ライフサイエンスコーパス: genome size

1 tory bowel disease and diabetes) and average genome size.

2 total number of genomes for a given maximum genome size.

3 ly follows family-specific scaling laws with genome size.

4 cations, incurring up to 7%-10% increases in genome size.

5 ximately 98% of known variation in organelle genome size.

6 factors leading to their drastically reduced genome size.

7 arriers that scale as the square root of the genome size.

8 between the length of conserved segments and genome size.

9 ew mutation and of potential rapid change in genome size.

10 isense transcripts reversely correlated with genome size.

11 ome) may be the main reason for an increased genome size.

12 undant, with this complexity proportional to genome size.

13 rms) and account for part of the increase in genome size.

14 cting TE expansion is a major determinant of genome size.

15 ria that evolved by drastic reduction of the genome size.

16 in size and to analyze any correlation with genome size.

17 assembly representing 90.7% of the predicted genome size.

18 rming to constraints associated with maximum genome size.

19 ble elements, the primary factor determining genome size.

20 assembly reaching over 86% of the estimated genome size.

21 ed rare beneficial insertions that increased genome size.

22 and functions that are under the control of genome size.

23 synonymous substitution rates, and microbial genome size.

24 in particle length, reflecting the increased genome size.

25 etitive DNA versus its deletion in governing genome size.

26 ld, to ensure the maintenance of their large genome size.

27 effective to use on organisms with different genome sizes.

28 that for multicellular species with similar genome sizes.

29 ng extreme morphological diversity and large genome sizes.

30 ve pressures span nearly the entire range of genome sizes.

31 artly explain the vast disparity in observed genome sizes.

32 agation, comprising 37 species with variable genome sizes (0.158-1.88 Gbp).

33 agineum was widespread and exhibited a small genome size (1 C = 0.34 pg), an annual life cycle, and g

34 In contrast, E. vulgare exhibited a larger genome size (1 C = 0.43 pg), a perennial lifecycle, less

35 contains a smaller capsid and has a reduced genome size (146 kb) compared to the CbK-like phages (20

36 Additionally, because of its large genome size (17 Gb), re-sequencing at sufficient depth o

37 me sequencing, due in part to their enormous genome size (20-30 Gb) and the highly repetitive nature

38 ntal processes have been hampered by a large genome size, a lack of available mutants, and an inabili

39 expansion is the result of both variation in genome size across fungal species and diversifying selec

40 Coronaviruses (CoVs) have the largest genome size among all RNA viruses.

41 l unique characteristics including the small genome size, an ethylene-independent fruit ripening proc

42 We found a strong correlation between genome size and amount of satellite underreplication.

43 tically distant and drastically different in genome size and architecture, Hodgkinia and Baumannia ha

44 nctional relationship between stomatal size, genome size and atmospheric CO2 may contribute to the di

45 explore three hypotheses: the correlation of genome size and chromosome number, the origin of modern

46 in an experimentally tractable animal whose genome size and complexity models that of humans.

47 Genome size and complexity vary tremendously among eukar

48 However, because of genome size and complexity, these tools have yet to be a

49 ncreased mutational burdens favoring reduced genome size and complexity.

50 ich tool or parameters to use for a specific genome size and complexity.

51 n panicoid grasses with >5-fold variation in genome size and different histories of polyploidy.

52 e with observed positive correlation between genome size and effective population size.

53 act particularly of transposable elements on genome size and evolution of virtually all eukaryotic or

54 rk that was a challenge because of its large genome size and few chromosomes (1C 9.76 pg; n = 8).

55 merged for the scaling of mutation rate with genome size and for the likely mechanisms that drive thi

56 rian was accompanied by extreme reduction in genome size and gene content.

57 ctional categories outlined in (i) and (ii), genome size and gene density, indicating that these numb

58 Increases in genome size and gene losses are the consequences of this

59 s that are characterized by major changes in genome size and genome structure, such that these traits

60 he host is reflected in its relatively large genome size and high percentage of signal transduction g

61 etween symbiont function, transmission mode, genome size and host dependence.

62 m-positive hosts that are similar to SPO1 in genome size and in composition and organization of genes

63 The growing interest in genome size and increasing rate of data accumulation has

64 The rate is proportional to the genome size and inversely proportional to transposase ex

65 n of increased chemical stability, increased genome size and irreversibility.

66 ng lack of correlation between an organism's genome size and its morphological complexity.

67 d, in part, by a trade-off between bacterial genome size and local variation in climatic conditions.

68 Intriguingly, variation in genome size and many quantitative traits are significant

69 by the strongly inverse relationship between genome size and mutation rate across all replication sys

70 Yet the relationship between genome size and natural selection remains poorly underst

71 e capsid and C-terminal tails determines the genome size and nucleocapsid stability.

72 hotosynthetic organism to date, based on the genome size and number of genes in the reconstruction.

73 th positively selected sites was a result of genome size and number of mutations and positively selec

74 atic monocot with highly reduced morphology, genome size and number of protein-coding genes.

75 The small genome size and number of proteins encoded by these viru

76 ukaryote genomes and can dramatically change genome size and organization.

77 e) 5S and 35S rDNA units, chromosome number, genome size and ploidy level.

78 sure mutation rates in microbes with unusual genome sizes and life cycles.

79 earliest land plants had exceptionally large genome sizes and that a predicted overall trend of incre

80 imilar, despite the huge difference in their genome sizes and the different number of WGDs each genom

81 The evolution of mutation rate, genome size, and chromosome structure can therefore be e

82 ast differences in taxonomic classification, genome size, and radioresistance between cell types stud

83 eveal important changes in genome structure, genome size, and replication/gene regulation strategy du

84 Vertebrates exhibit substantial diversity in genome size, and some of the largest genomes exist in sp

85 proliferation likely contributed to a large genome size, and suggest that differences in copy number

86 C reliably estimated the species number, the genome size, and the relative abundance of each species,

87 ntal relation between mutation rate, maximal genome size, and thermodynamic response of proteins to p

88 re, small size, short generation time, small genome size, and wide geographic distribution make it an

89 he accuracy of the estimated species number, genome sizes, and percentages of correctly assigned read

90 nonautonomous retrotransposon replication on genome size appears to be much greater than previously a

91 divergent B. heracleifolia population with a genome size approximately 10% larger than the species me

92 nthus annuus L.), especially given its large genome size ( approximately 3.5 Gb) and the well-documen

93 Genome sizes are 4.13 Gb in aardvark, 4.01 Gb in African

94 ions fit the model that differences in plant genome sizes are largely explained by transposon inserti

95 microbial genomes, including GC content and genome size, are known to vary widely among different ba

96 Our results support genome size as a broad indicator of the growth behavior

97 A; this loss was followed by an expansion of genome size as a consequence of activity of transposable

98 f invaders of more open habitats, supporting genome size as a robust indicator of invasiveness.

99 significant positive correlation between the genome size, as well as gene size, and selective pressur

100 not all, display marked increases in overall genome size because of a proliferation of retrotransposo

101 predicted to cause substantial variation in genome size between species.

102 active enzymes, despite a large expansion in genome size, both of which are consistent with what is s

103 ments in a genome tends to increase with the genome size; (c) the flanking regions of the recently ac

104 earrangements, but most of the difference in genome size can be attributed to hundreds of thousands o

105 ults reveal that the evolution of eukaryotic genome size can be described by a simple proportional mo

106 yploidy) in angiosperms, although subsequent genome size change and diploidization (returning to a di

107 ling approach to study the directionality of genome size change in Gossypium.

108 osing forces and hence the directionality of genome size change remains unknown.

109 As genome size changes from megabases to gigabases, we pred

110 the three organisms have markedly different genome sizes, chromosome architecture and gene organizat

111 Finally, genome size constraints have driven the evolution of res

112 In this study, we analyse genome size data and chromosome numbers in a phylogeneti

113 atter include (i) a tool to visually compare genome size data between species, (ii) the option to exp

114 Genome size data have numerous applications: they can be

115 respectively, in the number of species with genome size data, compared with previous releases.

116 respectively, in the number of species with genome size data, compared with previous releases.

117 To achieve this, we generated new genome size data, increasing the percentage of fern spec

118 he least-squares statistics also scale up to genome-sized data sets with many nucleotides and loci.

119 Two plant genome size databases have been recently updated and/or

120 However, the simulation of genome-size datasets as produced by next-generation sequ

121 high levels of neopolyploidization, follows genome size decrease, stabilization, and genetic diploid

122 Advantages range from increasing genome size despite high mutation rates, faster replicat

123 consistent with our observed distribution of genome size determined by flow cytometry, which is skewe

124 Much of the genome size difference could be accounted for by non-cod

125 enic regions, with no evidence of the global genome size difference.

126 s (TEs) are often the primary determinant of genome size differences among eukaryotes.

127 d two cultivated Oryza species explain major genome size differences between sativa and brachyantha.

128 andem repeats) are primarily responsible for genome size differences between species.

129 Here, by fitting the genome size distributions in multiple groups of prokaryo

130 In contrast, genome size divergence between allopolyploids is manifes

131 For genome-size DNA, individual single T4 DNA is visualized

132 , the effects of crowding on the dynamics of genome-sized DNA are poorly understood.

133 dely debated effects of cellular crowding on genome-sized DNA.

134 can vary by several orders of magnitude, yet genome size does not correlate with the number of genes

135 olved in pathogenesis and shows an increased genome size due to transposable elements proliferation.

136 In particular, despite its small genome size, E. chaffeensis has four tandem virB6 paralo

137 o estimates of DNA sequence data quality and genome size early in the Human Genome Project, estimates

138 The duplicated genome size enlarged bark and wood layers in twigs sampl

139 ing mammal and avian evolution, resulting in genome size equilibrium.

140 With a nuclear genome size estimated at ~620 Mb, the cowpea genome is a

141 creasing the percentage of fern species with genome sizes estimated to 2.8% of extant diversity, and

142 r effective gas diffusion [3], as well as to genome size evolution [5, 6], major questions persist co

143 ere, we use digital evolution to investigate genome size evolution by tracking genome edits and their

144 Such extreme contrasting profiles of genome size evolution illustrate the key role of transpo

145 tutions, insertions, and deletions influence genome size evolution in asexual organisms.

146 dings support a unified "accordion" model of genome size evolution in eukaryotes whereby DNA loss cou

147 k, the data here confirm the conclusion that genome size evolution reflects many forces that collecti

148 ansposable elements (TEs) in relation to the genome size evolution.

149 size, we still do not understand what drives genome size evolution.

150 change is the dominant and universal mode of genome-size evolution in eukaryotes.

151 ransposons, comprise the primary vehicle for genome size expansion in plants, while DNA removal throu

152 ding sequences between genes, likely driving genome size expansion in the latter.

153 organization caused by DNA rearrangements or genome size expansion.

154 ionally hazardous, but weakly enough so that genome-size expansion passively emerges in species exper

155 splay massive retrotransposon proliferation, genome-size expansion, and gene losses.

156 the mitochondrion was not a prerequisite for genome-size expansion.

157 itative PCR approach, we estimated a haploid genome size for Basidiobolus at 350 Mb.

158 The core genome size for the B. cereus s.l. group was approximate

159 blies cover 91.6% and 82.2% of the estimated genome sizes for C. olitorius and C. capsularis, respect

160 We estimated genome sizes for the 12 sequenced Drosophila species as

161 st decade have made it possible to construct genome-size fragments from oligonucleotides.

162 f the four groups has its own characteristic genome size, GC ratio, and greatly expanded core gene co

163 that the endosymbionts are variable in their genome size, gene composition, and compounds they synthe

164 viral genomes with diverse genome structure, genome size, gene content and hosts.

165 As a consequence of its restricted genome size, genes that are highly conserved in other ba

166 r of errors becomes significantly higher for genome sizes greater than approximately 10 gigabases.

167 nome assembly, as coverage of sequencing and genome size growing, most current softwares require a la

168 It is still an open question as to whether genome size (GS) variation is shaped by natural selectio

169 Angiosperm genome sizes (GS) range c. 2400-fold, and as nucleic aci

170 iversity between these STs in terms of their genome sizes, guanine-cytosine (GC) content, intron numb

171 During eukaryotic evolution, genome size has increased disproportionately to nuclear

172 ly recent evolutionary innovation, but their genome sizes have diversified remarkably since their ori

173 Genome sizes have evolved to vary widely, from 250 bases

174 erall characteristics of a genome, including genome size, heterozygosity rate and repeat content from

175 ed and 16 real datasets with a wide range in genome sizes, heterozygosity levels and error rates.

176 compared to animal genomes due to the large genome sizes, high repetitive sequence content, and ramp

177 iverse microbial clades trend towards larger genome size, higher genomic GC content, and proteins wit

178 The massive variation in genome size identified by flow cytometry seems largely t

179 t mutation rate is inversely correlated with genome size in asexual populations.

180 e Plant DNA C-values database, and GSAD, the Genome Size in Asteraceae database.

181 ot appear to correlate with the reduction in genome size in bats.

182 sitive relationship evident between cell and genome size in both animals and plants forms the basis o

183 sponsible for lineage-specific expansions of genome size in eukaryotes, especially in multicellular s

184 Genome size in mammals and birds shows remarkably little

185 ian dinosaur lineage, but was 7-19% of total genome size in ornithischian dinosaurs, suggesting that

186 nced, which may partly account for the large genome size in Parhyale.

187 nomes confirm the reconstructed white spruce genome size in the 20 Gbp range, and show broad synteny.

188 repetitive DNA, comprised 5-12% of the total genome size in the saurischian dinosaur lineage, but was

189 elation between host dependence and symbiont genome size in vertically, but not horizontally, transmi

190 Genome sizes in plants are remarkably diverse, with a 23

191 s resulted in allotetraploids with divergent genome sizes, including Nicotiana repanda and Nicotiana

192 garithmic reduction in titre was observed as genome size increased.

193 ansposable elements are the major drivers of genome size increases in plants.

194 iers are related to intraspecific changes in genome size, indicating major genome restructuring betwe

195 me, shows a strong inverse relationship with genome size, indicating that drift promotes genome reduc

196 The draft mango cp genome size is 151,173 bp with a pair of inverted repeat

197 The total genome size is 162,321 bp, with an inverted repeat (IR)

198 verse relationship between mutation rate and genome size is a result of the tradeoff between evolving

199 iploid, leading us to believe that the final genome size is at least 700 Mb.

200 The genome size is ca. 163 Mb with 19,222 predicted protein-

201 Prokaryotic genome size is constrained by bioenergetics.

202 Genome size is highly correlated to a number of phenotyp

203 Genome size is often correlated with plant growth and ec

204 We investigated the novel hypothesis that genome size is related to forest invasions through its a

205 Afrotheria genome size is reported to be over 50% larger than that

206 This remarkable variation in genome size is the outcome of complex interactions betwe

207 icum aestivum) has had a massive increase in genome size largely due to recent WGDs.

208 scribed to the Parcubacteria include reduced genome size, limited metabolic potential and exclusive r

209 een difficult to locate as a result of large genome sizes, limited power of genetic identification sc

210 We find most cpDNA in genome-sized linear molecules, head-to-tail genomic conc

211 Due to its limited genome size, many genes conserved in other bacteria are

212 and this suggests that the forces dictating genome size may vary across the phylum.

213 We complement these data with genome size measurements, comprehensive analysis of S-ph

214 nomic analyses to investigate the diversity, genomes sizes, metabolic capacities, and potential roles

215 ral features potentially related to cell and genome size minimization include tightly packed spirals

216 s with variant C-terminal length, an optimal genome size minimizes an appropriately defined thermodyn

217 networks among six bacteria that have varied genome sizes (Mycoplasma pneumoniae, Treponema pallidum,

218 ther directly associated with an increase in genome size nor is there a general lineage-specific cons

219 ameters are discussed here, number of bases (genome size), number of chromosomes (karyotype), number

220 Reduction in the AtDt genome size occurred after allopolyploidization.

221 67 core proteins and a paralog-collapsed pan-genome size of 11,694 proteins.

222 contigs, closely approximating the estimated genome size of 140 Mb.

223 8000 Mb for Entomophaga aulicae, with a mean genome size of 37 Mb.

224 bp, compared to the predicted effective mean genome size of 4.74 Mbp for soil bacteria.

225 N50 scaffold size of 464 955 bp (based on a genome size of 606 Mbp), 221 640 contigs and a GC conten

226 ighly divergent (15.1 megabases of the total genome size of 61.1 megabases).

227 r data suggest an abundance that exceeds the genome size of Arabidopsis.

228 With an estimated genome size of around 1.5 Mbp, the genomes of Hadesarcha

229 the white lupin genome, using the predicted genome size of Lupinus angustifolius as a reference.

230 The large genome size of many species hinders the development and

231 The genome size of O. punctata was estimated to be 8% larger

232 The genome size of P. spumarius was estimated by flow cytome

233 homoeologous genes, together with the large genome size of polyploid wheat, had hindered genomic ana

234 The limited genome size of small viruses has driven the evolution of

235 omatin explains the approximately 75% larger genome size of sorghum compared with rice.

236 We show that an extraordinarily large genome size of tea tree is resulted from the slow, stead

237 The genome size of the hot pepper was approximately fourfold

238 e observed to have approximately doubled the genome size of Zea luxurians relative to Zea mays and Ze

239 use nutrient additions decreased the average genome sizes of the bacterial community members and elic

240 The genome sizes of these prophages range from 22.6-33.0 Kbp

241 However, the effect of vector genome size on titre has not been determined.

242 s differ dramatically in relative abundance, genome size, organization, and gene content.

243 lthough GH28 copy number was correlated with genome size, our findings suggest that ecological strate

244 atment were negatively correlated with total genome size (Pearson r < -0.9; p < 0.0001) and adjacent

245 mato, which is consistent with the increased genome size per haploid genome of these two Solanum spec

246 Due to their small genome size, picornaviruses must utilize host proteins t

247 rlying biology and data structure, including genome size, positional clustering of transcription fact

248 t duplication to loss ratio, correlates with genome size, potentially explaining increased abundance

249 Genome size, protein content, %GC, and repetitive DNA al

250 Their smaller genome sizes provide an opportunity to interrogate evolu

251 Genome sizes ranged from 1.491 to 1.716 Mb; GC contents

252 Owing to the very large genome sizes ranging from 18 to 35 gigabases, sequencing

253 Ancestral genome size reconstruction revealed that the most recent

254 ptional by themselves because of their small genome size, reduced metabolic flexibility, and high wor

255 eir nonmangrove relatives; as a consequence, genome size reduction happens independently in all six m

256 ae has been characterized by a trend towards genome size reduction, with just one episode of dramatic

257 ae has been characterized by a trend towards genome size reduction, with just one episode of dramatic

258 ) that the vast majority of the variation in genome size reflects the dynamics of proliferation and l

259 strated to reliably predict species numbers, genome sizes, relative species abundances, and k-mer cov

260 omosome numbers (aneuploidy and polyploidy), genome size, (retro)transposable element mobility, inser

261 Estimations of genome size reveal that myxozoans have one of the smalle

262 o (Ma), and acquired a twofold difference in genome size, revealed extensive local conservation of ge

263 res relative to green alga mtDNAs--increased genome size, RNA editing, intron gains, and gene losses-

264 e eukaryotic--and plant and algal--lineage a genome-sized sample of genes from the proteobacterial an

265 pontaneously produce variants that differ in genome size, sequence, and biological activity.

266 As a consequence of an expansion in genome size, some microbial eukaryotes with large N(e) a

267 However, maximum genome size steadily increases from the Mississippian (c

268 ecies-specific biases such as differences in genome size, strength of signal enrichment and co-occurr

269 n on the major components that contribute to genome size, such as transposable elements and gene dupl

270 trast, genic CHG methylation correlates with genome size, suggesting that the host epigenetic respons

271 ations via transposition and contributing to genome size, TEs play key roles in chromosome architectu

272 as they produce high yields and have a small genome size that facilitates their genetic manipulation.

273 anochromosomes ( approximately 50 Mb haploid genome size) that vary from 469 bp to 66 kb long (mean a

274 d cells as a proxy to track changes in plant genome size through geological time.

275 ength and use these data to infer changes in genome size through the evolutionary history of land pla

276 We estimate the genome size to be 728 Mb with 19,362 protein-coding gene

277 We used new measurements of genome size to evaluate its association with spring budb

278 Examination of the significance of genome size to plant invasions has been largely restrict

279 e of encoded transposases (>650) relative to genome size, together with the RAGEs and other MGEs, com

280 In Gossypium (cotton), the 3-fold genome size variation among diploids is due largely to c

281 In contrast, intraspecies genome size variation seems to be controlled by chromoso

282 natural selection, artificial selection and genome size variation, but likely not by polyploidizatio

283 , different ploidy levels and over threefold genome size variation, constitutes an ideal experimental

284 By investigating the drivers of genome size variation, we find that the larger Tripsacum

285 Eukaryotic genome size varies over five orders of magnitude; howeve

286 Genome sizes vary by several orders of magnitude, driven

287 Plants exhibit an extraordinary range of genome sizes, varying by > 2000-fold between the smalles

288 brary equivalent to 8-9 times of the haploid genome size was constructed for the weedy rice.

289 Genome size was correlated with chromosome number across

290 some of these evolutionary factors influence genome size, we still do not understand what drives geno

291 Genome sizes were assessed using flow cytometry in 79 sp

292 * Genome sizes were assessed using flow cytometry in 79 sp

293 (1.5% versus 53 to 59%), and differences in genome sizes were mainly due to variations in intergenic

294 itive organisms also possessed smaller total genome sizes, which could also have reduced their suscep

295 ions offset the costs associated with larger genome size while retaining adaptive substitutions.

296 s, in a microcosm, the overall difference in genome size, with a nearly twofold difference in aligned

297 ceae are the most diverse family in terms of genome size, with C-values ranging more than 230-fold.

298 ceae are the most diverse family in terms of genome size, with C-values ranging more than 230-fold.

299 content showed a quadratic relationship with genome size, with the decreases in GC content in larger

300 that a predicted overall trend of increasing genome size within individual lineages through geologica

301 plains the skewed distribution of eukaryotic genome sizes without invoking strong selection against l