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1 was detected, indicating a limited effect of genetics.
2 jor landmarks of late 20th century molecular genetics.
3 asets is central in facilitating advances in genetics.
4 y, is a fundamental quantity in evolutionary genetics.
5 ons plays a fundamental role in evolutionary genetics.
6 ve traits (QTs) is one major task in imaging genetics.
7 nsertion collection with traditional forward genetics.
8 functions via peptide treatment and reverse genetics.
9 ging from disease gene mapping to speciation genetics.
10 All constructs were recovered by reverse genetics.
11 story, genealogy, forensics and male medical genetics.
12 ime pointing to remarkable complexity in CHD genetics.
13 It is an important concept in breeding and genetics.
14 T and CD8(+) T cells are more influenced by genetics.
15 stress is known to be influenced by sex and genetics.
16 endelian disease is a major unknown in human genetics.
17 the etiology of Alzheimer's disease by human genetics.
18 experiments to solve a difficult problem in genetics.
19 Yeast is a powerful model for systems genetics.
27 Neuron, Cho et al. (2017) use advanced mouse genetics and biochemical experiments to unravel the liga
29 had an exceptional impact on fields such as genetics and cancerous mutation detection Here we report
31 ion, land-use and habitat surveys, molecular genetics and demographic and spatial modelling to analys
32 These findings demonstrate that both host genetics and diet can influence the microbial communitie
33 rical perspective on the progress made in MS genetics and discuss current work geared towards creatin
34 monstrates the complementarity of population genetics and ecological niche modeling in understanding
35 data sets: the Epidemiological Study on the Genetics and Environment of Asthma (EGEA) data set (1660
36 ts of the EGEA (Epidemiological study of the Genetics and Environment of Asthma, bronchial hyperrespo
37 Although leukocyte subsets are influenced by genetics and environment, adaptive immune traits are mor
40 us be used to rapidly take a snapshot of the genetics and epigenetics of each specific human centrome
41 owever, little is known about the population genetics and evolutionary forces underlying the invasive
42 In 2015, the American College of Medical Genetics and Genomics (ACMG) and the Association for Mol
43 dge on disease aetiopathogenesis and outline genetics and genomics approaches that are helping cataly
47 rsity Resource (CeNDR) to enable statistical genetics and genomics studies of C. elegans and to conne
48 practical prospects for the use of landscape genetics and genomics to understand the biology and cont
51 Growing availability of data on pathogen genetics and human ecology, coupled with computational a
52 ne essentiality has applications in clinical genetics and may offer insights for drug development.
53 autoimmune diseases for which the underlying genetics and mechanisms are not yet fully understood.
56 We critically review progress in imaging genetics and offer suggestions and highlight potential p
57 ators of these 150 genes, so we used reverse genetics and pharmacologic methods to explore regulation
60 conducted to evaluate distribution, ecology, genetics and secondary chemistry to shed light on factor
63 e clearance, whereas patients with high-risk genetics and T-cell acute lymphoblastic leukemia respond
64 ng the mechanisms that link 1-carbon pathway genetics and the condition that we suggest calling, "ast
66 enrolled in the Childhood Autism Risks from Genetics and the Environment (CHARGE) case-control study
67 eractions and is thus dependent on both host genetics and the extent of virus-mediated HLA-C downregu
68 cal advancements in fields such as molecular genetics and the human microbiome have resulted in an un
69 (2017) examine the relationship between host genetics and the oral microbiome in the context of healt
70 ssible to begin to understand the underlying genetics and to use the new information to begin the eff
71 hlighting the interplay between epigenetics, genetics, and cell-to-cell signaling in cancer, with par
72 antifies the respective effects of age, sex, genetics, and cellular heterogeneity on the interindivid
73 enotype, biological properties, epigenetics, genetics, and clinical associations of human AML LSCs an
75 results from grain quality genomics, systems genetics, and digestibility phenotyping, we propose targ
76 causatively linked to environmental stimuli, genetics, and infection, and a critical current target f
77 of modern chemistry, biochemistry, molecular genetics, and optical physics to these old structures en
78 H9 virus replication was observed by reverse genetics, and recombinant H9N2 viruses with amino acids
79 used to study differential effects of media, genetics, and stress on microbial population growth.
89 ctories and (ii) use quantitative population genetics approaches to estimate the contribution of sele
90 udies in humans and mice, -omics and systems genetics approaches, and unique experimental mouse model
91 cattle genomes and eventually inform future genetics-assisted livestock breeding programs in Russia
92 he phenotypic characteristics and underlying genetics associated with amelanotic melanoma are unknown
95 Thus, testing for BRAF-V600E allows for a genetics-based differential diagnosis between HCL and HC
98 effort, leveraging diverse disciplines (from genetics, biochemistry, and immunology to mathematics, c
99 tive Medicine, Asia Pacific Society of Human Genetics, British Society for Genetic Medicine, Human Ge
100 of the pollen season are governed by species genetics, but plant phenology is also influenced by clim
101 ew findings demonstrating that developmental genetics can be used to identify populations of neurons
104 laboratory mice have demonstrated that host genetics can influence microbial community structure, bu
106 ta-analysis Plus the Coronary Artery Disease Genetics (CardiogramplusC4D) consortium's 1000 genomes-b
108 s "the stem cell of biological disciplines." Genetics, cell biology, oncology, immunology, evolutiona
110 rom the Tourette International Collaborative Genetics cohort and a replication sample of 186 trios fr
111 GRAM] plus The Coronary Artery Disease [C4D] Genetics; combined total 66 842 cases), stroke from META
112 e broader functional genomics and population genetics communities, we developed SNPDelScore, which us
114 53 CN controls) from the Alzheimer's Disease Genetics Consortium (ADGC), a National Institute on Agin
115 rols from Phase 1 of the Alzheimer's Disease Genetics Consortium (ADGC), providing a polygenic hazard
117 al FTD Genomics Consortium, International PD Genetics Consortium and International Genomics of AD Pro
118 mewide association data from the Tobacco And Genetics Consortium and Psychiatric Genomics Consortium.
119 European individuals from the Global Lipids Genetics Consortium in a trans-ancestry meta-analysis.
121 ing in songbirds to study how experience and genetics contribute to interindividual differences in le
123 g high-resolution approaches combining mouse genetics, designer receptor exclusively activated by des
124 play in depression may benefit from focus on genetics discovered for putative protective factors.
125 cientific advances in the research fields of genetics, disease modelling, biomarkers, and therapeutic
126 mall genome (approximately 800 Mbp), diploid genetics, diverse germplasm, and colinearity with other
127 genetic basis and guide best practices for a genetics-driven approach to early intervention in at-ris
128 milial, has a genetic basis, in which case a genetics-driven approach to identifying at-risk family m
130 sification system, histopathology, molecular genetics, electrophysiology, and transcriptome and cell
133 onment and dynamic interactions between host genetics, environmental factors, and microbes in shaping
136 integrative approach combining quantitative genetics, expression and diversity data permitted develo
139 specialization of EV-releasing neurons using genetics, fluorescence microscopy, kymography, electron
140 hnology is widely used in the field of mouse genetics for spatial and/or temporal regulation of gene
141 eates a direct phenotypic link between human genetics (G versus A alleles cause Cys529 versus Tyr529
143 rdinary advances in our understanding of the genetics, genomics, biochemistry, and signal diversity o
144 approaches from movement ecology, landscape genetics/genomics and ecoimmunology may provide new aven
151 roimaging, neuropathology, epidemiology, and genetics have led to a deeper understanding of how vascu
152 rable advances in the understanding of their genetics have led to increased clinical recognition of t
155 This study sought to further explore the genetics in a larger set of patients following-up on the
158 the potential for GWA to complement forward genetics in identifying the genetic basis of ecologicall
159 237 lung cancer cases in the Environment And Genetics in Lung cancer Etiology study, using the Infini
161 ches followed by drug optimization, chemical genetics in plant systems tends to be fueled by more gen
162 overview of the current progress in chemical genetics in plants, with a focus on the discoveries rega
163 ed in vitro models to study the role of host genetics in the response of macrophages to this obligate
166 but little is known about how experience and genetics interact to determine complex learned phenotype
172 al WES referral tests (N=6517, Baylor Miraca Genetics Laboratories) and compared with a control cohor
173 in the fields of archaeology and population genetics lack either temporal resolution or formal quant
174 is a multifactorial condition influenced by genetics, lifestyle, and environment.We investigated whe
175 he proposed approach contributes to both the genetics literature and the statistics literature, and h
176 workshop assembled international experts in genetics, medical and gynecologic oncology, clinical psy
179 ts of protein dynamics with loss-of-function genetics, mosaic analysis, and temporal control of gene
180 g this hypothesis will help characterize the genetics of 1-carbon pathway metabolism, homocysteine, o
181 develop a discrete time model for population genetics of a drive and proposed genetic countermeasures
182 es drawn from the Collaborative Study on the Genetics of Alcoholism (COGA), we performed a genome-wid
184 es a more comprehensive understanding of the genetics of alcoholism than previous case-control studie
185 of the incidence, prevalence, phenotype and genetics of ALS and outline the core operating principle
187 of the current study was to investigate the genetics of antibody responses to an acellular pertussis
188 P1 haplotypes imputed from the International Genetics of AS Consortium (IGAS) Immunochip study were a
189 tudies of Hispanic children: the Puerto Rico Genetics of Asthma and Lifestyle Study (PR-GOAL; n = 306
191 was to gain new insights into the underlying genetics of body fat distribution by conducting sample-s
192 ans have provided numerous insights into the genetics of both gene expression and complex diseases.
196 nalysis between longitudinal cohort GoDARTS (Genetics of Diabetes Audit and Research, Tayside Scotlan
197 lected as part of the Yale-Penn study of the genetics of drug and alcohol dependence from February 14
198 pand upon current perspectives regarding the genetics of FA, indicating that FA plays a role in a myr
202 demonstrates the importance of studying the genetics of IBD and other complex diseases in population
203 Our findings provide new insight into the genetics of lean body mass.Lean body mass is a highly he
204 This review discusses the discovery and genetics of LOX-1; describes existing evidence supportin
206 dvance in our understanding of the molecular genetics of NCMD and provide insights into the genetic p
207 These data provide new insight into the genetics of neurocognitive function with relevance to un
208 2, advances in understanding the biology and genetics of non-Hodgkin lymphoma and the availability of
211 We thus characterize here the population genetics of previously inaccessible intestinal microbes,
212 stantially enhanced our understanding of the genetics of primary brain tumors by uncovering several n
216 ensive understanding of the cell biology and genetics of spermatogenesis is difficult for most specie
219 g] will be critical to dissect the molecular genetics of T2DM pathogenesis, to build next-generation
221 escale, evolutionary history, and population genetics of the HIV-1 CRF01_AE strains primarily respons
225 focused review will describe the underlying genetics, pathophysiology, classification and treatment
226 s (e.g., nonhuman animal models, psychiatric genetics, pharmacologic challenge) to elucidate brain-ba
228 al and genetic association studies show that genetics play an important role in the attainment of edu
232 deep metric learning to large-scale chemical genetics projects highlights the utility of this and rel
233 Here, using time-lapse embryonic imaging, genetics, protein-interaction, and functional studies, w
237 e 2 diabetes mellitus from DIAGRAM (Diabetes Genetics Replication and Meta-analysis; 34 840 cases), a
238 a cancer therapy, efficient reovirus reverse genetics rescue will accelerate production of recombinan
240 he importance of including AA populations in genetics research on SUDs and the utility of the endophe
241 f the largest ASD family cohorts, the Autism Genetics Resource Exchange and Autism Genome Project (AG
242 2A E181A mutations into VHSV-IVb via reverse genetics resulted in viruses that replicated efficiently
243 oceanica (NoDGAT2s or NoDGTTs), via reverse genetics, revealed that NoDGAT2A prefers saturated fatty
244 es of mutant influenza viruses using reverse genetics (RG) and selected resistant variants in the pre
246 ger than 50 years, evaluated by the clinical genetics service at a single tertiary care cancer center
247 outpatient clinics of the Victorian Clinical Genetics Services at the Royal Children's Hospital, Melb
250 is a user-friendly and efficient population genetics simulator that handles complex evolutionary and
253 British Society for Genetic Medicine, Human Genetics Society of Australasia, Professional Society of
255 onal importance, no large-scale neuroimaging genetics studies have targeted the contributions of gene
259 and characterization of a novel ZIKV reverse genetics system based on a 2015 isolate from Puerto Rico
262 dy, we employed a helper virus-based reverse genetics system to identify NSP2 gene regions that corre
266 sources of heterogeneity within psychiatric genetics that can obscure the identification of genotypi
267 ogy, proteomics, genomics, cell biology, and genetics that have propelled new discoveries in the fiel
268 ichment, bioinformatics analysis and reverse genetics that these RNA segments are bound to the coat p
269 facilitated in population and complex-trait genetics, the biology of diseases, and translation towar
270 such as the ENIGMA (Enhancing Neuro Imaging Genetics through Meta Analysis) consortium are beginning
273 mics Consortium (PGC)-Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) PTSD Working Gro
274 study by the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Major Depressive Disorde
275 To understand better the contribution of genetics to CKD progression, we performed a genome-wide
279 Application of the principles of population genetics to the HLA genes has resulted in the developmen
280 y and Kinship Toolkit (AKT) is a statistical genetics tool for analysing large cohorts of whole-genom
282 e outside the scope of his work, even though genetics was a growing discipline at the time the book w
288 patibility complex-linked systemic sclerosis genetics, we performed genotyping of major histocompatib
292 clinical trials, diagnosis, management, and genetics were retrieved (reviews, guidelines, clinical t
295 adaptive immune traits are more affected by genetics, whereas innate immune traits are more affected
296 ine this question by intergrating population genetics with ecological niche modelling of Litsea auric
297 has been made in ecological and evolutionary genetics with studies demonstrating how genes underlying
298 and function, combining versatile Drosophila genetics with superresolution microscopy and various fun
299 combines Drosophila melanogaster (fruit fly) genetics with transcriptome analyses it was found that t
300 mber of open questions in human evolutionary genetics would become tractable if we were able to direc
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