ライフサイエンスコーパス: genome sequence

1 ilarity >90% (>84% for HDV-1) over the whole genome sequence.

2 roduce and annotate a high-quality reference genome sequence.

3 fier (RGI) for resistome prediction from raw genome sequence.

4 typing (MSG), and located MSG markers to the genome sequence.

5 predicted transcript to the T. coronopifolia genome sequence.

6 haplotypes using reads mapped to a reference genome sequence.

7 e genome, and covered 98.6% of the reference genome sequence.

8 f this genus (Ca. N. devanaterra) having its genome sequenced.

9 ne susceptibility were determined from whole genome sequences.

10 explained by current knowledge obtained from genome sequences.

11 nd intestinal biomes have no closely related genome sequences.

12 tics including methicillin and had identical genome sequences.

13 poor results when genes are predicted in new genome sequences.

14 liable computational prediction of piRNAs in genome sequences.

15 nd automatically annotate ISs in prokaryotic genome sequences.

16 RC, we identified rare variants for complete genome sequencing.

17 olymerase chain reaction (rt-PCR), and whole genome sequencing.

18 rtunities and challenges introduced by whole-genome sequencing.

19 population over the past decade using whole-genome sequencing.

20 tool for detecting CNAs from whole exome and genome sequencing.

21 ion analysis, slide agglutination, and whole-genome sequencing.

22 e characterized this interaction using whole-genome sequencing.

23 ete antibiotics resistance in bacteria using genome sequencing.

24 pened new possibilities for 'benchtop' whole-genome sequencing.

25 -2013, using both long- and short-read whole-genome sequencing.

26 drugs, confirmatory Wayne's assay, and whole-genome sequencing.

27 ds, followed by delayed subcloning and whole-genome sequencing.

28 By combining very deep whole genome sequencing ( 1000-fold genome-wide coverage) with

29 We whole genome sequenced 223 randomly selected M. tuberculosis s

30 nalysis from targeted, whole-exome, or whole-genome sequencing a wellspring to identify new SNPs asso

31 Genome sequence analysis of these samples revealed a sig

32 Genome sequence analysis was performed on multiple cultu

33 Whole-genome sequence analysis was used to assess the phylogen

34 Whole-genome sequencing analysis of lung adenocarcinomas revea

35 f H. parasuis that had previously been whole-genome sequenced and a further 84 isolates from the Unit

36 n (NCBI) database contained >2 million viral genome sequences and a reference set of 4000 viral geno

37 The ability to obtain accurate genome sequences and haplotype information from single c

38 Whole-genome sequencing and a genome-wide association study pe

39 Advances in genome sequencing and assembly are being used to access

40 the blaOXA-232 gene were subjected to whole-genome sequencing and chromosome single-nucleotide polym

41 he pressure of PIs using Gag-protease single genome sequencing and coevolution analysis of protein se

42 ostic samples were characterized using whole genome sequencing and combined with epidemiological data

43 Genome sequencing and comparative genomic analyses of 94

44 We also did whole genome sequencing and core genome multilocus sequence ty

45 Recent exponential advances in genome sequencing and engineering technologies have enab

46 We subjected these strains to whole-genome sequencing and evolutionary convergence analysis,

47 d 95 primary PDAC cases that underwent whole-genome sequencing and expression microarray on bulk bios

48 In this study, we used whole-genome sequencing and gene expression profiling of 215 h

49 munology, as well as new approaches of whole-genome sequencing and genes newly reported to be associa

50 In this study, whole-genome sequencing and high-resolution (13)C-metabolic fl

51 Whole-genome sequencing and induced pluripotent stem cells wer

52 Genome sequencing and phylogenetic analysis of 387 isola

53 We used whole-genome sequencing and phylogenetic analysis to investiga

54 nation of resistant mutant generation, whole genome sequencing and recombineering to identify the tar

55 Identity was confirmed by full-genome sequencing and was not attributable to limited vi

56 pression as a quantitative trait using whole genome-sequencing and transcriptome analysis allows to d

57 ssion profile, RNA sequence, whole-exome and genome sequence, and immunohistochemical analyses of sel

58 ertions comprise as much as 17% of the human genome sequence, and similar proportions have been recor

59 entification assays derived from chloroplast genome sequences are discussed in light of product safet

60 in few instances correction of the reference genome sequence assembly.

61 oughput nanopore sequencers, mean that human genome sequencing at scale is now possible.

62 Using a whole genome sequencing-based approach, we developed two high-

63 argets and DTIs, such as chemical structure, genome sequence, binding types, causes of interactions,

64 same genus and which has a nearly identical genome sequence but not isolated from a uranium-rich bio

65 ble to obtain high-quality de novo assembled genome sequences but in practice DNA extracts are often

66 We determined whole-genome sequences by Illumina paired-reads sequencing, co

67 Whole-genome sequences can be used to improve viral classifica

68 Whole-genome sequencing can measure of the heterogeneity of dr

69 ype of ionizing radiation (IR) resistance, a genome sequence cannot predict whether a cell is IR-resi

70 ted during a 9-month period, including whole genome sequences; clinical tests, metabolomes, proteomes

71 Whole genome sequencing confirmed the ocular vOka strain to be

72 Samples of multiple complete genome sequences contain vast amounts of information abo

73 omogenates, we assembled a contiguous 174-kb genome sequence containing 128 unique predicted open rea

74 ntury, and advances in chemical analysis and genome sequencing continue to greatly advance our unders

75 d that two were complete denitrifiers, which genome sequencing corroborated.

76 candidate cancer genes and whole-exome and -genome sequencing, coupled with encouraging clinical res

77 The recent surge in genome sequence data and functional genomics research ha

78 he addition of novel alleles discovered from genome sequence data are likely to be particularly signi

79 Here, we queried whole-genome sequence data from 1,916 patients across 24 cance

80 We analyzed whole-genome sequence data from families affected by Alzheimer

81 By analyzing genome sequence data from human populations, including 1

82 5 AF cases and 374,939 controls, using whole-genome sequence data from the Icelandic population, and

83 We generated deep, whole-genome sequence data of 17 individuals in a three-genera

84 orces operating on bacterial IGRs from whole-genome sequence data, and suggests that our current unde

85 ps among closely-related bacteria from whole-genome sequence data.

86 Here using a large whole-genome sequencing data bank, cancer registry and colorec

87 By taking advantage of genome sequencing data from the 1001 Genomes Consortium,

88 However, whole-genome sequencing data revealed at least five independen

89 eral RNA-Seq data sets, as well as the whole genome sequencing data that was used in the construction

90 Whole genome sequencing data were analyzed for rare pLoF varia

91 or content in cfDNA from 0.1x coverage whole-genome sequencing data without prior knowledge of tumor

92 asingly available genotyping tools and whole-genome sequencing data, and argue for a better integrati

93 ally fast, enabling the application to whole-genome sequencing data, and straightforward to implement

94 g high-coverage exome and low-coverage whole-genome sequencing data, utilizing information from both

95 ne structural variation breakpoints in whole-genome sequencing data.

96 identify and mitigate batch effects in whole genome sequencing data.

97 line to recover immune receptor alleles from genome sequencing data.

98 ting downstream analysis functions for whole genome sequencing data.

99 so consider how emerging data types, such as genome-sequence data, can serve as proxies for microbial

100 n GC-rich regions that have poor coverage in genome sequence databases.

101 en other statistics are applied to the whole genome sequencing dataset from the TwinsUK study.

102 causative variants in whole exome and whole genome sequencing datasets and provides a powerful resou

103 Comprehensive genome sequencing did not reveal any pathogenic coding o

104 vestigating Mendelian disease using exome or genome sequencing, distinguishing disease-causing geneti

105 sy specimens in this region, revealing whole-genome sequence diversity.

106 Recently, cancer genome sequencing efforts have identified recurrent Rheb

107 Our data provide a framework for how future genome sequencing efforts should incorporate transcripto

108 /lymphoma and gastric cancer by human cancer genome sequencing efforts, suggesting both pro- and anti

109 and can support the forthcoming white lupin genome sequencing efforts.

110 With the avalanche of genome sequences emerging in the post-genomic age, it is

111 g assay based on target enrichment and whole-genome sequencing (eWGS).

112 ome mapping, to generate a reference-quality genome sequence for Ae. tauschii ssp. strangulata access

113 f a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using sin

114 educed costs of sequencing have led to whole-genome sequences for a large number of microorganisms, e

115 rom single cells will enable applications of genome sequencing for diverse clinical needs.

116 Population genomic analyses of whole-genome sequences from 32 individuals showed that genes w

117 ng data (1998-2014) were combined with whole genome sequences from 4045 national and international C

118 Here we examined a data set of whole-genome sequences from 5,310 M. tuberculosis isolates fro

119 By analysing 92 newly generated viral genome sequences from blood donors and recipients, we as

120 urce hosts a database of human mitochondrial genome sequences from individuals with healthy and disea

121 ft in the host preference, we analyzed whole genome sequences from laboratory and natural populations

122 a notion supported by more than 60 complete genome sequences from multiple isolates and following mu

123 t in the Upper Paleolithic, we used complete genome sequences from Sunghir, a site dated to 34,000 y

124 Here, we report 18 novel EBV genome sequences from viruses isolated from primary NPC

125 mean physical coverage and linked-read whole-genome sequencing from 10X Genomics, we document seven m

126 i isolates previously characterized by whole-genome sequencing from the CDC-FDA Antibiotic Resistance

127 Here we establish, through fine mapping, genome sequencing, genetic complementation, and gene edi

128 Whole-genome sequencing gives unprecedented power to detect th

129 infection (MOIs) for 11 generations and the genome sequences, growth kinetics, and protein expressio

130 The bottle gourd genome sequence has facilitated the mapping of a dominan

131 draft genomes, however, the 158-Mb Spirodela genome sequence has not been resolved to chromosomes, an

132 More recently, M. tuberculosis whole-genome sequencing has been used to estimate population l

133 ation of resistant mutants followed by whole genome sequencing has often been successful in uncoverin

134 Single-cell genome sequencing has proven valuable for the detection

135 However, genome sequencing has revealed that many mammal and bird

136 Genome sequencing has revolutionized the diagnosis of ge

137 The development of rapid, economical genome sequencing has shed new light on the classificati

138 s for copy-number variation calling in whole genome sequencing have been published, the noisy nature

139 Whole-exome and whole-genome sequencing have facilitated the large-scale disco

140 y remains completely unexplored, advances in genome sequencing have provided unprecedented glimpses i

141 Whole genome sequencing identified a highly expressed FGF4 ret

142 Whole exome or genome sequencing identified segregating homozygous vari

143 Whole-genome sequencing identified specific genes associated w

144 apability for determining the actual diploid genome sequence in a sample, opening the door to new app

145 lly based on the availability of more fungal genome sequences in recent years.

146 revealed distinct but closely related STLV-1 genome sequences in two baboons, extremely low heterogen

147 Whole genome sequencing in 98 Hutterites, a founder population

148 Although genome sequencing in principle reveals all genetic varia

149 ting the necessity of complete mitochondrial genome sequencing in the diagnostic work-up of patients

150 nce and power of strain validation and whole genome sequencing in this context.

151 to facilitate the analysis of related whole genome sequences, in both a population and comparative g

152 tant step of information processing from the genome sequences into cellular mechanisms.

153 Debugging a genome sequence is imperative for successfully building

154 However, the whole-genome sequence is sometimes needed for higher resolutio

155 Whole-genome sequencing is an increasingly important comprehen

156 ny stable flea cell line or a published flea genome sequence, little is known regarding R. typhi biol

157 Rapid advances in genome sequencing make it possible to identify multiple

158 Protocol for individual templates-Bisulfite Genome Sequencing (MAPit-BGS) and nucleosome occupancy a

159 SE-regulated genes identified by whole-exome/genome sequencing may have greater significance than pre

160 s, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Meta

161 Whole genome sequencing mixes the signals of sampled populatio

162 , recent advances in genetic tool design and genome sequencing now confer huge advantages in the fly

163 Additionally, a finished mitochondrial genome sequence of 135,790 bp was obtained, which contai

164 his study, we report a high-quality 313.4-Mb genome sequence of a bottle gourd inbred line, USVL1VR-L

165 7.IMPORTANCE Herein we describe the complete genome sequence of a novel murine herpesvirus.

166 Here, we report the low-coverage genome sequence of an ancient individual known as "Shuka

167 Here, a draft genome sequence of B. cookei was obtained and analyzed.

168 aceae genome evolution, and the high-quality genome sequence of bottle gourd provides a useful resour

169 3 loci identified in the reannotation of the genome sequence of C. jejuni isolate NCTC 11168, chosen

170 s this goal, we have determined the complete genome sequence of LdCen (-/-) and its parent strain Ld1

171 The controllable life cycle and the genome sequence of P. multistriata allow the reconstruct

172 The genome sequence of pomegranate provides a valuable resou

173 Here we report the draft genome sequence of spinach (Spinacia oleracea, 2n=12), w

174 terize the breakdown of SI, we built a draft genome sequence of T. coronopifolia, genotyped F2 plants

175 ctive L1 retrotransposons from the reference genome sequences of 17 mammals.

176 We have analyzed the publicly available genome sequences of 36 popular inbred strains and provid

177 We used whole genome sequences of 469 B. pseudomallei isolates from 30

178 Here, we report high-quality genome sequences of C. maxima and C. moschata and provid

179 The genome sequences of eight aspergilli have already been e

180 or nonsense mutants associated with culture, genome sequences of eleven long-term laboratory-adapted

181 ins in these subclades are asyntenous to the genome sequences of members of their neighbour subgroups

182 Whole-genome sequences of representative highly pathogenic avi

183 Furthermore, analyses of allelic genome sequences of several populations within these lin

184 netic distance from described subgroups, the genome sequences of strains in these subclades are asynt

185 we generated germline and somatic reference genome sequences of the DNA eliminating pig parasitic ne

186 We performed whole-genome sequencing of 102 primary PanNETs and defined the

187 apple genome variation map generated through genome sequencing of 117 diverse accessions.

188 n and loss of methicillin resistance through genome sequencing of 180 isolates from 2016.

189 ulti-allelic clusters, identified from whole-genome sequencing of 228 DO mice.

190 Phylogenetic analysis based on whole-genome sequencing of 250 isolates revealed two major M c

191 address this issue, we carried out 60x whole-genome sequencing of 26 metastases from four patients wi

192 ons in an additional 182 families, and whole-genome sequencing of 4 of the remaining 242 families rev

193 Whole exome and genome sequencing of a 19-year-old girl (P7), initially

194 ity has been characterized across cancers by genome sequencing of bulk tumors, including chronic lymp

195 Whole genome sequencing of CFW-passaged strains showed no spec

196 trolled laboratory conditions; and (4) whole-genome sequencing of clinical and environmental isolates

197 Here, we show whole-genome sequencing of DNA and RNA in 94 Chinese individua

198 We are performing whole-genome sequencing of families with autism spectrum disor

199 cumulated NO and N2 O to varying degrees and genome sequencing of four indicated that two isolates he

200 h in vitro microbiology approaches and whole-genome sequencing of Methanomicrobium mobile, a key spec

201 We further performed whole-genome sequencing of nosocomial MDRPa strains to evaluat

202 Whole-genome sequencing of pathogens from host samples becomes

203 In conclusion, whole-genome sequencing of samples obtained following neoadjuv

204 Genome sequencing of the immigrant identified it as a G.

205 , vaccine strains, and field isolates, whole-genome sequencing of the M. gallisepticum vaccine strain

206 Whole-genome sequencing of three mangrove species further show

207 sma hominis isolates were subjected to whole-genome sequencing on the Illumina NextSeq platform.

208 ividual-level phenotypes and realistic whole-genome sequence or SNP data.

209 lates previously characterized through whole-genome sequencing or targeted PCR as to the presence or

210 Recently, a whole-genome sequencing project was launched on the wild speci

211 ntribute to disease susceptibility as recent genome sequencing projects revealed a large number of in

212 t yet fully identified by large-scale cancer genome sequencing projects.

213 sed an explosion of successful ancient human genome-sequencing projects, with genomic-scale ancient D

214 by screening on admission studies and whole-genome sequencing, providing evidence for an endogenous

215 Although the current white spruce genome sequence remains highly fragmented, dozens of sca

216 Surprisingly, whole genome sequencing revealed that the coastal region harbo

217 tbreak strains from flour samples, and whole-genome sequencing revealed that the isolates from clinic

218 Whole genome sequencing revealed that the strain carried a pla

219 elected experiments from the paper "Melanoma genome sequencing reveals frequent PREX2 mutations".

220 mutants were subjected to MIC testing, whole-genome sequencing, reverse transcription-quantitative PC

221 Whole-genome sequencing revised 93% of karyotypes and demonstr

222 ata types, including exome sequencing, whole-genome sequencing, RNA-seq, ChIP-seq, targeted sequencin

223 cs tool for analysing large cohorts of whole-genome sequenced samples.

224 Whole-genome sequencing showed close relationships between env

225 A whole-genome sequence signature analysis identified 3 amino ac

226 ated in detail the relationship of the newly genome sequenced species with other aspergilli.

227 applying a combined linkage-based and whole-genome sequencing strategy and identified an in-frame ge

228 We performed whole-genome sequencing, structural modelling and cytogenetic

229 from publicly available whole-exome or whole-genome sequencing studies (4167 probands plus 1786 contr

230 Whole-exome and -genome sequencing studies employed here in large cohorts

231 of unknown significance identified in whole-genome sequencing studies.

232 We used a novel HPV whole-genome sequencing technique to evaluate an exceptionally

233 It is well-known that genome sequencing technologies are becoming significantl

234 sequences and a reference set of 4000 viral genome sequences that cover a wide range of known viral

235 Given genome sequences, the AAScatterPlot tool compacts into a

236 So, with the increasing popularity of whole genome sequencing, the need has emerged for a faster app

237 This is exemplified by employing the genome sequence to clone and functionally characterize t

238 ap anchored 1,602 scaffolds of the reference genome sequence to LGs, accounting for over 97% of the t

239 Specifically, we utilize 7,444 whole-genome sequences to examine the effect of variants on th

240 Here we use whole-genome sequences to examine the origin and adaptation of

241 ed molecular genetics, proteomics, and whole-genome sequencing to demonstrate that the MMAR_0039 gene

242 d for prescreening of patients through whole-genome sequencing to ensure safety.

243 The application of single-cell genome sequencing to large cell populations has been hin

244 We used single-cell whole-genome sequencing to perform genome-wide somatic single-

245 Here, we used whole-genome sequencing to scan high-altitude Andeans for sign

246 lates were analysed by next-generation whole-genome sequencing using Illumina and Pacific Biosciences

247 Progress in whole-genome sequencing using short-read (e.g., <150 bp), next

248 p1 of our laboratory isolate of the straight genome sequenced variant of 11168 (11168-GS) was also id

249 r present inability to predict the effect of genome sequence variation on DNA methylation precludes a

250 In addition, the full-length genome sequence was generated for 116 strains selected f

251 Each of the HSV-2 genome sequences was initially obtained using next-gener

252 Whole-genome sequencing was applied to investigate the genetic

253 Shallow whole-genome sequencing was performed on an Illumina platform,

254 Whole-genome sequencing was performed on human and fish ST283

255 Whole-genome sequencing was performed on isolates from clinica

256 Here, whole-genome sequencing was used to demonstrate nosocomial acq

257 Whole-exome sequencing or whole-genome sequencing was used to identify the causative var

258 With the advent of whole genome sequencing we are in the midst of a paradigm shif

259 Using available genome sequences, we observed that a significant number

260 Spoligotyping and whole-genome sequencing were performed to ascertain homogeneit

261 However, compared to whole genome sequencing, WES introduces more biases and noise

262 scovery population of individuals with whole-genome sequence (WGS) data from the UK10K project (n = 1

263 Recently, whole-genome sequences (WGS) of many human and animal pathogen

264 Whole-genome sequencing (WGS) allows for a comprehensive view

265 with these outbreaks were analyzed by whole-genome sequencing (WGS) analysis.

266 Whole exome sequencing and whole genome sequencing (WGS) are entering clinical use, posin

267 Whole-genome sequencing (WGS) can generate antibiotic suscepti

268 Whole-genome sequencing (WGS) can help by providing complete k

269 Whole-genome sequencing (WGS) can provide excellent resolution

270 Whole genome sequencing (WGS) confirmed that the A. gambiae Y

271 Whole-genome sequencing (WGS) could offer significant advantag

272 Whole-genome sequencing (WGS) data enable the improvement of s

273 yndrome, is challenging for short-read whole-genome sequencing (WGS) data.

274 The application of whole-genome sequencing (WGS) has become routine for trace bac

275 Whole-genome sequencing (WGS) has the potential to accelerate

276 d Estonian Biobank using high-coverage whole-genome sequencing (WGS) in 2,284 samples and SNP genotyp

277 Whole-genome sequencing (WGS) in asymptomatic adults might pre

278 Whole-genome sequencing (WGS) is a newer alternative for tuber

279 Whole-genome sequencing (WGS) is an emerging and powerful tech

280 n sequence variants identified through whole-genome sequencing (WGS) of 15,220 Icelanders for associa

281 pproximately 9.5 million variants from whole-genome sequencing (WGS) of a Cretan-isolated population,

282 ormed whole-exome sequencing (WES) and whole-genome sequencing (WGS) on AVM tissue from affected indi

283 (LHL and LGL) were subjected to three whole genome sequencing (WGS) runs with different devices (MiS

284 We further performed a whole genome sequencing (WGS) scan for Alzherimer's disease ne

285 poson capture sequencing (mRC-seq) and whole-genome sequencing (WGS) to pedigrees of C57BL/6J animals

286 The organism-specific bioinformatics whole-genome sequencing (WGS) typing pipelines at Public Healt

287 Whole genome sequencing (WGS) was performed to produce a phylo

288 ogy laboratories underwent culture and whole-genome sequencing (WGS), using WGS to identify toxigenic

289 g pulsed-field gel electrophoresis and whole-genome sequencing (WGS).

290 n, and outbreak investigation by using whole-genome sequencing (WGS).

291 f patients from the Western Cape using whole-genome sequencing (WGS; n=149), a cough aerosol sampling

292 e potential threat is evident from the human genome sequence, which reveals many past epidemics of ga

293 , and a new-generation approach to the whole-genome sequencing, which will lead to the reference-grad

294 vanced technologies, including ordered-clone genome sequencing, whole-genome shotgun sequencing, and

295 e reported transgenesis method and annotated genome sequence will permit sophisticated genetic studie

296 Complementing genome sequence with deep transcriptome and proteome dat

297 quality scores for all available prokaryotic genome sequences with a user-friendly Web-interface.

298 We provide a first exploration of patient genome sequencing with a nanopore sequencer and demonstr

299 Large sample sets of whole genome sequencing with deep coverage are being generated

300 q, targeted sequencing and single-cell whole-genome sequencing, with a minimal requirement for sequen