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1  nickase enzyme that recognizes a 7-bp motif genome-wide.
2 scrimination against unfavorable AUG context genome-wide.
3  inter-chromosomal interaction patterns from genome-wide 3C studies are accurately captured in our mo
4                            This revealed the genome-wide accumulation of mutations in the resistant p
5            Here, we propose SCALE to analyze genome-wide allele-specific bursting, with adjustment of
6                                              Genome-wide analyses further revealed global DNA hypomet
7                            Collectively, our genome-wide analyses implicate condensin in the suppress
8                          Many cost-effective genome-wide analyses of DNA modifications rely on restri
9                                       Recent genome-wide analyses of human mRNA transcriptome identif
10 ng methylation states are critical to enable genome-wide analyses.
11  predictor can be easily used to conduct the genome-wide analysis and the results obtained are quite
12                                              Genome-wide analysis identified rs2457564 as a variant a
13                                              Genome-wide analysis of 5-hmC-enriched loci with hmC-sea
14                                    Through a genome-wide analysis of DNA methylation across 19 cell t
15  maintenance in CD8(+) T cells, we performed genome-wide analysis of DNA methylation, histone marking
16 roughput sequencing of diverse tissues and a genome-wide analysis of Dsx-binding sites.
17                                    We report genome-wide analysis of gene expression, DNA methylation
18                           In the course of a genome-wide analysis of members of a small family of imm
19             This result is consistent with a genome-wide analysis of S. cerevisiae, which reveals tha
20                           Here, we present a genome-wide analysis of single-nucleotide polymorphism (
21 fection, we have carried out a comprehensive genome-wide analysis of the fitness determinants for gro
22                                              Genome-wide analysis of the transcribed strand/nontransc
23                                              Genome-wide analysis shows that nonecotropic replacement
24 -seq to identify aberrant DNA-binding events genome wide and ectopic transcriptional consequences of
25                            We fit this model genome wide and profile the enzymatic activity of RNA po
26                                      Using a genome-wide approach, we demonstrate that inhibition of
27                                              Genome-wide approaches indicated that LMO2 is required a
28 enes selected for their roles in cancer, and genome-wide assays that broadly analyze the tumor exomes
29 sing summary data from the largest RA and AD Genome Wide Association (GWA) and meta-analysis studies
30                          As part of a recent genome wide association study (GWAS) to identify novel l
31 ociation studies and applied them to a large genome wide association study of BMD.
32 shapes traits, especially through the use of genome-wide association (GWA) analyses.
33 nd genetic research opportunities, including genome-wide association (GWA) analysis.
34                                              Genome-wide association (GWA) studies have identified 19
35 THODS AND Two-sample MR was undertaken using genome-wide association (GWA) study data.
36 izing 10,422 reference haplotypes to perform genome-wide association analyses and observe 17 genome-w
37                                 We performed genome-wide association analyses for twenty serum biomar
38 lth record (EHR)-based phenotypes allows for genome-wide association analyses in thousands of traits
39               Here, we report the results of genome-wide association analyses of multiple phenotypes
40         We report single- and multiple-trait genome-wide association analyses of self-reported sleep
41                                              Genome-wide association analyses were performed in pedia
42                                              Genome-wide association analysis (GWAS) identified genom
43                               We conducted a genome-wide association analysis (GWAS) to identify gene
44                                              Genome-wide association analysis and replication in 12,5
45                                              Genome-wide association analysis indicates that all comp
46                        We then carried out a genome-wide association analysis on these traits and the
47                                        Using genome-wide association analysis, we identify associatio
48 A5, TYRP1, SMARCA2/VLDLR, and SNX13, using a genome-wide association approach complemented by targete
49 types has not been tested previously using a genome-wide association approach.
50        Here we perform a meta-analysis of 11 genome-wide association case-control data sets, totallin
51                                      Through genome-wide association discovery in 48,943 individuals,
52                              METHODS & Using genome-wide association meta-analyses in up to 159,940 i
53 onducting sample-size-weighted fixed-effects genome-wide association meta-analyses in up to 9,594 wom
54 gramplusC4D) consortium's 1000 genomes-based genome-wide association meta-analysis (N = up to 184305
55                               We conducted a genome-wide association meta-analysis of IOP and optic d
56 otide polymorphisms (SNPs) identified from a genome-wide association meta-analysis of serum calcium l
57                                   Previously genome-wide association methods in patients with classic
58        The urine albumin-to-creatinine ratio genome-wide association scan identified associations wit
59                                   Multilocus genome-wide association studies (GWAS) have become the s
60                      During the past decade, genome-wide association studies (GWAS) have been used to
61                 Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >
62                                     Previous genome-wide association studies (GWAS) have identified 1
63                                     Previous genome-wide association studies (GWAS) have identified s
64                                              Genome-wide association studies (GWAS) have not identifi
65                                              Genome-wide association studies (GWAS) have played an im
66                                              Genome-wide association studies (GWAS) have transformed
67 bility variants have been identified through genome-wide association studies (GWAS) of predominantly
68                                         Most genome-wide association studies (GWAS) of QT were perfor
69                             In comparison to genome-wide association studies (GWAS), there has been p
70               In this review, we discuss how genome-wide association studies (GWASs) and recent devel
71                                       Recent Genome-wide Association Studies (GWASs) for eye diseases
72                                              Genome-wide association studies (GWASs) have identified
73                           A meta-analysis of genome-wide association studies (GWASs) identified multi
74                                              Genome-wide association studies (GWASs) implicate the PH
75                          Recent successes in genome-wide association studies (GWASs) make it possible
76 etic predictors of inflammatory markers from genome-wide association studies and applied them to a la
77 proved mmLD method will be useful for future genome-wide association studies and genetic association
78 NPs) on the panel from previous studies, and genome-wide association studies by using FarmCPU R packa
79               Interpretation of results from genome-wide association studies for T2D is challenging.
80                          Combining data from genome-wide association studies from multiple phenotypes
81                                              Genome-wide association studies have identified at least
82                                              Genome-wide association studies have implied the associa
83                                              Genome-wide association studies have revealed an associa
84                                              Genome-wide association studies identified numerous dise
85                                       Recent genome-wide association studies identified over 100 gene
86                                              Genome-wide association studies in frontotemporal dement
87                                  We explored genome-wide association studies of chronic lymphocytic l
88  193 CpGs with an enrichment of signals from genome-wide association studies of lipid levels (PTC=0.0
89                                         Most genome-wide association studies of this trait have been
90                                              Genome-wide association studies of tumor samples have id
91                           We meta-analyzed 2 genome-wide association studies on self-reported allergy
92 ntified 14,059 segregating polymorphisms and genome-wide association studies revealed 28 GWAS hits in
93                Among the participants in the genome-wide association studies, 21 loci jointly influen
94 proximately 4200 common variants reported in genome-wide association studies, approximately 1000 de n
95 s (SNPs), the most common genetic markers in genome-wide association studies, are usually in linkage
96 entifying response-associated genes in large genome-wide association studies, the results have been f
97 mmary association results from 7 large-scale genome-wide association studies, we examined the effect
98 P (rs964184) for triglycerides identified by genome-wide association studies.
99  were associated with 100 genetic loci using genome-wide association studies.
100 tives to the standard univariate analysis in genome-wide association studies.
101  AAA risk loci using data from all available genome-wide association studies.
102  case-control status have been replicated by genome-wide association studies.
103 ntial heritability not explained by previous genome-wide association studies.
104                                  The initial genome-wide association study (GWAS) included 174 Finnis
105 ther fields in terms of gene discovery using genome-wide association study (GWAS) methods.
106 s of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individua
107                               We conducted a genome-wide association study (GWAS) of alcohol consumpt
108 Biobank sample (N=108 976), we carried out a genome-wide association study (GWAS) of responses to the
109                         Based on our initial genome-wide association study (GWAS) on esophageal squam
110                                            A genome-wide association study (GWAS) predicted additiona
111                              The majority of genome-wide association study (GWAS) risk variants resid
112                               In contrast to genome-wide association study (GWAS), genomic prediction
113                                            A genome-wide association study across all VNB isolates re
114                                         This genome-wide association study analyzed criterion counts
115                  Here, the authors perform a genome-wide association study and identify an associatio
116 lymorphisms for schizophrenia in the largest genome-wide association study conducted to date suggeste
117                We conducted meta-analyses of genome-wide association study data on 2080 cannabis-depe
118                       We performed the first genome-wide association study for molar shape and used 3
119                               We performed a genome-wide association study for VTE with approximately
120 d then validated significant SNPs in another genome-wide association study from Harvard University.
121                  Using data from a published genome-wide association study from The University of Tex
122                                            A genome-wide association study identified LMO1, which enc
123                             This multicohort genome-wide association study identified new genomic loc
124                               We performed a genome-wide association study in 1001 healthy participan
125 onses to an acellular pertussis vaccine by a genome-wide association study in mice.
126                We conducted a cross-disorder genome-wide association study meta-analysis to identify
127                                       From a genome-wide association study of 16,596 individuals of E
128                                         In a genome-wide association study of 19,219 individuals, we
129 ci underlying LBM, we performed a gene-based genome-wide association study of lean mass index (LMI) i
130 om a case and control sample, we conducted a genome-wide association study of usual daily methadone d
131    We also conducted meta-analyses using the genome-wide association study results from the CTD cohor
132 s applied to two large Caucasian and Chinese genome-wide association study summary datasets of bone m
133                  We conducted an exploratory genome-wide association study to identify single-nucleot
134                  Genotyping, imputation, and genome-wide association study were performed at each stu
135                     We therefore performed a genome-wide association study with a dimensional, PD/AG-
136                                    Through a genome-wide association study, we report the identificat
137 oaches that can be used to test for GxE in a genome-wide association study.
138 i for fiber-quality-related traits through a genome-wide association study.
139                                        Using genome-wide association, we identified Tnni3k as one gen
140                        We report significant genome-wide associations at 14 loci.
141             None of our loci overlapped with genome-wide associations for asthma, although one locus
142          In this study, we provide the first genome-wide, base pair-resolution map of 6mA in Tetrahym
143  this study examined longitudinal changes of genome-wide blood DNA methylation profiles in relation t
144 lity of aneuploid fetuses is affected by the genome-wide burden of slightly deleterious variants.
145                         Here, we examine the genome-wide, C(5) -Methyl-cytosine (m5C) methylome and i
146                We investigated the impact of genome-wide cardiac DNA methylation on global gene expre
147                        The prion form caused genome-wide changes in the transcriptome.
148 elucidating drug resistance mechanisms using genome-wide chemical mutagenesis allied to next-generati
149 each time point demonstrated that changes in genome-wide chromatin accessibility were similar across
150                                              Genome-wide chromatin immunoprecipitation-sequencing ana
151 rformed on an Illumina platform, followed by genome-wide chromosomal copy number variation profiling
152 developed eight gene association methods for genome-wide coexpression analysis between each TF and al
153                         To date, however, no genome-wide comparisons have been performed to provide a
154                                              Genome-wide correlation studies have revealed that histo
155                            We have assembled genome-wide data from 19 ancient individuals, including
156 search and service groups to analyze typical genome-wide datasets being generated by H3Africa researc
157 build a web-based computational tool for the genome-wide detection of AARS coding sequences.
158 aviolet radiation, revealing their nonrandom genome-wide distribution.
159 ese same habitats, we also found significant genome wide DNA methylation differences.
160  DNA methylation in MS patients, by assaying genome-wide DNA methylation and comparing smokers, forme
161            We tested for association between genome-wide DNA methylation in WBCs and total IgE levels
162                                              Genome-wide DNAm profiles in individuals with CHARGE and
163 ynamics, massive accumulation of DNA damage, genome-wide double-strand breaks enriched at Ssb-binding
164 k scores (PRSs) have successfully summarized genome-wide effects of genetic variants in schizophrenia
165 e predictions of the GNM correlate well with genome-wide experimental measurements.
166 iction of clinical phenotypes using baseline genome-wide expression data that makes use of prior biol
167                                              Genome-wide expression of lncRNAs and mRNAs was determin
168                             Because of their genome-wide expression patterns in a variety of tissues
169    Fine mapping analysis by integration with genome-wide expression QTLs (eQTLs) from the same BC pop
170           We found that approximately 50% of genome-wide expression variability is explained by varia
171                               Furthermore, a genome-wide forward screen with Haplobank identified PLA
172 e results show that cohesin has an essential genome-wide function in mediating long-range chromatin i
173                          Here we developed a genome-wide functional screen to interrogate the transcr
174                            Transcriptome and genome-wide GABP-binding site analyses identify GABP dir
175                                      We used genome-wide gene expression analysis in clinical samples
176                     Here, we use an unbiased genome-wide genetic screen in near-haploid human cells t
177                                            A genome-wide genetic structure analysis of southern Afric
178               We compiled publicly available genome-wide genotype data on 5,966 individuals from 282
179 s with established psychiatric diagnoses and genome-wide genotype data.
180                          Here, we integrated genome-wide genotype, gene expression, viremia level, an
181                                              Genome-wide genotypes were imputed to the 1000 Genomes r
182                                        Using genome-wide haploid genetic screens, here we identify th
183 oposed a random regression model to estimate genome-wide imprinting effects on the relative growth of
184 ch colocalizes with histone H3K4 methylation genome-wide in human cells, mouse embryonic stem cells,
185 owing us to map autonomous promoter activity genome-wide in K562 cells.
186                                 However, the genome-wide intensity of this selection is not exception
187                                 We performed genome-wide interaction analyses between genetic variant
188                                          The genome-wide investigation of DNA methylation levels has
189 pressed in the polarized tissues, leading to genome-wide Irx3(+) caudal-polarization signals.
190  such projects as FANTOM and ENCODE, forming genome-wide landscapes in a series of human cell lines.
191                               We conducted a genome-wide linkage and association study in three Europ
192                           Candidate gene and genome-wide linkage studies have not significantly contr
193 ouring a BRCA mutation or high percentage of genome-wide loss of heterozygosity.
194 l single-guide RNA libraries, we conducted a genome-wide loss-of-function genetic screen in an isogen
195 udy, we present the first quantitative human genome-wide map of DNA lesions induced by ultraviolet (U
196 nce-driven saturation mutagenesis revealed a genome-wide map of the genetic determinants of plant roo
197 ortance of 5hmU, we develop a method for the genome-wide mapping of 5hmU-modified loci based on a che
198 (iPSCs) and hepatocyte-like cells (HLCs) for genome-wide mapping of expression quantitative trait loc
199                      At both time points the genome-wide mapping reveals that there is significant co
200                  Genomic selection (GS) uses genome-wide markers as an attempt to accelerate genetic
201                                 We present a genome-wide measurement of the order of splicing within
202                                    Combining genome-wide measures of DNA hydroxymethylation with comp
203 ding gene regulation and function requires a genome-wide method capable of capturing both gene expres
204 s single nucleotide polymorphisms (SNPs) and genome-wide methylation (methylation quantitative trait
205                              We characterize genome-wide methylation and highlight conserved motifs a
206                             Here, we compare genome-wide methylation patterns between isogenic ESC an
207                                              Genome-wide methylation profiles for different clones wi
208  we used a systems approach of integrating a genome-wide miRNA screen with patient-derived phospho-pr
209 ere low, relative to the large difference in genome-wide mismatching between the 2 groups.
210                  Here, we identify extensive genome-wide modification of sites bearing the active his
211 different inbred mouse strain to examine the genome-wide nuclear DNA methylation and gene expression
212 portunity to customize the classification of genome-wide nucleotide variant data most relevant to bio
213                                              Genome-wide occupancy mapping and transcriptome profilin
214               Moreover, the results from the genome-wide off-target assessments, compared with other
215 duces epigenetic reprogramming, by comparing genome-wide patterns of methylation and variation at the
216 rithms and conservation scores: including 13 genome-wide prediction algorithms and conservation score
217 enie (LEG), a collection of highly accurate, genome-wide predictions of enhancers in the developing l
218                                              Genome-wide profile analysis revealed that genes regulat
219 ications for T2D, we analyzed and replicated genome-wide protein coding variation in a total of 8,227
220           Our method is unbiased and scans a genome-wide protein-protein interaction network using a
221 n to the standard exome capture, we included genome-wide proximal promoter regions that contain seque
222                                           In genome-wide rate comparison studies, there is a big chal
223  and physical distances was examined and the genome-wide recombination rate was found to be much smal
224                                   We develop Genome-wide Reconstruction of Complex Structural Variant
225  of hundreds of enhancers along with drastic genome-wide reduction of HNF4A and HNF4G occupancy.
226                                  We examined genome-wide regulatory actions of ZNF764 on the glucocor
227 next-generation sequencing (NGS) to generate genome-wide repair maps.
228 iduals) and from the Coronary Artery Disease Genome-wide Replication and Meta-analysis Plus the Coron
229                                       Recent genome-wide ribosome profiling studies suggest that thou
230                                          Our genome-wide RNA compendium will allow for a better under
231           Here we have carried out the first genome-wide RNA-Sequencing study in human conjunctival f
232                               Here, we use a genome-wide RNAi-synthetic lethal screen and transcripto
233                  The interpretation of these genome-wide ROIs represents a challenge as the majority
234                                         At a genome-wide scale estimation of correlation matrices can
235               It is oftentimes unknown, at a genome-wide scale, how much transdifferentiated cells di
236                                       At the genome-wide scale, our data indicate that ATRX modifies
237                 Additionally, we performed a genome-wide scan and identified one SNP with significant
238                 We performed 2 high-density, genome-wide scans comprising 2345 cases of African Ameri
239 -dimensional image analysis, combined with a genome-wide screen for DELLA-bound loci in the infloresc
240       We test the model's predictions with a genome-wide screen for essential genes using a transposo
241 igh-fidelity DNA replication, we conducted a genome-wide screen in Saccharomyces cerevisiae using DNA
242 rfering with cyclins/CDKs, we performed nine genome-wide screens for human microRNAs (miRNAs) directl
243 PRko, CRISPRi and CRISPRa) in the context of genome-wide screens to identify components that influenc
244 es the research community with wild strains, genome-wide sequence and variant data for every strain,
245                                 We performed genome-wide sequencing and analyzed mRNA and miRNA expre
246       Taking advantage of recent advances in genome-wide sequencing approaches, Vo ngoc and colleague
247                                              Genome-wide sequencing data has enabled modern phylogeno
248 described in v78 (September 2016), combining genome-wide sequencing results from 28 366 tumours with
249                                       Recent genome-wide sequencing studies have identified frequent
250 ogramming-induced senescence, we performed a genome-wide shRNA screen in primary human fibroblasts ex
251             Two new signals were observed at genome-wide significance (P < 5 x 10-8), namely, rs72160
252                      No associations reached genome-wide significance (p>5 x 10(-8)).
253 212 is noteworthy (FPRP <0.2) and approaches genome-wide significance in multivariable analysis (P mu
254 rs2075291, in APOA5 associated with CAD at a genome-wide significance level and provided new insights
255 not identified maternal sequence variants of genome-wide significance that replicate in independent d
256                           No associations of genome-wide significance were detected for CD.
257  An SNP near integrin alpha6 (ITGA6) reached genome-wide significance with PA (P=1.80x10(-8)), wherea
258      This approach identified 13 new loci at genome-wide significance, 12 of which were on our previo
259      Three variants in locus ADAM12 achieved genome-wide significance, although they did not replicat
260 nalysis, we identified 22 loci associated at genome-wide significance, including 13 new associations
261 c analysis, which was underpowered to detect genome-wide significance, the evaluation being limited t
262 iated with both leucine and valine levels at genome-wide significance.
263  adjusted lung function, and 15q25.1 reached genome-wide significance.
264 ci associated with emphysema distribution at genome-wide significance.
265                      In our meta-analyses, 1 genome-wide significant association was detected: the ca
266                                            A genome-wide significant association was found between AC
267 AM13A in lung tissue, respectively; and were genome-wide significant in a meta-analysis including bot
268 ssociated with a functional variant that was genome-wide significant in our meta-analysis.
269 morphism (SNP) in TRACK-HD (rs557874766) was genome-wide significant in the meta-analysis (p=1.58 x 1
270                                         Near genome-wide significant interaction effect was observed
271   The identification and characterization of genome-wide significant loci for cannabis dependence is
272 -stratified analysis identified 2 additional genome-wide significant loci in females.
273                           We identified four genome-wide significant loci, none of which showed any a
274                   The authors identified one genome-wide significant locus on chromosome 12 (rs462230
275  progression in TRACK-HD and REGISTRY gave a genome-wide significant signal (p=1.12 x 10(-10)) on chr
276 a linear mixed model, identified three novel genome-wide significant signals on chromosomes 2, 11, an
277                                We report 106 genome-wide significant signals that have not been previ
278 on are associated with greater enrichment in genome-wide significant SNPs from the GWAS catalog, and
279 ome-wide association analyses and observe 17 genome-wide significant, independent signals, including
280 lele frequency <0.01, (rs3025380 at DBH) was genome-wide significant.
281                          Our high-throughput genome-wide siRNA screen identified host factors that pr
282                                              Genome-wide studies utilizing STARR-seq identified two e
283                         A recent large-scale genome-wide study from our group predicted transcription
284                                Additionally, genome-wide surveillance of inherited SVs reveals novel
285                                            A genome-wide survival analysis of 14,406 Alzheimer's dise
286 s for locating cis-regulatory modules (CRMs) genome-wide, the next pressing challenge is to assign pr
287                                  Here, using genome-wide transcription and genetic diversity analyses
288                                    Analyzing genome-wide transcription and repair by next-generation
289                                              Genome-wide transcription factors (TFs) binding data has
290 a overexpression substantially recapitulates genome-wide transcriptional profiles and alternative spl
291                                     Although genome-wide transcriptome analysis on diseased tissues h
292                                              Genome-wide transcriptome analysis reveals that lipid bi
293 ll regions of sequence and do not illustrate genome-wide trends, or are complicated to use and create
294                  By monitoring recombination genome-wide using cytological assays and at hotspots usi
295 ble us to quantify methylation stochasticity genome-wide using Shannon's entropy, associating it with
296                                              Genome-wide variation in P. leucopus indicates two post-
297 associated with AF, but the contributions of genome-wide variation to AF susceptibility have not been
298  landraces and wild species, we characterize genome-wide variation.
299 (117 g L(-1)), and L2 (76 g L(-1))-to gain a genome-wide view of the mechanism of citrate accumulatio
300 ntial to limit gene conversion tract lengths genome-wide, without affecting crossover formation.

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