ライフサイエンスコーパス: genome sequencing

1 olymerase chain reaction (rt-PCR), and whole genome sequencing.

2 rtunities and challenges introduced by whole-genome sequencing.

3 population over the past decade using whole-genome sequencing.

4 tool for detecting CNAs from whole exome and genome sequencing.

5 ion analysis, slide agglutination, and whole-genome sequencing.

6 ion, ribosomal protein characterization, and genome sequencing.

7 osely-related bacteria on the basis of whole-genome sequencing.

8 ic and we have identified the mutant gene by genome sequencing.

9 Serotype was determined by whole-genome sequencing.

10 rrent MDD was partitioned using sparse whole-genome sequencing.

11 species and type were determined by partial genome sequencing.

12 e characterized this interaction using whole-genome sequencing.

13 dentified by using metagenomics and complete genome sequencing.

14 ete antibiotics resistance in bacteria using genome sequencing.

15 using high-density SNP genotyping and whole-genome sequencing.

16 dividual Drosophila melanogaster using whole-genome sequencing.

17 pened new possibilities for 'benchtop' whole-genome sequencing.

18 -2013, using both long- and short-read whole-genome sequencing.

19 drugs, confirmatory Wayne's assay, and whole-genome sequencing.

20 ds, followed by delayed subcloning and whole-genome sequencing.

21 RC, we identified rare variants for complete genome sequencing.

22 DNA using Tagged-Amplicon- and shallow Whole Genome- Sequencing.

23 By combining very deep whole genome sequencing ( 1000-fold genome-wide coverage) with

24 Whole genome sequencing a collection of the first MRSA isolate

25 nalysis from targeted, whole-exome, or whole-genome sequencing a wellspring to identify new SNPs asso

26 Progress in genome sequencing achieved during the last two decades r

27 Comparative whole-genome sequencing analysis of emm32.2 iGAS and non-emm32

28 Whole-genome sequencing analysis of lung adenocarcinomas revea

29 e ORF 12 deletion, revealed through targeted genome sequencing analysis, points to the need to authen

30 ral RNAi in Arabidopsis thaliana Using whole-genome sequencing and a computational pipeline, we ident

31 Whole-genome sequencing and a genome-wide association study pe

32 Evolved strains can be analyzed by whole genome sequencing and an array of omics technologies.

33 Advances in genome sequencing and assembly are being used to access

34 assicaceae and pave the way for future whole-genome sequencing and assembly efforts in this as yet ge

35 Although fungal genome sequencing and assembly have become trivial, its

36 Advances in genome sequencing and assembly technologies are generati

37 Despite the recent progress in genome sequencing and assembly, many of the currently av

38 High-throughput genome sequencing and bioinformatics are enhancing our a

39 the blaOXA-232 gene were subjected to whole-genome sequencing and chromosome single-nucleotide polym

40 he pressure of PIs using Gag-protease single genome sequencing and coevolution analysis of protein se

41 ostic samples were characterized using whole genome sequencing and combined with epidemiological data

42 Genome sequencing and comparative genomic analyses of 94

43 We also did whole genome sequencing and core genome multilocus sequence ty

44 hnical aspects and challenges of single-cell genome sequencing and discuss some of the scientific end

45 iversity and characterize clones using whole-genome sequencing and doubling time measurements.

46 Recent exponential advances in genome sequencing and engineering technologies have enab

47 We subjected these strains to whole-genome sequencing and evolutionary convergence analysis,

48 d 95 primary PDAC cases that underwent whole-genome sequencing and expression microarray on bulk bios

49 In this study, we used whole-genome sequencing and gene expression profiling of 215 h

50 munology, as well as new approaches of whole-genome sequencing and genes newly reported to be associa

51 mic approach includes a combination of whole-genome sequencing and genome-wide microarray technologie

52 ofluidic reactors), for accurate single-cell genome sequencing and haplotyping.

53 In this study, whole-genome sequencing and high-resolution (13)C-metabolic fl

54 e for rs74315329 were identified using whole-genome sequencing and imputation data (based on 1000 Gen

55 Whole-genome sequencing and induced pluripotent stem cells wer

56 To achieve this, we conducted whole genome sequencing and lung function tests in 19 Argentin

57 Through full-genome sequencing and phylogenetic analyses, we could id

58 Genome sequencing and phylogenetic analysis of 387 isola

59 We used whole-genome sequencing and phylogenetic analysis to investiga

60 Whole genome sequencing and quantitative real-time polymerase

61 nation of resistant mutant generation, whole genome sequencing and recombineering to identify the tar

62 We tested this hypothesis using whole-genome sequencing and transcriptomic data, and we discov

63 Genome sequencing and variant analysis of the surviving

64 Identity was confirmed by full-genome sequencing and was not attributable to limited vi

65 pression as a quantitative trait using whole genome-sequencing and transcriptome analysis allows to d

66 ng molecular tests and next-generation whole-genome sequencing, and their potential for clinical effe

67 r 4 years, with 279 clones sampled for whole genome sequencing at different time points.

68 oughput nanopore sequencers, mean that human genome sequencing at scale is now possible.

69 way, with the single goal of enabling whole-genome sequencing at scale.

70 Using a whole genome sequencing-based approach, we developed two high-

71 ng from denser reference panels, until whole-genome sequencing becomes feasible in large samples.

72 Whole-genome sequencing can measure of the heterogeneity of dr

73 itive cell-associated HIV RNA and DNA single-genome sequencing (CARD-SGS) method to investigate fract

74 Whole genome sequencing confirmed the ocular vOka strain to be

75 ntury, and advances in chemical analysis and genome sequencing continue to greatly advance our unders

76 d that two were complete denitrifiers, which genome sequencing corroborated.

77 candidate cancer genes and whole-exome and -genome sequencing, coupled with encouraging clinical res

78 We present deep whole-genome sequencing data ( approximately 38x) from 28 indi

79 Here using a large whole-genome sequencing data bank, cancer registry and colorec

80 Using whole-genome sequencing data from 163 vervets sampled from acr

81 We used whole-genome sequencing data from 2,619 individuals through th

82 We have applied BeviMed to whole-genome sequencing data from 6,586 individuals with diver

83 By taking advantage of genome sequencing data from the 1001 Genomes Consortium,

84 This study compares whole-genome sequencing data obtained from chemo-naive and che

85 The analysis of human whole-genome sequencing data presents significant computationa

86 However, whole-genome sequencing data revealed at least five independen

87 eral RNA-Seq data sets, as well as the whole genome sequencing data that was used in the construction

88 Whole genome sequencing data were analyzed for rare pLoF varia

89 or content in cfDNA from 0.1x coverage whole-genome sequencing data without prior knowledge of tumor

90 asingly available genotyping tools and whole-genome sequencing data, and argue for a better integrati

91 ally fast, enabling the application to whole-genome sequencing data, and straightforward to implement

92 With the availability of massive whole genome sequencing data, it becomes practical to mine STR

93 g high-coverage exome and low-coverage whole-genome sequencing data, utilizing information from both

94 ting downstream analysis functions for whole genome sequencing data.

95 hundreds of thousands of samples with whole-genome sequencing data.

96 ociations impacted by batch effects in whole genome sequencing data.

97 edicting microbial resistance patterns using genome sequencing data.

98 ne structural variation breakpoints in whole-genome sequencing data.

99 identify and mitigate batch effects in whole genome sequencing data.

100 line to recover immune receptor alleles from genome sequencing data.

101 en other statistics are applied to the whole genome sequencing dataset from the TwinsUK study.

102 causative variants in whole exome and whole genome sequencing datasets and provides a powerful resou

103 P3, capable of mapping high-throughput whole genome sequencing datasets.

104 ited for large, possible low-coverage, whole genome sequencing datasets.

105 Comprehensive genome sequencing did not reveal any pathogenic coding o

106 dying emerging infectious diseases; however, genome sequencing directly from clinical samples (i.e.,

107 tions of targeted therapies emerge and tumor genome sequencing discovers increasingly comprehensive m

108 vestigating Mendelian disease using exome or genome sequencing, distinguishing disease-causing geneti

109 Recently, cancer genome sequencing efforts have identified recurrent Rheb

110 Our data provide a framework for how future genome sequencing efforts should incorporate transcripto

111 /lymphoma and gastric cancer by human cancer genome sequencing efforts, suggesting both pro- and anti

112 and can support the forthcoming white lupin genome sequencing efforts.

113 g assay based on target enrichment and whole-genome sequencing (eWGS).

114 mparative analysis of the various methods of genome sequencing focusing on verification of the assemb

115 rom single cells will enable applications of genome sequencing for diverse clinical needs.

116 mean physical coverage and linked-read whole-genome sequencing from 10X Genomics, we document seven m

117 i isolates previously characterized by whole-genome sequencing from the CDC-FDA Antibiotic Resistance

118 Technologies such as genome sequencing, gene expression profiling, proteomic

119 Here we establish, through fine mapping, genome sequencing, genetic complementation, and gene edi

120 Whole-genome sequencing gives unprecedented power to detect th

121 Genome sequencing has become a powerful tool for studyin

122 More recently, M. tuberculosis whole-genome sequencing has been used to estimate population l

123 A deluge of whole-genome sequencing has begun to give insights into the pa

124 Cancer genome sequencing has implicated the cytosine deaminase

125 ation of resistant mutants followed by whole genome sequencing has often been successful in uncoverin

126 Single-cell genome sequencing has proven valuable for the detection

127 Genome sequencing has reinvigorated this field, shedding

128 However, genome sequencing has revealed that many mammal and bird

129 in MYXV that are critical for virulence, and genome sequencing has revealed the evolutionary history

130 Genome sequencing has revolutionized the diagnosis of ge

131 The development of rapid, economical genome sequencing has shed new light on the classificati

132 Large-scale genome sequencing has the potential to provide new insig

133 s for copy-number variation calling in whole genome sequencing have been published, the noisy nature

134 Whole-exome and whole-genome sequencing have facilitated the large-scale disco

135 Advancements in genome sequencing have led to the rapid accumulation of

136 y remains completely unexplored, advances in genome sequencing have provided unprecedented glimpses i

137 Large-scale genome sequencing holds great promise for the interpreta

138 Whole genome sequencing identified a highly expressed FGF4 ret

139 Whole genome sequencing identified a likely pair of biosynthet

140 In addition, whole-genome sequencing identified mutations enriched in liver

141 Whole exome or genome sequencing identified segregating homozygous vari

142 Whole-genome sequencing identified specific genes associated w

143 Whole-exome sequencing and whole-genome sequencing identified the same homozygous SRD5A3

144 Whole genome sequencing in 98 Hutterites, a founder population

145 Here, we describe the utility of whole-genome sequencing in defining nosocomial VREfm transmiss

146 Although genome sequencing in principle reveals all genetic varia

147 ting the necessity of complete mitochondrial genome sequencing in the diagnostic work-up of patients

148 nce and power of strain validation and whole genome sequencing in this context.

149 uth African families and SNP array and whole-genome sequencing in two Norwegian families, we identifi

150 Whole-genome sequencing is an increasingly important comprehen

151 Based upon recent genome sequencing, it is clear that T2S is largely restr

152 Rapid advances in genome sequencing make it possible to identify multiple

153 Protocol for individual templates-Bisulfite Genome Sequencing (MAPit-BGS) and nucleosome occupancy a

154 SE-regulated genes identified by whole-exome/genome sequencing may have greater significance than pre

155 Whole genome sequencing mixes the signals of sampled populatio

156 nherited retinal disease, who have had whole-genome sequencing (n = 605), whole-exome sequencing (n =

157 , recent advances in genetic tool design and genome sequencing now confer huge advantages in the fly

158 We performed whole-genome sequencing of 102 primary PanNETs and defined the

159 apple genome variation map generated through genome sequencing of 117 diverse accessions.

160 n and loss of methicillin resistance through genome sequencing of 180 isolates from 2016.

161 ulti-allelic clusters, identified from whole-genome sequencing of 228 DO mice.

162 Phylogenetic analysis based on whole-genome sequencing of 250 isolates revealed two major M c

163 address this issue, we carried out 60x whole-genome sequencing of 26 metastases from four patients wi

164 ons in an additional 182 families, and whole-genome sequencing of 4 of the remaining 242 families rev

165 Whole exome and genome sequencing of a 19-year-old girl (P7), initially

166 Whole-genome sequencing of all patients allowed exclusion of p

167 ity has been characterized across cancers by genome sequencing of bulk tumors, including chronic lymp

168 Whole genome sequencing of CFW-passaged strains showed no spec

169 We used comparative whole-genome sequencing of chemically mutagenized and natural

170 trolled laboratory conditions; and (4) whole-genome sequencing of clinical and environmental isolates

171 Here, we show whole-genome sequencing of DNA and RNA in 94 Chinese individua

172 We are performing whole-genome sequencing of families with autism spectrum disor

173 cumulated NO and N2 O to varying degrees and genome sequencing of four indicated that two isolates he

174 h in vitro microbiology approaches and whole-genome sequencing of Methanomicrobium mobile, a key spec

175 We further performed whole-genome sequencing of nosocomial MDRPa strains to evaluat

176 Whole-genome sequencing of pathogens from host samples becomes

177 In conclusion, whole-genome sequencing of samples obtained following neoadjuv

178 with SNP calls closely concordant with whole-genome sequencing of selected lines.

179 inhibition of these compounds based on whole genome sequencing of spontaneous resistant mutants, whic

180 Genome sequencing of the immigrant identified it as a G.

181 , vaccine strains, and field isolates, whole-genome sequencing of the M. gallisepticum vaccine strain

182 Here we used whole-genome sequencing of the proposed serovar 16 reference s

183 Whole-genome sequencing of three mangrove species further show

184 Whole genome sequencing of UNG/SMUG1-deficient tumours reveale

185 Here, we performed whole genome sequencing on DNA from two affected individuals f

186 sma hominis isolates were subjected to whole-genome sequencing on the Illumina NextSeq platform.

187 lates previously characterized through whole-genome sequencing or targeted PCR as to the presence or

188 olecular analyses were performed using whole-genome sequencing or whole-exome sequencing.

189 Recently, a whole-genome sequencing project was launched on the wild speci

190 ntribute to disease susceptibility as recent genome sequencing projects revealed a large number of in

191 t yet fully identified by large-scale cancer genome sequencing projects.

192 sed an explosion of successful ancient human genome-sequencing projects, with genomic-scale ancient D

193 Haplotype-resolved genome sequencing promises to unlock a wealth of informa

194 by screening on admission studies and whole-genome sequencing, providing evidence for an endogenous

195 enetic alterations identified through cancer genome sequencing requires complementary approaches to i

196 We filtered whole-genome sequencing results to include only rare variants

197 Whole genome sequencing revealed little to no off-target mutat

198 Surprisingly, whole genome sequencing revealed that the coastal region harbo

199 tbreak strains from flour samples, and whole-genome sequencing revealed that the isolates from clinic

200 Whole genome sequencing revealed that the strain carried a pla

201 lication of enrichment protocols to targeted genome sequencing revealed the unexpected deletion of a

202 elected experiments from the paper "Melanoma genome sequencing reveals frequent PREX2 mutations".

203 mutants were subjected to MIC testing, whole-genome sequencing, reverse transcription-quantitative PC

204 Whole-genome sequencing revised 93% of karyotypes and demonstr

205 ata types, including exome sequencing, whole-genome sequencing, RNA-seq, ChIP-seq, targeted sequencin

206 Whole-genome sequencing showed close relationships between env

207 applying a combined linkage-based and whole-genome sequencing strategy and identified an in-frame ge

208 We performed whole-genome sequencing, structural modelling and cytogenetic

209 from publicly available whole-exome or whole-genome sequencing studies (4167 probands plus 1786 contr

210 Whole-exome and -genome sequencing studies employed here in large cohorts

211 and phylogenies for a given locus from large genome sequencing studies with relevant outgroups allow

212 of unknown significance identified in whole-genome sequencing studies.

213 We used a novel HPV whole-genome sequencing technique to evaluate an exceptionally

214 Next Generation Genome sequencing techniques became affordable for massi

215 Advances in genome sequencing technologies and genome-wide associati

216 It is well-known that genome sequencing technologies are becoming significantl

217 So, with the increasing popularity of whole genome sequencing, the need has emerged for a faster app

218 by the continuing decrease in costs of plant genome sequencing, they will allow genome mining technol

219 We used whole-genome sequencing to characterize cholera across the Ame

220 We coupled ecological sampling and genome sequencing to characterize the population genetic

221 ed molecular genetics, proteomics, and whole-genome sequencing to demonstrate that the MMAR_0039 gene

222 d several of the KDSR mutations, we employed genome sequencing to discover a pathogenic 346 kb invers

223 Here, we add complete nuclear genome sequencing to DNA barcoding, ecological distribut

224 d for prescreening of patients through whole-genome sequencing to ensure safety.

225 We used whole-genome sequencing to investigate intrafamilial spread am

226 The application of single-cell genome sequencing to large cell populations has been hin

227 We used single-cell whole-genome sequencing to perform genome-wide somatic single-

228 Here, we used whole-genome sequencing to scan high-altitude Andeans for sign

229 We used whole-genome sequencing to show that Tomelo does not carry any

230 Whole-genome sequencing uncovered a catastrophic genome rearra

231 lates were analysed by next-generation whole-genome sequencing using Illumina and Pacific Biosciences

232 Progress in whole-genome sequencing using short-read (e.g., <150 bp), next

233 Whole-genome sequencing was applied to investigate the genetic

234 Whole-genome sequencing was performed on all isolates, and gen

235 Shallow whole-genome sequencing was performed on an Illumina platform,

236 Whole-genome sequencing was performed on DNA from patients wit

237 Whole-genome sequencing was performed on human and fish ST283

238 Whole-genome sequencing was performed on isolates from clinica

239 Whole-genome sequencing was performed on study isolates to det

240 Whole-genome sequencing was performed, and using single nucleo

241 Here, whole-genome sequencing was used to demonstrate nosocomial acq

242 Whole-exome sequencing or whole-genome sequencing was used to identify the causative var

243 With the advent of whole genome sequencing we are in the midst of a paradigm shif

244 Using exome and genome sequencing, we identified the recurrent de novo m

245 Spoligotyping and whole-genome sequencing were performed to ascertain homogeneit

246 polymerase chain reaction (qPCR), and whole-genome sequencing were performed.

247 However, compared to whole genome sequencing, WES introduces more biases and noise

248 Whole-genome sequencing (WGS) allows for a comprehensive view

249 Deep whole genome sequencing (WGS) allows for the comprehensive stu

250 with these outbreaks were analyzed by whole-genome sequencing (WGS) analysis.

251 We applied a hybrid whole-genome sequencing (WGS) and deep imputation approach to

252 Whole exome sequencing and whole genome sequencing (WGS) are entering clinical use, posin

253 Whole-genome sequencing (WGS) can generate antibiotic suscepti

254 Whole-genome sequencing (WGS) can help by providing complete k

255 Whole-genome sequencing (WGS) can provide excellent resolution

256 Whole genome sequencing (WGS) confirmed that the A. gambiae Y

257 Whole-genome sequencing (WGS) could offer significant advantag

258 Whole-genome sequencing (WGS) data are being generated at an u

259 Whole-genome sequencing (WGS) data enable the improvement of s

260 Using simulations and whole-genome sequencing (WGS) data from multiple different dat

261 and phylodynamic analyses to bacterial whole genome sequencing (WGS) data have become essential in th

262 yndrome, is challenging for short-read whole-genome sequencing (WGS) data.

263 The application of whole-genome sequencing (WGS) has become routine for trace bac

264 Whole-genome sequencing (WGS) has the potential to accelerate

265 Whole-genome sequencing (WGS) identified a homozygous deep int

266 We performed whole-genome sequencing (WGS) in 197 individuals with unexplai

267 d Estonian Biobank using high-coverage whole-genome sequencing (WGS) in 2,284 samples and SNP genotyp

268 Whole-genome sequencing (WGS) in asymptomatic adults might pre

269 Whole-genome sequencing (WGS) is a newer alternative for tuber

270 Whole genome sequencing (WGS) is a promising strategy to unrav

271 Whole-genome sequencing (WGS) is an emerging and powerful tech

272 Whole-genome sequencing (WGS) makes it possible to determine t

273 n sequence variants identified through whole-genome sequencing (WGS) of 15,220 Icelanders for associa

274 pproximately 9.5 million variants from whole-genome sequencing (WGS) of a Cretan-isolated population,

275 Whole-genome sequencing (WGS) of clinical bacterial isolates h

276 We used whole-genome sequencing (WGS) of consecutive C. difficile isol

277 ormed whole-exome sequencing (WES) and whole-genome sequencing (WGS) on AVM tissue from affected indi

278 Microbial whole genome sequencing (WGS) provides a potential solution to

279 (LHL and LGL) were subjected to three whole genome sequencing (WGS) runs with different devices (MiS

280 We further performed a whole genome sequencing (WGS) scan for Alzherimer's disease ne

281 A viral whole-genome sequencing (WGS) strategy, based on PCR amplifica

282 This study used whole-genome sequencing (WGS) to determine strain relatedness

283 bloodstream infections (BSIs) and used whole-genome sequencing (WGS) to identify factors associated w

284 poson capture sequencing (mRC-seq) and whole-genome sequencing (WGS) to pedigrees of C57BL/6J animals

285 The organism-specific bioinformatics whole-genome sequencing (WGS) typing pipelines at Public Healt

286 To obtain a more complete view, whole genome sequencing (WGS) was analyzed in a large consangu

287 Whole genome sequencing (WGS) was performed to produce a phylo

288 ogy laboratories underwent culture and whole-genome sequencing (WGS), using WGS to identify toxigenic

289 g pulsed-field gel electrophoresis and whole-genome sequencing (WGS).

290 antifungal susceptibility testing and whole-genome sequencing (WGS).

291 on/deletion (indel) variants from deep whole-genome sequencing (WGS).

292 n, and outbreak investigation by using whole-genome sequencing (WGS).

293 f patients from the Western Cape using whole-genome sequencing (WGS; n=149), a cough aerosol sampling

294 , based on variants identified through whole-genome sequencing, which included 4,657 Icelandic patien

295 , and a new-generation approach to the whole-genome sequencing, which will lead to the reference-grad

296 vanced technologies, including ordered-clone genome sequencing, whole-genome shotgun sequencing, and

297 We provide a first exploration of patient genome sequencing with a nanopore sequencer and demonstr

298 Large sample sets of whole genome sequencing with deep coverage are being generated

299 q, targeted sequencing and single-cell whole-genome sequencing, with a minimal requirement for sequen

300 MRSA isolates underwent whole-genome sequencing, with a pairwise single-nucleotide pol