ライフサイエンスコーパス: genomic information

1 e of approaches to the ethical management of genomic information.

2 actors come together to faithfully propagate genomic information.

3 ks, allowing us to integrate microscopic and genomic information.

4 e browser is a powerful aggregator of varied genomic information.

5 of a size that has the potential to transfer genomic information.

6 d escaping it requires the use of additional genomic information.

7 Base is a database of Drosophila genetic and genomic information.

8 alysis of nonmodel plants with less complete genomic information.

9 es, gene expression profiles and comparative genomic information.

10 reviously used for describing phenotypes and genomic information.

11 seriously handicapped by a lack of adequate genomic information.

12 scribed as the largest untapped reservoir of genomic information.

13 des directly from tissue extract without any genomic information.

14 tion which allows timely access to important genomic information.

15 merases that ensure accurate transmission of genomic information.

16 be reconstructed and optimized in vitro from genomic information.

17 mber of individuals with access to their own genomic information.

18 UTO, designed to apply clustering methods to genomic information.

19 the next logical step beyond storing purely genomic information.

20 of how to efficiently integrate all current genomic information.

21 oach represents an innovative application of genomic information.

22 SNPs will therefore facilitate the mining of genomic information.

23 e already enhancing the potential utility of genomic information.

24 potentiated by the availability of bacterial genomic information.

25 s to lose) from the private appropriation of genomic information.

26 updated to keep pace with the rapid rise in genomic information.

27 erse and carry varying copy numbers of their genomic information.

28 ints within nuclei and to regulate access to genomic information.

29 osome is important for the interpretation of genomic information.

30 and cope with the ever-increasing amount of genomic information.

31 haracterize and manipulate the regulation of genomic information.

32 iruses in the sample, and may provide useful genomic information.

33 ents and by difficulties in sharing personal genomic information.

34 ntation provides an indexed database of core genomic information.

35 wed us to characterize increasing amounts of genomic information.

36 lly by histopathology and currently based on genomic information.

37 eate the boundary of a genus on the basis of genomic information.

38 led to exponential increase in the amount of genomic information.

39 and gap filling largely without considering genomic information.

40 tations with the extensive ENCODE functional genomics information.

41 from sequences with experimental functional genomics information.

42 t improves the efficiency of the analysis of genomics information.

43 g is an important problem in the analysis of genomics information.

44 es that faithfully and efficiently replicate genomic information.1-3 The mechanism of nucleotide inco

45 Despite a wealth of genomic information, a comprehensive alternative splicin

46 These include detailed genomic information, a wealth of genetic models, and gen

47 The amount of genomic information about leukemia cells currently far e

48 tabase (CGD) is a new database that contains genomic information about the opportunistic fungal patho

49 is an international database for genetic and genomic information about Triticeae species (wheat [Trit

50 As genomic information accrues, the challenge remains to co

51 DNA evidence, thus limiting the value of the genomic information and also leaving unanswered certain

52 A paucity of biological, molecular, and genomic information and an absence of data from rigorous

53 abase (CGD) contains a curated collection of genomic information and community resources for research

54 scuss these data in the context of available genomic information and debates on whether the common ch

55 This will promote ready access to genomic information and fundamental technologies, while

56 S reveals it to be a nebulous description of genomic information and its relationship to disease, sym

57 logy of this disease, drawing from expanding genomic information and lessons from development and gen

58 Third, we discuss the merging of genomic information and physiological observations, reve

59 sents an important historical source of host genomic information and potentially of infecting viruses

60 h the increasing diversity and complexity of genomic information and public ontologies, making sense

61 This influx of genomic information and resources is also beneficial to

62 Using genomic information and the consensus AlgU promoter sequ

63 a pivotal role in both the accessibility of genomic information and the dynamics of replication.

64 required to accommodate this large volume of genomic information and to facilitate the transfer of pr

65 ever increasing wealth of publicly available genomic information and to utilize the tremendous progre

66 The method does not use any genomic information and unlike targeted methods, no prio

67 combining the multiple sources of functional genomics information and testing associations between th

68 d because of phylogenetic ambiguity, lack of genomic information, and their close associations with h

69 pedigrees, which includes both pedigree and genomic information, and where mutually dependent geneti

70 long as damage is present to prevent loss of genomic information; and after the arrest, cells must re

71 om genetic mutations and, therefore, loss of genomic information appears necessary for carcinogenesis

72 ing robust predictors of drug responses from genomic information are of great practical importance.

73 onality, list management tools and access to genomic information associated with the TFs.

74 of mouse models because of the high level of genomic information available and the many well-develope

75 was used to design new primers using current genomic information available from the National Center f

76 crobial samples and simultaneously accessing genomic information based on WGA.

77 Poliovirus has evolved to maximize its genomic information by producing multifunctional viral p

78 Similar strategies to integrate diverse genomic information can be applied likewise to other dis

79 es, akin to the way in which newly generated genomic information can be compared to data from public

80 These studies illustrate how genetic and genomic information can be exploited toward identifying

81 otion an avalanche of research exploring how genomic information can be optimally applied to identify

82 Our studies show how genomic information can be used to uncover on a global s

83 demonstrates how integration of genetic and genomic information can define molecular mechanisms thro

84 evelopment, and then we will analyze how the genomic information can help further our understanding o

85 Integration of these two types of genomic information can improve the prediction of TF bin

86 atory factors that control the expression of genomic information come in a variety of flavors, with t

87 me sequences described herein provide useful genomic information concerning millipede groups that had

88 a thorough consideration of the genetic and genomic information concerning the animals used as model

89 Here we show that the theoretical limit on genomic information content may increase substantially a

90 roenvironmental selection pressures preserve genomic information controlling properties that confer s

91 prone compared to DNA, suggesting that total genomic information could increase after the transition

92 eveloped a method (CompView) for integrating genomic information derived from available cytogenetic,

93 In principle, genomic information derived from tumors should illuminat

94 the airway field of injury and of using the genomic information derived to begin to answer some of t

95 eny and colinearity) and in the extension of genomic information directly from one grass species to a

96 ion genomics of nonhuman primates and expand genomic information directly relevant to primate models

97 n by neurosurgical procedures performed, and genomic information (e.g. apolipoprotein E and haptoglob

98 method called Enhancer Detection using only Genomic Information (EDGI), which integrates a tradition

99 This novel genomic information enables the search for polymorphisms

100 -fate transitions involve the integration of genomic information encoded by regulatory elements, such

101 atistical power is to incorporate functional genomics information, especially gene expression network

102 Because little genomic information existed for this species, we used 45

103 nal transcript sequences where limited prior genomic information existed, this work created part of t

104 t point to the glycome as a direct output of genomic information flow.

105 Ensembl integrates genomic information for a comprehensive set of chordate

106 lated to long non-coding RNAs (lncRNAs): (i) Genomic information for a large number of lncRNAs collec

107 le to provide public access to the collected genomic information for A. thaliana via the World Wide W

108 urnish anatomic, physiologic, molecular, and genomic information for accurate disease diagnosis, pred

109 ents an in silico model largely derived from genomic information for an organism for which there is s

110 c approaches together with the new wealth of genomic information for both human and model organisms o

111 accuracy, utility and acceptability of using genomic information for clinical care.

112 the utilization of functional and structural genomic information for genomic prediction and estimatio

113 roach to integrate functional and structural genomic information for genomic selection.

114 The availability of genomic information for hundreds of species enables the

115 LIS provides access to genetic and genomic information for major crop and model legumes.

116 f ancient duplications improve leveraging of genomic information for model organisms in the study of

117 In silica analysis of genomic information for P. fluorescens, P. putida, and P

118 hrough the logarithmically expanding seas of genomic information for polyketide compound discovery an

119 is to provide public access to the collected genomic information for R.sphaeroides via the World-Wide

120 Although genomic information for S. moellendorffii is starting to

121 not be readily linked with the proteomic and genomic information for studies in systems biology and m

122 sequences, three-dimensional structures and genomic information for the homeodomain protein family.

123 sequences, three-dimensional structures and genomic information for the homeodomain protein family.

124 s been updated to provide more comprehensive genomic information for the red flour beetle Tribolium c

125 as well as matched and standardized sets of genomic information for the sequenced aspergilli.

126 s a scientific database of gene, protein and genomic information for the yeast Saccharomyces cerevisi

127 (iii) it provides comprehensive comparative genomics information for comparing alternative splicing

128 nto a hierarchy and integrated it with other genomic information (for example, microRNA regulation),

129 eds.ac.uk/metatiger) has been created, using genomic information from 121 eukaryotes and 404 prokaryo

130 g approach and intelligence for interpreting genomic information from an individual case.

131 endly online research environment to explore genomic information from different plants.

132 It provides access to genomic information from extant species, as well as ance

133 lso establish a method to amplify and screen genomic information from extinct species, and place Biso

134 portunities associated with extrapolation of genomic information from facile models to large-genome t

135 the hypothesis that systematic knowledge of genomic information from individual tumors can improve c

136 The large amount of genomic information from recent sequencing efforts provi

137 Base is a system of databases focused on the genomic information from sea urchins and related echinod

138 Leveraging genomic information from sequenced to nonsequenced speci

139 In addition, we use genomic information from several species to draw inferen

140 n (WGA) make it difficult to derive accurate genomic information from single-cell genomes and require

141 r the reconstruction of TRMs that integrates genomic information from TF binding, cell type-specific

142 Our method rTRM predicts TRMs by integrating genomic information from TF ChIP-seq data, cell type-spe

143 nomics (SCG) are promising tools to retrieve genomic information from these uncultured organisms.

144 Genomic information from this study provides a valuable

145 Here, we increase the recovery of genomic information from two MAST-4 lineages by co-assem

146 SCG) appeared as a powerful technique to get genomic information from uncultured organisms.

147 esent models for the application in crops of genomic information gained in Arabidopsis and provide an

148 Genomic information gathered from across the biosphere,

149 biology and the wealth of publicly available genomic information guiding the identification of potent

150 Genomic information has already been applied to prokaryo

151 Host genomic information has also yielded insights into bacte

152 The amount of functional genomic information has been growing rapidly but remains

153 se in the amount and rate of accumulation of genomic information has created new challenges for the p

154 The cost of genomic information has fallen steeply, but the clinical

155 Although the raw genomic information has limitations, its availability of

156 rospective trials testing whether the use of genomic information improves clinical care are underway.

157 ill provide a useful paradigm for organizing genomic information in a biologically relevant manner.

158 By including additional genomic information in a multiple-threshold framework, w

159 Despite the wealth of genomic information in Arabidopsis and several crop plan

160 ill greatly benefit clinical applications of genomic information in diagnosis, prognosis and therapeu

161 The transcription of genomic information in eukaryotes is regulated in large

162 ere has not been widespread practical use of genomic information in everyday practice, there are many

163 and resequencing herald a rapid expansion of genomic information in heart failure.

164 and the value of comparative and functional genomic information in meeting that challenge.

165 cuss clinical research on the application of genomic information in oncology.

166 me has initiated the development of detailed genomic information in other birds including turkey, an

167 s essential for maintaining the integrity of genomic information in prokaryotes and eukaryotes.

168 through the pathways to favor protection of genomic information in regions of actively transcribed c

169 tous in Eukaryotes, comprising 50-90% of the genomic information in some cases.

170 To facilitate the use of genomic information in such studies, a new modeling pers

171 of the core and linker histones, as well as genomic information in the form of map loci for the huma

172 of the core and linker histones, as well as genomic information in the form of map loci for the huma

173 or maintaining and enhancing the use of this genomic information in the post-genomic era.

174 alysis and storage of annotated clinical and genomic information in unconnected silos will stall the

175 e homeodomain family play an important role; genomic information includes relevant gene symbols, cyto

176 Inheritance of genomic information independent of the DNA sequence, the

177 he novel features of the system include: (a) genomic information integrated with other biological dat

178 ian to make a clinical decision based on the genomic information integrated with other clinical featu

179 ve been accumulated in the public domain and genomic information integration and meta-analysis have b

180 from research to the clinic and to transform genomic information into better diagnosis and outcomes f

181 cine (IM), which aims to incorporate genetic/genomic information into medicine.

182 uracy and efficiency with which tRNA decodes genomic information into proteins require posttranscript

183 to discuss challenges related to translating genomic information into the clinic, and we present one

184 Predicting the best treatment strategy from genomic information is a core goal of precision medicine

185 A wealth of genomic information is available in public and private d

186 st outgroup of animals for which comparative genomic information is available.

187 Genomic information is becoming more abundant for many o

188 agnosis than to fetal treatment, genetic and genomic information is beginning to influence pregnancy

189 vioral features of cancer cells and how this genomic information is being exploited to improve diagno

190 conomic importance of Coffea species, little genomic information is currently available.

191 However, genomic information is dramatically lacking in this genu

192 Genomic information is encoded on a wide range of distan

193 NA duplication and separation, ensuring that genomic information is faithfully and perpetually mainta

194 should help clarify this point further once genomic information is gathered for other taxa of the fa

195 g new knowledge from the wealth of available genomic information is hindered, in part, by the difficu

196 However, obtaining bacterial genomic information is not always trivial: the target ba

197 This wealth of genomic information is not available anywhere else.

198 other lineage, is difficult to study because genomic information is often absent for long-extinct rel

199 Genomic information is rapidly accumulating for the huma

200 ies, further basic mutational and functional genomic information is required.

201 We found that complementary genomic information is retrieved from different SAGs, ge

202 To gain insight into how genomic information is translated into cellular and deve

203 only a very limited amount of plant trichome genomics information is available in scattered databases

204 e expression data, as one example of complex genomic information, is often under-appreciated as many

205 c engineering methods, along with increasing genomic information, makes heterologous expression of pr

206 etermine whether and how comprehensive tumor genomic information may become incorporated into the rou

207 This powerful combination of genomic information, molecular tools, and immunological

208 ase, a single sample may not contain all the genomic information necessary for treatment.

209 of microbial pathogens, but the increase in genomic information necessitates significant investment

210 We recently introduced the genomic information network (GIN) method for systematica

211 to maximize what we learn from the wealth of genomic information now available.

212 es, taking full advantage of the plethora of genomic information now available.

213 The amount of genetic and genomic information obtainable from the human fetus duri

214 Using genomic information of human breast cancer, we have disc

215 t sequences ('reads') is critical to extract genomic information of interest for further evaluation,

216 The genomic information of microbes is a major determinant o

217 ty draft genomes, it allows accessing to the genomic information of microbes that would otherwise rem

218 Extensive genomic information of Pol I has recently become availab

219 d without the need of any prior knowledge of genomic information of the living organism being studied

220 ieval, and data analysis, indexed around the genomic information of the organism of interest.

221 d in their attitudes about the disclosure of genomic information of uncertain significance.

222 trait locus (QTL) mapping, relatively little genomic information on M. spretus exists, and most of th

223 Finally, the accumulating datasets of genomic information on pregnant women and their fetuses

224 ding database and web portal for genetic and genomic information on the fruit fly Drosophila melanoga

225 ensive collection of sequence, structure and genomic information on the homeodomain protein family.

226 proteomic screen that can be correlated with genomic information on the same individuals.

227 Genomic information on tumors from 50 cancer types catal

228 out the mouse, but also provides comparative genomic information particularly for human and rat genom

229 to 99.7% of all participants' most sensitive genomic information private.

230 ernal organization enables them to behave as genomic information processing systems.

231 This genomic information provides a basis to expand understan

232 The genomic information provides insight into the diversity

233 With all genomic information recently updated to GRCh37, COSMIC i

234 a valuable resource for researchers seeking genomic information regarding the chicken and other avia

235 e technologies and the ensuing outpouring of genomic information related to cancer have accelerated t

236 enomic pilot study to evaluate the impact of genomic information related to colorectal cancer (CRC) r

237 Genomic information representing a fish lineage that div

238 astases and may provide much of the relevant genomic information required to guide treatment on recur

239 The rapid increase in genomic information requires new techniques to infer pro

240 lar changes improve outcome, indicating that genomic information should be incorporated into future t

241 The need to generate increasing amounts of genomic information should prompt health-care providers

242 Limited genomic information shows that phage genomes are mosaic,

243 The availability of genomic information significantly increases the number o

244 omes and allows users to upload self-defined genomic information so that they can visually study the

245 New developments in molecular biology, human genomic information, statistical methods, and bioinforma

246 fications and DNase I cleavage patterns with genomic information such as gene annotation and evolutio

247 sing an integrated work flow that uses other genomic information such as linkage regions, regions of

248 The analysis of large-scale genomic information (such as sequence data or expression

249 added to link the QTL data to other types of genomic information, such as radiation hybrid (RH) maps,

250 ng de novo transcriptome assemblies by using genomic information that can be partial or complete geno

251 cells intrinsically explore their available genomic information, the greater genomic landscape (GGL)

252 ng properties of proteins, given only simple genomics information: the chain length and the numbers o

253 tation of Driver-gene Inference by Genetical-Genomic Information Theory as an R-system package.

254 ubstantial interests have developed in using genomic information to define disease-mediating genetic

255 enome sequence, various groups have used the genomic information to identify and validate targets as

256 s and plants, we demonstrate that we can use genomic information to infer microbial traits that are d

257 Here we develop an approach for applying genomic information to predict alternative functions for

258 regarding the application of transcriptional genomic information to renal transplantation, with speci

259 st be overcome to apply rapidly accumulating genomic information to understand variable drug response

260 platforms, while remaining oblivious to the genomic information until the final alignment step.

261 Across the ~500 taxa for which genomic information was available, genomic traits were m

262 The genomic information was first used for the development o

263 With this additional genomic information, we are able to resolve many intra-

264 s metabolic, biochemical, physiological, and genomic information, we reconstructed an experiment-base

265 for analyzing this organism's metabolic and genomic information, which could lead to potential insig

266 ty, enormity, and rapidly changing nature of genomic information, which existing electronic health re

267 th marine geochemical evidence and microbial genomic information, which together suggest the existenc

268 e major issues raised by increased access to genomic information, which will ultimately be resolved b

269 Molecular phenotyping using genetic and genomic information will allow early and more accurate p

270 als, although it remains unclear whether DTC genomic information will still be attainable.

271 aches, fuelled by advances in immunology and genomic information, will facilitate the discovery of an

272 et healthy and diseased states by connecting genomic information with additional dynamic omics activi

273 We also find strong evidence that combining genomic information with clinical information improved t

274 nistic understanding requires integration of genomic information with complementary functional analys

275 ng the growing body of enzyme-structural and genomic information with computational methods to rapidl

276 dicine is expected to benefit from combining genomic information with regular monitoring of physiolog

277 ion of the data, and integrating comparative genomics information with alternative splicing data.

278 fer the possibility of incorporating updated genomic information without production of a new chip.

279 olecule sequencing enabled analysis of human genomic information without the need for cloning, amplif