ライフサイエンスコーパス: genetic map

1 rmative datasets (e.g. physical, optical and genetic maps).

2 rganized around a physical map anchored to a genetic map.

3 enced 192 segregants to generate an accurate genetic map.

4 which were in good agreement with the NCCCWA genetic map.

5 ch representing on average <3% of the barley genetic map.

6 4, on the reference 'TM-1' x 'Pima 3-79' RIL genetic map.

7 for expected linkage disequilibrium using a genetic map.

8 d BAC-to-BAC sequences and a high-resolution genetic map.

9 ated the genomic contigs with a high-density genetic map.

10 l for comparing BAC-based physical maps with genetic maps.

11 uickly improve marker order and placement on genetic maps.

12 ination with optical, chromosome-contact and genetic maps.

13 and as a resource to produce high-resolution genetic maps.

14 de CRM was constructed from 28 public cotton genetic maps.

15 localizing these effects on high-resolution genetic maps.

16 of the relationship between the physical and genetic maps.

17 gle-molecule reads integrated to genomic and genetic maps.

18 AC)-end sequences and genotype-by-sequencing genetic maps.

19 vels in S. latifolia PAR genes identified by genetic mapping.

20 contain a translocation when analyzed using genetic mapping.

21 slocations: pollen viability and genome-wide genetic mapping.

22 orse collections for phenotypic screening or genetic mapping.

23 el system to conduct high-density functional genetic mapping.

24 etic screens usually involves time-consuming genetic mapping.

25 ocessing and quantitative analysis and their genetic mapping.

26 er by as much as 180 degrees on the circular genetic map, a distance of >/=2 million base pairs.

27 Further, conditional genetic mapping analysis for GYD given its three compone

28 Here we report a combined sequence and genetic mapping analysis in outbred rats that maps 355 q

29 Strategically selected markers from the genetic map and draft genome assembly were employed to s

30 le-genome simple sequence repeat (SSR)-based genetic map and on mapping sex determination as two qual

31 The genetic map and SSLP marker database constitute an essen

32 The assembly was anchored to a 992-locus genetic map and was annotated by comparison with >1.3 mi

33 A combination of genetic mapping and candidate gene analysis presents Cdk

34 in the pen1-1 genetic background as well as genetic mapping and characterization of the Arabidopsis

35 The genetic mapping and chromosome substitution line-based d

36 By genetic mapping and complementation experiments, we foun

37 intervals predicted to be centromeric DNA by genetic mapping and DNA sequence analyses.

38 Genetic mapping and gene expression analyses localized t

39 Despite years of research involving genetic mapping and gene expression profile analysis of

40 Recent genetic mapping and gene-phenotype studies have revealed

41 transmitted dominantly to her offspring, and genetic mapping and genome sequencing revealed a new mut

42 the development of powerful populations for genetic mapping and genome-wide association studies (GWA

43 types of important genetic markers useful in genetic mapping and genotyping.

44 By genetic mapping and in vitro analysis of enzyme activity

45 In particular, the problem of genetic mapping and linkage-one of the first efforts tow

46 Together, our results from genetic mapping and molecular analysis provide an exampl

47 A combination of sequence analysis, genetic mapping and molecular cytogenetic methods with c

48 We used genetic mapping and near isogenic lines (NILs) to identi

49 We review studies using genetic mapping and phylogenetic inferences, which can h

50 Genetic mapping and physical mapping identified the inve

51 se gene silencing, gene expression analysis, genetic mapping and population genomics to study the gen

52 Through genetic mapping and positional cloning, we identified th

53 in the suppressor mutants were identified by genetic mapping and re-sequencing of the mutant genomes.

54 A combination of genetic mapping and retroillumination photography was us

55 Genetic mapping and sequencing of mutant alleles confirm

56 mal recessive syndrome of neonatal diabetes, genetic mapping and subsequent sequencing identified mut

57 ure of human diseases governs the success of genetic mapping and the future of personalized medicine.

58 ased experimental data, involving systematic genetic mapping and whole-genome sequencing, to generate

59 New markers, genetic maps and extensively curated qualitative/Mendeli

60 h large-scale cDNA analyses, construction of genetic maps and gene mapping studies aiming to link phe

61 lity of SLAF markers for rapid generation of genetic maps and QTL analysis has been demonstrated for

62 The comparison between genetic maps and the reference genome highlighted 85% of

63 finium SNP array, constructed a 7,185-marker genetic map, and anchored on the map contigs totaling 4.

64 tudy we combined next-generation sequencing, genetic mapping, and a set of physiological traits of th

65 avioral and anatomical analyses, physiology, genetic mapping, and gene knockdowns.

66 r the array, 4.5% were markers from existing genetic maps, and 61% were selected based on distributio

67 rtificial chromosome libraries, physical and genetic maps, and molecular markers, combined with genet

68 More generally, our genetic mapping approach should be powerful for high-res

69 We apply a powerful genetic mapping approach to the Wellcome Trust Case-Cont

70 D. melanogaster X chromosome using a classic genetic mapping approach.

71 However, as in conventional genetic mapping approaches, mapping-by-sequencing requir

72 Using a combination of genetic mapping approaches, we show that the white reces

73 Genetic maps are key tools in genetic research as they c

74 ifers have recently been produced, but dense genetic maps are needed to comprehend genome macrostruct

75 grate sequence information with physical and genetic maps are scarce.

76 Accurate genetic maps are the cornerstones of genetic discovery,

77 d displayed a nonuniform distribution on the genetic map around the donor r1-sc:m3 locus.

78 Genetic mapping associated a large deletion on chromosom

79 on of a single-nucleotide polymorphism-based genetic map at the F4 stage of the mapping population.

80 00 meioses and have constructed sex-specific genetic maps at a previously unachievable resolution.

81 Compared to the human genetic map, broad-scale recombination rates tend to be

82 ap between markers D3Mit147 and D3Mit19 on a genetic map, but the physical map places RPE65 outside t

83 ed reliably and used to generate a SNP-based genetic map by genotyping recombinant inbred lines from

84 Genetic mapping by bulk segregation analysis excluded al

85 Here we present a statistical framework for genetic mapping by utilizing collective information in b

86 Here, we argue that genetic mapping can play a more important role in studyi

87 Most of the published cotton genetic maps can be viewed and compared using CMap, a co

88 g the gap between large-scale and fine-scale genetic mapping, can reveal new features of the recombin

89 R) framework map, we produced a high-density genetic map comprising over 600 SFPs, GEMs and SSRs.

90 Conventional genetic mapping confirmed that the causal mutations were

91 SSLPs were genotyped, yielding a 2886-marker genetic map consisting of 10 major linkage groups betwee

92 Consensus genetic maps constructed from multiple populations are a

93 approach was used to develop SNP markers for genetic map construction, and quantitative trait loci (Q

94 ental RIL populations to produce a consensus genetic map containing 37 372 SNPs.

95 ibrium methodology to generate an integrated genetic map containing 4,817 SNPs, which spanned a total

96 bled the construction of two high-resolution genetic maps containing 1832 and 1773 markers with an av

97 The final genetic map contains 7,192 successfully mapped markers t

98 Here, we use genetic mapping, copy-number analysis, exclusion of muta

99 We have revisited high-resolution genetic map data from a large heterogeneous mouse popula

100 ese results prompted an analysis of existing genetic mapping data, which showed that meiotic reciproc

101 ParentChecker efficiently improves genetic mapping datasets for cases where parental inform

102 The genetic map derived from this population provided no ind

103 rphisms (SNPs) have become popular tools for genetic mapping, discovery and application of SNPs in po

104 , which provides almost a 4-fold increase in genetic map distance compared with conventional mapping

105 easure and susceptible to confounding during genetic mapping due to correlation with flowering and su

106 The strategies presented are applicable to genetic mapping efforts in all plant species with simila

107 This genetic map enabled the anchoring of 100 Mb of WGS and 4

108 This first genetic map enables us to study the goldfish genome evol

109 portance, several computational solutions to genetic map estimation exist, mostly implemented as stan

110 holds great promise to extend the utility of genetic mapping, even when QTL effects are modest or com

111 onal phenomenon that we observed through our genetic mapping experiments was that the T-DNA junctions

112 To underpin construction of a genetic map facilitating isolation of these S locus gene

113 We performed genetic mapping, followed by next-generation sequencing

114 In this study, a high-density genetic map for cultivated cucumber was developed that c

115 We constructed a genetic map for the Z chromosome of the Gouldian finch (

116 We present a genetic map for Xenopus tropicalis, consisting of 2886 S

117 oach to construct an integrated physical and genetic maps for apple.

118 are fewer tools available which can display genetic maps for less well-characterized species, and in

119 order 10 Mb) features of previously reported genetic maps for mouse.

120 estimate and test these parameters within a genetic mapping framework using a new powerful computati

121 orporating integrated square errors into the genetic mapping framework.

122 eloped methodology to construct a fine-scale genetic map from high-throughput sequence data from 10 W

123 ide polymorphisms (SNPs) were identified for genetic mapping from rp2 P450s and other genes revealing

124 e that encodes PRDM9, we inferred fine-scale genetic maps from population resequencing data for two b

125 d sequence tags (ESTs), markers, trait loci, genetic maps, genes, taxonomy, germplasm, publications a

126 genomewide data sets, such as errors in the genetic map, haplotype phase uncertainty, and SNP ascert

127 massively parallel sequencing technologies, genetic mapping has become the rate limiting step in mam

128 ailability of whole-genome sequencing (WGS), genetic mapping has become the rate-limiting step, inhib

129 Genetic mapping has been used as a tool to study the gen

130 Although genetic maps have been developed for numerous plant spec

131 s of interest: haplotype-based computational genetic mapping (HBCGM).

132 This conclusion is supported by genetic mapping, identification of a missense mutation i

133 Genetic mapping identified a genomic locus containing th

134 Genetic mapping identified the candidate gene linking AH

135 Genetic mapping identifies strain line 19 fusion (F) pro

136 ome Database include comprehensive update of genetic maps, implementation of new classification terms

137 Genetic mapping implicated Akt3, one of four candidates

138 demonstrate that utilization of the revised genetic map improves QTL mapping, partially due to the r

139 reconstruction of sub-pedigrees suitable for genetic mapping in a systematic way.

140 Using genetic mapping in cichlid fishes, we identified shared

141 , we performed sequenced-based, high-density genetic mapping in F2 hybrids between synthetic and natu

142 We use genetic mapping in large F(2) intercrosses between Gough

143 resent MULTIPOOL, a computational method for genetic mapping in model organism crosses that are analy

144 Genetic mapping in this population, derived from a cross

145 oach that localizes causal variants based on genetic maps in linkage disequilibrium units (LDU maps).

146 folds using Illumina mate-pair libraries and genetic map information.

147 ure, CloudMap allows users to sharply define genetic map intervals graphically and to retrieve very s

148 e clustering and network reconstruction with genetic mapping into a unifying framework.

149 ome and incorporated SSLP markers from other genetic maps into this new framework.

150 The updated genetic map is visualized using the comparative genetic

151 Resolution of genetic mapping is limited by the recombination rate.

152 Phenovariance may be obscured when genetic mapping is performed using highly divergent stra

153 Further genetic mapping is warranted at these loci.

154 ed by one parameter, the ratio between total genetic map length (G) and physical map length (P), meas

155 figl1 mutations, which increased the hybrid genetic map length from 389 to 3,037 cM.

156 ombining pseudo-autosomal region (PAR) whose genetic map length is approximately 25 cM in both male a

157 0), the parameter k predicts the increase of genetic map length over the increase of physical map len

158 he effect of variant density, conditional on genetic map length, on the power to resolve IBD segments

159 A combination of genetic mapping, linkage group selection, and functional

160 Refined genetic mapping localizes vitiligo risk in the HLA-A reg

161 By using a combination of genetic mapping, mate-choice experiments, field observat

162 European ancestry in the Americas to build a genetic map measuring the probability of crossing over a

163 icitly incorporate their LD information into genetic mapping models (tmLD).

164 cent genomic studies have provided a refined genetic map of acute lymphoblastic leukemia (ALL) and in

165 We have defined a high-resolution genetic map of direct interference by Cascade and Cas3,

166 Here we present a high-resolution genetic map of DS phenotypes based on an analysis of 30

167 Our project has patched the hole in the genetic map of Eurasia: we demonstrated complexity of ge

168 ime of development, which provides the first genetic map of neurogenesis in a cephalopod.

169 A consensus genetic map of tetraploid cotton was constructed using s

170 The resulting sex-averaged genetic map of the DO population is highly concordant wi

171 se population and have constructed a revised genetic map of the mouse genome, incorporating 10,195 si

172 We created a genetic map of the sex chromosome and its homeologs in F

173 A high-resolution genetic map of this region delineated the location of ui

174 screenings that can more readily decode the genetic map of various biological processes.

175 e reference genome sequence was validated by genetic mapping of 54,000 SNPs, and annotated with 26,66

176 Here we report genetic mapping of a membrane transporter (ABCC2) to a l

177 Using genetic mapping of a strong cutin-deficient mutation, we

178 Here we report discovery and genetic mapping of additional vibrator modifiers, Mvb2 a

179 Genetic mapping of affected individuals resulted in the

180 in these half-tetrad individuals allowed the genetic mapping of all 19 centromeres of the Brassica A

181 od 1950-1970, groundbreaking research on the genetic mapping of Chlamydomonas reinhardtii and the use

182 Genetic mapping of complex diseases to date depends on v

183 Together, these results make clear that genetic mapping of complex phenotypes is within reach, e

184 f genome-wide association studies (GWAS) for genetic mapping of complex traits, most existing GWAS me

185 Through genetic mapping of disease loci and whole-exome sequenci

186 In support of this, genetic mapping of DNA methylation reveals that most of

187 Genetic mapping of impulsive action in the BXD panel ide

188 ration of these various data sets enable the genetic mapping of many new phenotypes and facilitates t

189 e analysis was the primary tool used for the genetic mapping of Mendelian and complex traits with fam

190 Genetic mapping of mutations in model systems has facili

191 re, and suggest the potential of the VRC for genetic mapping of quantitative trait loci underlying su

192 Despite advances in genetic mapping of quantitative traits and in phylogenet

193 Genetic mapping of resistance mutation coupled with pote

194 characterized in Drosophila melanogaster by genetic mapping of resistance to the cyclodiene dieldrin

195 e physical maps were validated with FISH and genetic mapping of SNP markers derived from BES.

196 ses, this result is consistent with previous genetic mapping of teratoma susceptibility loci to the r

197 .M-H2(k/b) (MCMV resistant) mice for precise genetic mapping of the critical interval.

198 al data, we used codominant genic markers in genetic mapping of the dioecious plant Silene latifolia,

199 Recent genetic mapping of the molecular evolution of pancreatic

200 The target link to GyrB was confirmed by genetic mapping of the mutations conferring resistance t

201 In the current study we carried out further genetic mapping of this latency phenotype and investigat

202 High resolution genetic mapping of transcript levels in HMDP, reveals bo

203 tic basis for differential responses through genetic mapping of V2O5-induced lung collagen content in

204 Similar genetic mapping of Wilms' tumor-1-positive mesothelial c

205 Here, we report genetic mapping of XLCOD to Xq26.1-qter.

206 ocedure for integration of both physical and genetic maps of a genome.

207 The implications of this strategy for the genetic maps of human, mouse, rat, chicken, honeybee, wo

208 These models provide comprehensive genetic maps of lineage-specific Notch receptor expressi

209 In this article, we present genetic maps of recently active Insertion Sequence (IS)

210 These genetic maps of recently active IS elements and the seve

211 bined multiple data sets to build integrated genetic maps of the M. guttatus species complex (section

212 We constructed high-density genetic maps of Zoysia japonica using a restriction site

213 interactions between segments distant on the genetic map on contact frequencies determined experiment

214 Genetic mapping on fully sequenced individuals is transf

215 A genetic map ordering 1124 microsatellite loci spanning a

216 hat the F3'5'H gene cosegregates with b in a genetic mapping population, strongly support our hypothe

217 Genetic mapping populations have facilitated identificat

218 ish causal relationships among phenotypes in genetic mapping populations.

219 Molecular genetic mapping positioned the turnout mutation within a

220 and corresponded well to previously reported genetic map positions.

221 We developed a next-generation computational genetic mapping program with advanced features to identi

222 Genetic maps provide a means to estimate the probability

223 Comparative genetic mapping provides insights into the evolution of

224 = 22), the use of transcript-derived SNPs in genetic maps provides opportunities for automated genoty

225 nted the most promising candidate traits for genetic mapping related to BP based on strong heritabili

226 Statistical methods for genetic mapping rely on a key assumption, that is, trait

227 pressures, high diversity and precision for genetic mapping remain.

228 mately 70 and 90% of the total F. virginiana genetic map resides within 10 and 20 cM of a marker on t

229 Genetic mapping restricted to genome-wide enhancer singl

230 urthermore, our gene-expression analysis and genetic mapping results suggest that cis-regulatory chan

231 at nevertheless had a translocation based on genetic mapping results.

232 Genetic mapping revealed that a locus on chromosome 6 li

233 Genetic mapping revealed that the pe locus represents a

234 Genetic mapping revealed that the reduction in acylsugar

235 By genetic mapping, sequence analysis of candidate genes an

236 We conducted a systematic study including genetic mapping, sequencing, and functional analyses to

237 Genetic mapping showed that phosphorylated LRP6 degradat

238 Through fine-scale genetic mapping, site-directed mutagenesis, and transgen

239 ts that are challenging to handle by current genetic mapping software with graphical interface.

240 Studio facilitates the visual comparison of genetic map solutions from third party software, aiding

241 hese, 928 were incorporated into a consensus genetic map spanning 680 cM with 11 linkage groups and a

242 In this study, we use a genetic mapping strategy that involves recurrent backcro

243 Evidence from human myopia genetic mapping studies (MYP3 locus), modulated animal m

244 RECENT FINDINGS: Computational genetic mapping studies have identified the genetic basi

245 Genetic mapping studies have suggested that diploid cott

246 eous and large enough to permit well-powered genetic mapping studies of quantitative traits relevant

247 Genetic mapping studies of quantitative traits typically

248 se mechanisms of NS are not well understood, genetic mapping studies suggest a multitude of unknown s

249 Genetic mapping studies suggest high genetic heterogenei

250 at reproductive traits should be amenable to genetic mapping studies, and the results we present here

251 digrees offer many well-known advantages for genetic mapping studies, including cost-efficient study

252 Furthermore, in genetic mapping studies, Mx1 was identified as the major

253 the evidence for pleiotropy in contemporary genetic mapping studies, new and established analytical

254 teractions (HGIs) are difficult to detect in genetic mapping studies, therefore, few examples of them

255 In genetic mapping studies, we identify four additive modif

256 depth to achieve desired marker density for genetic mapping studies.

257 diseases in humans, causal loci uncovered by genetic-mapping studies explain only a minority of the h

258 We performed a genetic mapping study using the Immunochip to determine

259 ial benefits of using population isolates in genetic mapping, such as reduced genetic, phenotypic and

260 Genetic mapping suggested important roles for variation

261 t any kind of available information, such as genetic map symbols, soybean gene names or phenotypic tr

262 tations in the fly genome by combining rough genetic mapping, targeted DNA capture, and second genera

263 rabidopsis thaliana populations suitable for genetic mapping that have constitutively reduced HSP90 l

264 We used genetic maps that capture detailed linkage disequilibriu

265 In combination with the high-resolution genetic map, the draft genome paves the way for better m

266 Together with comparative genetic mapping, this has revealed that sex-determining

267 Comparison of this cowpea genetic map to reference legumes, soybean (Glycine max)

268 ckcross design, we performed high-resolution genetic mapping to determine the genetic architecture of

269 Here we apply bioinformatic and genetic mapping to identify the sex-determining (sex) re

270 , but previous applications involved tedious genetic mapping to pinpoint the causative mutations.

271 integrated it with physical and high-density genetic maps to create a chromosome-scale draft sequence

272 RDN1 gene, Medtr5g089520, was identified by genetic mapping, transcript profiling, and phenotypic re

273 a five- to eight-fold higher resolution than genetic maps used in similar studies.

274 The constructed genetic map using the SFP markers predicted from our pro

275 report a fast and cost-effective method for genetic mapping using next-generation sequencing that co

276 Genetic mapping using SNP markers confirms its position

277 We describe analytical methods for genetic mapping using this resource and demonstrate the

278 comparing whole genome polymorphism data and genetic maps using a coalescent modeling framework, we e

279 ility of the integration of the physical and genetic maps using this SNP-based strategy is described,

280 Genetic mapping utilized patient samples from Germany (2

281 Quantitative genetic mapping utilizing crosses between D. tenebrosa a

282 etic map is visualized using the comparative genetic map viewer CMAP.

283 A local genetic map was constructed by genotyping three flanking

284 Genetic mapping was recently used to identify the underl

285 ning transcriptome, iTRAQ-based proteome and genetic mapping was taken to compare the ovules of the X

286 By anchoring the S. pennellii genome to the genetic map, we define candidate genes for stress tolera

287 cent developments in parallel computing, and genetic mapping, we derive, de novo, a sequence assembly

288 By genetic mapping, we identified a frame shift mutation in

289 whole genome SNP database and computational genetic mapping were used to analyze the murine genetic

290 Genetic maps were constructed following identical rules

291 terspecific Gossypium hirsutumxG. barbadense genetic maps were used for assembling a high density con

292 Historically, 'genetic maps' were used primarily to locate genes.

293 omes resulted in the de novo construction of genetic maps which were in good agreement with the NCCCW

294 A high level of synteny was found with pine genetic maps, which should facilitate the transfer of st

295 e divide the genome into windows of constant genetic map width and then tabulate the number of distin

296 ility of a high-quality sequence anchored to genetic maps will accelerate the identification of genes

297 The genetic maps will assist in genome sequence assembly, ta

298 tic variation enabled us to build a detailed genetic map with nine linkage groups.

299 e diploid D genome and the tetraploid cotton genetic map, with only a few minor possible structural r

300 somes via the development of a comprehensive genetic map, without a physical map intermediate.