ライフサイエンスコーパス: genetic factor

1 ht occipital part (correlation was driven by genetic factors).

2 phropathy, calcineurin inhibitors (CNI), and genetic factors.

3 nd mouths of faces-is strongly influenced by genetic factors.

4 cariogenic taxa are likely not controlled by genetic factors.

5 ood asthma is inconsistent and may depend on genetic factors.

6 denocarcinoma (EAC) based on genetic and non-genetic factors.

7 l's risk of disease based on genetic and non-genetic factors.

8 (S-HSCR), which has not been associated with genetic factors.

9 ess vulnerability is not solely indicated by genetic factors.

10 ction and treatment depend on viral and host genetic factors.

11 ich are influenced by both environmental and genetic factors.

12 e a combination of environmental, stress and genetic factors.

13 ria susceptibility is determined by multiple genetic factors.

14 ntal outcomes fail to account for underlying genetic factors.

15 to drugs is strongly determined by multiple genetic factors.

16 at these phenotypes are mainly controlled by genetic factors.

17 astrocytes through the expression of defined genetic factors.

18 etween accessions in relation to climate and genetic factors.

19 mplex interactions between environmental and genetic factors.

20 which is not fully explained by hormonal or genetic factors.

21 emic exposure, suggesting the involvement of genetic factors.

22 ial complication involving environmental and genetic factors.

23 We used gene targeting to validate candidate genetic factors.

24 r of the influence of both environmental and genetic factors.

25 conferred by lifestyle may be diminished by genetic factors.

26 that may be enriched with disease-protective genetic factors.

27 e traits, and whether such sharing is due to genetic factors.

28 nced by disease severity, environmental, and genetic factors.

29 children share a large proportion of common genetic factors.

30 gender, socioeconomic status, culture) than genetic factors.

31 ed to a sedentary lifestyle, overeating, and genetic factors.

32 ical, lipid, and cardiovascular traits share genetic factors.

33 red lifestyle, anthropometric, and inherited genetic factors.

34 es, underscoring the existence of additional genetic factors.

35 difference may be due, at least in part, to genetic factors.

36 s for CHD and other diseases associated with genetic factors.

37 ontribute less to the development of AS than genetic factors.

38 r-individual variance in HCC have implicated genetic factors.

39 al variation is only partly accounted for by genetic factors.

40 tation, which can be partially attributed to genetic factors.

41 ts, memory reconsolidation, epigenetics, and genetic factors.

42 re, quality and access, or environmental and genetic factors.

43 rdiomyopathy phenotype and are controlled by genetic factors.

44 relation the majority (78%) was explained by genetic factors.

45 stance use (r = 0.2), which was explained by genetic factors (59%) and unique environmental factors (

46 In addition, shared genetic factors account for some phenotypic correlations

47 bination, different weights of exogenous and genetic factors account for the wide disease spectrum th

48 Variance decomposition showed that additive genetic factors accounted for 68% (95% CI, 60%-75%) of t

49 These findings provide insights into the genetic factors accounting for inherited squamous cell c

50 , use the internet for information about how genetic factors affect CHD risk (OR, 2.11 [CI, 1.03-4.47

51 RATIONALE: How host genetic factors affect Mycobacterium tuberculosis (Mtb)

52 Both ecological and genetic factors affected plasmid distribution: plasmid p

53 tlantic herring facilitates the detection of genetic factors affecting adaptation because of the shar

54 ry, suggesting that there might be different genetic factors affecting susceptibility across ancestry

55 llenging and population-specific, but use of genetic factors along with a few common population-relev

56 The interplay among genetic factors, alterations in neurotransmitters, elect

57 ry-early-onset IBD not associated with known genetic factors analyzed in Toronto, Oxford, and Munich.

58 l and lung cancers and suggests that certain genetic factors and biological pathways affecting adult

59 We found clear subtype heterogeneity for genetic factors and breastfeeding.

60 A statistical model including additive genetic factors and environmental factors partly shared

61 ease (IBD) involves interaction between host genetic factors and environmental triggers.

62 In any particular environment, diet, genetic factors and human influences can shape the bacte

63 Genetic factors and mechanisms underlying food allergy a

64 g the relationship between environmental and genetic factors and metabolic fluxes hidden in existing

65 feature-and-network-based prioritization of genetic factors and molecular mechanisms.

66 mpal volume and AD is the result of multiple genetic factors and not exclusively variability in the A

67 unities are more strongly influenced by host genetic factors and plant breeding than bacterial commun

68 ronary artery ectasia (CAE) is influenced by genetic factors and related to the presence of aneurysms

69 s a complex trait and controlled by multiple genetic factors and sex, and that the CC population can

70 We sought to test the contribution of genetic factors and shared and unique environment to ris

71 in and MDD and estimated the contribution of genetic factors and shared environment in GS:SFHS.

72 Maternal diabetes, genetic factors and some teratogens have been shown to b

73 e self-administration model is controlled by genetic factors and that the role of social learning is

74 aper investigates the relative importance of genetic factors and the common environment between twins

75 This can provide a link between individual genetic factors and the mechanistic underpinnings of SCZ

76 Risk models with various combinations of non-genetic factors and the PRS were compared for their accu

77 er, systematic approaches for addressing how genetic factors and their regulators determine variation

78 of cancers and other diseases underpinned by genetic factors, and exploring new therapeutic opportuni

79 cy is common, correctable, and influenced by genetic factors, and it has been associated with risk of

80 Environmental exposures, genetic factors, and structural pulmonary risk factors p

81 ure extrauterine environment is modulated by genetic factors, and that PPARG signaling has a previous

82 Genetic factors are associated with susceptibility to ma

83 Genetic factors are clearly important in the development

84 Both social environment and genetic factors are critical for smoking initiation and

85 social and other environmental factors, but genetic factors are estimated to account for at least 20

86 iated with variation in alcohol consumption, genetic factors are estimated to explain about half of t

87 ed significant heritability, indicating that genetic factors are important, determining up to 85% of

88 e and has a complex pathophysiology in which genetic factors are important.

89 by environmental factors and habits and that genetic factors are moderately involved in the regulatio

90 Genetic factors are surprisingly relevant: PTSD has been

91 Because no evidence could be obtained that genetic factors are the reason for the association betwe

92 ethal and heritable; however, the underlying genetic factors are unknown.

93 ing evidence that environmental, rather than genetic, factors are the major causes of most chronic di

94 Genetic factors, as well as chronic pain in a partner or

95 s in BRCA2 as the most common high-penetrant genetic factor associated with pancreatic cancer and we

96 IM22-NOD2 network and signaling pathways and genetic factors associated very early onset and adult-on

97 etic factors associated with risk of SCZ and genetic factors associated with AFB.

98 will help in the better understanding of the genetic factors associated with altered glycosylation an

99 The number of genetic factors associated with asthma remains limited.

100 To identify genetic factors associated with childhood ALL risk in th

101 Studies of the genetic factors associated with human autoimmune disease

102 eal examples: an analysis of genetic and non-genetic factors associated with human longevity from a f

103 The identification of genetic factors associated with kidney disease has the p

104 ldren designed to understand immunologic and genetic factors associated with neurocognitive deficits

105 Our data provides first evidence that the genetic factors associated with pigmentation traits are

106 We sought to identify genetic factors associated with plasma betaine levels an

107 We investigated host genetic factors associated with protection against CD4(+

108 s evidence for a significant overlap between genetic factors associated with risk of SCZ and genetic

109 tion and transmission, and explored distinct genetic factors associated with the emergence of the Eas

110 We show that genetic factors associated with timing of reproduction a

111 ility is widely believed to be influenced by genetic factors, but no study has reported a genetic var

112 nt viral load attributable to viral or human genetic factors by using joint host/pathogen genetic dat

113 ption of sugar-containing drinks and whether genetic factors can explain the association with substan

114 ales and females are generally determined by genetic factors carried by sex chromosomes.

115 as being associated with genetic and/or non-genetic factors (clone and passage), and we found that a

116 Genetic factors contribute importantly to the risk of co

117 ase (CAD) is the leading cause of death, and genetic factors contribute significantly to risk of CAD.

118 These novel findings indicate shared genetic factors contribute significantly to the covarian

119 Although genetic factors contribute substantially to CAD risk, at

120 Although genetic factors contribute to almost half of all cases o

121 Environmental and genetic factors contribute to disease susceptibility, wh

122 Although genetic factors contribute to interindividual and interp

123 Both environmental and genetic factors contribute to schizophrenia; however, th

124 We analyzed whether and how genetic factors contribute to sex-specific predispositio

125 Despite evidence that genetic factors contribute to the duration of gestation

126 Although environmental and genetic factors contribute to the etiology of alcohol us

127 ed with obesity and type-2 diabetes, but how genetic factors contribute to variable sugar preferences

128 To identify genetic factors contributing to amyotrophic lateral scle

129 Although numerous genetic factors contributing to autoimmunity have been i

130 We identified genetic factors contributing to individual differences i

131 vessel occlusion (SVO)-to identify potential genetic factors contributing to ischemic stroke.

132 tify specific CAD risk alleles and potential genetic factors contributing to the comorbidity of CAD w

133 Taken together, we have identified genetic factors contributing to variation in caffeine me

134 Little is known about the genetic factors controlling tree size and shape.

135 A combination of environmental and genetic factors determines when seed germination occurs.

136 zygotic, 49% dizygotic), we demonstrate that genetic factors do indeed contribute strongly to eye mov

137 depends on tDCS intensity, and task relevant genetic factors (e.g., for WM: COMT val(158)met, DAT, BD

138 Non-genetic and genetic factors each account for approximately 10% of th

139 oring system, which encompasses familial and genetic factors, ECG abnormalities, arrhythmias, and str

140 inability to quit smoking are influenced by genetic factors, emphasizing the importance of understan

141 r hypertension, supporting the proposal that genetic factors enhance FSGS susceptibility.

142 ed in the etiopathogenesis of ASD, including genetic factors, environmental toxins and stressors, imp

143 Genetic factors explained 35% of the variation in progre

144 Overall, additive genetic factors explained 36% (95% confidence interval [

145 Genetic factors explained 48% of the variation in high s

146 combined results suggest that BxPrx is a key genetic factor facilitating the infestation and distribu

147 win analyses support the existence of common genetic factors for addiction in general.

148 on, however, are poorly described and common genetic factors for alcohol and nicotine remain unidenti

149 e, and the molecular and functional basis of genetic factors for hybrid male sterility is of great in

150 n studies (GWAS) have effectively identified genetic factors for many diseases.

151 To date, this is the only genetic factor found to moderate downstream effects of a

152 uantitative trait loci (eQTLs) revealed that genetic factors had a stronger effect on immune gene reg

153 on, although interest in the contribution of genetic factors has been fueled by detection of somatic

154 ase (IBD), identifying the function of these genetic factors has proved challenging.

155 r neutropenia, are largely unknown, although genetic factors have an important role.

156 Although several genetic factors have been found to cause late-onset hemo

157 A plethora of genetic factors have been identified that drive the dege

158 Genetic factors have been shown to play an important rol

159 the phenotypic variance of AF was 19.9% for genetic factors (heritability), 3.5% for shared environm

160 sitive affect is substantially influenced by genetic factors; however, our understanding of genetic p

161 aim of this study was to identify additional genetic factors (i.e., "second hits") that may contribut

162 Genetic factors impact behavioral traits relevant to num

163 re studies can explore the identity of these genetic factors, improving our understanding of how they

164 ely, there was no evidence to support shared genetic factors in AD and IS overall, or with the other

165 added sugar, has been shown to interact with genetic factors in affecting CAD risk factors such as ob

166 genic inheritance implies a role for several genetic factors in disease etiology.

167 ologic evidence supporting the importance of genetic factors in influencing obstructive sleep apnea,

168 evidence strongly supports a role for other genetic factors in modifying the disease pathogenesis dr

169 Second, it dismisses the role of genetic factors in shaping criminal propensities across

170 ogical framework encapsulating cognitive and genetic factors in the development of both psychopatholo

171 Given the central role of genetic factors in the pathogenesis of common neurodegen

172 However, the role of genetic factors in this relationship has not been invest

173 Genetic factors increase risk for progressive NAFLD.

174 ut microbiota structure by environmental and genetic factors increases the risk of pathogen infection

175 Genetic factors influence both occurrence and severity o

176 The data indicate that host genetic factors influence fungal growth strategy with an

177 However, whether genetic factors influence gaze to complex visual scenes

178 uman superior frontal cortex, that heritable genetic factors influence SERPING1 gene expression level

179 A controversial hypothesis is that genetic factors influence vulnerability to depression fo

180 Genetic factors influenced a significant and substantial

181 ata provide further evidence for the role of genetic factors influencing diabetic kidney disease in t

182 architecture: (i) Has assortment on measured genetic factors influencing reproductive and social fitn

183 -disorder links reflect the heterogeneity of genetic factors influencing social communication difficu

184 Our study expands the understanding of genetic factors influencing the size of the retinal micr

185 otics outside of the health care sector, and genetic factors intrinsic to bacteria.

186 Here, we aimed to determine the genetic factors involved in generating the helical shape

187 ntified neural circuits, neuromodulators and genetic factors involved in social behaviors, but mechan

188 To identify genetic factors involved in the regulation of NK cell fu

189 ubcategorizing the phenotypes and underlying genetic factors involved.

190 could be modeled in animals wherein a single genetic factor is altered, our work provides a biologica

191 aits and diseases, assessing the risk due to genetic factors is challenging because it requires knowl

192 This study highlights that a genetic factor known to be associated with constitutive

193 tic effects of TEs and higher levels of host genetic factors known to promote epigenetic silencing.

194 ecause of a combination of environmental and genetic factors leading to activation of oncogenes or in

195 Genetic factors likely contribute to the observed ethnic

196 Maternal and inherited (ie, case) genetic factors likely contribute to the pathogenesis of

197 pitopes and further influenced by additional genetic factors, likely to be MHC II.

198 Pathogen genetic factors linked to this increase need assessment.

199 Genetic factors make less of a contribution in this coho

200 etiology of MT have been postulated, such as genetic factors, masticatory hyperfunction, trauma, and

201 Finally, recent data suggest that host genetic factors may also modulate the severity of P. aer

202 Genetic factors may also play an important role in confe

203 findings suggest that biologically plausible genetic factors may alter susceptibility to PM10-associa

204 nce components analyses, and that the common genetic factors may influence beta-carotene and obesity

205 dentifies critical sensitive periods whereby genetic factors may influence risk for psychiatric disea

206 Genetic factors may play a greater role in average 25(OH

207 Although genetic factors may play a part, the rapidity with which

208 y a subset of patients, suggesting that host genetic factors may play a role.

209 Although recent observations suggest that genetic factors may play a significant role in diverticu

210 sought to evaluate the hypothesis that human genetic factors may underlie AVM in previously healthy c

211 shed data from 2 Danish cohorts suggest that genetic factors may underlie some of this variability.

212 Genetic factors modifying the blood metabolome have been

213 genetic effects of euchromatic TEs, and host genetic factors modulating such effects, play a critical

214 uld lead to irritable bowel syndrome include genetic factors (most notably an identified mutation of

215 Few robust genetic factors of PTB have been identified.

216 known about the impact of environmental and genetic factors on brain asymmetry development.

217 ion of molecular mechanisms and functions of genetic factors on diseases.

218 The influence of parasite genetic factors on immune responses and development of s

219 and evaluated the influence of clinical and genetic factors on renal survival.

220 Importantly, genetic factors operating at 8 years explained only appr

221 oked by additional environmental/acquired or genetic factors, or both.

222 Genetic factors, particularly those with environmental i

223 By contrast, genetic factors play a major role in both the presence a

224 Genetic factors play a major role in the etiology of epi

225 Whether genetic factors play a role in speech encoding at the su

226 Genetic factors play an important role in hearing loss,

227 a multi-factorial blinding disease in which genetic factors play an important role.

228 Genetic factors predispose individuals to attention-defi

229 a cohort of 134 probands with TD to identify genetic factors predisposing to the disease.

230 ls in the highest quartile of risk, based on genetic factors (PRS), had a 2-fold higher risk of BE (o

231 d both cortically and subcortically, yet the genetic factors regulating this modulation regarding spe

232 usbands and wives carry similar loadings for genetic factors related to education and height.

233 to assess behavioral, sociodemographic, and genetic factors related to ICS response among African Am

234 populations, but the nature of the involved genetic factors remains unknown.

235 Environmental and genetic factors represent key components in the establis

236 ting that there is an optimal combination of genetic factors required for survival, virulence and tra

237 The genetic factors responsible for the variations (or quant

238 the PRSs in the model developed based on non-genetic factors resulted in a net reclassification impro

239 ent is controlled, an appreciable extent, by genetic factors segregating in the Collaborative cross p

240 treatment before admission, and for a known genetic factor, sEPCR level at admission was positively

241 Genetic factors, sex, and ethnicity should be considered

242 Connectome genetics seeks to uncover how genetic factors shape brain functional connectivity; how

243 In this study, we examined whether genetic factors shape systemic immune responses in patie

244 monstrates that dusp6 deficiency is a strong genetic factor shaping gut microbiota, and that it confe

245 oach does not leverage the environmental and genetic factors shared among the multiple phenotypes col

246 se phenotypic correlations were explained by genetic factors shared between each disorder, substance

247 n, thus accounting for all environmental and genetic factors shared by siblings, labor induction was

248 After taking account of these confounds, genetic factors significantly contribute to spindle and

249 Genetic factors significantly influence susceptibility f

250 as 80%, a large proportion of the underlying genetic factors still remain to be elucidated.

251 r the past decade, suggesting a role for non-genetic factors such as epigenetic mechanisms in disease

252 lopment is regulated by a complex balance of genetic factors, such as FVIII genotype, and environment

253 Genetic factors, such as rare variants in the microglial

254 contribution of environmental compared with genetic factors that affect variations in immune traits

255 is needed to determine the environmental and genetic factors that cause these neurological symptoms.

256 Recent studies have identified genetic factors that confer an increased risk of SZ and

257 re investigations into the environmental and genetic factors that confer risk of ASD.

258 g susceptibility to disease, but most of the genetic factors that contribute to disease susceptibilit

259 e recently gained unprecedented insight into genetic factors that determine risk for Barrett's esopha

260 Further, human genetic factors that facilitate these anti-atherogenic p

261 Genetic factors that have been identified include genes

262 In addition, we summarize the genetic factors that have provided insight into the mech

263 transcriptional coregulatory modules and the genetic factors that impact miRNA function.

264 Common genetic factors that influence the co-occurrence of MDD

265 udy was to increase our understanding of the genetic factors that mediate retinal vessel size.

266 le-exome sequence (WES) analysis to identify genetic factors that might cause granulomatous colitis a

267 netic studies have not attempted to identify genetic factors that predict relapse risk (the primary e

268 red to have a strong association with NAFLD, genetic factors that predispose liver to NAFLD and molec

269 s of diversification, but the ecological and genetic factors that promote these radiations are still

270 A causative understanding of genetic factors that regulate glioblastoma pathogenesis

271 s is conferred by multiple environmental and genetic factors, the findings related to FKBP5 illustrat

272 ry factors and lifestyle, environmental, and genetic factors; thus, men who exclude some or all anima

273 study sought to clarify the contribution of genetic factors to EoE through estimation of familial ag

274 the challenge is to winnow out the unrelated genetic factors to identify those related specifically t

275 re we determine the relative contribution of genetic factors to individual variation in the shape of

276 opaminergic modulation, and the potential of genetic factors to stratify patients.

277 s, and to our knowledge, the contribution of genetic factors to this relation has not previously been

278 This study indicates that multiple genetic factors underlie the risk of lung adenocarcinoma

279 We identified Cyfip2 as a major significant genetic factor underlying binge eating and provide a beh

280 We validated Cyfip2 as a major genetic factor underlying binge eating in heterozygous k

281 The genetic factors underlying basal WBC traits in Hispanics

282 Understanding the genetic factors underlying neurodevelopmental and neurop

283 Studying the genetic factors underlying relative performance between

284 sites, and over time, with identification of genetic factors underlying the epidemiological success o

285 Here we investigate genetic factors underlying the risk of this disease by c

286 but despite widespread efforts, the specific genetic factors underlying these disorders remain undefi

287 We investigated the evidence that shared genetic factors underpin the two diseases.

288 No genetic factor was associated with patient survival, acu

289 One genetic factor was common to Social Communication Disord

290 Genetic factors were also of influence, suggesting that

291 ial factors, while for asthma, pollution and genetic factors were often investigated in systematic re

292 large -cohort datasets, we demonstrated that genetic factors were the major contributor to the negati

293 Syndrome, but our understanding of the HSA21 genetic factors which contribute to fetal brain developm

294 x, environmental factors (such as diet), and genetic factors, which vary widely among different parts

295 anscription factor ATHB5 was identified as a genetic factor whose localized expression promotes GA-me

296 bivariate GWAS meta-analysis to demonstrate genetic factors with pleiotropic effects on bone mineral

297 Press journals, integrate environmental and genetic factors with the direction and magnitude of immu

298 e insights into the interplay among multiple genetic factors, with applications including assessment

299 ual eye movements, is strongly influenced by genetic factors, with effects directly traceable to the

300 vironmental conditions and mosquito/parasite genetic factors, with minimal contribution from mosquito