ライフサイエンスコーパス: genetically modified mice

1 elicited humoral responses in MV-susceptible genetically modified mice.

2 or the dominant nature of FHHt in humans and genetically modified mice.

3 uitable test for species-typical behavior in genetically modified mice.

4 article, we will highlight recent data from genetically modified mice.

5 o JNK inhibition or activation in vivo using genetically modified mice.

6 d depression-related behaviors in normal and genetically modified mice.

7 etermined by comparison of the phenotypes of genetically modified mice.

8 chanisms of graft injury and regeneration in genetically modified mice.

9 periments using LAT-deficient cell lines and genetically modified mice.

10 r assessing learning and memory abilities in genetically modified mice.

11 ospholamban and the ryanodine receptor using genetically modified mice.

12 edative effects of ethanol in three lines of genetically modified mice.

13 emia has been greatly enhanced by the use of genetically modified mice.

14 sion in the myocardium of both wild-type and genetically modified mice.

15 Wild type and genetically modified mice.

16 central to the cardiovascular phenotyping of genetically modified mice.

17 gic asthma model in ATX-LPA pathway-specific genetically modified mice.

18 pendent on Rab27B, as shown using acini from genetically modified mice.

19 ic smooth muscle causes thoracic aneurysm in genetically modified mice.

20 d crypt epithelia of intestinal tissues), in genetically modified mice.

21 es to inflammatory sites was investigated in genetically modified mice.

22 actor (GM-CSF) signaling based on studies in genetically modified mice.

23 erefore investigated potential mechanisms in genetically modified mice.

24 evelopmental changes in the barrel cortex of genetically modified mice.

25 ssection of placental transfer mechanisms in genetically modified mice.

26 We created genetically modified mice (alpha1 H101R) with a diazepam

27 from studies utilizing rapamycin, studies in genetically modified mice also suggest that mTOR couples

28 first targeting of the dorsal hippocampus in genetically modified mice and confirm a role for CREB in

29 Mechanistic studies were carried out using genetically modified mice and depletion of lymphocyte su

30 Recent studies using genetically modified mice and electrophysiological recor

31 Evidence is reviewed from genetically modified mice and human biomarker and geneti

32 The study of genetically modified mice and improvements in the in-vit

33 Observations in genetically modified mice and in humans with mutations i

34 Analyses of genetically modified mice and in vitro and in vivo precl

35 ent studies using the EL4 model with various genetically modified mice and macrophage-depleted mice r

36 Here, we used genetically modified mice and molecular imaging to test

37 nation of intravital multiphoton microscopy, genetically modified mice and novel in vivo homing assay

38 Studies of genetically modified mice and of molecular pathways in a

39 amined the time course of colonization using genetically modified mice and pneumococci.

40 he value of screening platelet phenotypes of genetically modified mice and shed further light upon th

41 flammation and OSM-induced fibrosis, we used genetically modified mice and show that the fibrotic res

42 Using genetically modified mice and time-lapse video recording

43 d Tbx1 function during OFT development using genetically modified mice and tissue-specific deletion,

44 By analyzing cell lines, genetically modified mice, and HCC tissues, we found tha

45 ide) in genetically distinct inbred strains, genetically modified mice, and outbred mice.

46 The two colonies of genetically modified mice-and, for purposes of controls,

47 retinol formation in the different types of genetically modified mice are in reasonable agreement wi

48 ic stem (ES) cells have been used to produce genetically modified mice as experimental models of huma

49 Findings from genetically modified mice as well as pharmacological stu

50 n gene-related peptide were also examined in genetically modified mice (BDNF(+/-)) with reduced level

51 , and rhodopsin kinase-deficient mice and in genetically modified mice containing unpalmitylated rhod

52 ears have seen an explosion in the number of genetically modified mice created to aid understanding o

53 rally available non-peptidic antagonists and genetically modified mice deficient in B(1) receptor exp

54 Consistent with the human data, the genetically modified mice displayed significantly more e

55 Here we show that in genetically modified mice, disrupting the recruitment of

56 ta might be particularly useful in assessing genetically modified mice, even in laboratories not prim

57 In conclusion, Folbp1 and RFC1 genetically modified mice exhibit distinct changes in co

58 We found that genetically modified mice expressing low levels of tissu

59 generation failure that have been made using genetically modified mice, focusing on the inhibitory in

60 annulating collecting lymphatic vessels from genetically modified mice for ex vivo study.

61 One of the major limitations in the use of genetically modified mice for studying cognitive functio

62 We used genetically modified mice (germline Npy, Y1, and Y2 rece

63 The use of genetically modified mice has been an important model sy

64 Sharp tuning in genetically modified mice has been attributed to decreas

65 The availability of genetically modified mice has prompted the adaptation of

66 Genetically modified mice have been extensively used for

67 Studies in genetically modified mice have demonstrated that neuregu

68 t encode spatial location -in freely moving, genetically modified mice have further advanced our unde

69 Although genetically modified mice have provided a great understa

70 Recent studies using genetically modified mice have provided important new in

71 nd-healing assay was performed in 3 types of genetically modified mice having various Nur77 activitie

72 BP in drug-induced plasticity using CBP-FLOX genetically modified mice in combination with adeno-asso

73 We used HDAC3-FLOX genetically modified mice in combination with adeno-asso

74 To permit the use of these (and other) genetically modified mice in the analysis of venous inju

75 Here we describe compound genetically modified mice in which expression of the end

76 onductances unique to sour cells, we created genetically modified mice in which sour cells were marke

77 ADAR2 protein expression, we have generated genetically modified mice in which the ability of ADAR2

78 is was confirmed by experiments performed in genetically modified mice in which the alpha1 subunit ha

79 We intended to address this question using genetically modified mice in which the expression of a s

80 cytes freshly isolated from adult rabbits or genetically modified mice, in combination with pharmacol

81 al, high-frequency region of the cochleae of genetically modified mice (including models of human her

82 distribution of blood flow in the hearts of genetically modified mice is a phenotype of interest bec

83 that, as illustrated here, the real value of genetically modified mice is not as 'models of schizophr

84 When this technique is applied in genetically modified mice, it enables the investigator t

85 he latter fluorescence was absent in eyes of genetically modified mice lacking a functional visual cy

86 Here we show that genetically modified mice lacking beta1 integrins in the

87 Here, we have used tissue from genetically modified mice lacking functional COX-1 (COX-

88 In particular, screening of genetically modified mice lacking individual GRKs or bet

89 Moreover, findings in genetically modified mice lacking macrophages have confi

90 in organotypic hippocampal slices taken from genetically modified mice lacking the GluA1 subunit.

91 Genetically modified mice lacking the glutamate receptor

92 Consistently, NGAL deficiency in genetically modified mice leads to an increased growth o

93 we used both pharmacological inhibitors and genetically modified mice models to investigate the iden

94 X(2) receptors based on studies conducted on genetically modified mice needs to be viewed with cautio

95 ibroblast-cholangiocyte coculture system and genetically modified mice, Omenetti and colleagues prese

96 The study of renal miRNAs, using genetically modified mice or by perturbing endogenous mi

97 te the apparent dominant role of ADAMTS-5 in genetically modified mice, our data suggest that both AD

98 Studies employing genetically modified mice point to Hif-2alpha, one of tw

99 pectroscopy in perfused hearts isolated from genetically modified mice (PPARalpha(-/-)) that mimic th

100 Recent studies with genetically modified mice provide important new insights

101 escent imaging of kidney sections from these genetically modified mice revealed that RhoA and AQP2 ac

102 Genetically modified mice shed new light on how ketamine

103 Studies using genetically modified mice suggest that Galpha q mediates

104 Work with genetically modified mice suggests that the viral latent

105 shown in an animal model: F-araAMP protected genetically modified mice susceptible to MV infection fr

106 vations, altogether with those obtained from genetically modified mice targeting individual CRMPs and

107 f CD103(+) DCs in cGN using several lines of genetically modified mice that allowed us to reduce the

108 ible to follow new blood vessel formation in genetically modified mice that are perinatally lethal.

109 In this study, we have created genetically modified mice that conditionally express Ht3

110 Using genetically modified mice that conditionally expressed g

111 egment is known as the M1' domain, and using genetically modified mice that contain the human M1' dom

112 er, irradiation, or thymectomy, we developed genetically modified mice that express diphtheria toxin

113 he same disorder, achalasia, was observed in genetically modified mice that express full-length farne

114 Although genetically modified mice that lack receptors for either

115 rally evoked symptoms is based on studies on genetically modified mice, the cellular localization of

116 By using novel genetically modified mice, the current study showed that

117 tor complex has been enriched by analyses of genetically modified mice; these analyses have uncovered

118 tralizing antibodies or T cells derived from genetically modified mice, TL1A inhibition of Th17 devel

119 In this work, we used genetically modified mice to allow conditional expressio

120 We also used genetically modified mice to define the roles of Chi3l1

121 For the current study we utilized genetically modified mice to delineate the relative cont

122 To explore the nature of this deficit, we genetically modified mice to model the increase in stria

123 In this study, we used genetically modified mice to study the light responses a

124 Implications for studies involving genetically modified mice treated with topical agents an

125 Using genetically modified mice, we addressed the contribution

126 By introducing this system into genetically modified mice, we can readily manipulate the

127 Using genetically modified mice, we demonstrate that premature

128 onsistent with this information derived from genetically modified mice, we demonstrated that neutrali

129 During our examination of genetically modified mice, we discovered a series of pro

130 Because those studies were performed on genetically modified mice, we examined whether neutraliz

131 Using genetically modified mice, we found that imiquimod-induc

132 Using genetically modified mice, we found that loss of Id1 inh

133 Using male CaMKIV genetically modified mice, we found that nicotine reward

134 Using genetically modified mice, we have shown that renal phos

135 Using a combination of genetically modified mice, we show that the coordinated

136 Using genetically modified mice, we systematically examined th

137 Genetically modified mice were developed to selectively

138 L-10(-/-)) mice and several other strains of genetically modified mice were generated and used.

139 Studies with genetically modified mice were performed.

140 es, and electrophysiological recordings from genetically modified mice were used to show that WAVE-1

141 ugs acting on the endocannabinoid system and genetically modified mice were used.

142 ssection of the immune response to HBV using genetically modified mice whose immunoregulatory and imm

143 In genetically modified mice with a 50% reduction in liver

144 Genetically modified mice with approximately 10% of the

145 We then show that genetically modified mice with CARMA3-deficient AECs hav

146 Properties were evaluated in genetically modified mice with differing levels of TGF-b

147 Immunization of MV-susceptible, genetically modified mice with either vector induced neu

148 abnormal muscular septum, which phenocopied genetically modified mice with elevated BMP10 levels.

149 ffect of FoxO6 on hepatic gluconeogenesis in genetically modified mice with FoxO6 gain- versus loss-o

150 In genetically modified mice with low tissue factor activit

151 Using genetically modified mice with lung-specific inducible (

152 In genetically modified mice with reduced catechol-O-methyl

153 r phenotype of liver damage than those using genetically modified mice, with the exception of the chr

154 tes in regulating intact FGF23 production in genetically modified mice without and with adenine-induc