ライフサイエンスコーパス: genetic recombination

1 g the 'Role for the c-Abl tyrosine kinase in genetic recombination'.

2 etic variation or by subsequent mutation and genetic recombination.

3 strand exchange, the two essential steps of genetic recombination.

4 ble-strand breaks (DSBs) and is required for genetic recombination.

5 Holliday junctions are intermediates in genetic recombination.

6 t Y chromosomes degenerate because they lack genetic recombination.

7 ear to be due to complementation rather than genetic recombination.

8 in displacing RPA in the initiation stage of genetic recombination.

9 revealing new details about the mechanics of genetic recombination.

10 s architecture has potential implications in genetic recombination.

11 nt model system for understanding homologous genetic recombination.

12 g in DNA transposition-a specialized form of genetic recombination.

13 e Holliday junction is a key intermediate in genetic recombination.

14 Thus, long CTG.CAG tracts are hot spots for genetic recombination.

15 r gene that is activated by Cre/lox-mediated genetic recombination.

16 aged DNA or stalled replication can initiate genetic recombination.

17 virus replication and, in some cases, viral genetic recombination.

18 family of recombinases active in homologous genetic recombination.

19 damage, and serve to ensure the fidelity of genetic recombination.

20 e four-way DNA junction that is important in genetic recombination.

21 is a key DNA intermediate in the process of genetic recombination.

22 lliday junction is a central intermediate in genetic recombination.

23 ecBCD enzyme, it is completely defective for genetic recombination.

24 ility, particularly to prevent 'promiscuous' genetic recombination.

25 o play different roles during DNA repair and genetic recombination.

26 ne family of strand transferases involved in genetic recombination.

27 DMC1 family of strand transferases acting in genetic recombination.

28 he removal of nonhomologous DNA tails during genetic recombination.

29 ost intensively studied enzyme in homologous genetic recombination.

30 sviruses by regulating viral replication and genetic recombination.

31 ast one PspA has been acquired via localized genetic recombination.

32 le functions in DNA replication, repair, and genetic recombination.

33 lliday junction is a central intermediate in genetic recombination.

34 to remove 3' nonhomologous DNA tails during genetic recombination.

35 lain the alignment of homologous DNAs during genetic recombination.

36 DNA synthesis and is involved in retroviral genetic recombination.

37 of a DNA Holliday junction is a key step in genetic recombination.

38 acteriophage lambda suit it for the study of genetic recombination.

39 th MSH2 and functions in mismatch repair and genetic recombination.

40 is a central intermediate in the process of genetic recombination.

41 ctions in DNA double-strand break repair and genetic recombination.

42 branch migration is a fundamental process in genetic recombination.

43 ion that can occur for variants generated by genetic recombination.

44 change reactions suggestive of a key role in genetic recombination.

45 n resolves DNA intermediates produced during genetic recombination.

46 e Holliday junction is a key intermediate in genetic recombination.

47 segregation at MII may also be influenced by genetic recombination.

48 ration of Holliday junction intermediates in genetic recombination.

49 p between the processes of SOS induction and genetic recombination.

50 erevisiae RAD52 gene plays a pivotal role in genetic recombination.

51 n of cell cycle checkpoints, DNA repair, and genetic recombination.

52 in DNA repair and other processes involving genetic recombination.

53 s integrated in tumor DNA carried markers of genetic recombination.

54 e males, or otherwise exhibit some degree of genetic recombination.

55 the genome but account for nearly all of the genetic recombination.

56 rand exchange reaction as part of homologous genetic recombination.

57 e of a pathogenicity island acquired through genetic recombination.

58 ism of antigenic variation is not homologous genetic recombination.

59 ich we particularly discuss the variation of genetic recombination.

60 embedded within a 3,113-kb region that lacks genetic recombination.

61 ed that ST-452 could have originated through genetic recombination.

62 l DNA and is also involved in DNA repair and genetic recombination.

63 y movements that ultimately serve to promote genetic recombination.

64 To study genetic recombination, 16 progeny clones were genotyped

65 Regulation of genetic recombination, a proposed role for RecQ helicase

66 shift in IYSVBR genotype is attributable to genetic recombination, abundance of purifying selection,

67 DNA strand exchange plays a central role in genetic recombination across all kingdoms of life, but t

68 izobium species we observed coexist with low genetic recombination across their core genomes.

69 somal rearrangements, which we attributed to genetic recombination, activity of mobile elements, and

70 Genetic recombination affects levels of variability and

71 iple functions, suggesting that variation of genetic recombination along a chromosomal arm is the res

72 ysis of individual segment datasets suggests genetic recombination also occurs.

73 e bacterium and that these pathogens utilize genetic recombination and a large, noncore set of genes

74 same kind of combinatorial diversity as does genetic recombination and antibody formation.

75 The major pathway of genetic recombination and DNA break repair in Escherichi

76 RAD51, RAD55, and RAD57 genes, required for genetic recombination and DNA double-strand-break repair

77 day intermediates and correct the defects in genetic recombination and DNA repair associated with ina

78 cells, RAD52 protein plays a central role in genetic recombination and DNA repair by (i) promoting th

79 of RecB and tested the resulting mutants for genetic recombination and DNA repair in vivo.

80 tion of Holliday junctions that arise during genetic recombination and DNA repair.

81 i process recombination intermediates during genetic recombination and DNA repair.

82 ichia coli process Holliday junctions during genetic recombination and DNA repair.

83 ranch migration of Holliday intermediates in genetic recombination and DNA repair.

84 ranch migration of Holliday junctions during genetic recombination and DNA repair.

85 ic data has implicated BLM in the process of genetic recombination and DNA repair.

86 NA strand-exchange reaction utilized in both genetic recombination and DNA repair.

87 Genetic recombination and double-strand break repair adv

88 double-stranded DNA and is involved in both genetic recombination and double-strand break repair in

89 The RAD54 and RAD51 genes are involved in genetic recombination and double-strand break repair in

90 pendent recombinases plays a crucial role in genetic recombination and double-stranded DNA break repa

91 Chromosome inversions suppress genetic recombination and establish co-adapted gene comp

92 Amazingly, host factors affecting viral genetic recombination and evolution have also been ident

93 AD51 gene function is required for efficient genetic recombination and for DNA double-strand break re

94 nd breaks that occur during DNA replication, genetic recombination and gene rearrangements.

95 lity to integrate into tissues could explain genetic recombination and generation of novel pathogens.

96 Escherichia coli is required for homologous genetic recombination and induction of the SOS regulon.

97 ter centroblasts, which undergo simultaneous genetic recombination and massive clonal expansion.

98 und to be deficient in repair of DNA damage, genetic recombination and meiosis.

99 n of spermatogonia, spermatocytes undergoing genetic recombination and meiotic divisions, and differe

100 mosome arms, regions characterized by higher genetic recombination and more repeat sequences than aut

101 ifically, DNA shuffling and other methods of genetic recombination and mutation have resulted in the

102 ral intermediate state of DNA for homologous genetic recombination and other genetic processes such a

103 During general genetic recombination and recombinational DNA repair, DN

104 omyces cerevisiae RAD51 gene is required for genetic recombination and recombinational repair of DNA

105 cerevisiae RAD51 gene product takes part in genetic recombination and repair of DNA double strand br

106 es cerevisiae Rad51 protein is important for genetic recombination and repair of DNA double-strand br

107 gy in duplex DNA is central to understanding genetic recombination and repair of double-strand breaks

108 is formed as a transient intermediate during genetic recombination and repair processes in the cell.

109 ired in mammalian cells for normal levels of genetic recombination and resistance to DNA-damaging age

110 H1 and HMG-1 in biological processes such as genetic recombination and retroviral integration.

111 ntial to the two distinct cellular events of genetic recombination and SOS induction in Escherichia c

112 During genetic recombination and the recombinational repair of

113 rtant roles in the late stages of homologous genetic recombination and the recombinational repair of

114 mplex protein machines, initiates homologous genetic recombination and the repair of broken DNA.

115 rs of the RAD52 epistasis group required for genetic recombination and the repair of DNA double-stran

116 s RAD51 or RAD52 result in severe defects in genetic recombination and the repair of double-strand DN

117 Genetic recombination and, in particular, genetic shuffl

118 B cells that have class switched to IgD via genetic recombination (and thus become class switched to

119 to chromosomal instability, abnormalities in genetic recombination, and defective signaling to progra

120 s of Msh2, Msh3, Rad1, and Rad10 proteins in genetic recombination are discussed.

121 sults indicate that mismatches formed during genetic recombination are processed differently than dur

122 The presumed advantages of genetic recombinations are difficult to demonstrate dire

123 Y (or W) chromosomes lack genetic recombination, are male- (female-) limited, and

124 Using a promoter trap that relies on genetic recombination as a reporter of gene expression,

125 Genetic recombination associated with sexual reproductio

126 tes that have deleted fetA sequences through genetic recombination at repetitive elements.

127 on the silencing of Pol II transcription and genetic recombination at the ribosomal DNA locus (rDNA)

128 es that confer an advantage to sexuality and genetic recombination, at either the population or indiv

129 tion should consider the possibility of rare genetic recombination, because such events seem to be ne

130 Interstrain genetic recombination between distant loci in the VP1 an

131 like its bacterial homologue RecA, catalyzes genetic recombination between homologous single and doub

132 lts provide direct experimental evidence for genetic recombination between two different retroviral s

133 that induced viral co-infection facilitated genetic recombination between two different viruses, the

134 stacles such as high sequence similarity and genetic recombinations between CYP2D6 and evolutionarily

135 he co-existence of precursor cells harboring genetic recombinations between the immunoglobulin heavy-

136 tified mutations in MSH2 that do not disrupt genetic recombination but confer a strong defect in mism

137 negatively correlate with the rates of local genetic recombination, but no significant correlation be

138 n of bacteriophage lambda acts in homologous genetic recombination by catalyzing the annealing of com

139 sion repair proteins have been implicated in genetic recombination by experiments in Saccharomyces ce

140 the only hyperthermophilic archaeon in which genetic recombination can be assayed by conjugation and

141 Genetic recombination can be important evolutionarily in

142 Genetic recombination can lead to the formation of inter

143 d poliovirus RNAs, we have demonstrated that genetic recombination can occur in a cell-free system th

144 Genetic recombination catalyzed by lambda's Red pathway

145 zing radiation-associated phenomena, namely, genetic recombination, chromosomal translocation, cell i

146 ecause topoisomerase I is thought to promote genetic recombination, competence to enhance topoisomera

147 Genetic recombination contributes to human immunodeficie

148 These results emphasize that genetic recombination could contribute to high-level mul

149 lusion, in all 6 cases studied, there was no genetic recombination detected among HCV quasispecies or

150 Holliday junctions play a central role in genetic recombination, DNA repair and other cellular pro

151 id exchange reaction is a common feature for genetic recombination, DNA replication and transcription

152 smatch repair system is the major barrier to genetic recombination during interspecific sexual conjug

153 termed hot spots, are predisposed to undergo genetic recombination during meiosis at higher levels re

154 In mammals, genetic recombination during meiosis is limited to a set

155 Reduction in chromosome number and genetic recombination during meiosis require the prior a

156 variation generated by frequent mutation and genetic recombination during reverse transcription.

157 Genetic recombination ensures proper chromosome segregat

158 genome triplication event, and the rates of genetic recombination estimated/deduced by the compariso

159 In bacteriophage T4, homologous genetic recombination events are catalyzed by a presynap

160 Genetic recombination events in the pathogen can generat

161 bufavirus 1 might have arisen from multiple genetic recombination events.

162 olliday-type junctions formed during in vivo genetic recombination events.

163 increased heterozygosity is preserved after genetic recombination following periods of sexual reprod

164 CTG.CAG sequences, multiple fold expansions, genetic recombination, formation of new recombinant DNA

165 new recombination map for future studies of genetic recombination, genome stability and evolution.

166 of LTR-RTs in relation to the rates of local genetic recombination (GR) and gene densities in the ric

167 spective, and while it retains similarities, genetic recombination guarantees diversity so that we do

168 Genetic recombination has been considered a driving forc

169 While reduced genetic recombination has been demonstrated in maternal

170 Altered genetic recombination has been identified as the first m

171 f the Holliday junction (HJ) intermediate in genetic recombination has been prepared and analyzed in-

172 he Drosophila genome that have low levels of genetic recombination helps us understand the prevalence

173 Viral genetic recombination helps viruses in an evolutionary a

174 Srs2 is known to suppress inappropriate genetic recombination; however, the TNR expansion phenot

175 Genetic recombination impacts on neisserial biology in t

176 Genetic recombination in bacteria is facilitated by the

177 stability can lead to increased frequency of genetic recombination in bacterial genomes.

178 ed within or close to AU-rich regions during genetic recombination in brome mosaic bromovirus (BMV).

179 system, MerCreMer (MCM), was used to induce genetic recombination in cardiac myocytes, which led to

180 c DNA double-stranded breaks (DSBs) initiate genetic recombination in discrete areas of the genome ca

181 Genetic recombination in Escherichia coli is stimulated

182 inally proposed by Robin Holliday to explain genetic recombination in fungi, now appears to be a pivo

183 contrast to the higher-than-average rate of genetic recombination in gene-rich telomeric region on H

184 fer during reverse transcription can produce genetic recombination in human immunodeficiency virus ty

185 it possible to investigate the mechanisms of genetic recombination in mammals in greater detail than

186 es in proximity over a long range, promoting genetic recombination in numerous hot spots.

187 Genetic recombination in single-strand, positive-sense R

188 gs are consistent with a role for suppressed genetic recombination in speciation of A. gambiae.

189 particular to discovering and characterizing genetic recombination in T4, to redefining the nature of

190 lato species was consistent with a role for genetic recombination in the generation of dbpA diversit

191 A prerequisite to genetic recombination in the T4 bacteriophage is the for

192 nase, it promotes repair of dsDNA breaks and genetic recombination in the vicinity of chi recombinati

193 ther lesions in DNA can stimulate homologous genetic recombination in two quite different ways: by pr

194 hetic errors generated during replication or genetic recombination in virtually all organisms.

195 tituted for isoleucine-225, is defective for genetic recombination in vivo and for DNA strand exchang

196 opoisomerases may either promote or suppress genetic recombination in vivo.

197 insights into how a gain of function through genetic recombination, in particular cross-order recombi

198 Genetic recombination increases diversity in HIV-1 popul

199 first evidence of error-prone DNA repair and genetic recombination induced by DNA damage in an archae

200 n (4H) DNA, an in vitro mimic of the in vivo genetic recombination intermediate known as the Holliday

201 Genetic recombination involves either the homo-logous ex

202 The process of genetic recombination involves the formation of branched

203 We hypothesize that this high frequency of genetic recombination is a common feature of primate len

204 Genetic recombination is a critical cellular process tha

205 nary significance of sexual reproduction and genetic recombination is a long-standing puzzle.

206 Genetic recombination is a major force driving the evolu

207 Genetic recombination is a robust mechanism for expandin

208 Drosophila and humans indicate that aberrant genetic recombination is an important component of nondi

209 Genetic recombination is believed to assist HIV-1 divers

210 Genetic recombination is generally evenly distributed al

211 Genetic recombination is largely confined to about one-t

212 In many organisms, the rate of genetic recombination is not uniform along the length of

213 bacteria, the primary function of homologous genetic recombination is the repair of stalled or collap

214 Genetic recombination is usually considered to facilitat

215 icipates in DNA replication, DNA repair, and genetic recombination; it is the most extensively studie

216 Thus, an understanding of the genetic recombination landscape across the maize (Zea ma

217 hort-term evolutionary advantages, a lack of genetic recombination leads to the accumulation over tim

218 c ortholog pairs, the possibility of unequal genetic recombination makes the assignments inconclusive

219 We report a genetic recombination map for Sorghum of 2512 loci space

220 Genetic recombination may play a role in B. burgdorferi

221 d gelonin, via both chemical conjugation and genetic recombination methods, with low molecular weight

222 st partially explain the higher frequency of genetic recombination observed for human immunodeficienc

223 the interaction between mismatch repair and genetic recombination observed in genetic studies.

224 This cloning by genetic recombination obviates the need for ligations or

225 Genetic recombination occurs between homologous DNA mole

226 Genetic recombination occurs during meiosis, the key dev

227 Genetic recombination occurs in all organisms and is vit

228 Genetic recombination of plus-strand RNA viruses is an i

229 gical role, e.g., in nucleosome positioning, genetic recombination, or chromosome superfolding.

230 structure that occurs as an intermediate in genetic recombination pathways, including site-specific

231 nome and to synthesize DNA in DNA repair and genetic recombination pathways.

232 ral decades, research into the mechanisms of genetic recombination proceeded without a complete under

233 Genetic recombination provides an important mechanism fo

234 The variation of genetic recombination rate along a chromosomal arm is sh

235 cated that the protein is mainly involved in genetic recombination rather than DNA repair.

236 To better understand the genetic recombination related with the acquisition of dr

237 critically important molecular mechanism is genetic recombination, required for the beneficial reass

238 r that the population is undergoing frequent genetic recombination, resulting in a mosaic genome pool

239 The strain was constructed by serial genetic recombination steps, but the underlying sequence

240 do this, we used an inducible Cre-dependent genetic recombination strategy to delete ENaC function a

241 itrate reductase (SNaR) that was produced by genetic recombination techniques.

242 four-stranded DNA structure is a key step in genetic recombination that affects the extent of genetic

243 RuvB is a bacterial protein involved in genetic recombination that bears structural similarity t

244 iday junction is a prominent intermediate in genetic recombination that consists of four double helic

245 ss switch in B lymphocytes involves a unique genetic recombination that fuses specific regions within

246 se that these boundary sequences are foci of genetic recombination that serve to assort the modules a

247 Through genetic recombination, the adaptive immune system genera

248 Through genetic recombination, there is fundamentally no limit t

249 RecA is a key protein linking genetic recombination to DNA replication and repair in b

250 s varied independently of each other, but no genetic recombination was detected in a study of 40 huma

251 apospory-specific genomic region in which no genetic recombination was detected.

252 nce DNA TE insertions and the rates of local genetic recombination was detected.

253 dreich's ataxia, respectively) can expand by genetic recombination, we investigated the capacity of t

254 teractions, including viral interference and genetic recombination, which cannot be studied in infect

255 Genetic recombination, which provides a physical connect

256 etic analysis did not reveal any evidence of genetic recombination with either HTLV-1, HTLV-2, or STL

257 xtensive DNA replication can be triggered by genetic recombination, with assembly of a replication co