ライフサイエンスコーパス: genotype and phenotype

1 by studies investigating the interaction of genotype and phenotype.

2 e of the genome and the relationship between genotype and phenotype.

3 es networks of interacting molecules between genotype and phenotype.

4 d how to understand the relationship between genotype and phenotype.

5 determine the complex relationships between genotype and phenotype.

6 ptional regulation is a crucial link between genotype and phenotype.

7 erature stress increase correlations between genotype and phenotype.

8 ders and, thus, for the relationship between genotype and phenotype.

9 can be viewed at hierarchical levels to link genotype and phenotype.

10 ered systems offer exquisite control of both genotype and phenotype.

11 stablishing a causative relationship between genotype and phenotype.

12 the environment on the relationship between genotype and phenotype.

13 his by creating hybrid rate matrices between genotype and phenotype.

14 g for redundancy and subsequent diversity in genotype and phenotype.

15 ial animal models have a corresponding human genotype and phenotype.

16 nd in investigating the relationship between genotype and phenotype.

17 or associations between evolutionary rate of genotype and phenotype.

18 led and assessed for any association between genotype and phenotype.

19 new correlations to be drawn between disease genotype and phenotype.

20 d to inflation of false associations between genotype and phenotype.

21 tics aims to understand the relation between genotype and phenotype.

22 ould result in a lack of correlation between genotype and phenotype.

23 These data demonstrate a correlation between genotype and phenotype.

24 well as in facilitating correlations between genotype and phenotype.

25 de and in establishing a correlation between genotype and phenotype.

26 ion volume and risk factors, or between apoE genotype and phenotype.

27 ins according to their BtR-4 gene disruption genotype and phenotype.

28 le to establish a strong association between genotype and phenotype.

29 istical significance of associations between genotype and phenotype.

30 in primary tumors that are heterogeneous in genotype and phenotype.

31 ith, for many, only a loose relation between genotype and phenotype.

32 l studies also evaluate the relation between genotype and phenotype.

33 athways into intermediate components between genotype and phenotype.

34 can be harnessed to span the divide between genotype and phenotype.

35 rovide insight into the relationship between genotype and phenotype.

36 data for exploring the relationship between genotype and phenotype.

37 g meaningful relationships between C. parvum genotype and phenotype.

38 of the potential relationships between human genotype and phenotype.

39 Dahl salt-resistant (R) rats ascertained for genotype and phenotype.

40 P- tumors exhibit fundamental differences in genotype and phenotype.

41 which show an excellent concordance between genotype and phenotype.

42 ing embryos) are proposed to mediate between genotype and phenotype.

43 alogue of variants to bridge the gap between genotype and phenotype.

44 chromosome A01 showed co-segregation between genotype and phenotype.

45 t for understanding the relationship between genotype and phenotype.

46 t allows multivariate representation of both genotype and phenotype.

47 approaches to study the relationship between genotype and phenotype.

48 ent methods may miss important links between genotype and phenotype.

49 hizophrenia, there is no direct link between genotype and phenotype.

50 l health care, as a possible marker for LQT1 genotype and phenotype.

51 haromyces as permanent, heritable changes in genotype and phenotype.

52 oded protein will often aid the link between genotype and phenotype.

53 or unravelling complex relationships between genotype and phenotype.

54 of 42 patients and the relationship between genotype and phenotype.

55 vocally demonstrating an association between genotype and phenotype.

56 by studies investigating the interaction of genotype and phenotype.

57 olution and whole-genome sequencing can link genotype and phenotype.

58 ental and physiological mechanisms that link genotype and phenotype.

59 only recent generations are available to be genotyped and phenotyped.

60 p of hereditary disorders with heterogeneous genotypes and phenotypes.

61 to modify the existing associations between genotypes and phenotypes.

62 GN's community annotation tools for curating genotypes and phenotypes.

63 proved clusterings that better differentiate genotypes and phenotypes.

64 d with high resolution by correlating strain genotypes and phenotypes.

65 ry serotype M3 strains representing distinct genotypes and phenotypes.

66 used in discovering the association between genotypes and phenotypes.

67 f precise information on the mapping between genotypes and phenotypes.

68 herited retinal disorders with heterogeneous genotypes and phenotypes.

69 with European ancestry from the database of genotypes and phenotypes.

70 nate tumours universally regardless of their genotypes and phenotypes.

71 ingococci were isolated and characterized by genotyping and phenotyping.

72 h high-throughput technologies for bacterial genotyping and phenotyping.

73 t to establish a causal relationship between genotype and phenotype?

74 ise linear causal relationship between tumor genotype and phenotype, a reminder of logician Carveth R

75 nsive compilations of ecologically important genotypes and phenotypes accrue, predictive abilities fo

76 stage one were gathered from the database of genotypes and phenotypes; additional control individuals

77 Studies of viral genotype and phenotype after virus rebound revealed that

78 Variant genotypes and phenotypes, allelic frequencies in differe

79 sis that provides a clear resolution of PON1 genotypes and phenotypes allowing for a reasonable asses

80 ating event, were generated and submitted to genotype and phenotype analyses.

81 step for unraveling the relationship between genotype and phenotype and can yield important insights

82 association between antimicrobial resistance genotype and phenotype and correlated phylogenetic clust

83 f the invasive and metastatic uveal melanoma genotype and phenotype and underscores the plasticity of

84 for Biotechnology Information's Database of Genotypes and Phenotypes and made available via a custom

85 tion for studies of the relationship between genotype and phenotype, and a basis for studies of the p

86 ed pathways, infer the relationships between genotype and phenotype, and explain disease heterogeneit

87 f the gene repertoire, in the way of linking genotype and phenotype, and in the selection approach.

88 Cell genotype and phenotype, and nutrient, oxygen, and growth

89 Pathogenic mutations are classified by both genotype and phenotype, and the NUMT sequences permits d

90 h susceptibility gene, relationships between genotypes and phenotypes, and potential interactions bet

91 volutionary questions, followed by sampling, genotyping, and phenotyping, and ending in analytical me

92 For discovering how genotype and phenotype are linked to each other, it is e

93 continued study of the relationships between genotype and phenotype are necessary to better understan

94 ing datasets of patients that have been both genotyped and phenotyped are the key requisite when aimi

95 Moreover, discordant results between genotypes and phenotypes are a common source of confusio

96 New genotypes and phenotypes are recognized and new therapie

97 selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleterious throug

98 copy, enabling longitudinal studies of tumor genotype and phenotype as a function of response to chem

99 refully scrutinize the relationships between genotype and phenotype as they pertain to clinical pract

100 Considering the genotype and phenotype as two complex objects, this also

101 ifications, elucidating causal links between genotype and phenotype, as well as the ability to design

102 as lasso and elastic net in inferring sparse genotype and phenotype associations, in which the number

103 o be quantitative and identified population, genotype, and phenotype associations.

104 his approach, making it difficult to connect genotype and phenotype at the level of individual cells.

105 to be able to rigorously characterize their genotypes and phenotypes at the cellular and molecular l

106 s a challenge to detect associations between genotypes and phenotypes because of insufficient sample

107 from their ability to compute a link between genotype and phenotype, but their ability to accurately

108 A new approach was developed to link genotype and phenotype by fusing the target RBP to zinc

109 enes using a novel strategy based on linking genotype and phenotype by in vitro compartmentalization

110 to explain the complex relationship between genotype and phenotype by using network models.

111 hin a biofilm population, cells with diverse genotypes and phenotypes coexist, suggesting that distin

112 Genotype and phenotype correlated between OP and BALF is

113 There was found to be evidence of genotype and phenotype correlation in Wilson disease, wh

114 HD risk factor and suggests that complex DAT genotype and phenotype correlations contribute to differ

115 an-ethnic disease variants, provided initial genotype and phenotype correlations, and established the

116 echanisms of disease and to explore personal genotype and phenotype correlations.

117 In our study, we simulated genotype and phenotype data and then compared the powers

118 ips to phenotype images, providing access to genotype and phenotype data associated with quantitative

119 To address this gap, we collected both genotype and phenotype data for 39,696 individuals with

120 or), a program to simulate region/gene-level genotype and phenotype data for complex and Mendelian tr

121 nation frequency, and the ability to collect genotype and phenotype data in community databases.

122 Including both genotype and phenotype data together with measurements o

123 Genotype and phenotype data were correlated and examined

124 To incorporate both genotype and phenotype data with gene expression, 4 grou

125 tabase driven web-based tool that integrates genotype and phenotype data, association analysis result

126 Combined with more genotype and phenotype data, they will help facilitate m

127 sentation and features from high dimensional genotype and phenotype data.

128 summary statistics without individual-level genotype and phenotype data.

129 require the availability of individual-level genotype and phenotype data.

130 plied to summary data, without access to raw genotype and phenotype data.

131 The database of Genotypes and Phenotypes (dbGaP) Data Browser was develo

132 The Database of Genotypes and Phenotypes (dbGap) is a National Institute

133 reely available through the NCBI database of Genotypes and Phenotypes (dbGaP).

134 association studies through the database of Genotypes and Phenotypes (dbGaP).

135 and Environment project [via the database of Genotypes and Phenotypes (dbGAP)].

136 e of etoposide, and the relationship between genotype and phenotype differs by race.

137 Together, the complementary routes of genotype- and phenotype-driven mutagenesis will provide

138 Two routes, genotype- and phenotype-driven, can be used for the reco

139 nges to elucidating the relationship between genotype and phenotype, especially in neopolyploid speci

140 In the gulf between genotype and phenotype exists proteins and, in particula

141 phor for describing the relationship between genotype and phenotype for a population under selection.

142 tunity to establish functional links between genotype and phenotype for complex traits such as type 1

143 ical foundations to make connections between genotype and phenotype for ecologically important pigmen

144 results demonstrate a robust correlation of genotype and phenotype for GLI3 mutations and strongly s

145 Recognition of the distinct genotype and phenotype for this subset of APAs could fac

146 Over 700 F2 mice were densely genotyped and phenotyped for a panel of 40 body and orga

147 n described, providing a wealth of different genotypes and phenotypes for genetic and other studies.

148 ctural information, as well as corresponding genotypes and phenotypes generated by a highly sensitive

149 tic models (phenotype; genotype; phenotype + genotype; and phenotype + genotype + demographic + envir

150 o obtain gene expression data in addition to genotypes and phenotypes, giving us new opportunities to

151 Understanding genome-wide links between genotype and phenotype has generally been difficult due

152 Correlation of genotype and phenotype has provided important informatio

153 enetic variation in vivo, and changes in Rev genotype and phenotype have been shown to coincide with

154 as well as more precise correlations between genotype and phenotype have facilitated the progress mad

155 nd navigation bar, (ii) expanded support for genotypes and phenotypes, (iii) comprehensive phenotype

156 Comparison between genotype and phenotype in 23 families failed to yield an

157 aim was to determine the association between genotype and phenotype in 681 affected male participants

158 light on the intricate relationship between genotype and phenotype in a wide range of inherited huma

159 precision medicine, bridging the gap between genotype and phenotype in an in vivo setting.

160 ease apart the complex relationships between genotype and phenotype in aneuploidy and segmental aneus

161 ation for exploring the relationship between genotype and phenotype in angiosperms, enhance the utili

162 r genes and provides a possible link between genotype and phenotype in cancer.

163 This study provides the first link between genotype and phenotype in choanoflagellates and raises t

164 xperiments have defined correlations between genotype and phenotype in chronic pain diseases and focu

165 y examines the relationship between the FBN1 genotype and phenotype in families with extremely mild p

166 the natural history of the relation between genotype and phenotype in hereditary hemochromatosis and

167 comprehensive genome-wide approaches to link genotype and phenotype in model organisms.

168 was identified as Flv by correlation between genotype and phenotype in nine mouse strains.

169 ur understanding of the relationship between genotype and phenotype in plants.

170 or population studies of association between genotype and phenotype in S. cerevisiae.

171 toward developing a more robust link between genotype and phenotype in this complex disorder.

172 atively straightforward relationship between genotype and phenotype in this group of the PBDs, such t

173 vel with kinase domain (KD) mutation status, genotype, and phenotype in 1855 Ph(+) leukemias.

174 approach analyses the relationships between genotypes and phenotypes in terms of differences (change

175 evidence for adaptation in vivo, in terms of genotype and phenotype including antibiotic resistance.

176 tions involve a complex relationship between genotype and phenotype, including interactions between u

177 reatment algorithms, which are based on both genotype and phenotype information.

178 Bridging genotype and phenotype is a fundamental biomedical chall

179 Understanding the relationship between genotype and phenotype is a major biological question an

180 ple mutational cause, the connection between genotype and phenotype is complex and multidimensional,

181 This inconsistency between genotype and phenotype is illustrated in the malformatio

182 Although the causal relationship between genotype and phenotype is not presently understood, our

183 COL1A1 and COL1A2, the relationship between genotype and phenotype is not yet well understood.

184 Dissecting the relationship between genotype and phenotype is one of the central goals in de

185 Mapping between genotype and phenotype is one of the primary goals of ev

186 The relationship between genotype and phenotype is remarkably close in the animal

187 However, the relationship between genotype and phenotype is very weak.

188 The Database of Genotypes and Phenotypes is a National Institutes of Hea

189 e also beginning to make connections between genotype and phenotype; it appears that certain mutation

190 plexities of the relationships between virus genotype and phenotype make such predictions extremely d

191 phenotype establishes a causal link between genotype and phenotype, making possible carrier and popu

192 ergence of artemisinin resistance-associated genotypes and phenotypes (maximum mean change in antibod

193 High-throughput mapping between genotype and phenotype may apply to artificial selection

194 icant associations between fetal heart rate, genotype, and phenotype; mean third trimester prelabor f

195 The National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE((R))) was es

196 ase, created The National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).

197 We analyzed the genotype and phenotype of CF patients 40 years and older

198 ur ability to understand the linkage between genotype and phenotype of disease.

199 Here, we report the genotype and phenotype of each affected patient, as well

200 Comparisons of the genotype and phenotype of each virus suggested that VP1/

201 ebella from adult chimeras in which both the genotype and phenotype of individual cells are marked an

202 se hepatitis virus (MHV), to investigate the genotype and phenotype of MHV quasispecies selected for

203 ng-sought odorants used to recognize the MHC genotype and phenotype of other individuals.

204 or polyploidy, has important effects on the genotype and phenotype of plants, potentially altering e

205 The genotype and phenotype of ten transformants derived from

206 The genotype and phenotype of the M2-2 deletion mutant were

207 In the present study, both the genotype and phenotype of these mice were characterized,

208 Studies of genotypes and phenotypes of FNH and HCAs have led to the

209 The type III secretion genotypes and phenotypes of isolates cultured from the p

210 Tumor subclasses differ according to the genotypes and phenotypes of malignant cells as well as t

211 Here, we report detailed genotypes and phenotypes of TALEN-edited MECP2 mutant cy

212 Analysis of the genotypes and phenotypes of these mutant genes has revea

213 were tested in the present study by further genotyping and phenotyping of 23 cpb2-positive C. perfri

214 were tested in the present study by further genotyping and phenotyping of 29 cpb2-positive C. perfri

215 Here we describe the systematic generation, genotyping and phenotyping of 711 iPS cell lines derived

216 Comparative genotyping and phenotyping of nearly 12,000 O. biennis i

217 rombocytopenia that were recruited to the UK Genotyping and Phenotyping of Platelets (GAPP) study.

218 We compared genotyping and phenotyping of the four inhibitory KIRs t

219 Recent developments allow unparalleled genotyping and phenotyping of tumours, providing a pleth

220 However, genotype and phenotype often do not correlate due to con

221 n Omnibus, Entrez Probe, GENSAT, Database of Genotype and Phenotype, Online Mendelian Inheritance in

222 XLP but that there is no correlation between genotype and phenotype or outcome.

223 These populations will be genotyped and phenotyped, permitting high-power and high

224 ts (9 LQT1, 9 LQT2, 5 LQT3, and 2 LQT5) with genotype and phenotype positive LQTS underwent ECG imagi

225 opulation-based analytical measurements with genotype and phenotype provides productive insight into

226 at globally affects the relationship between genotype and phenotype, [PSI(+)] expands the conceptual

227 y program that can efficiently generate both genotypes and phenotypes, regardless of pedigree structu

228 Understanding the relation between genotype and phenotype remains a major challenge.

229 Genotype and phenotype results were provided to patients

230 orphism is a strong and stable clustering in genotype and phenotype space.

231 Selective genotyping and phenotyping strategies are used to lower

232 We examine the efficiency of different genotyping and phenotyping strategies in inbred line cro

233 ived from two publicly available database of Genotypes and Phenotypes studies [phs000404.v1.p1 and ph

234 nd unrelated healthy subjects, by definitive genotyping and phenotyping techniques.

235 ement and decline in cost of high-throughput genotyping and phenotyping technologies, genome-wide ass

236 Both genotype and phenotype tests require interpretation, and

237 mplexity of the mapping relationship between genotype and phenotype that is a consequence of epistasi

238 sis of the evolutionary relationship between genotype and phenotype that quantitatively links point m

239 ntegrate the strength of association between genotype and phenotype, the variability in the genetic b

240 Because of its desirable genotype and phenotype, this mutant may have the potenti

241 ional prediction scores, allele frequencies, genotypes and phenotypes) to determine the optimal analy

242 alysing the pooled data comprising bacterial genotype and phenotype together with clinical metadata w

243 are to directly test the association between genotype and phenotype using a phylogenetic framework.

244 infer networks of causal relationships among genotypes and phenotypes using expression quantitative t

245 A possible relationship between genotype and phenotype (virus replication efficiency) is

246 The connection between genotype and phenotype was assessed by determining the a

247 in genomic DNA, and the concordance of TPMT genotype and phenotype was determined.

248 The relation between genotype and phenotype was examined in detail.

249 erferon action and the chromosome 21 trisomy genotype and phenotype was presented in this journal in

250 Interpretation of genotypes and phenotypes was concordant in 57 (85%) of t

251 o be the mechanism leading to the changes in genotype and phenotype we observed.

252 er for Biotechnology Information database of genotypes and phenotypes website.

253 neutropenic episodes were recorded, and MBL genotype and phenotype were determined by heteroduplex a

254 samples exhibiting discrepancies between the genotype and phenotype were found to be due to low red c

255 Although genotype and phenotype were largely concordant for first

256 Thus, the sclerotic (Os/+) or normal (+/+) genotype and phenotype were present in, and transmitted

257 Genotypes and phenotypes were correlated by determining

258 dom mating with N(e) of 50, 100, or 200, SNP genotypes and phenotypes were generated on 200, 500, or

259 uring recovery, as viruses with two distinct genotypes and phenotypes were isolated.

260 e in detail the complex relationship between genotypes and phenotypes with both theoretical and pract

261 We tested single-locus associations between genotypes and phenotypes with regression models.

262 (INS) and investigated associations between genotype and phenotype, with special attention to extra-

263 ng understanding of the relationship between genotype and phenotype, with the ability to predict some