ライフサイエンスコーパス: genetic locus

1 on mutant and VTC4-1 are alleles of the same genetic locus.

2 (HXGPRT) of the parasite encoded by a single genetic locus.

3 expression within a single cell at a single genetic locus.

4 TR of TTP mRNA was deleted in the endogenous genetic locus.

5 es with a tumor suppressor, namely the INK4a genetic locus.

6 be confirmed by a test targeting a different genetic locus.

7 sults for mammals are sensitive to choice of genetic locus.

8 hich is known to be associated with the H-2D genetic locus.

9 d in a cluster of genes that occupy a common genetic locus.

10 lies the difficulty in matching the QTL to a genetic locus.

11 logs and are similarly derived from the same genetic locus.

12 of normal and mutant individuals for a given genetic locus.

13 ing to copper (copR), and an uncharacterized genetic locus.

14 ntify a new gene corresponding to the lin-10 genetic locus.

15 at onset, are at least in part determined by genetic locus.

16 phenotypes were due to mutation at the same genetic locus.

17 howed microsatellite instability in a single genetic locus.

18 ng alleles potentially from any heterozygous genetic locus.

19 method for identifying QTLs at the level of genetic locus.

20 cifically defined mutations in more than one genetic locus.

21 trains were recessive and mapped to the same genetic locus.

22 latency determinant encoded within the same genetic locus.

23 umbers of subunits all derived from the same genetic locus.

24 to hard or soft selective sweeps at a single genetic locus.

25 due to somatic alterations of the INK4A/ARF genetic locus.

26 (LD) among SNPs, we view each LD block as a genetic locus.

27 of the two roles is determined by a separate genetic locus.

28 mologous recombination into the murine mdr1a genetic locus.

29 re homozygous at an immunologically relevant genetic locus.

30 (FISH) testing for the amplification of the genetic locus 19q13.42 involving the C19MC cluster of mi

31 roteomic analysis, and NMR, we show that the genetic locus affects the regulation of quorum sensing a

32 dependent of the Toll-like receptor 4 (tlr4) genetic locus and allelic major histocompatibility compl

33 ese tumors, we have characterized the hRad51 genetic locus and mapped it to chromosome 15q14-15 withi

34 on between DNA sequence variants at the TGFA genetic locus and nonsyndromic oral clefts, 47 studies h

35 sgene were rendered congenic for the Sle1(z) genetic locus and phenotyped for serologic, cellular, an

36 t mechanism for the association between this genetic locus and susceptibility to CAD.

37 rd and Tcra gene segments reside in a single genetic locus and undergo recombination in CD4- CD8- (do

38 ay not represent a single variable site at a genetic locus, and (3) linkage disequilibrium can be use

39 racting species in a community, alleles at a genetic locus, and companies in a market are characteriz

40 he full spectrum of genetic risk in the PLB1 genetic locus are warranted.

41 Here we report a genetic locus associated with a human syndrome of coexis

42 To our knowledge, this is the first genetic locus associated with both cancer risk and WHR.

43 Our results identify a genetic locus associated with estrogen receptor negative

44 A new genetic locus associated with Mycoplasma pneumoniae cyta

45 kinase (DMPK) is the protein product of the genetic locus associated with myotonic dystrophy, in whi

46 This report describes a genetic locus associated with siderophore biosynthesis a

47 ports growth of C. jejuni and identified the genetic locus associated with the utilization of this su

48 e-wide association studies have identified a genetic locus at human chromosome 8q24 as having minor a

49 Thus, we have identified a genetic locus at or near the LPL gene locus which contri

50 lations from Hawaii and Pennsylvania share a genetic locus at which a recessive mutation associated w

51 the need to perform different PCRs for each genetic locus being studied in an ancient DNA extract.

52 gene segments are organized within a single genetic locus but are differentially regulated during T

53 d MGC29643 transcripts derived from the same genetic locus but transcribed in opposite directions.

54 scriminating power of HRM + SVM for a single genetic locus by testing longer amplicons harboring sign

55 ected individuals has suggested that a major genetic locus can account for the disorder in some famil

56 sults show that even a single nonrecombining genetic locus can provide substantial power to test the

57 Both of these defects were due to a single genetic locus carrying a Tn5 insertion.

58 e response regulators encoded within its own genetic locus (CheY(1), CheY(2), and CheY(5)) and CheY(3

59 F receptor null mutant mice, we discovered a genetic locus, closely linked to the TNF p55 receptor (T

60 rons and was localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cance

61 ancy because biallelic mutations at a single genetic locus confer all features that define cancer upo

62 tokine encoded in a functionally polymorphic genetic locus, contributes to detrimental inflammation b

63 red mouse strains demonstrated that a single genetic locus controlled responsiveness to LPS.

64 lic to aconidiate-2, a previously identified genetic locus controlling conidiation.

65 lE) represent the 3' end of a newly reported genetic locus (cyl) required for GBS haemolysin/cytolysi

66 S3007 and within a 17-cM region flanking the genetic locus D4S2366.

67 eins and that mutations at the corresponding genetic locus daf-5 confer defects in DAF-7/TGF-beta sig

68 S886 and D19S894, and have established a new genetic locus designated SCA26.

69 of this paper is to report the linkage of a genetic locus (designated "HBM") in the human genome to

70 a signal sequence led to the discovery of a genetic locus, designated 2.9, which appears to be prese

71 These data functionally define a novel genetic locus, designated PAC1, for prostate adenocarcin

72 of high-reticuline poppy mutants revealed a genetic locus, designated STORR [(S)- to (R)-reticuline]

73 Subcloning and mutagenesis defined a genetic locus, designated zmaR, on a 1.2-kb fragment of

74 nge of mapped and anchored object types with genetic locus details, such as numbers, types and names

75 Our findings indicate that a single genetic locus determines host specificity in this bacter

76 encoding gene couch potato (cpo) as a major genetic locus determining diapause phenotype in D. melan

77 We previously identified a genetic locus, Diet1, which is responsible for the resis

78 a dominantly acting mutation that disrupts a genetic locus distinct from the ADPKD loci, PKD1 and PKD

79 genome, including information by isotype and genetic locus, easily downloadable primary sequences, gr

80 Of particular interest was genetic locus EF1809, predicted to encode a regulatory p

81 nt this problem, we have chosen to clone the genetic locus encoding a mammalian GDP-D-mannose-4,6-deh

82 sis and a screen for loss of cytotoxicity, a genetic locus encoding an RTX toxin system was identifie

83 re is directed by the specific sequence of a genetic locus encoding enzymes directing one of four alt

84 We propose a likely genetic locus encoding synthesis of the anionic polymer

85 at homozygous deletion involving CDKN2A (the genetic locus encoding the cyclin-dependent kinase inhib

86 an independent discovery and extension of a genetic locus encoding the GBS beta-haemolysin/cytolysin

87 By deleting the genetic locus encoding the regulatory B1 subunit of calc

88 train DH5 alpha with plasmids containing the genetic locus encoding this protein gave rise to E. coli

89 eripherin as orthologs (products of the same genetic locus, evolving separately only since the specie

90 strains contain copies of losA and losB in a genetic locus flanked by infA and ksgA.

91 A genetic locus for a cytolethal distending toxin (CDT) wa

92 autosomal recessive trait and define a novel genetic locus for AF on chromosome 5p13 (arAF1).

93 We sought to identify the genetic locus for an inherited form of dilated cardiomyo

94 verse K277R mutation, establishing RT as the genetic locus for aptamer-mediated HIV-1 inhibition.

95 viduals demonstrates that there is no single genetic locus for AR-DC.

96 The most significantly associated genetic locus for atrial fibrillation (AF) is in chromos

97 We identified a genetic locus for autosomal-recessive nonsyndromic intel

98 overlaps the critical region for the fourth genetic locus for Bardet-Biedl syndrome (BBS4) in humans

99 n chromosome 12p11.2, which falls within the genetic locus for congenital fibrosis of the extraocular

100 ally regarded as a heritable disorder, yet a genetic locus for familial AF was previously mapped to c

101 A genetic locus for FJP has not yet been identified by lin

102 ember subset of this family to determine the genetic locus for HP.

103 The genetic locus for HSAN I has been mapped to chromosome 9

104 RS when it occurs in isolation, and only one genetic locus for isolated DRS, the DURS2 locus on chrom

105 The refinement of the genetic locus for multiple cutaneous and uterine leiomyo

106 is family is linked to the recently reported genetic locus for multiple cutaneous and uterine leiomyo

107 to refine substantially the location of the genetic locus for multiple cutaneous and uterine leiomyo

108 A genetic locus for mutations associated with dilated card

109 In previous efforts to identify the genetic locus for prcd, the canine homologs for many of

110 a highly heritable trait, identifies a novel genetic locus for RLS, and will facilitate further cloni

111 Our observations suggest that there is a genetic locus for social cognition, which is imprinted a

112 We have studied INS VNTR as a candidate genetic locus for susceptibility to PCOS.

113 The genetic locus for SVD lies in a 9 Mb region flanked by D

114 A genome-wide scan previously localized the genetic locus for SVD to a 20 Mb region flanked by D2S21

115 Previously we mapped the genetic locus for the triad of autosomal recessive ARVC,

116 The genetic locus for the TrkC/neurotrophin 3 (NT-3) recepto

117 The genetic locus for this retinal dystrophy has been mapped

118 ouse macrophages, which are deficient in the genetic locus for TLR4, was absent.

119 Among Hispanics, we identified a genetic locus for upper-lower lobe ratio near the alpha-

120 The genetic locus for Vi antigen production is also present

121 In humans, DCX is a major genetic locus for X-linked lissencephaly.

122 A genetic locus from Campylobacter jejuni 81-176 (O:23, 36

123 that allow for the transposition of a single genetic locus from one position on a chromosome to anoth

124 llowed the identification of a newly defined genetic locus, fxsA.

125 We report identification of a novel genetic locus (GLC1P) for normal tension glaucoma (NTG)

126 s the first genome-scan report to identify a genetic locus harboring a gout-susceptibility gene.

127 To our knowledge, this is the first time a genetic locus has been shown to influence motor progress

128 There was clear evidence for genetic locus heterogeneity upon examination of ten addi

129 Significant evidence for genetic locus heterogeneity was observed, with similar e

130 atients into subgroups relative to suspected genetic locus heterogeneity.

131 on of these disorders, some of which display genetic (locus) heterogeneity.

132 port the discovery of an approximately 16-kb genetic locus, HiGI1, that is present primarily in type

133 s study, we report the characterization of a genetic locus, HOS2, which is defined by three Arabidops

134 FCD2, at 18q21, is the second genetic locus identified for late-onset FCD.

135 norhabditis elegans gene rec-1 was the first genetic locus identified in metazoa to affect the distri

136 performed the first mutational analysis of a genetic locus immediately upstream of the streptolysin S

137 ndings suggest that modification of a second genetic locus in a defined neurodevelopmental regulatory

138 ilar in length to O3L were found at the same genetic locus in all vertebrate poxviruses.

139 We report the identification of a large genetic locus in B. bronchiseptica and B. parapertussis

140 These results identify a novel genetic locus in BALB/cJ mice that confers resistance to

141 These variants are encoded by the same genetic locus in diverse strains and have nearly identic

142 the transgene was integrated at a different genetic locus in each animal and was transmitted to appr

143 us Control Region by integrating at the same genetic locus in MEL cells, a LacZ gene driven by the hu

144 pondylitis, the MHC was the major permissive genetic locus in murine PG-induced spondylitis (PGIS).

145 b apart and may have appeared to be a single genetic locus in some sorghum populations.

146 eening revealed a broad distribution of this genetic locus in strains derived from various host speci

147 Using subcongenic mice, we found that a genetic locus in the 88-96 cM region was associated with

148 h, and confirm the importance of the LUCA-15 genetic locus in the control of apoptosis.

149 Here, Lee et al. identify a genetic locus in the nematode Caenorhabditis elegans tha

150 The discovery of a novel genetic locus in this family provides more evidence that

151 Identification of the responsible genetic locus in those mutants significantly extends our

152 compelling evidence for an involvement of a genetic locus includes linkage, we tested a candidate re

153 HK and RR trees with proteins from the same genetic locus indicated.

154 In conclusion, we identified a major genetic locus influencing BMI on chromosome 4p in Mexica

155 For each genetic locus, information about marker type or contig c

156 A single genetic locus is assumed to control fertility, and this

157 y affected, large families in which a single genetic locus is probably responsible for conferring sus

158 We describe here the first genetic locus isolated using these criteria: crooked leg

159 secretion pathway are clustered at the same genetic locus, known as RD1.

160 We have identified and characterized a genetic locus lic that is required for phosphorylcholine

161 Its restricted cellular distribution and genetic locus make it a candidate gene for the inherited

162 mmediately identifying the YACs containing a genetic locus mapped on Arabidopsis chromosome 2.

163 These findings suggest that this genetic locus may have an important impact on male ferti

164 The UCP2/UCP3 genetic locus may play a role in childhood body weight.

165 g autozygosity mapping, we have identified a genetic locus (MCPH1) for primary microcephaly, at chrom

166 Our previous study identified a new genetic locus, mrp, which is required for both fruiting

167 ral assays and linkage mapping to identify a genetic locus (nict-1) that mediates the phoretic intera

168 A genetic locus (no greater than 4.96 Mb in size) at Xp11.

169 have previously functionally defined a novel genetic locus nonpapillary renal carcinoma-1 (NRC-1) wit

170 ge studies demonstrate that nm1054 maps to a genetic locus not previously implicated in microcytic an

171 thway to tumorigenesis in the kidney via the genetic locus NRC-1.

172 c approach, we previously identified a novel genetic locus, NRC-1 (Nonpapillary Renal Cell Carcinoma

173 fiber genes are recombined into the natural genetic locus of adenovirus through unidirectional Cre-l

174 m of obese and diabetic individuals, and the genetic locus of adiponectin is linked to the metabolic

175 The wlb genetic locus of B. pertussis has been previously descri

176 The entire diffocin genetic locus of more than 20 kb was cloned and expresse

177 A genetic locus of Pseudomonas aeruginosa was identified t

178 C transporter complex, which is encoded by a genetic locus of the EAEC virulence plasmid pAA2.

179 Based on treatment history and genetic locus of the sequence changes, 39 of the sequenc

180 We have identified the genetic locus of these "diffocins" (open reading frames

181 enuated in a semidominant fashion by a major genetic locus on chromosome (Chr) 13.

182 In so doing, we have identified a genetic locus on chromosome 1 shared by all affected ind

183 16 introgression lines identified a dominant genetic locus on chromosome 5 from the wild relative tha

184 These data define and map a genetic locus on human chromosome 2 that extinguishes al

185 Previously we mapped a new genetic locus on mouse chromosome 1, designated sst1 (fo

186 Our results demonstrate that a genetic locus on rat chromosome 3, HR-SP1, contributes d

187 Chromosome 19q likely contains a genetic locus (or loci) that influences COPD through an

188 Our findings represent the first genetic locus outside of LOXL1 surpassing genome-wide si

189 of losses and gains of the tumor suppressor genetic locus p16(INK4A).

190 This report identifies a genetic locus physically and functionally linked to type

191 timing of transcriptional activation and the genetic locus play important roles in determining the fu

192 Searches can be conducted for genetic locus, probe or sequence accession number; searc

193 A single genetic locus produces two transcripts, TgFPPS and TgFPP

194 signed to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the

195 h root hair length and was associated with a genetic locus (QTL) on chromosome 2H.

196 mutants is mediated in part by agr RNAIII, a genetic locus regulated by mgrA.

197 cate that the previously identified specific genetic locus regulating strain-dependent collateral ves

198 Furthermore, our studies identify the first genetic locus regulating the orientation of cell divisio

199 The genetic locus required for cable pilus biogenesis is com

200 transposon mutagenesis we have identified a genetic locus required for the biosynthesis of LPS in B.

201 d which shows the presence or absence of the genetic locus required for Vi expression.

202 We also narrowed the genetic locus responsible for citrus polyembryony, a for

203 ication of the gene for BHD may reveal a new genetic locus responsible for renal neoplasia and for lu

204 The genetic locus responsible for this natural variant, VICT

205 The genetic locus responsible for this phenotype in FA19 was

206 We have defined the genetic locus responsible for ultraviolet B susceptibili

207 The SAP gene has been identified as the genetic locus responsible for X-linked lymphoproliferati

208 phism segregate as if controlled by a single genetic locus, resulting from tight genetic linkage betw

209 We report a NK complex-linked genetic locus, Rhs1, whose alleles influence the magnitu

210 d, each gene group is tested for a causative genetic locus shared with the clinical trait of interest

211 Here, we describe a new genetic locus, SIAMESE (SIM), required for coordinating

212 We have previously identified an NZM2410 genetic locus, Sle2, which is associated with the produc

213 In the majority of AT/RT, LOH occurs at the genetic locus SNF5 (Ini1/BAF47/Smarcb1), which functions

214 Three forms of a single genetic locus specify this species' three mating types:

215 bacterium tuberculosis, we have identified a genetic locus sst1 on mouse chromosome 1, which controls

216 terium tuberculosis (Mtb), we identified the genetic locus sst1 that controls the progression of pulm

217 rd gene segments are organized into a single genetic locus (Tcra/Tcrd locus) that undergoes V(D)J rec

218 ruginosa strain ZK2870 and identify a second genetic locus, termed psl, involved in the production of

219 ino acid 180 of the GCD1 gene product as the genetic locus that allows translational regulation upon

220 These results show that a narrow genetic locus that contains Csnk1e is associated with di

221 units (AccD1 to -6), with accD6 located in a genetic locus that contains members of the FAS II comple

222 Rhg4 is a major genetic locus that contributes to soybean cyst nematode

223 Suppose there is one genetic locus that controls the capacity to internalize

224 is located at or near the mouse Sac locus, a genetic locus that controls the detection of certain swe

225 phoA insertion maps to a recently identified genetic locus that encodes products that are predicted t

226 Rcr3 and Pip1 reside on a genetic locus that evolved over 36 million years ago.

227 Our data show that the same genetic locus that has been identified as a marker for t

228 This is the first genetic locus that has been shown to influence the risk

229 The finding of a genetic locus that has extensive effects on neuronal dev

230 Taken together, our results identify a genetic locus that influences enamel structure and estab

231 suggests the existence of a third, unlinked genetic locus that influences the interaction between Cr

232 l of islet cell carcinogenesis to identify a genetic locus that influences tumor progression to an in

233 HLA, this is the strongest evidence yet of a genetic locus that is both linked to and associated with

234 which in mouse is tightly linked to the SOA genetic locus that is involved in detecting the bitter c

235 lity that MCD type II may be due to the same genetic locus that is involved in MCD type I.

236 th ALS and FTD or either ALS or FTD alone, a genetic locus that is linked to ALS with FTD located bet

237 cterization of a transgenic mouse revealed a genetic locus that is specifically regulated in T cells.

238 gastric Le phenotype, and reveal a bacterial genetic locus that is subject to host-driven selection p

239 e expressed from what appears to be a single genetic locus that largely coincides with an approximate

240 he B. hermsii gene encoding FhbA is a single genetic locus that maps to a linear plasmid of approxima

241 In addition, we have mapped a genetic locus that may be responsible for the LTNP trait

242 m; P=0.03), suggesting some effect from a BS genetic locus that modifies hypertrophy induced by the c

243 ice and suggest that mouse Chr. 4 contains a genetic locus that modulates the mechanosensitivity of b

244 The centromere is the genetic locus that organizes the proteinaceous kinetocho

245 these strains were two with disruptions in a genetic locus that putatively codes for a transcriptiona

246 LepB is positioned within a genetic locus that resembles the locus containing the ex

247 viously based on evidence from only a single genetic locus that this species may be either the closes

248 died patients is due to a defect in the same genetic locus that underlies the cancer-prone genetic di

249 We report here the identification of a genetic locus that, when mutated, results in a precociou

250 We named this genetic locus the commensal colonization factors (ccf).

251 ly reported association of RA with the PTPRC genetic locus, the present study was undertaken to test

252 We have named the mutant alleles and the genetic locus they define brachyenteron (byn); phenotypi

253 FCD1 is the first genetic locus to be identified for late-onset FCD, a com

254 th congenital TTP and mapped the responsible genetic locus to chromosome 9q34.

255 However, the only bona fide genetic locus to emerge from extensive analysis of CMM s

256 o insert genes at a previously characterized genetic locus to make plant transformation and transgene

257 present here an inducible system to target a genetic locus to the nuclear lamina in living mammalian

258 n mice, highlighting the STPP as a potential genetic locus underlying interindividual differences in

259 The genetic locus underlying this phenotype was mapped to ni

260 In this report, we characterize a genetic locus unique to staphylococci called rsr that ha

261 The only genetic locus universally accepted to be important as a

262 or the less restrictive phenotype of CAD, no genetic locus was detected, suggesting that CAD and MI m

263 s jannaschii was purified and sequenced: its genetic locus was found to correspond to gene MJ0626.

264 In the same genetic locus, we also identified a two-component system

265 ented the most significant variation in this genetic locus were assessed.

266 ozygous for B6 markers of this chromosome 11 genetic locus were, respectively, highly susceptible or

267 tern, suggesting the involvement of a single genetic locus, which has been named TOX2.

268 Genetic association studies indicate that a genetic locus, which includes the CHRNA5-CHRNA3-CHRNB4 g

269 This genetic locus, which we have named mustard (mtd), contai

270 Children with risk alleles at the 17q21 genetic locus who wheeze during rhinovirus illnesses hav

271 Thus, the two bin2 mutations define a novel genetic locus whose gene product might play a role in BR

272 ultrasound/DXA measures and points to a new genetic locus with potential implications for better und

273 Treponema denticola harbours a genetic locus with significant homology to most of the p

274 rc, these alleles show that crc is a complex genetic locus with two overlapping lethal complementatio

275 report the functional definition of a novel genetic locus within human chromosome 10pter-q11 that me

276 A specific genetic locus within pgm, which shares similarity to a p

277 We previously described a novel genetic locus within the ULb' region of the human cytome

278 We describe a novel genetic locus, wunen (wun), required for guidance of ger

279 Here we report a new genetic locus, XLIS, mapped by linkage analysis of five

280 ationale for the designation of the previous genetic locus ybdA as entS to reflect its relevant biolo