ライフサイエンスコーパス: genetic counseling

1 may be relevant background data in clinical genetic counseling.

2 l for a definitive diagnosis, prognosis, and genetic counseling.

3 ossible, which is important for clinical and genetic counseling.

4 ugh gamete donation, prenatal diagnosis, and genetic counseling.

5 ropriate management, long-term guidance, and genetic counseling.

6 the identification of disease modifiers, and genetic counseling.

7 erest for molecular genetic research and for genetic counseling.

8 acilitate definitive molecular diagnosis and genetic counseling.

9 s that have instituted carrier screening and genetic counseling.

10 of gene defects is essential for informative genetic counseling.

11 ificantly less often than colonoscopy before genetic counseling.

12 east cancer syndromes should be referred for genetic counseling.

13 cer with age and derived its implication for genetic counseling.

14 nto the study and 50% of enrollees completed genetic counseling.

15 sociated significantly with participation in genetic counseling.

16 rral, study enrollment, and participation in genetic counseling.

17 nown, thus creating significant problems for genetic counseling.

18 p or palate is an important consideration in genetic counseling.

19 d mutations, with important implications for genetic counseling.

20 irmation allowing appropriate prognostic and genetic counseling.

21 eived their DNA test results in concert with genetic counseling.

22 genetic make-up remains a core principle of genetic counseling.

23 peptide pyridinoline cross-links (ICTP), and genetic counseling.

24 rently pursuing appropriate medical care and genetic counseling.

25 tive surgery were provided in the context of genetic counseling.

26 ul for pre-symptomatic disease detection and genetic counseling.

27 e opportunity for disease prevention through genetic counseling.

28 d not be done without first providing formal genetic counseling.

29 ations, particularly for supportive care and genetic counseling.

30 ting in families affected with PH2 to aid in genetic counseling.

31 establish an etiologic diagnosis and affect genetic counseling.

32 drial genetics that complicate diagnosis and genetic counseling.

33 rmonogenesis, which is familial and requires genetic counseling.

34 Family education and individual genetic counseling.

35 etween nondirectiveness and directiveness in genetic counseling.

36 portant in the differential diagnosis and in genetic counseling.

37 nd process of pretest education and posttest genetic counseling.

38 G mutation received results and were offered genetic counseling.

39 t implications for treatment, prognosis, and genetic counseling.

40 of 226) herein, and should be considered in genetic counseling.

41 I disorders to ensure accurate diagnosis and genetic counseling.

42 ill have immediate impact on diagnostics and genetic counseling.

43 and transcriptome (tumor RNA) sequencing and genetic counseling.

44 identifies risk factors to be considered in genetic counseling.

45 ted care pathways, and enabled more accurate genetic counseling.

46 to enhance the accuracy of the prognosis and genetic counseling.

47 lications for recurrence risk estimation and genetic counseling.

48 s finding would carry clear implications for genetic counseling.

49 y significant variants, which may complicate genetic counseling.

50 hich also must be addressed in the course of genetic counseling.

51 Our results are important for prognosis and genetic counseling.

52 with abatacept, a CTLA-4 mimetic, and inform genetic counseling.

53 ven implications for prognosis, therapy, and genetic counseling.

54 SCO2 mutations is particularly important for genetic counseling.

55 s, appropriate molecular genetic testing and genetic counseling.

56 y percent of laboratories provided access to genetic counseling, 69% had a confidentiality policy, an

57 Genetic counseling about the potential risks and benefit

58 ate discrimination to support individualized genetic counseling, although discrimination varies acros

59 on surgical decision-making of pretreatment genetic counseling and BRCA1/BRCA2 testing among breast

60 s, differential access to and utilization of genetic counseling and cancer predisposition testing amo

61 osis colorectal cancer) is critical for both genetic counseling and cancer prevention.

62 l to genetic professionals for gene testing, genetic counseling and cancer risk management; and could

63 cology clinic and were prospectively offered genetic counseling and clinical genetics risk assessment

64 Genetic counseling and clinical presentation confirmed t

65 Traditional genetic counseling and disease education were provided i

66 founder mutation provides an opportunity for genetic counseling and early diagnosis of XP.

67 avoidably reshaped the customary practice of genetic counseling and established a new proposed paradi

68 ese findings have important implications for genetic counseling and for understanding patterns of rec

69 iagnosis of thyroid dyshormonogenesis allows genetic counseling and has prognostic value in different

70 5-bp deletion will facilitate more accurate genetic counseling and identification of other branches

71 s somewhat unique to genetic testing include genetic counseling and informed consent for genetic test

72 This genetic characterization will aid in genetic counseling and management, critically required t

73 using such an array may, thus, be useful for genetic counseling and may help clinical decision making

74 SCCOHT, which could lead to improvements in genetic counseling and new treatment approaches.

75 These findings have major implications for genetic counseling and patient management as new therape

76 nically challenging, but it is important for genetic counseling and perhaps for helping to select app

77 eworks should provide a useful procedure for genetic counseling and prenatal assessment of Rh alloimm

78 These findings have implications for genetic counseling and prenatal diagnosis for EBS.

79 arly diagnosis and treatment in newborns and genetic counseling and prenatal diagnosis in subsequent

80 These data have important implications for genetic counseling and prenatal diagnosis of HI, and als

81 This information can be elicited during genetic counseling and prior to genetic testing.

82 for precise clinical diagnosis, appropriate genetic counseling and proper medical management for aud

83 ature-sensitive TGM1 genotypes should aid in genetic counseling and provide insights into the pathoph

84 atients has implications for diagnostics and genetic counseling and provides a rational basis for the

85 Participants were offered free genetic counseling and rapid BRCA1/2 testing.

86 onable incidental genetic findings agreed to genetic counseling and screening.

87 nformation relevant to clinical genetics and genetic counseling and should yield insight into the gen

88 y for family members, including the need for genetic counseling and sometimes particular types of sur

89 We assessed the impact of genetic counseling and testing (GCT) on the use of endos

90 We examined patterns and correlates of genetic counseling and testing and the impact of results

91 historically have not sought or been offered genetic counseling and testing and thereby contribute to

92 ic cancer, where there are opportunities for genetic counseling and testing as well as clinical monit

93 (3) Genetic counseling and testing clarify the risk for reti

94 The availability of genetic counseling and testing could serve as a valuable

95 pants were 149 high-risk women who underwent genetic counseling and testing for alterations in the BR

96 pants were 289 high-risk women who underwent genetic counseling and testing for alterations in the BR

97 pants were 279 high-risk women who underwent genetic counseling and testing for alterations in the BR

98 Genetic counseling and testing for HNPCC significantly i

99 tection rates has important implications for genetic counseling and testing in clinical settings.

100 his study provides prospective evidence that genetic counseling and testing increased surveillance an

101 Cancer genetic counseling and testing is probably beneficial in

102 Genetic counseling and testing may aid in the management

103 Identified carriers were offered genetic counseling and testing of male partners.

104 gh frequency and wide spectrum of mutations, genetic counseling and testing with a multigene panel co

105 esearch on short-term effects of prevention, genetic counseling and testing, and screening activities

106 nvened including key stakeholders to address genetic counseling and testing, PCA screening, and manag

107 inations and imaging studies increased after genetic counseling and testing.

108 r intentions toward preventive surgery after genetic counseling and testing.

109 is to afford individuals access to anonymous genetic counseling and testing.

110 An exact molecular diagnosis allows genetic counseling and the identification of asymptomati

111 th positive screening results should receive genetic counseling and, if indicated after counseling, B

112 esity control rooted in studies of 1841, and genetic-counseling and cancer-survivorship studies.

113 cian to give better care, more sophisticated genetic counseling, and a more precise prognosis for the

114 rozygotes, which is essential for diagnosis, genetic counseling, and carrier prediction.

115 various medical specialties, social science, genetic counseling, and consumer advocacy.

116 test requisition forms and during post-test genetic counseling, and genetic ancestry predicted by a

117 STF reviewed the evidence on risk assessment,genetic counseling, and genetic testing for potentially

118 is with prognostic implications, has refined genetic counseling, and has formed the basis for prenata

119 lopment improves diagnostic capabilities and genetic counseling, and investigators can now turn to th

120 genes may improve premorbid risk assessment, genetic counseling, and management.

121 enotype may aid early diagnosis, appropriate genetic counseling, and monitoring for potential complic

122 Risk assessment, genetic counseling, and mutation testing did not cause a

123 ications for calculation of recurrence risk, genetic counseling, and potential treatment options, and

124 ype and can improve the clinical management, genetic counseling, and risk assessment of patients with

125 ime, making molecular diagnosis, prediction, genetic counseling, and risk management challenging.

126 5 gene will be useful for carrier detection, genetic counseling, and the identification of patients w

127 es has led to improved diagnosis, prognosis, genetic counseling, and, most importantly, new therapies

128 The implications of these results for genetic counseling are discussed.

129 vironment interaction, pharmacogenetics, and genetic counseling--are also discussed.

130 89 patients with ovarian cancer referred for genetic counseling at three institutions.

131 There are also important advances in genetic counseling based on results of early fetal diagn

132 scribed here have important implications for genetic counseling, because individuals with CADDS may p

133 , the more complex diagnosis, treatment, and genetic counseling become.

134 A woman who undergoes genetic counseling before testing can be told the probab

135 Each patient in the study underwent formal genetic counseling before testing.

136 Only 18.6 percent (33 of 177) received genetic counseling before the test, and only 16.9 percen

137 Genetic counseling both pretesting and posttesting is es

138 ocess, 82% of women wished to self-refer for genetic counseling, but 63% desired advice and recommend

139 riteria and respondents' report of receiving genetic counseling by a genetics clinician and its assoc

140 DECIPHER enhances genetic counseling by retrieving relevant information fr

141 In these families, genetic counseling can be difficult.

142 Genetic counseling can be effectively and efficiently de

143 ferral of high-risk patients and families to genetic counseling can greatly enhance the care of the p

144 s and prognoses, can improve the accuracy of genetic counseling, can reduce the risk of disease occur

145 Data analyzed were from six high-risk genetic counseling clinics and concern individuals from

146 h breast cancer seen at medical oncology and genetic counseling clinics in New York over a three and

147 As the definition of genetic counseling continues to evolve, so does the appl

148 as a genetic basis is important for accurate genetic counseling, early identification of individuals

149 Genetic counseling, education, and if chosen, genetic te

150 d P.J.W.) to achieve balance in the areas of genetics, counseling, ethics, and public policy, and to

151 We describe our genetic counseling experience with 2 large families pron

152 d up a new field for patient care, including genetic counseling for a severe disease, taking into acc

153 sociated with change in treatment and family genetic counseling for a small proportion of patients.

154 Laboratory diagnosis and genetic counseling for AS are complex, and mutation anal

155 These results support the importance of genetic counseling for both men and women with complex C

156 priate referral of African American women to genetic counseling for BRCA1/2 mutations.

157 Individuals referred to genetic counseling for cancer at two family cancer clini

158 cilitate discovery of this HSP gene, improve genetic counseling for families with linkage to this loc

159 gnosis based on genetic analysis can lead to genetic counseling for family members of patients.

160 hange in treatment for 14 patients (15%) and genetic counseling for future risk for 9 patients (10%).

161 Genetic counseling for IDC and FDC is also indicated to

162 ter program was more effective than standard genetic counseling for increasing knowledge of breast ca

163 and microarray analysis, to provide improved genetic counseling for phenotypic outcome in the prenata

164 These findings emphasize the importance of genetic counseling for prenatal carrier testing and may

165 A3-associated eye phenotypes can help inform genetic counseling for prognostic estimation of visual l

166 The approach to diagnosis and family genetic counseling for the dystrophinopathies is now wel

167 ther identified risk alleles, allows precise genetic counseling for the first time.

168 isorder has hindered clinical management and genetic counseling for the many affected individuals in

169 Genetic counseling for the one in 50 Ashkenazi Jewish in

170 This greatly changes psychiatric genetic counseling for these patients and families.

171 ause ALSP led to more accurate prognosis and genetic counseling for these patients in addition to inc

172 Issues in genetic counseling for this highly variable disease are

173 women but should be used as a supplement to genetic counseling for those at high risk.

174 Only 1334 (36.8%) reported receiving genetic counseling from a genetics clinician prior to te

175 l surgeon regarding appropriate patients for genetic counseling (GC) referral (approach 2).

176 Studies of risk assessment, genetic counseling, genetic testing, and interventions t

177 or younger should trigger consideration for genetic counseling/germline mutation testing and may ser

178 abnormalities, and will thereby improve the genetic counseling given to individuals with KITLG varia

179 This is important for genetic counseling: given that VWS is rare compared to n

180 r (82.5%) of 114 patients with ACC underwent genetic counseling (group 1).

181 nce useful to assist clinical ascertainment, genetic counseling, guidance of symptomatic monitoring,

182 data can provide accurate diagnoses, improve genetic counseling, help define disease mechanisms, esta

183 Physicians should be prepared to offer genetic counseling if they order genetic tests.

184 has important treatment (ketogenic diet) and genetic counseling implications.

185 ic disease, and a change in treatment beyond genetic counseling in 44%.

186 and facilitates the provision of appropriate genetic counseling in Alport syndrome.

187 Genetic counseling in EPP requires identification of FEC

188 Genetic counseling in families of isolated cases can sti

189 f the gene and raise important questions for genetic counseling in families with these distinctive ph

190 This finding is important to consider in SMA genetic counseling in individuals with black African anc

191 se penetrance estimates should be useful for genetic counseling in multiple-case families.

192 creening/early detection, and risk reduction/genetic counseling in their practices in the next 5 year

193 Genetic counseling increased the accuracy of risk percep

194 Education and genetic counseling increased understanding and retention

195 of HAE-C1-INH treatment in female patients, genetic counseling, infertility, abortion, lactation, me

196 as provided crucial information for accurate genetic counseling, inspired a recently proposed functio

197 icious genetic testing, pretest and posttest genetic counseling, interpretation and application of ge

198 The process of genetic counseling is critical both before and after tes

199 counseling before BRCA1/BRCA2 gene testing, genetic counseling is increasingly offered by telephone.

200 Genetic counseling is now routinely offered to individua

201 nts with defined autosomal dominant disease, genetic counseling is of high clinical relevance, also w

202 Genetic counseling is strongly advised for family member

203 A crucial issue in genetic counseling is the recognition of nonallelic gene

204 hildren of their daughters, raises important genetic counseling issues.

205 early and accurate diagnosis, and facilitate genetic counseling, leading to directly benefiting famil

206 sk individuals throughout families who, with genetic counseling, may become candidates for germ-line

207 ple guidelines emphasizing the importance of genetic counseling, most US women undergoing BRCA geneti

208 ific to key questions about risk assessment, genetic counseling, mutation testing, prevention interve

209 Standard one-on-one genetic counseling (n = 105) or education by a computer

210 education by a computer program followed by genetic counseling (n = 106).

211 assigned to in-person (n = 495) or telephone genetic counseling (n = 493).

212 s and will be valuable in the management and genetic counseling of a significant number of individual

213 ndings have important implications regarding genetic counseling of affected individuals who reach rep

214 offered free carrier screening, followed by genetic counseling of carriers, to all prenatal care pro

215 prognostic value and allows more insightful genetic counseling of couples who opt for assisted repro

216 upports better understanding, diagnosis, and genetic counseling of EV patients.

217 cant implications for medical management and genetic counseling of FA families.

218 d inheritance has important consequences for genetic counseling of families with Fanconi anemia belon

219 osaicism can have important implications for genetic counseling of families with hereditary disorders

220 The results have implications for genetic counseling of families with seemingly sporadic T

221 m in the FBN2 gene is important for accurate genetic counseling of families with sporadic cases of CC

222 HPE and demonstrate how this can inform the genetic counseling of families.

223 important for both analysis of patients and genetic counseling of families.

224 he phenotype, with profound implications for genetic counseling of individuals at risk for recurrence

225 The results are useful for genetic counseling of individuals with partial monosomy

226 ion from the location of mutations, will aid genetic counseling of individuals with TIGR/myocilin var

227 icism should always be considered during the genetic counseling of newly identified families with ret

228 assist physicians in prenatal diagnosis and genetic counseling of parents who are at risk for having

229 morigenesis, direct patient care, and enable genetic counseling of patients and families.

230 s and causes of HPE, and thus to improve the genetic counseling of patients and their families.

231 llele; this is of potential significance for genetic counseling of patients with EPP.

232 ave important public policy implications for genetic counseling of SCT carriers.

233 Genetic counseling of the affected families is an import

234 for patients with colorectal cancer and for genetic counseling of their relatives.

235 s should allow improved risk assessments for genetic counseling of women with premutation or intermed

236 In addition to their utility for improved genetics counseling of patients and their families, the

237 e of endocrine tumors increases, the role of genetic counseling on the multidisciplinary endocrinolog

238 tocols, range of clinical presentations, and genetic counseling options in the work-up of proximal mu

239 The USPSTF recommends against routine genetic counseling or BRCA testing for women whose famil

240 who received genetic testing did not receive genetic counseling or that the counseling was not effect

241 sociated significantly with participation in genetic counseling (OR = 5.46; 95% CI, 1.44 to 20.60; P

242 that can contribute to current screening and genetic counseling practices in a high-risk population.

243 ications for clinical practice, facilitating genetic counseling, prenatal diagnosis, and evaluation o

244 ation of heterozygous carriers, assisting in genetic counseling, prenatal testing, and preimplantatio

245 ety of different genes and investment in the genetic counseling process likely increases the chance t

246 Practical implications of these findings for genetic counseling, prognostication, and even therapy ha

247 and satisfaction among patients who receive genetic counseling provided by a genetics clinician, as

248 A large percentage of cancer genetic counseling providers predicted they would opt fo

249 xamination, review of systems, education and genetic counseling regarding Lynch syndrome (age 21 year

250 RC at age 35 years or younger should receive genetic counseling regardless of their family history an

251 ing African American women to participate in genetic counseling research for BRCA1 and BRCA2 (BRCA1/2

252 Any genetic-counseling service set up for families with deaf

253 Recently mandated coverage of genetic counseling services as a preventive service with

254 tinues to evolve, so does the application of genetic counseling services in all areas of medicine and

255 act on deaf people, in a population for whom genetic-counseling services are relevant.

256 or deafness mean that it is now possible for genetic-counseling services to offer genetic testing for

257 stories using the GREAT, separate from their genetic counseling session.

258 and IPAH patients but should be preceded by genetic counseling, since lifetime penetrance is only 10

259 This could be important in certain genetic counseling situations.

260 PCA in the multigene testing era addressing genetic counseling, testing, and genetically informed ma

261 rtant for identifying individuals to receive genetic counseling/testing (GC/GT).

262 Beyond diagnosis and genetic counseling, the benefits from studying these dis

263 hies will lead to more precise diagnosis and genetic counseling; therapeutic strategies are being dev

264 risk of etoposide is needed to provide sound genetic counseling to cancer patients treated with this

265 However, genetic counseling was more effective than the computer

266 tested whether telephone delivery of BRCA1/2 genetic counseling was noninferior to in-person delivery

267 g, whether informed consent was obtained and genetic counseling was offered before testing, and the i

268 explaining the origin, nature, and goals of genetic counseling, we consider the impact of the Human

269 r adjunct educational methods to traditional genetic counseling will be needed.

270 trial compared 1-year outcomes for telephone genetic counseling with in-person counseling among women

271 y," improves disease management, and fosters genetic counseling with respect to recurrence risks whil