other cancers.

152 demonstrate the involvement of COX-2 in the genesis of CSFTCs and suggest that COX-2 inhibitors shou

153 ycle, HFD causes an unexpectedly large-scale genesis of de novo oscillating transcripts, resulting in

154 reward pathways contributes, in part, to the genesis of depression.

155 whether MCT abnormalities contribute to the genesis of disease or whether they are secondary manifes

156 e expanded the role of ubiquitination in the genesis of diverse lymphoid malignancies.

157 of a multi-step evolutionary process in the genesis of dmin/hsr.

158 sufficiency as the most likely cause for the genesis of dominant ARVC due to mutations in PKP2.

159 and, in addition, LXRbeta is involved in the genesis of dopaminergic neurons during development and p

160 which likely plays an important role in the genesis of dysphagia and delayed esophageal emptying.

161 subsequent sedimentation may account for the genesis of enigmatic barite deposits.

162 This network dictates the genesis of enucleated erythrocytes by orchestrating the

163 The nature of neuroadaptations in the genesis of escalated cocaine taking remains a topic of c

164 d neurons is important for understanding the genesis of extracellular potentials, as well as for loca

165 ucleus of the stria terminalis (BNST) in the genesis of fear versus anxiety, respectively.

166 nin is an important signaling pathway in the genesis of fibrosis in many organ systems.

167 By modeling the genesis of genomic rearrangements, we identified abundan

168 gh multiple genes are likely involved in the genesis of HAPH, to date no major gene variant has been

169 inal cell types, including completely failed genesis of HCs, compromised generation of cones, reduced

170 at the sensory ganglia that account for the genesis of herpetic neuralgia using a murine model of He

171 sensory ganglia play a critical role in the genesis of herpetic neuralgia.

172 We provide a model for the genesis of Holocene coralligenous buildups occurring in

173 n, and T-cell activation is required for the genesis of hypertension.

174 and inflammation are both implicated in the genesis of hypertension; however, the mechanisms by whic

175 cohort of patients, providing insights into genesis of hypomethylation in myeloma.

176 We demonstrate that IFNalpha inhibits the genesis of infectious extracellular HCV particles within

177 w the contribution of the single IOLs to the genesis of inflammation.

178 s released in the DRG and contributes to the genesis of inflammatory hypernociception.

179 ative GTPase-driven signaling pathway in the genesis of inhibitory synapses.

180 of human, but not mouse, FoxP2 enhances the genesis of intermediate progenitors and neurons.

181 rther studies are necessary to determine the genesis of intracellular RR and elucidate the clinically

182 Reactive oxygen species are critical for the genesis of ischemic AKI.

183 ions, suggesting a role for this gene in the genesis of leiomyomas.

184 ventricular myocytes, which is linked to the genesis of lethal arrhythmias.

185 Tyrosine kinase oncoproteins promote the genesis of leukemias through both increased cell prolife

186 ring properties is possibly important on the genesis of local field potentials, as well as on the cab

187 errations may play a significant role in the genesis of lung cancers lacking known driver mutations.

188 s expressed locally that are involved in the genesis of lymphatic vessels in the normally avascular c

189 have previously shown that HSV-1 elicits the genesis of lymphatic vessels into the cornea proper thro

190 anding of how these events contribute to the genesis of lymphomas.

191 atenin signaling are important events in the genesis of many cancers including skin cancer and are of

192 The MYC oncogene contributes to the genesis of many human cancers.

193 for other species to exploit, leading to the genesis of many new taxa in a process termed "sequential

194 ed, role of the meningeal vasculature in the genesis of migraine pain.

195 To provide insights into the genesis of modern GAS puerperal sepsis, we reviewed the

196 he neurobiological changes implicated in the genesis of mood disorders or dementia have not been iden

197 (SMA)--a region strongly associated with the genesis of motor tics in TS--are paradoxically elevated

198 of the role of these reserve EC cells in the genesis of multifocal SI-NETs could improve diagnostic a

199 and more central role of the thalamus in the genesis of multiple distinct thalamo-cortical rhythms th

200 Cyclin D1 deregulation is implicated in the genesis of multiple human cancers.

201 in for transverse tubule function and in the genesis of muscular dystrophy.

202 Genesis of natural biocomposite-based materials, such as

203 iTreg by TGF-beta were decreased whereas the genesis of natural Treg (nTreg) remains normal.

204 the physiological mechanisms involved in the genesis of nausea remains lacking.

205 RNA translation during synaptogenesis in the genesis of neurodevelopmental disorders.

206 ation, and simultaneously contributes to the genesis of obesity and asthma.

207 CHC22 in neural crest development and in the genesis of pain and touch sensing neurons.

208 function has been shown to contribute to the genesis of particular cancers, its global functional con

209 ons in affecting the potential intensity and genesis of past TCs and suggests that both factors may h

210 bility of DRG neurons and contributes to the genesis of pathological pain.

211 ime-locked spikes in the STN, explaining the genesis of PD-associated pathological bursts and synchro

212 herefore provide the oxidized source for the genesis of primary arc magmas that release gases to the

213 lts establish a new function for Cas9 in the genesis of prokaryotic immunological memory.

214 inergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points

215 electrophysiology, which participate in the genesis of pump failure and related arrhythmias, both in

216 electrophysiology, which participate in the genesis of pump failure and related arrhythmias, both in

217 of both Olig2 and Olig1 results in impaired genesis of Purkinje cells (PCs) and Pax2(+) interneurons

218 The APC results suggest that the genesis of racial disparities is neither static nor rest

219 spatial vulnerabilities of atrial tissue to genesis of re-entry were computed.

220 non-cell-autonomous events that lead to the genesis of renal dysplasia.

221 rods, and cell-lineage tracing validated the genesis of rods from S cones.

222 d and infected cells and participates in the genesis of several inflammatory diseases.

223 into the dynamics of sex chromosomes and the genesis of sexual dimorphism.

224 The genesis of short APs lasting milliseconds is well unders

225 ependence, suggesting their relevance in the genesis of signs and/or symptoms affecting ethanol withd

226 ere we provide evidence that FoxP2 regulates genesis of some intermediate progenitors and neurons in

227 tention to varying degrees to understand the genesis of spatial processing in the amygdala.

228 derstanding of biogenesis mechanisms and the genesis of specific expression profiles for tRNA-derived

229 ts associated transcription factor Gli1 with genesis of specific neuronal progeny.

230 arteriopathy is the initiating event in the genesis of steroid-induced osteonecrosis and provides a

231 Inflammation has been linked to the genesis of stroke in atrial fibrillation (AF) and is imp

232 We explored the genesis of such resistance by studying mouse models of l

233 agation of cytoplasmic calcium waves and the genesis of systolic Ca(2+) alternans in cardiac myocytes

234 The thalamus plays a critical role in the genesis of thalamocortical oscillations, yet the underly

235 he systemic pool-I will discuss the emerging genesis of the adipocyte over the past 20 years from met

236 The genesis of the ANCA autoimmune response is a multifactor

237 reveals that the principal mechanism for the genesis of the BCG waves is blood pressure gradients in

238 endrocyte maturation and is critical for the genesis of the central myelin sheath.

239 omponents of the dynamic cytoskeleton in the genesis of the disease.

240 The genesis of the electrocardiographic T wave is incomplete

241 define a niche-like environment guiding the genesis of the endocrine pancreas and advance current mo

242 Here we review the historical genesis of the idea and assess anthropogenic signatures

243 tion of SGCs and is thus responsible for the genesis of the inflammatory pain.

244 irolides and provided support for a proposed genesis of the new carbon skeletons.

245 epressor genes her1 and her7 are crucial for genesis of the oscillations, which are thought to arise

246 ivity measurements were used to identify the genesis of the oxidation sites and to validate the migra

247 fully consistent mathematical model for the genesis of the pattern by coupling the reactive fluid-so

248 This paper looks back on the genesis of the pEAQ vectors and reviews their use so far

249 dings not only provide new insights into the genesis of the red cell membrane during human terminal e

250 s of the SMA can provide new insights on the genesis of the SMA syndrome, and a better understanding

251 APC) is considered an initiating step in the genesis of the vast majority of colorectal cancers.

252 ical host factors assisting VRC assembly and genesis of the viral replication compartment.

253 s complex (TSC) manifestations; however, the genesis of these abnormalities remains unclear.

254 To understand the genesis of these autoantibodies, we investigated the int

255 Genesis of these contacts involves signaling through c-S

256 latively little is known, however, about the genesis of these errors or their fitness consequences.

257 hlight a conserved role of Pax3 genes in the genesis of these feeding muscles of vertebrates.

258 A consistent generic model for the genesis of these periodically banded rocks is still lack

259 mental factors potentially contribute to the genesis of these sleep disorders.

260 However, the genesis of these small organic molecules and their mode

261 However, the mechanism for the genesis of these waves has remained elusive.

262 Still, our understanding of the genesis of this essential cell type is restricted to the

263 r, the mechanistic involvement of SHS in the genesis of this malignancy remains elusive.

264 rojection neurons (SPNs) are involved in the genesis of this movement disorder, the molecular basis o

265 t model will provide useful insight into the genesis of thrombosis in blood-wetted devices, and provi

266 To investigate collaborating events in the genesis of TNBC, we generated Met(mt) mice with conditio

267 t coronary spasm playing a major role in the genesis of transient left ventricular apical ballooning.

268 ) and basophils, have been implicated in the genesis of type 2 immunity.

269 enzyme activity, and demand imposed by local genesis of ultralarge multimers of von Willebrand factor

270 t roles in specific brainstem regions in the genesis of various aspects of abnormal breathing.

271 t into the role of inflammatory cells in the genesis of vascular dementia.

272 Genesis of ventricular arrhythmias involves a complex in

273 ransport by ANO1/TMEM16A is required for the genesis or maintenance of primary cilia.

274 a mediator of ulcerative colitis both in its genesis or maintenance.

275 analysis of the role of RAS/vitamin D in the genesis or severity of AP, particularly given the ready

276 of events is consistent with increases in a genesis potential index based on monthly mean global mod

277 ical wind shear and the resulting changes in genesis potential.

278 73 women and 636 men age 18 to 55 years from GENESIS-PRAXY (GENdEr and Sex determInantS of cardiovasc

279 Its genesis reflects the hybridization history that characte

280 The molecular mechanisms underlying their genesis remain, however, largely undefined.

281 microenvironment in enabling metazoan tissue genesis remains obscure.

282 thogenic/biological mechanisms underlying OS-genesis remains to be ambiguous.

283 a 24.4 kbp-fragment containing 10 essential genesis replaced with a 4 kbp-fragment containing three

284 It is now known that AF genesis requires a vulnerable atrial substrate and that

285 1, expression of which favor glio- and neuro-genesis, respectively.

286 However, the genesis, role, and function of Maurer's clefts remain el

287 coupled with VEGFA elicited lymphatic vessel genesis significantly above either factor alone as well

288 ctional studies: 1626 children aged 2-5 (the Genesis Study) and 2015 children aged 9-13 (the Healthy

289 anscription factor that is essential for the genesis, survival, and maturation of a variety of neuron

290 processes are more important to uranium ore genesis than previously understood.

291 ges in expression of genes involved in tumor genesis, the oncogenic potential of 2-hydroxyglutarate,

292 However, during virion genesis, this specificity transiently changes in a manne

293 c permit high-titer culture by affecting HCV genesis through increasing virus assembly and HCV fitnes

294 p a mechanistic mathematical model of tissue genesis using bone morphogenetic protein (BMP) to repres

295 To understand the process of hemangioma-genesis we characterized the progenitor hemangioma-deriv

296 only cis-element known to mediate stem cell genesis, we devised a strategy to identify functionally

297 possible biophysical mechanisms for seizure genesis, while preserving central invariant properties.

298 reveals a fascinating hierarchical particle genesis with novel topological fermions beyond the Dirac

299 Yet, the prediction of tissue genesis within - and the spatiotemporal healing of - pos

300 haviors like acoustic communication, but its genesis within the auditory pathway is not well understo