ライフサイエンスコーパス: genomic region

1 enhancer markers were increased in the HKDC1 genomic region.

2 NA property, it is readily applicable to any genomic region.

3 phenotypic variation and encompassed 89.5 Kb genomic region.

4 e track of the total DNA population for each genomic region.

5 nd optionally comparing two parallel sets of genomic regions.

6 due to genetic variation in the transcribed genomic regions.

7 d capture the continuum of large and complex genomic regions.

8 verting DNA cytosines to uracils at specific genomic regions.

9 tors are co-expressed and target overlapping genomic regions.

10 re origins are chosen from a limited pool of genomic regions.

11 individuals' copy number profiles across the genomic regions.

12 Pea/faba bean CFN were associated to Rlv genomic regions.

13 the DNA methylation landscape of any set of genomic regions.

14 pacity, and maintenance of these conspicuous genomic regions.

15 cacy of natural selection on non-recombining genomic regions.

16 n detecting insertions in complex repetitive genomic regions.

17 s are informative, with low coverage in many genomic regions.

18 gher TE occurrence in immune gene-associated genomic regions.

19 erse evolutionary forces on trait-associated genomic regions.

20 ingle nucleotide polymorphisms in non-coding genomic regions.

21 hed in brain and in conserved and regulatory genomic regions.

22 Ps provide limited genetic information about genomic regions.

23 s evidenced by a gain of 520 and loss of 149 genomic regions.

24 alysis on nucleosome positioning data in all genomic regions.

25 s decode the modification status of specific genomic regions.

26 posit the histone variant H3.3 into specific genomic regions.

27 rtions frequently found in highly repetitive genomic regions.

28 udy genetic variation and undercharacterized genomic regions.

29 ith ICS and replicated previously identified genomic regions.

30 pectedly rich evolution of these challenging genomic regions.

31 nd eighteen signals of association at twelve genomic regions.

32 geting mitochondrial (COI) and nuclear (18S) genomic regions.

33 epletion of Neandertal ancestry in conserved genomic regions.

34 single-nucleotide polymorphisms and flexible genomic regions.

35 g quality varies across different functional genomic regions.

36 transcription or recruited in trans to other genomic regions.

37 n of oligonucleotides hybridized to selected genomic regions.

38 patterns across subjects and across multiple genomic regions.

39 as well as a series of chemotype-associated genomic regions.

40 s lost and accuracy is reduced in repetitive genomic regions.

41 ble the rapid visualization of many targeted genomic regions.

42 s to hyper-methylation at approximately 1000 genomic regions.

43 genome minimization and the removal of large genomic regions.

44 we propose to refer to this DNA as adaptive genomic regions.

45 Our admixture mapping analysis identified a genomic region (3p24.2) in which increased Native Americ

46 We examined the association between PDAC and genomic regions (+/-500 kb) surrounding established comm

47 atched white blood cell DNA covering a large genomic region (508 genes; 2 megabases; >60,000x raw dep

48 Strikingly, active genomic regions (A-type compartments, active chromatin,

49 We show that the average accessibility of a genomic region across training contexts can be a surpris

50 configuration brings active genes located in genomic regions adjacent to SAHDs in close spatial proxi

51 ensable genes are associated with hemizygous genomic regions affected by structural variants, which o

52 The goal of our study was to identify genomic regions affecting the predicted methane emission

53 Shared genomic regions among EC levels were identified on BTA 2

54 leotide polymorphisms (SNPs) in a particular genomic region and a drug response of interest.

55 K4me defines the transcriptional status of a genomic region and defends the genome from TRC-mediated

56 We mapped this trait difference to a single genomic region and, using third generation, long-read se

57 cipants, we discovered 106 new BP-associated genomic regions and 87 rare (minor allele frequency <= 0

58 falls of Patterson's D when applied to small genomic regions and accurately quantifies the fraction o

59 clusions are strongly supported by different genomic regions and are consistent with some morphologic

60 tromeres are among the most rapidly evolving genomic regions and can shape karyotype evolution and sp

61 hindering studies of DSB repair in different genomic regions and chromatin contexts.

62 atures at ZFIN include increased support for genomic regions and for non-coding genes, and support fo

63 s are enriched in evolutionarily constrained genomic regions and loss-of-function intolerant genes an

64 gmatic features for variable user-interested genomic regions and optionally comparing two parallel se

65 y of dental caries is enriched for conserved genomic regions and partially overlapping with a range o

66 improvement, allowing the prioritisation of genomic regions and particular sets of lines for breedin

67 been extended to include searches by genes, genomic regions and phenotypes, as well as for genetic v

68 lamus (ARH) reveal differentially methylated genomic regions and reduced expression of AgRP neuron-as

69 g the selective targeting to polycomb-marked genomic regions and synovial sarcoma-specific dependency

70 enables the study of previously inaccessible genomic regions and their epigenetic marks.

71 uct design, greater flexibility in targeting genomic regions, and cost-effective attributes have resu

72 opulation, assessing overlap with functional genomic regions, and genome-wide association analysis wi

73 specific chromatin profiles define adaptive genomic regions, and highlight how different epigenetic

74 ved specificity, focused testing of targeted genomic regions, and is available as an open-source R pa

75 Saccharomyces cerevisiae chromosome V, other genomic regions, and random sequences.

76 ever, methods to identify and sequence these genomic regions are currently limited.

77 Since these traits and genomic regions are distinct from those associated with

78 more, protein products mapping to non-coding genomic regions are identified; highlighting a potential

79 al supergene shows that large nonrecombining genomic regions are prone to cause multifarious effects

80 es and evolutionary divergence of these nORF genomic regions are similar and indicate a potential rol

81 Constrained genomic regions are those that have an unusually low var

82 of human chromosome 21 or orthologous mouse genomic regions, are providing valuable insights into th

83 candidate genes were identified in strong LD genomic regions around 11 genome-wide significant marker

84 Annotation of the genomic regions around peak SNPs helped to predict sever

85 al candidate genes and QTLs within strong LD genomic regions around the significant SNPs.

86 Many high-throughput methods produce sets of genomic regions as one of their main outputs.

87 rved variation in mutation susceptibility by genomic region, as well as by DNA strand.

88 e sword transcriptome and are located in the genomic region associated with this trait we identify th

89 ciation studies (GWAS) for Landrace, reveled genomic region associated with VS traits on Sus scrofa c

90 tion norm model were carried out to identify genomic regions associated with AFC in Nellore heifers,

91 work, we analyzed all mutations in candidate genomic regions associated with BDQ- and DLM-resistant p

92 To identify genomic regions associated with blast resistance against

93 array also has a high density of markers in genomic regions associated with cancer susceptibility, i

94 Similarly, multiple genomic regions associated with COPD-related phenotypes,

95 Mb of the genome that is highly enriched for genomic regions associated with heritability of neuropsy

96 o evaluate the evolutionary forces acting on genomic regions associated with human complex traits and

97 studies have been successful at identifying genomic regions associated with important traits, but ro

98 We report maize genomic regions associated with indirect defence and pro

99 and whole-genome sequencing data to discover genomic regions associated with lung function.

100 h migration, which includes the discovery of genomic regions associated with migration and molecular

101 We identified several genomic regions associated with one or more of the analy

102 sensitivity sequencing (MH-seq), to identify genomic regions associated with open chromatin in Arabid

103 osase Tn5, have been widely used to identify genomic regions associated with open chromatin.

104 cohorts were also significantly enriched in genomic regions associated with schizophrenia although n

105 association analyses have uncovered multiple genomic regions associated with T2D, but identification

106 y linked to wing-color pattern loci or other genomic regions associated with visual mate preference.

107 ere to estimate genetic parameters, identify genomic regions associated, and estimate genomic predict

108 asurements and Main Results: We discovered a genomic region at 1q32 that was significantly associated

109 We identify 49 genomic regions at a false dicovery rate (FDR) < 0.05 th

110 We describe an unbiased screen for human genomic regions at which interindividual variation in DN

111 evelop a computational algorithm to identify genomic regions at which interindividual variation in DN

112 Copy number (CN) differences in genomic regions between closely related species can unde

113 stematic analysis highlight the relevance of genomic regions beyond UBE3A as contributing factors in

114 Finally, we identified genomic regions bound by bZIPs with promotive and repres

115 fied breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk rema

116 omatin and functional importance of specific genomic regions can be integrated similarly.

117 that have been identified to date are small genomic regions comprising a few genes(2), but recent ev

118 ctors that densify chromatin determine which genomic regions condense to form peripheral heterochroma

119 This study was initiated to identify genomic regions conferring resistance to Karnal Bunt (KB

120 enome, and yet detect a number of discordant genomic regions consistent with ancient admixture.

121 d with both flowering and maturity time in a genomic region containing GmPRR3b.

122 These SNP were located in genomic regions containing a total of 68 genes.

123 rain chalk and hyperspectral variation share genomic regions containing several plausible candidate g

124 Most interestingly, genomic regions containing sMHSs are enriched with epige

125 The joint effects of common variants in genomic regions containing susceptibility loci for infla

126 Chromothripsis is characterized by localized genomic regions containing tens to thousands of rearrang

127 These allele-specific CNAs affect genomic regions containing well-known breast-cancer gene

128 H3K27me3 depletion within the Avr1b genomic region correlated with impaired Avr1b gene silen

129 To explore any given specified genomic region, corresponding to an alternative splicing

130 ased on ReVeaL's predictability of different genomic regions, dark-matter contains enough signal to s

131 Genomic regions determining sexual compatibility often d

132 ly conserved non-coding elements (CNEs) mark genomic regions devoted to cis-regulation of key develop

133 Accordingly, very few genomic regions display differences in accessibility bet

134 show that TFAP2A activates distinct sets of genomic regions during induction of the neural plate bor

135 ants using NPL, where loci localize to large genomic regions (e.g., >50 Mb), mapped regions are well

136 for genome editing of coding and non-coding genomic regions effectively.

137 nspositional insertions into piRNA clusters, genomic regions encoding the Piwi-interacting RNAs (piRN

138 thylated oncological region (THOR), a 433-bp genomic region encompassing 52 CpG sites located immedia

139 different chromosomal amplifications of the genomic region encompassing the parEC operon encoding to

140 on circular-sequencing (EmPC-seq) to discern genomic regions enriched for transcription misincorporat

141 Genomic regions enriched with MH-seq reads are referred

142 Analysis of the genomic region flanking the deletion unveiled a large in

143 ectively), which unraveled shared and unique genomic regions for AFC in Low, Medium, and High EC leve

144 Genomic regions for celiac disease (P = 0.22) and primar

145 examine the overall association of combined genomic regions for each inflammatory disease group.

146 netic contributions of functionally distinct genomic regions for five agronomic traits, i.e., yield,

147 ency that make it possible to simulate large genomic regions for many individuals sampled from large

148 /-500 kb) previously identified by GWAS, the genomic regions for ulcerative colitis, Crohn disease, a

149 ere made from ectopic expression of the core genomic region from each genotype.

150 Several of these CT loci coincided with the genomic regions from previous studies associated with ca

151 ion enrichment in both coding and non-coding genomic regions from WGS data.

152 fer the true copy number status of genes and genomic regions from whole exome sequencing data.

153 S) on the MIR-predicted milk BHB to identify genomic regions, genes and pathways potentially affectin

154 The significant genomic regions harbored key genes that might play an im

155 We detected genomic regions harboring genes associated with distinct

156 Multi-enhancer interactions formed at genomic regions harboring genes with prominent roles in

157 DNA methylation of various genomic regions has been found to be associated with gen

158 ny, potential elements contained in the Tug1 genomic region have any activity.

159 The consequences of duplication of the same genomic region have not been systematically assessed in

160 The genomic regions highlighted differences in the physiolog

161 They identified three small genomic regions highly associated with mate preference,

162 on, which also enabled the identification of genomic regions (i.e. haplotypic blocks) influencing mul

163 feature selection, we explore the important genomic regions identified by the models for predicting

164 genome-wide markers located within specific genomic regions identified using a priori analyses.

165 t from resequencing were integrated with the genomic regions identified using the chip to refine the

166 sequences derived from natively differential genomic regions, identifying E-box motifs common to epit

167 Recent progress has been made in identifying genomic regions implicated in trait evolution on a micro

168 e Linkage Group 8 previously identified as a genomic region important for phorbol ester biosynthesis.

169 We identified a deletion of a 45-kb genomic region in the most recent First Pandemic strains

170 ur phylogeny, estimated using data from 2389 genomic regions in 1940 individuals of 1283 species, rev

171 ale-specific sequences were used to identify genomic regions in both species that are believed to con

172 e greatly enhanced by catalogs of regulatory genomic regions in cell lines and primary tissues.

173 for amplification-free enrichment of target genomic regions in the range from 5 to 60 fold, and for

174 A key issue is the complexity of the genomic regions in which they lie, which, because of the

175 using computational tools, including in dark genomic regions inaccessible by short-read sequencing.

176 eas DBSs for H3K4me3 were distributed in all genomic regions including exons, introns, intergenic, TT

177 s and assessed the predictivity over several genomic regions including genic, non-dark, non-coding, n

178 dromic repeats/Cas9-mediated deletion of the genomic region, including NRL and CRX binding sites, in

179 nome-wide significant risk signals across 78 genomic regions, including 38 novel independent risk sig

180 sublineages of all coding sequences, complex genomic regions, intergenic regions, and methylation mot

181 At exceptional genomic regions, interindividual variation in DNA methyl

182 ations between phenotypes and a variant or a genomic region into a network provides a new way to inve

183 Sequencing data for all genomic regions involved in isoniazid resistance were av

184 Chinook salmon, we show that a single, small genomic region is nearly perfectly associated with spawn

185 The amount of DNA sequence variability in a genomic region is often positively correlated with its r

186 Targeted sequencing of genomic regions is a cost- and time-efficient approach f

187 sally associated with the risk of CAD within genomic regions known to be associated with CAD.

188 t of the dark genomic matter, the non-coding genomic regions lacking any functional annotation.

189 tivariate statistical analyses that identify genomic regions likely to contain causal mutations affec

190 No other genomic regions linked to sex determination were apparen

191 Targeting highly conserved genomic regions make pan-family assays robust and resili

192 Examination of genomic regions marked by differential chromatin states

193 on of iCCA, affecting primarily the bivalent genomic regions marked with both active and repressive h

194 hat were coincident with previously reported genomic regions may be important resources for pyramidin

195 These genomic regions may be important resources in soybean br

196 red of TECs to processively transcribe large genomic regions necessitates robust mechanisms to termin

197 Rearrangement of genomic regions normally having higher or lower methylat

198 = 23.29-33.69) and the NIST high confidence genomic regions (odds ratio = 0.154-0.191).

199 e variability observed in this 5' end of the genomic region of divergent HIV-1 strains strongly sugge

200 ciated winter coat color polymorphism to the genomic region of the pigmentation gene Agouti, previous

201 AC complex exhibits similar distributions in genomic regions of EBV-positive cells and is associated

202 cterization of the intergenic region between genomic regions of GATA6-AS1 and GATA6 indicated that th

203 lation of histone H3 at lysine 27 (H3K27) in genomic regions of most eukaryotes and is critical for m

204 We sequenced all exons within the QTL and genomic regions of PRiMA1, FOXN3 and CCDC88C in Dominica

205 methyltransferase EZH2 were detected in the genomic regions of the STB-specific CGB5 and CGB7 genes.

206 plotype analysis identified a ~0.85cM shared genomic region on chromosome 16q encompassing the c.191A

207 This approach identified a small genomic region on chromosome V that underlies bleomycin-

208 e study demonstrated that a 17-Mb long 129P1 genomic region on mouse chromosome 7 conferred weight re

209 For Yorkshire, genomic regions on SSC 1 (87-91 and 282-287 Mb) and 5 (6

210 reated, for example, by duplication of large genomic regions or de novo, from previously non-coding D

211 We found that in 27 out of 39 associated genomic regions our method could reduce the number of po

212 capable of analyzing common variants in most genomic regions, our findings demonstrated the limitatio

213 re remain thousands of potentially important genomic regions overlooked by short-read sequencing that

214 Whether the SNPs in different genomic regions play different roles in trait heritabili

215 we identified 61 and 163 unique mutations in genomic regions potentially involved in BDQ- and DLM-res

216 Human genomic regions predicted to form non-B-form DNA induced

217 regulate N-protein condensation while other genomic regions promote condensate dissolution, potentia

218 Here, we discuss genomic regions prone to mutation, mechanisms contributi

219 of Biomphalaria glabrata snails, we identify genomic region PTC2 which exhibits the largest known cor

220 Genomic regions recalcitrant to inbreeding were associat

221 RNA sequence and structure in specific genomic regions regulate N-protein condensation while ot

222 lygenic associations with decline, involving genomic regions related to metabolic, developmental, and

223 hological and biological systems to identify genomic regions relevant for the etiology and treatment

224 ry elements in individual species, but these genomic regions remain difficult to align across taxonom

225 ive agronomic phenotypes and more than 1,800 genomic regions representing the targets of selection du

226 nd biologically meaningful interpretation of genomic region set data.

227 ession divergence are found near to adaptive genomic regions, show signatures of natural selection ar

228 A number of genomic regions showed strong associations with the perc

229 y upregulated several hemizygous TSG in this genomic region, significantly derepressing endogenous re

230 ated that VOCs are controlled by a few major genomic regions, some of which harbor biosynthetic enzym

231 All RP17 SVs had breakpoints within a genomic region spanning YPEL2 to LINC01476.

232 ,322 protein-coding genes as well as 229,001 genomic regions spanning 72 species.

233 for domestication-related QTL and associated genomic regions, spontaneous interspecific hybridization

234 variants, most of which locate in non-coding genomic regions, still remain a challenge in genetic res

235 is highly irregular and varies in different genomic regions such as gene bodies, promoters, and acti

236 pping and the functional analysis of sizable genomic regions, such as alternative exons.

237 e annotated genes associated with identified genomic regions suggest the associations observed are di

238 licly available genomes, 4465 high diversity genomic regions suited for targeted sequencing were iden

239 nal enhancer-like regulatory activity of the genomic region surrounding rs7173049 influencing express

240 intestinal diseases, we hypothesize that the genomic regions surrounding established genome-wide asso

241 Our results support the hypothesis that genomic regions surrounding variants associated with inf

242 gulate activities of cell/condition-specific genomic regions (target loci) in comparison to control r

243 In addition, we show the loss of a genomic region that includes virulence-related genes in

244 individuals has identified many hundreds of genomic regions that are associated with psychiatric dia

245 ) is a high-throughput technique to identify genomic regions that are bound in vivo by a particular p

246 ility of optical mapping for the analysis of genomic regions that are difficult to sequence.

247 The [AT]-increase is more pronounced in genomic regions that are non-genic, pericentromeric, tra

248 ified by CRISPR/Cas9 forces integration into genomic regions that are otherwise poor targets for SB t

249 atory regions reside within "hyper-ChIPable" genomic regions that are subject to dynamic, yet nonspec

250 ng the evolutionary degeneration expected at genomic regions that cannot freely recombine.

251 chromosomal interval was used to detect the genomic regions that condition the trait of interest.

252 ce of migration all map to a small number of genomic regions that do not overlap with results from ot

253 a large portion of sequenced sRNAs come from genomic regions that encode highly conserved miRNAs, rRN

254 racterized by dispensable genes in accessory genomic regions that exceed by orders of magnitude those

255 apping, forensic applications, and detecting genomic regions that have been under recent selection.

256 l genomic introgression signals and identify genomic regions that have introgressed from indicine int

257 s for individual chromosomes and identify 23 genomic regions that have recurrently toggled between a

258 such as alpha-1 antitrypsin deficiency, many genomic regions that influence COPD susceptibility have

259 the optimal window size for identifying the genomic regions that influence meat tenderness.

260 However, there are genomic regions that remain difficult to characterize, i

261 ian randomization to systematically annotate genomic regions that show association with kidney functi

262 We identified 1,808,810 genomic regions that showed variations in CG methylation

263 Both species shared genomic regions that underwent major selective sweeps, b

264 lly associating domains involving repetitive genomic regions, thereby unlocking a previously masked p

265 onsistent, deep coverage of information rich genomic regions to characterize polyclonal Plasmodium fa

266 enesis; different mechanisms act on distinct genomic regions to drive DNA copy changes; and chromothr

267 pigenetic modifications can extend over long genomic regions to form domain-level chromatin states th

268 ly, we searched for candidate genes at these genomic regions to gain insights into potential molecula

269 ver, the relative contributions of different genomic regions to this genome divergence pattern and un

270 The genomic regions under selection between cattle breeds si

271 geny, we identified complex sets of multiple genomic regions underlying conditional essentiality.

272 Genomic regions underlying genetic variation for 14 trai

273 genomes and preferentially removed from the genomic regions underlying selective sweeps and domestic

274 We identified multiple genomic regions underlying these traits as well as a sin

275 Here, we identified the traits and genomic regions underlying variation in this expectation

276 Selection scans indicate that most genomic regions underlying weedy adaptations do not over

277 anscription factors are closely clustered in genomic regions upstream of target genes, defining cis-r

278 loci (cis-eQTL) mapping for this 2 megabase genomic region using postmortem human brain samples.

279 ChIP is used to quantify enriched genomic regions using qPCR, and more recently is combine

280 ased approach for predicting candidate genes/genomic regions utilising the knowledge of the 3D archit

281 on of RNA polymerase containing sigma(70) to genomic regions vacated by these proteins.

282 identified by both methods, but no specific genomic region was highlighted.

283 1 region and published data from three other genomic regions, we investigated the temporal evolutiona

284 Several genomic regions were associated with leaf angle within l

285 We identified which genomic regions were more or less prone to systematic bi

286 f population demography in order to identify genomic regions which do not conform to neutral expectat

287 stomatal densities in the ILs revealed four genomic regions with a consistently low trichome density

288 For a predefined set of genomic regions with AI, RECUR compares BAF values among

289 experiments and for identifying differential genomic regions with biological significance.

290 articularly for neuropsychiatric diseases in genomic regions with cell type-specific, developmentally

291 of balanced polymorphisms may have generated genomic regions with elevated divergence.

292 We find three genomic regions with elevated nucleotide diversity, tota

293 us RNA species, and associations of numerous genomic regions with nuclear lamina, nucleoli and surfac

294 gineering, the targeted replacement of mouse genomic regions with orthologous human sequences has bec

295 led to the identification of new, unexplored genomic regions with roles in trichome formation in toma

296 nbiased, genome-wide approach, we found that genomic regions with the ability to form highly stable D

297 o visualize 3D chromatin folding at targeted genomic regions with ultra-resolution (5 x 5 x 30 nm in

298 Topologically associating domains (TADs) are genomic regions with varying lengths.

299 populations exhibited distortion at only one genomic region, with some regions being repeatedly affec

300 ploration of any NCBI epigenetic data in any genomic region without need of any bioinformatics skills