ライフサイエンスコーパス: genogroup

1 e level, that comprise a single genotype and genogroup.

2 s comprising two clusters within a third NLV genogroup.

3 cies now called the Ehrlichia phagocytophila genogroup.

4 cificity of each IgM test for its respective genogroup.

5 d to members of the Ehrlichia phagocytophila genogroup.

6 nd are likely members of a new mamastrovirus genogroup.

7 e NoV NS3 proteins among the seven Norovirus genogroups.

8 that were conserved within genoclusters and genogroups.

9 capsid protein sequences, and comprise three genogroups.

10 the clinical isolates were placed into three genogroups.

11 acted more strongly than did strains between genogroups.

12 the VP6 amplicons revealed two clusters, or genogroups.

13 The clinical isolates clustered into 21 genogroups.

14 cific cleavage sites both within and between genogroups.

15 ding specificities of noroviruses from other genogroups.

16 519-527)]) was highly conserved among all NV genogroups.

17 in that is highly conserved across norovirus genogroups.

18 omobacter species and revealed 14 additional genogroups.

19 NV2461 was found to occur in the majority of genogroup 1 (G1) but not genogroup 2 (G2) "Norwalk-like

20 ) infections were 3 times more frequent than genogroup 1 (GI) infections.

21 , we report the first complete sequence of a genogroup 1 avian bornavirus (ABV1).

22 Furthermore, an anti-genogroup 1 human TTV antiserum did not react with any o

23 gG nor salivary IgA cross-reacted with NV, a genogroup 1 norovirus.

24 36 G1P[8], 18 G3P[8], and 4 G12P[8] Wa-like genogroup 1 strains with VP6-VP1-VP2-VP3-NSP1-NSP2-NSP3-

25 owed that they were human calicivirus (HuCV) genogroup 1 viruses related, but not identical, to NV.

26 rwalk virus, a prototype member of Norovirus genogroup 1.

27 s) correlated with a known species, and nine genogroups (17 strains) did not.

28 in the majority of genogroup 1 (G1) but not genogroup 2 (G2) "Norwalk-like viruses" (NLVs).

29 In multivariate analysis, genogroup 2 genotype 4 (GII.4) NoV strains were associat

30 oss-reactive with Hawaii virus (HV), another genogroup 2 norovirus, salivary IgA was less cross-react

31 challenged with Snow Mountain virus (SMV), a genogroup 2 norovirus.

32 are representative of the genera Norovirus (genogroup 2), Sapovirus, and Vesivirus, respectively.

33 dimerization appears to be unique within the genogroup 2c and may potentially increase the complexity

34 sion following introduction of a full-length genogroup 3 norovirus genome into HepG2 cells.

35 ding frames, a feature that may be unique to genogroup 3 noroviruses.

36 Twelve genogroups (74 strains) correlated with a known species,

37 The prevalence of genogroup A fell from 0.7% to 0.02% in Chad following ma

38 ride capsules; genogroup W predominated, and genogroup A was rare.

39 d (serologically nongroupable); by PCR-based genogrouping, a quarter of these belonged to the capsula

40 tes were also found that corresponded to the genogroup A2 variant identified in New York and Australi

41 linkage disequilibrium in all of the species/genogroups able to be tested, indicating that each group

42 e activity in some individuals but not cross-genogroup activity.

43 d by polymerase chain reaction for norovirus genogroup and genotype.

44 s classified the recovirus isolates into two genogroups and at least four genetic types.

45 me polymerase chain reaction, along with TTV genogroups and coinfection with HEV.

46 protein function within different Norovirus genogroups and expands a growing knowledge base on the i

47 characterized by antigenic variation between genogroups and genotypes and antigenic drift of strains

48 To determine the genogroups and genotypes of bovine enteric caliciviruses

49 The distributions of genogroups and of capsule-null organisms were similar wi

50 ports the subdivision of human NLVs into two genogroups and provides an assay for the rapid identific

51 coinfections with distinct BECV genotypes or genogroups, and describe the first natural BoNV genotype

52 . chaffeensis, each belonging to a different genogroup, are inoculated into severe combined immunodef

53 A potent EV71 genogroup B- and virus-specific ASC response was detecte

54 ovirus, which is comprised of at least three genogroups based on sequence differences.

55 We tentatively classified SaVs into 14 genogroups based on the complete capsid protein VP1.

56 No clear segregation of species/genogroups between CF and non-CF sources was found.

57 However, we found three genogroups by gene sequence analysis.

58 cross-reactive EV71-specific ASC response to genogroup C viral antigens composed about 10% of the res

59 o belong to a novel genogroup of rhinovirus, genogroup C.

60 phages differentiate EHEC O157 isolates into genogroups commonly isolated from cattle but rarely from

61 hly divergent strains suggested that the MNV genogroup comprises a single serotype.

62 he 16S ribosomal DNA (rDNA) of the Ehrlichia genogroup comprising E. equi, E. phagocytophila, and the

63 roduced disease in the SCID mouse model, and genogroup-consistent trends were noted in cytokine produ

64 Our results indicate that hNoVs exhibit genogroup dependent resistance and that disinfection pra

65 Although genogroup-dependent variation in HBGA binding specificit

66 Capsular genogroups detected by broth culture were genogroups W (

67 One MAb had broad cross-genogroup EIA reactivity to a nonblockade, linear, conse

68 two major genogroups (GI and GII), with each genogroup further divided into multiple genotypes.

69 groups (genogroup I [GI] and GII), with each genogroup further divided into several genotypes.

70 ly clonal population, with most belonging to genogroup G1407 and harbouring the penA mosaic gene.

71 Human NoVs are classified into two major genogroups (genogroup I [GI] and GII), with each genogro

72 evivirus), which can be subdivided into four genogroups (genogroups I and II in Levivirus and genogro

73 The concentrations of NoV genogroups (GG) I and II in samples collected at WWTPs a

74 V71 variants have been classified into three genogroups (GgA, GgB, and GgC), and the latter two are f

75 Although designed for NV, a genogroup GI.1 norovirus, NoroGLuc also efficiently dete

76 ction and typing of NoV strains belonging to genogroups GI and GII and adapted them to the LightCycle

77 Structures of noroviruses from genogroups GI and GII in complex with HBGAs, however, re

78 They are classified into two major genogroups (GI and GII), with each genogroup further div

79 variable and have been classified into four genogroups (GI, -II, -IV, and -V).

80 es and one novel cluster (n = 5) within four genogroups (GI, GII, GIV, and GV) were identified by phy

81 m a diaper-changing station in the restroom (genogroup GII).

82 Replication of HuNoV genogroup GII.3 strain U201 RNA, generated from a revers

83 within GII) and SaVs comprising at least two genogroups (GIII and GVI?/JJ681-like) and two unclassifi

84 Most genogroups had consistent biotypes (as determined with t

85 Each genogroup has further diverged into multiple sub-lineage

86 Seven ABV genogroups have been identified worldwide from a variety

87 These results establish NoroGLuc as a pan-genogroup HuNoV protease reporter system that can be use

88 A total of 435 outbreaks (11%) were typed as genogroup I (GI) and 3,525 (89%) as GII noroviruses.

89 mine if virus-like particles (VLPs) of HuNoV genogroup I (GI) and GII bind to A- or H-type tissues; (

90 l studies have shown increased prevalence of genogroup I (GI) NoVs.

91 ifferences within the P2 domain of norovirus genogroup I (GI) strains can be used to segregate outbre

92 ile (12.6 to 13.9% prevalence) and norovirus genogroup I (GI)/GII (5.7 to 13.9% prevalence) were two

93 capsid protein or P domain mutants from both genogroup I (Norwalk virus) and genogroup II (VA387) nor

94 iation was particularly strong for norovirus genogroup I (NoV-GI) and between adult AGI and enterovir

95 li (OR: 1.65; 95% CI: 1.10, 2.46), norovirus genogroup I (OR: 1.66; 95% CI: 1.23, 2.25), and Giardia

96 Vs are classified into two major genogroups (genogroup I [GI] and GII), with each genogroup further d

97 genogroup II (GII) infection was higher than genogroup I and peaked at 6-11 months across sites.

98 hat strain fr should be grouped in Levivirus genogroup I and that the MX1 and M11 strains belong in A

99 Genogroup I comprised the M. szulgai type strain, all th

100 suitable for diagnosis of NV and other HuCV genogroup I infections and is especially useful when ser

101 ve IgM, indicating test specificity for HuCV genogroup I infections.

102 d volunteers and from patients involved in a genogroup I NLV outbreak were also tested.

103 ses to the major capsid protein from another genogroup I NLV strain (NCFL) isolated from a recent out

104 Norwalk virus (NV) is the prototype genogroup I norovirus that specifically recognizes A- an

105 ding Norwalk Virus capsid protein (a related Genogroup I Norovirus) in transiently transfected plants

106 m the N-terminal protein of Norwalk virus (a genogroup I norovirus) or MD145 (a genogroup II noroviru

107 alysis, is highly conserved, but only in the genogroup I noroviruses, suggesting that a mechanism by

108 Sera from genogroup I Norwalk virus (NV)-inoculated volunteers and

109 f the Seto virus (SeV), a Japanese strain of genogroup I Norwalk-like viruses (NLVs), was expressed a

110 ns were the most abundant (79%), followed by genogroup I NoV strains (19%) and sapovirus (2%).

111 oV-positive stool samples were identified as genogroup I NoVs, and time spent at travel destinations

112 In sera from those infected with genogroup I NV or NLVs in volunteer and outbreak studies

113 am were positive for a Norwalk-like virus of genogroup I on RT-PCR assay; the RT-PCR products had ide

114 ontrast to the MSP2 homologues in ehrlichial genogroup I pathogens, Ehrlichia chaffeensis, Ehrlichia

115 V and the prototype human strain 1-CHN-97 of genogroup I PBVs and an even lower similarity (38.4%) to

116 We now report the detection of genogroup I PBVs in 48% (44/92) of the fecal specimens b

117 Although genogroup I strain fr and genogroup III strains MX1 and

118 trains were the predominant type (73%), with genogroup I strains causing 26% of all NLV-positive outb

119 Avidities to heterotypic genogroup I VLPs were not sustained at day 35 after vacc

120 o genetic lineages were distinguished within genogroup I, consisting of strains serologically charact

121 virus-like particles (VLPs) derived from NV (genogroup I, GI) and MD145 (genogroup II, GII) norovirus

122 s on the norovirus capsid protein for both a genogroup I-cross-reactive monoclonal antibody and a gen

123 Although the genogroup I-cross-reactive monoclonal antibody was previ

124 stomach biopsy specimens, as well as that of genogroup I.1 and genogroup II.4 virus-like particles, w

125 ototype norovirus strain Norwalk virus (NV) (genogroup I.1).

126 ression and self-assembly of newly developed genogroup I/II chimeric VLPs showed that five MAbs bound

127 st between proteases from human noroviruses (genogroups I (GI) and II) and the commonly used murine n

128 genogroups, with human strains grouped into genogroups I (GI), II, and IV.

129 g HuNVs of 4 and 10 genetic subgroups within genogroups I and II (GI and GII), respectively, and 39 s

130 e detection and differentiation of norovirus genogroups I and II (GI and GII), which account for the

131 hich can be subdivided into four genogroups (genogroups I and II in Levivirus and genogroups III and

132 Human noroviruses in genogroups I and II interact with histo-blood group anti

133 Six distinct genetic clusters within genogroups I and II of the NLVs were detected; a genogro

134 tide similarities among strains of Levivirus genogroups I and II were 75% to 99% and 83 to 94%, respe

135 ovirus (types 1, 2, 3, 4, and 8), sapovirus (genogroups I and II), parechovirus (types 1, 3, 4, and 5

136 s in both binding group can be found in both genogroups I and II.

137 the human norovirus strains classified into genogroups I and II.

138 0), with the majority of positives caused by genogroup II (82%, n = 74).

139 NoVs that belong to genogroup II (GII) are quite prevalent and prone to unde

140 Incidence of genogroup II (GII) infection was higher than genogroup I

141 Genogroup II (GII) infections were 3 times more frequent

142 ) to analyze the interaction of citrate with genogroup II (GII) noroviruses.

143 Porcine genogroup II (GII) NoVs replicate in pigs, but their pat

144 argeting the 5' end of the capsid region for genogroup II (GII) NoVs, a group which includes human No

145 Genogroup II (GII) strains were the predominant type (73

146 groups I and II of the NLVs were detected; a genogroup II (GII) virus closely related to the Camberwe

147 We quantified adenovirus, norovirus genogroup II (GII), and F+ coliphage in the influent was

148 Norovirus-specific IgG antibodies to genogroup II (GII)-4-2010 New Orleans (NO), GII-4-1999,

149 identified as being caused by a recombinant genogroup II (rGII-3a) strain, fecal specimens collected

150 ts from both genogroup I (Norwalk virus) and genogroup II (VA387) noroviruses with trypsin resulted i

151 A limited number of other genogroup II and I strains were cocirculating.

152 Genogroup II comprised five pigmented strains: three wer

153 Genogroup II ehrlichia, including the agent of human gra

154 e strain structure of Anaplasma marginale, a genogroup II ehrlichial pathogen, in both an acute outbr

155 rium adolescentis (BifAd); one viral marker: genogroup II F-specific RNA bacteriophages (FRNAPH II);

156 s to rNV, thus establishing the diagnosis as genogroup II NLV infection.

157 A developed is specific for the diagnosis of genogroup II NLV infections.

158 outbreaks of gastroenteritis were tested for genogroup II NLV Mexico virus-specific immunoglobulin M

159 In sera from those infected with genogroup II NLVs in volunteer and outbreak studies, 28

160 and 2.2 times as likely to be infected with genogroup II non-4 noroviruses (95% CI, 1.2-4.2) compare

161 Overall, genogroup II norovirus (NoV) strains were the most abund

162 All outbreaks were caused by a genogroup II norovirus related to the Lordsdale virus (G

163 virus (a genogroup I norovirus) or MD145 (a genogroup II norovirus) was fused to the C terminus of e

164 nt-based vaccine against Narita 104 virus, a Genogroup II Norovirus.

165 ecognizes A- and H-type HBGA, in contrast to genogroup II noroviruses that exhibit a more diverse HBG

166 Two genogroup II noroviruses, one representing the Toronto g

167 tained from adult volunteers inoculated with genogroup II Norwalk-like viruses (NLVs), Hawaii virus,

168 Genogroup II NVs were responsible for 83% of the outbrea

169 sby or Girlington (P < 0.0001) than by other genogroup II or I strains.

170 (38.4%) to segment 2 of the prototype human genogroup II strain 4-GA-91.

171 rsing homes were more likely to be caused by genogroup II strain Grimsby or Girlington (P < 0.0001) t

172 Noroviruses (NoVs) of genogroup II, cluster 4 (GII.4), are the most common cau

173 e genetic lineages were distinguished within genogroup II, composed of strains serologically characte

174 Rotavirus, norovirus genogroup II, Cryptosporidium, and Shigella species/ente

175 Human noroviruses (NoVs) of genogroup II, genotype 4 (GII.4) are the most common str

176 are genetically related, segregating in the genogroup II, genotype 4 (GII.4) cluster within the Noro

177 All genogroup II, genotype 4 (GII.4) infections were among s

178 t strains; and furthers our understanding of genogroup II, genotype 4 (GII.4) norovirus immune-driven

179 Genogroup II, genotype 4 (GII.4) noroviruses are known t

180 Genogroup II, genotype 4 NoVs (GII.4) remain the dominan

181 derived from NV (genogroup I, GI) and MD145 (genogroup II, GII) noroviruses as vaccines.

182 p I-cross-reactive monoclonal antibody and a genogroup II-cross-reactive monoclonal antibody by use o

183 ajority of norovirus outbreaks are caused by genogroup II.4 (GII.4).

184 CI], 3.9-24.8) as likely to be infected with genogroup II.4 noroviruses and 2.2 times as likely to be

185 A human norovirus genogroup II.4 strain HS66 (HuNoV-HS66) infects and caus

186 cimens, as well as that of genogroup I.1 and genogroup II.4 virus-like particles, were compared in a

187 gions had an annual peak in 2002 and the new genogroup II4 variant was detected in nine countries.

188 ce of a new predominant norovirus variant of genogroup II4, which had a consistent mutation in the po

189 capsid genes of Bo/CV186-OH/00/US (Norovirus genogroup III [GIII], genotype 2 [GIII/2]).

190 ese analyses, 15 BECVs belonged to Norovirus genogroup III and genotype 2 (GIII/2) and were genetical

191 Although genogroup I strain fr and genogroup III strains MX1 and M11 share only 70 to 78% s

192 The single strain (isolated in 1996) in genogroup III was pigmented and was the only strain asso

193 p antigen carbohydrates, bovine noroviruses (genogroup III) interact with alpha-galactosidase (alpha-

194 MX1 and M11 strains belong in Allolevivirus genogroup III.

195 groups (genogroups I and II in Levivirus and genogroups III and IV in Allolevivirus).

196 similarities among strains of Allolevivirus genogroups III and IV ranged from 70 to 96% and 75 to 95

197 lence of NoV diarrhea and in the predominant genogroup infecting travelers was demonstrated, dependen

198 rticles, this work shows that representative genogroup IV and VI viruses can interact with histo-bloo

199 ecific strains of norovirus are grouped into genogroups IV and VI, and this study is the first to cha

200 thogen in dogs, with strains classified into genogroups IV and VI.

201 re screened for NoV and characterized at the genogroup level (GI and GII).

202 hrlichiosis and aid in the classification of genogroup members.

203 Within this single genogroup, MNV strains exhibited considerable biological

204 The P[19] genotype belongs to the P[II] genogroup of group A rotaviruses (RVs).

205 mplete capsid, we identified a potential new genogroup of porcine SaVs, with Po/SaV/OH-JJ681/00/US as

206 inovirus and were found to belong to a novel genogroup of rhinovirus, genogroup C.

207 ifficulties in the serogrouping and capsular genogrouping of meningococcal carriage isolates.

208 sistent site and disease associations for 21 genogroups of Actinomyces spp. that provide greater insi

209 nalysis of selected strains in the two major genogroups of human NoVs (GI and GII) demonstrated highl

210 Recently, at least three new genogroups of porcine SaVs have been proposed.

211 VP8* sequences, RVs are grouped into five P genogroups (P[I] to P[V]), of which P[I], P[IV], and P[V

212 ce identity with strains in their respective genogroups, phylogenetic analyses of the complete genome

213 Strains within genogroups reacted more strongly than did strains betwee

214 e part of the hospital-associated E. faecium genogroup referred to as clonal complex 17 (CC17), which

215 The Enterococcus faecium genogroup, referred to as clonal complex 17 (CC17), seem

216 Isolate polymerase chain reaction genogrouping revealed 4 patterns: IVb (21 of 42, 50%), I

217 for the presence of Ehrlichia phagocytophila genogroup rickettsiae by using a nested PCR technique.

218 est that the prevalence of E. phagocytophila genogroup rickettsiae in ixodid ticks of California may

219 norovirus was present, after accounting for genogroup, rotavirus vaccine, and age.

220 version against GI VLPs, indicating a highly genogroup-specific antibody response.

221 viral load, fever duration, and serological genogroup-specific neutralization titer.

222 ars in specific Asian countries representing genogroup-specific sources of EV-A71 diversity.

223 e epitope explains the monoclonal antibody's genogroup specificity.

224 Furthermore, within genogroups, sporadic recombination events occurred, such

225 ) based on their similarities to proteins of genogroup strains (Wa, DS-1, or AU-1, respectively).

226 acteristics of Haemophilus influenzae type b genogroup strains isolated from genitourinary tract spec

227 cordingly, our analysis reveals that a rapid genogroup switch from C4 to B5 likely took place during

228 nd recognition of noroviruses from different genogroups, the prototypic Norwalk virus (NV; GI-1) and

229 and the commonly used murine norovirus (MNV, genogroup V) model.

230 ha-Gal) carbohydrates, and murine norovirus (genogroup V) recognizes sialic acids.

231 disease-associated polysaccharide capsules; genogroup W predominated, and genogroup A was rare.

232 ar genogroups detected by broth culture were genogroups W (21 isolates), B (12 isolates), Y (8 isolat

233 an VP4 and VP7 between major human rotavirus genogroups was observed.

234 Repeat infections by the same genogroup were common, but repeat infections by the same

235 ks, and strains belonging to a tentative new genogroup were identified.

236 Viral load and genogroups were influenced by immunosuppression.

237 within the same (n = 3) or different (n = 5) genogroups were observed in eight children.

238 One biotype was common to several genogroups, with all of these isolates being identified

239 Noroviruses are divided into 6 genogroups, with human strains grouped into genogroups I

240 BEC strains detected in Europe form a third genogroup within the genus "Norwalk-like viruses" (NLV)