1 formulate and quantify general mechanisms of
genetic suppression.
2 at are involved in allosteric regulation and
genetic suppression.
3 Our systems also permitted
genetic suppression analysis and revealed that targets o
4 Thus our
genetic suppression analysis uncovers a previously unapp
5 eacetylase complex, show the same pattern of
genetic suppression,
and this suppression pattern differ
6 We have developed a new
genetic suppression assay to investigate the in vivo rol
7 Using a previously characterized branch site
genetic suppression assay, we generated second-site muta
8 dent splicing when coexpressed in an in vivo
genetic suppression assay.
9 Genetic suppression by mutations in MTH1 is likely to be
10 hese studies provide the first evidence that
genetic suppression can occur by providing critical biol
11 Genetic suppression data implicate the essential flankin
12 Analyses of over 10,000 putative
genetic suppression elements (GSEs) sequences revealed c
13 Using
genetic suppression experiments in human cells, we now d
14 wi/Snf is required for Mediator binding, and
genetic suppression experiments suggest that Swi/Snf and
15 ny mechanisms that explain the phenomenon of
genetic suppression have been described, but the wide va
16 cting results, whereas cellular models using
genetic suppression have precluded in vivo confirmation.
17 Surprisingly, little is known about
genetic suppression in archaea, and there has been no ch
18 This
genetic suppression is consistent with a role for APP in
19 The possible mechanism of the observed
genetic suppression is discussed.
20 ak direct physical interaction, although the
genetic suppression is not explained by simple changes i
21 This novel form of
genetic suppression may extend to other genes, pathways
22 The
genetic suppression observed when the FACT defect is com
23 Genetic suppression occurs when the phenotypic defects c
24 signalling by pharmacological inhibition or
genetic suppression of 'canonical' Notch/CSL/MAML1-depen
25 We have previously reported
genetic suppression of a strong hypomorphic allele, vibr
26 -overexpression of eIF1 or eIF5 reverses the
genetic suppression of an eIF4G HEAT domain Ts(-) mutati
27 These include
genetic suppression of an ionic current, embryonic as we
28 Genetic suppression of an N-terminal mutation in the Tyr
29 Strikingly, however,
genetic suppression of apoptosis in the Apaf1 mutant did
30 vation of mTOR with aa supplementation or by
genetic suppression of autophagic activation.
31 activated and released into the cytosol and
genetic suppression of caspase 4, cathepsin B, or apopto
32 Finally,
genetic suppression of dLipin rescues dTorsin-KO defects
33 This is in contrast with the
genetic suppression of EGFR* induction that led to signi
34 PP2 cause the same functional deficit as the
genetic suppression of enzyme expression.
35 Either
genetic suppression of EPAC1 or its pharmacologic inhibi
36 al LTD and is attenuated by pharmacologic or
genetic suppression of GSK-3beta.
37 Genetic suppression of Hrd1 function in DCs protected mi
38 ological pacemakers were recently created by
genetic suppression of inward rectifier potassium curren
39 d apoptosis were significantly suppressed by
genetic suppression of JNK activation.
40 armacologic inhibition (SP600125) as well as
genetic suppression of JNK activation.
41 Genetic suppression of KiSS1 in CDDP-sensitive cell line
42 atory T cells by pharmacological blockade or
genetic suppression of Kv1.3 might be beneficial for the
43 trategies including salicylate treatment and
genetic suppression of myeloid NF-kappaB signaling that
44 Genetic suppression of N-acetyl-l-aspartate (NAA) synthe
45 Genetic suppression of N-cadherin function interferes wi
46 Genetic suppression of NCX reduces both EADs and DADs.
47 In this model
genetic suppression of NRAS(V12) expression results in r
48 Further, pharmacologic or
genetic suppression of p38 MAPK activity, the latter ach
49 L-1R antagonist inhibition, pharmacologic or
genetic suppression of pro-IL-1beta processing to active
50 We further demonstrate that
genetic suppression of Src regulates the activity of the
51 Genetic suppression of Tam3 transposition, using the STA
52 elatonin agonist, ramelteon, phenocopies the
genetic suppression of the Clock mutant phenotype observ
53 We hypothesized that
genetic suppression of the L-type calcium channel access
54 Genetic suppression of the metacaspase-autophagy pathway
55 on was further supported by the finding that
genetic suppression of the Toll/Dif and Imd/Relish infla
56 Genetic suppression of the type III blockade does not, h
57 Genetic suppression of these unc-86/VP16 phenotypes may
58 Pharmacological or
genetic suppression of UBA1 was sufficient to recapitula
59 Genetic suppression or pharmacological inhibition of thi
60 This
genetic suppression profile is similar to that of sec35-
61 This
genetic suppression provides compelling evidence that AP
62 Genetic suppression revealed that this synthetic lethali
63 iously identified substrate of Highwire, and
genetic suppression studies show that Wallenda/DLK is re
64 Genetic suppression studies using matrix metalloproteina
65 To examine the basis of
genetic suppression,
we cloned, purified, and tested Fli
66 To explore the principles of
genetic suppression,
we examined both literature-curated
67 with the osmotic stabilizer sorbitol or via
genetic suppression with the kre5(W1166X) mutant.