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1 e inheritance of yeast prions (protein-based genetic elements).
2 a unique combination of pathogen and selfish genetic element.
3 ment and instead is a component of a selfish genetic element.
4 and determined their association with mobile genetic elements.
5 wide spectrum of viruses and other parasitic genetic elements.
6 erived from bacteriophages and other foreign genetic elements.
7 rsity, accumulation of mutations, and mobile genetic elements.
8 r memory of previous encounters with foreign genetic elements.
9 ovides RNA-mediated protection from invading genetic elements.
10 reness for the global dissemination of these genetic elements.
11 abroad for the dissemination of these mobile genetic elements.
12 r the discovery and functional annotation of genetic elements.
13 man genome that has been colonized by mobile genetic elements.
14 otect germ cells from the activity of mobile genetic elements.
15 n and are present on phages and other mobile genetic elements.
16 e of autonomously replicating foreign mobile genetic elements.
17 protect bacteria and archaea against foreign genetic elements.
18 as an adaptive immune system against foreign genetic elements.
19 genome stability and defence against foreign genetic elements.
20 rabilities that are capitalized on by mobile genetic elements.
21 protection against viruses and other mobile genetic elements.
22 romycetales, indicating that byps are mobile genetic elements.
23 e immunity against phages and other invading genetic elements.
24 nd by the high-order spatial organization of genetic elements.
25 , where they act as heritable, protein-based genetic elements.
26 rokaryotic defense mechanism against foreign genetic elements.
27 eletions to allow investigation of genes and genetic elements.
28 ing technology for studying the functions of genetic elements.
29 defends the germline genome against selfish genetic elements.
30 is a prokaryotic host defense system against genetic elements.
31 ge fraction of our genome consists of mobile genetic elements.
32 d by the ad hoc reuse of many types of basic genetic elements.
33 framework for quantifying the performance of genetic elements.
34 d archaea, and are often specified by mobile genetic elements.
35 systems protect prokaryotes against foreign genetic elements.
36 ptive immune system against extrachromosomal genetic elements.
37 ted in between the synthetically interacting genetic elements.
38 n shown to contain multiple different mobile genetic elements.
39 vectors; third, parallel origin from related genetic elements.
40 richia coli, its phages, plasmids and mobile genetic elements.
41 -cell genomes against the activity of mobile genetic elements.
42 that appear to have been derived from mobile genetic elements.
43 idered to be exceptionally successful mobile genetic elements.
44 ogenous retroviruses as well as other mobile genetic elements.
45 ARGs and their co-occurrence with associated genetic elements.
46 lysis of the 16S rRNA gene and various other genetic elements.
47 olerant DNA endonucleases that act as mobile genetic elements.
48 stem that protects prokaryotes from invading genetic elements.
49 by bacteria and archaea to fend off foreign genetic elements.
50 ae and suggest that they spread as parasitic genetic elements.
51 although SCCmec has been designated a mobile genetic element, a mechanism for its transfer has not be
53 mic conflict describes a phenomenon in which genetic elements act 'selfishly' to gain a transmission
54 e transcriptional network within which these genetic elements act to orchestrate hypertrophy gene exp
56 a general approach for creating context-free genetic elements and can be readily used in the bottom-u
57 ative traits are often propagated via mobile genetic elements and can be virulence factors from a bio
58 elements of VirB8-like proteins from mobile genetic elements and chromosomally encoded T4SS from G+
60 nds; evolutionary connections between mobile genetic elements and defense, whereby genes of mobile el
61 In addition to LuxR-LuxI, numerous other genetic elements and environmental conditions control bi
65 y-associated pandemics represented by mobile genetic elements and nonsynonymous mutations affecting a
66 s mediated by a diverse complement of mobile genetic elements and occurs primarily by conjugation or
68 t harmonious interactions between co-evolved genetic elements and result in reduced male fertility, s
69 rokaryotes against bacteriophages and mobile genetic elements and serve as the basis for revolutionar
71 e effect of the serial deletion of 5' and 3' genetic elements and sublethal doses of histone deacetyl
72 n, we isolated a set of NF-kappaB-activating genetic elements and tested their oncogenic potential in
74 Simple tandem repeats are highly variable genetic elements and widespread in genomes of many organ
75 d valuable data from microsatellites, mobile genetic elements, and accurate divergence time estimates
76 to the lytic origin of replication (OriLyt) genetic elements, and BET inhibitors prevent viral late
78 ction and subsequent degradation of invading genetic elements, and they have been classified into thr
79 rous; beta-lactamase genes carried on mobile genetic elements are a key mechanism for the rapid sprea
80 sting that the functional profiles of mobile genetic elements are associated with their environment,
82 es, but some homologs associated with mobile genetic elements are larger and contain an extra C-termi
85 e course of evolution, genomes acquire novel genetic elements as sources of functional and phenotypic
86 ermed YeastFab Assembly) to synthesize these genetic elements as standardized biological parts, which
87 and functional characterization of specific genetic elements associated with a phenotype of interest
88 inland China revealed the presence of mobile genetic elements associated with the expansion of emm12
89 gene transfer permits rapid dissemination of genetic elements between individuals in bacterial popula
91 iruses might descend from primordial selfish genetic elements, bona fide viruses evolved on multiple,
93 ed (Cas) systems detect and degrade invasive genetic elements by an RNA-guided, RNA-targeting multisu
96 ia and archaea acquire resistance to foreign genetic elements by integrating fragments of foreign DNA
97 hes, we have designed and introduced a novel genetic element called a ribo-attenuator in Bacteria.
100 on a single-celled ciliate reveal how mobile genetic elements can shape a genome, even one which is n
103 fit the guns-for-hire concept whereby mobile genetic elements capture host defense systems and repurp
104 Finally, we constructed a synthetic mobile genetic element carrying both the degradation pathway an
105 driven by horizontal dissemination of mobile genetic elements carrying blaKPC-2, followed by the intr
106 f pollutants, which can co-select for mobile genetic elements carrying multiple resistant genes.
107 tional multinational clinical trials for the genetic elements carrying pvl and 30 other virulence gen
113 m mutations or more importantly, from mobile genetic elements containing multiple resistance determin
114 l-spatial structure with diversity in mobile genetic element content, features that are useful for id
115 ates, are characterized by a distinct set of genetic elements controlling their gene expression.
116 oped an expression cassette architecture for genetic elements controlling transcription and translati
117 lso demonstrate that self-propagating active genetic elements (CopyCat elements) can efficiently dele
118 ease genes (HEGs), a class of simple selfish genetic elements, could be exploited for this purpose.
120 ngly influenced by the acquisition of mobile genetic elements encoding determinants involved in niche
121 of genomic DNA that contains all cis-acting genetic elements essential for accurate physiologic expr
122 es, and mobile elements, while these foreign genetic elements evolve diverse anti-CRISPR proteins to
126 ation of high-order barcoded combinations of genetic elements for high-throughput multiplexed charact
127 g strategy that generates fully exchangeable genetic elements for multigene engineering, the GB2.0 to
128 conjugative elements (ICEs) are self-mobile genetic elements found in the genomes of some bacteria.
130 n for the horizontal transfer of a "selfish" genetic element from cell to cell via membrane fusion.
137 called generalized transduction, some mobile genetic elements have developed elegant and sophisticate
138 , recombinases derived from unrelated mobile genetic elements have essential roles in both prokaryoti
142 ibit the replication of HIV and other mobile genetic elements.IMPORTANCE Piwil proteins inhibit the m
143 S albumin promoter is a promising endogenous genetic element in genetic engineering approaches requir
144 ame and can also be useful as a heterologous genetic element in other important oil seed crop plants
145 changes in BP, indicating that at least one genetic element in this refined region directly affects
146 ity of the mobilome (the total of all mobile genetic elements in a genome) between aquatic and terres
147 , suggesting a tumor-suppressor function for genetic elements in addition to DLEU2/miR-15a/16-1.
148 rsity of DNA sequences and multiple types of genetic elements in and near centromeres support centrom
151 s' highlights potential relevance of selfish genetic elements in facilitating lateral gene transfer i
152 ptive and heritable immunity against foreign genetic elements in most archaea and many bacteria.
157 rd genetic screen to systematically identify genetic elements in the HIV LTR promoter that modulate t
158 ht on the roles of these recently identified genetic elements in the mechanisms of host resistance an
161 d genetic drift acting on newly incorporated genetic elements in viral genomes, under conditions of e
163 of the evolutionary strategy of these mobile genetic elements, in addition to their carriage of impor
164 els of abundance of ARGs and those of mobile genetic elements (including integrons and plasmids), whi
165 nce are carried by plasmids and other mobile genetic elements, including bacteriophages and their rel
166 ons between genome structural variations and genetic elements, including chromosomal rearrangements,
167 form enables massively parallel detection of genetic elements, including gene transcripts and molecul
168 since its introduction by exchanging mobile genetic elements, including integrative conjugative elem
169 itochondria and other maternally transmitted genetic elements, including the role of cytonuclear inco
170 volutionarily connected to capsidless mobile genetic elements, including various plasmids and transpo
171 conjugative transposons) are modular mobile genetic elements integrated into a host genome and are p
172 construction is to manipulate viral proteins/genetic elements involved in antagonizing the host immun
173 n order to identify additional veA-dependent genetic elements involved in regulating ST production, w
174 ly within various host epithelial cells, the genetic elements involved in the HPT system in S. aureus
175 , widespread prion whose activity as selfish genetic element is counteracted by balancing selection f
177 In yeast, the cellular extrachromosomal genetic element [KIL-d] alters killer activity of M doub
178 us reservoirs in animals have provided novel genetic elements leading to the emergence of global pand
179 teraction of the host genes with surrounding genetic elements, like a convergently overlapped gene an
180 We conclude that these conserved functional genetic elements likely facilitated the repeated evoluti
181 titative behaviors for novel combinations of genetic elements limits the rational engineering of biol
185 ; and substantial bla KPC-associated, mobile genetic element (MGE) diversity (50% not within complete
187 ndergoing HDT through transmission of mobile genetic elements (MGEs) and genetic transformation.
188 e assembled genomic fragments include mobile genetic elements (MGEs) and metal resistance genes (MRGs
190 in resistance and virulence genes on mobile genetic elements (MGEs) between 40 isolates of methicill
192 ntibiotic-resistance genes (ARGs) and mobile genetic elements (MGEs) in farm environments can potenti
193 eptococcus thermophilus revealed that mobile genetic elements (MGEs) likely contributed to gene acqui
194 gulating the expression of genes from mobile genetic elements (MGEs), LexA often does so in concert w
199 lline cellulose efficiently and contains the genetic elements necessary for cellulosome production.
200 reatic cancer), a homing cassette, and other genetic elements needed for rapid insertion and conditio
201 Minimal bacterial gene set comprises the genetic elements needed for survival of engineered bacte
202 yploidy supports the acquisition of unstable genetic elements normally not seen in essential genes.
203 s do not interact directly but both occupy a genetic element of Gbx2, which is required for aortic ar
204 ilize AAV pseudotype vectors, containing the genetic elements of the canonical AAV2, packaged within
205 date mechanism through which the interacting genetic elements of the resistant Mcs5a allele modulate
207 arity between epigenetic factors, or between genetic elements on the basis of their epigenetic state,
208 lowed regulatory modulation through inserted genetic elements, on-demand control of the expression/tr
209 d study the epigenetic state of any class of genetic element or genomic region, we focus on two speci
210 ising resilience of this gene to addition of genetic elements or helix substitutions with phylogeneti
212 particular nucleotides or amino acids in the genetic elements or proteins, and is widely used in in v
213 he resulting fusions-supplied exogenously as genetic elements or purified protein fragments-had no si
214 jejuni ST-21 and ST-45 complexes identified genetic elements over-represented in clinical isolates t
217 e 5' chromosomal junction of a 45-kbp mobile genetic element, pLP45, which can exist as an episome or
218 gative elements (ICEs) are ubiquitous mobile genetic elements present as "genomic islands" within bac
219 n single nucleotide polymorphisms and mobile genetic element profiles, suggesting a single L. pneumop
220 CRISPR-Cas immunity against invasive mobile genetic elements, prokaryotes must first integrate fragm
221 r area of investigation is the assessment of genetic elements regulating tumor cell proliferation, es
222 odified DNA donor molecule acts as a selfish genetic element, replaces the targeted site and propagat
224 opagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mech
225 Analysing our data with exons as 'immobile genetic elements' revealed a similar frequency of unexpe
226 nown virulence factors, while several mobile genetic elements (SaPI5 and prophage SA3usa) were strong
227 gene, which is carried on a distinct mobile genetic element (SCCmec), the expression of which is con
228 resistance genes via the transfer of mobile genetic elements, selective pressure in vivo resulting i
229 defense and antibiotic selection for mobile genetic elements shapes in vitro E. faecalis populations
231 mode of germ-line transmission by a selfish genetic element signifies a mechanistic variation within
232 eritance phenomenon in which certain selfish genetic elements skew sexual transmission in their own f
234 lution to regulate genomic loci and to study genetic elements such as enhancers in biological process
236 antibiotic-resistant genes located on mobile genetic elements such as genomic islands, prophages, pat
237 cterial genome rearrangements involve mobile genetic elements such as insertion sequence (IS) element
239 curs through the uptake of DNA from invasive genetic elements such as plasmids and viruses, followed
241 e sequence-specific immunity against selfish genetic elements such as viruses and plasmids, by specif
242 ed parallels in other maternally transmitted genetic elements, such as bacterial endosymbionts of art
247 the pore-forming subunit, define the minimal genetic elements sufficient for metazoan and nonmetazoan
248 e domains that demarcate active and inactive genetic elements, suggesting that compartmentalization i
249 VRC01-class antibodies require few specific genetic elements, suggesting that naive-B cells with VRC
253 cus aureus pathogenicity islands (SaPIs) are genetic elements that are mobilized by specific helper p
255 b/Trithorax response elements (PRE/TREs) are genetic elements that can stably silence or activate gen
256 ntrol regions (ICRs), which are the discrete genetic elements that confer imprinted monoallelic expre
257 pread family of chromosomally located mobile genetic elements that contribute substantially to intra-
258 slands (PICIs) are a family of highly mobile genetic elements that contribute substantively to horizo
259 In this issue of Blood, Li et al reveal the genetic elements that control the activity of Bcl11b, a
260 lands are integrative and conjugative mobile genetic elements that convert nonsymbiotic rhizobia into
262 regulated by multiple positive and negative genetic elements that direct expression of genes require
266 at strain consists of two non-protein-coding genetic elements that must be located on the same chromo
267 ort tandem repeats (STRs) are highly mutable genetic elements that often reside in regulatory and cod
269 mids are stably maintained extra-chromosomal genetic elements that replicate independently from the h
274 ogram can be circumvented by a protein-based genetic element, the [GAR(+)] prion, permitting simultan
276 stem CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nucle
277 tentially allows for more complex and longer genetic elements to be packaged into an AAV vector inclu
278 e, reflects the ability of the corresponding genetic elements to maintain mobility and persistence in
280 t our method links plasmids and other mobile genetic elements to their host species in a real microbi
281 meiosis provides an opportunity for selfish genetic elements to violate Mendel's law of segregation
282 evolutionarily conserved function in mobile genetic element (transposons) silencing and maintenance
284 ults of this study provide insights into the genetic elements underlying seed-size variation in maize
285 ormation by Ure2p produces the non-Mendelian genetic element [URE3] in Saccharomyces cerevisiae, maki
288 uide strands derived from invading or mobile genetic elements, via an unknown pathway, to direct guid
291 Bacterial toxin-antitoxin (TA) systems are genetic elements, which are encoded by plasmid as well a
292 ported transmission of resistance via mobile genetic elements, which demonstrated greater diversity o
293 Flavin mononucleotide (FMN) riboswitches are genetic elements, which in many bacteria control genes r
294 sequence provides a thorough catalog of the genetic elements whose altered dosage perturbs developme
296 g biology now depends on the ad hoc reuse of genetic elements whose precise activities vary across ch
298 lds identified ARGs likely located on mobile genetic elements, with up to 11 ARGs per plasmid-associa
299 and RA in B6.C3-Bbaa1 mice, formally linking genetic elements within Bbaa1 to pathological production
300 mal rap-phr genes are also present on mobile genetic elements, yet relatively little is known about t
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