ライフサイエンスコーパス: genotyping

1 s reporting findings that support the use of genotyping.

2 dentified 7 HPV types not included in the LA genotyping.

3 er than 1000 copies per mL were selected for genotyping.

4 luence technologies ranging from printing to genotyping.

5 83% overall type-specific concordance for LA genotyping.

6 C9orf72 repeat expansion detection; and APOE genotyping.

7 ared results with traditional microsatellite genotyping.

8 ic variation ascertained through genome-wide genotyping.

9 ovement in cost effectiveness of large-scale genotyping.

10 R-D in the same assay that is used for tumor genotyping.

11 and human papillomavirus (HPV) detection and genotyping.

12 nters for Disease Control and Prevention for genotyping.

13 re assessed by droplet digital PCR or Taqman genotyping.

14 ication and capturing the data necessary for genotyping.

15 us reinfection, and 2 were unrecoverable for genotyping.

16 6713 cases and 5964 controls with exome-wide genotyping.

17 ple of 733 patients who underwent successful genotyping, 226 (30.8%) were women and 507 (69.2%) were

18 We address this issue by genotyping 511 samples from 23 populations of Sicily, So

19 the ADO-EGR2, IRF8, and CEBPB-PTPN1 loci by genotyping 969 Iranian cases and 826 controls.

20 proach for discovering genomic variation and genotyping a cohort.

21 compression, the model can lead to improved genotyping accuracy.

22 for this association by conducting extensive genotyping across the DDC gene in a large cohort of 120

23 alling performance compared to other popular genotyping algorithms.

24 tion sequencing (NGS) approaches to parasite genotyping allow sensitive detection of minority variant

25 Plasma cfDNA genotyping also allowed for the recovery of mutations th

26 loid underwent clinical evaluation including genotyping and (99m)TC-3,3-diphosphono-1,2-propanodicarb

27 wide significance (P < 5 x 10(-8)) by direct genotyping and ADO-EGR2 by imputation.

28 Additional genotyping and association analyses in GSDs combined wit

29 Through genotyping and dense imputation mapping from whole-genom

30 nticipate that iDES will aid the noninvasive genotyping and detection of ctDNA in research and clinic

31 Parasite genotyping and drug concentrations were investigated in

32 l genomes provided additional information on genotyping and drug resistance mutations.

33 d phs000982.v1.p1] in the USA), we performed genotyping and exploited the recently established Haplot

34 High-density genotyping and imputation identified 100,000 variants w

35 Genotyping and imputation was performed in fluticasone f

36 Through replication genotyping and imputation we found that a predicted prot

37 in 35,962 independent samples using de novo genotyping and imputed genotypes.

38 Here we use genome-wide SNP genotyping and meiomapping of both polar bodies to ident

39 vels were measured from plasma, and both DNA genotyping and mRNA expression levels in peripheral bloo

40 a sequential therapeutic process comprising genotyping and mutant HTT-linkage of SNPs, followed by p

41 emission tomography, apolipoprotein E (APOE) genotyping and neuropsychological testing.

42 a novel haplotype-based method for robustly genotyping and phasing STRs from Illumina sequencing dat

43 Here we describe the systematic generation, genotyping and phenotyping of 711 iPS cell lines derived

44 Pyrosequencing genotyping and sequencing of the voltage gated sodium ch

45 Novel genotyping and sequencing technologies have led to the d

46 e a revolution, based in large part on novel genotyping and sequencing technologies.

47 e attractive for their ease of use for rapid genotyping and their codominant nature.

48 irst on single nucleotide polymorphism (SNP) genotyping and then with whole-genome data and show how

49 Genotyping and transmission chain confirmed interhuman t

50 We did variable-number-of-tandem-repeat genotyping and whole-genome sequencing of isolates.

51 of 76 Mongolian yaks using high-density SNP genotyping and whole-genome sequencing.

52 e to lack of resources needed to perform HLA genotyping and, in one country, EMA assay.

53 les for viral load quantitation, typing, and genotyping, and blood samples for transcriptome analyses

54 s a highly discriminatory assay for B. canis genotyping, and can serve as a useful molecular epidemio

55 ough a combination of direct sequencing, KIR genotyping, and data mining from the Great Ape Genome Pr

56 ing it to established methods of HLA and KIR genotyping, and determining KIR genotypes from 1000 Geno

57 on may aid point-of-care pathogen detection, genotyping, and disease monitoring.

58 combined whole-exome sequencing, array-based genotyping, and linkage analysis to identify putative pa

59 mission tomography imaging, apolipoprotein E genotyping, and neuropsychological assessment.

60 at combines Phenotype MicroArray(TM) and SSR genotyping appeared useful to assess the performance and

61 For flexibility in genotyping applications, SNPs polymorphic between tetrap

62 The aim was to adapt a genotyping approach based on SSR (Simple Sequence Repeat

63 The genotyping approach presented here can be used to interr

64 We applied this genotyping approach to field-collected parasites collect

65 Dense genotyping approaches have revealed much about the genet

66 sion settings is problematic for traditional genotyping approaches.

67 Variant discovery and genotyping are relatively straightforward tasks on a sin

68 density single nucleotide polymorphism (SNP) genotyping array (Illumina MegaEx).

69 p an 'African Diaspora Power Chip' (ADPC), a genotyping array consisting of tagging SNPs, useful in c

70 ways plagued the post-processing of Illumina genotyping array data is the strand definition.

71 or exome sequencing data", and "genome-wide genotyping array data" authors looked for information re

72 All subjects were genotyped using a custom genotyping array designed to evaluate single-nucleotide

73 We screened variants on an exome-focused genotyping array in >300,000 participants (replication i

74 nd rigorous quality control steps, using SNP genotyping array intensity data.

75 tions suggests this type of African-specific genotyping array is both necessary and valuable for faci

76 ermore, StrandScript can examine an Illumina genotyping array manifest file and can detect all proble

77 Currently, Illumina is one of the largest genotyping array manufacturers.

78 ect 90K single nucleotide polymorphism (SNP) genotyping array to identify the genetic loci for SET an

79 ce, regardless of the sequencing strategy or genotyping array used to characterize each sample.

80 uency/rare coding variant-enriched Exomechip genotyping array, we sought to identify genetic variants

81 available Illumina Infinium ShrimpLD-24 v1.0 genotyping array.

82 estry genotyped on the Illumina Multi-Ethnic Genotyping Array.

83 le cultivars using the Axiom Wheat Breeder's Genotyping Array.

84 ariation for the cost of a dense genome-wide genotyping array.

85 ) were selected to develop a large-scale SNP genotyping array.

86 riants are not well covered in most germline genotyping arrays and are understudied in relation to ep

87 Here we use human genome-wide genotyping arrays and new whole-genome HCV viral sequenc

88 introduction of high-throughput sequencing, genotyping arrays continue to be a viable source for con

89 The advent of genotyping arrays enabled large-scale genome-wide associ

90 LAMMS and other algorithms to calls from SNP genotyping arrays for a set of 3164 samples; and we use

91 all genotyping data generated from Illumina genotyping arrays to the reference forward strand.

92 of rare variants in target samples typed on genotyping arrays.

93 The CNV genotyping assay described here uses a homeologous gene

94 ea accessions supported the development of a genotyping assay for 51 128 SNPs, which was then applied

95 ase chain reaction assay (Roche Linear Array genotyping assay).

96 ate a customized high-throughput array-based genotyping assay.

97 Our methods, data and genotyping assays can be used as a resource for the mous

98 by standard population sequencing-based HIV genotyping assays.

99 pa-I and Fok-I) were identified using TaqMan genotyping assays.

100 We achieve genotyping by introducing barcoded genetic variants into

101 imeric probe DNA can be realized for the SNP genotyping by optimizing the operation condition and seq

102 Genotyping by sequencing (GBS) generates datasets that a

103 The availability of new tools such as genotyping by sequencing and bioinformatics pipelines fo

104 Genotyping by sequencing identified 14,059 segregating p

105 124 individuals and their parents using the genotyping by sequencing method.

106 n of C. annuum to generate 66,960 SNPs using genotyping by sequencing.

107 In this study genotyping-by- sequencing (GBS) was used to construct th

108 Conventional genotyping-by-sequencing (cGBS) strategies suffer from h

109 t investigation, we have explored the use of Genotyping-By-Sequencing (GBS) in Iranian cannabis.

110 A high throughput genome wide genotyping-by-sequencing (GBS) method was used to genera

111 than 50 SNP arrays and 15 different types of genotyping-by-sequencing (GBS) platforms have been devel

112 Genotyping-by-sequencing (GBS), a method to identify gen

113 We employed a modified genotyping-by-sequencing approach and generated genetic

114 In addition, we used a genotyping-by-sequencing approach to examine the genetic

115 A genotyping-by-sequencing approach was used to develop SN

116 tGBS(R) genotyping-by-sequencing is a novel method of genome red

117 ensions of Mexico were characterized through genotyping-by-sequencing technology.

118 Through genotyping-by-sequencing, 23,931 informative SNPs were s

119 nd show how rapid and accurate SNP and indel genotyping can be carried out across the genomes in the

120 Genotyping confirmed recrudescence of the initial parasi

121 ticipants with AMD worse than category 1 and genotyping data available.

122 Given genotyping data for each of eight pooled samples, demuxl

123 genetic similarities, we analysed Immunochip genotyping data from 1,434 LVV patients and 3,814 unaffe

124 oposed methodology by analyzing whole-genome genotyping data from a lung function study.

125 s of a 320 indica rice diversity panel using genotyping data from the high-density rice array.

126 We used outcome and genotyping data from the large publicly available Intern

127 op StrandScript, a tool that can convert all genotyping data generated from Illumina genotyping array

128 ified in blood and plaque from raw intensity genotyping data in men within the Athero-Express biobank

129 -week follow-up visits and for whom complete genotyping data were available.

130 and demonstrate its effectiveness using real genotyping data.

131 w major features: (i) handling of very large genotyping datasets like the ones generated by GBS; (ii)

132 Microsatellite genotyping demonstrated a common founder effect shared b

133 Genotyping demonstrated the same strain in all PCP cases

134 s in cancer and diseases through large-scale genotyping, developing methods to map rare chromatin int

135 may also detect EGFR T790M missed by tissue genotyping due to tumor heterogeneity in resistant disea

136 porates population-specific parameters and a genotyping error rate as well as provides a length-based

137 quencies and seem able to uncover additional genotyping error that would have gone unnoticed in HWE t

138 tumor-infiltrated tissue to examine whether genotyping errors substantially biased estimates of asso

139 s suffer from high rates of missing data and genotyping errors, particularly at heterozygous sites.

140 n improved read depth distribution and fewer genotyping errors.

141 Genotyping for 36 HPV genotypes was performed using the

142 The pooled sensitivity of HPV 16/18 genotyping for CIN3+ was about 70% for women with either

143 Accessible and real-time genotyping for diagnostic, prognostic, or treatment purp

144 To evaluate the accuracy of genotyping for HPV types 16 and 18 and its utility as a

145 mber 1, 2009, to May 1, 2016, underwent KASP genotyping for selected variants in NR3C1 (rs56149945, r

146 ata from existing GWAS datasets and targeted genotyping for studies that did not have GWAS data.

147 linically probable or possible DLB underwent genotyping for the 7 known AJ GBA mutations and the LRRK

148 To better define this role, we performed genotyping for the rs867186-G variant, associated with i

149 We estimated social group size by genotyping hair samples collected at 120 main setts acro

150 stry and polymerase chain reaction-based DNA genotyping have emerged as powerful diagnostic methods f

151 nment of sliding windows and can perform (i) genotyping, (ii) clustering of new genomes, (iii) detect

152 Genotyping, imputation, and genome-wide association stud

153 on criteria, we selected 24 SNPs for further genotyping in 1,516 breast cancer cases and 1,189 noncan

154 Genotyping in 3,609 T1D families showed that rs56048322

155 We performed genome-wide genotyping in 446 pediatric patients with de novo AML en

156 matory bowel disease loci using high-density genotyping in 67,852 individuals.

157 variants in endometriosis using exome-array genotyping in 7164 cases and 21005 controls, and a repli

158 ptured using exome-sequencing and exome-chip genotyping in a genetically isolated population from the

159 Replication was assessed by de novo genotyping in a panel of additional 117 cases and 380 co

160 Genotyping in an additional 10,780 never-smoking cases a

161 me sequencing (WGS) in 2,284 samples and SNP genotyping in an additional 14,904 samples.

162 Thus, we propose the inclusion of KIR genotyping in graft selection criteria for CBT.

163 By achieving high-density SNP genotyping in populations for which no reference genome

164 providing these ideal conditions for plasma genotyping in resource-constrained settings, the field h

165 GBS data usage and perform high-density SNP genotyping in the absence of a reference.

166 nd technical processes that adversely affect genotyping include copy-number-variation, paralogous seq

167 Further genotyping indicated that a single non-synonymous substi

168 t a rapid, scalable, and flexible method for genotyping individual parasites that enables molecular e

169 l equation models incorporating whole-genome genotyping information.

170 iciency virus type 1 (HIV-1) drug resistance genotyping is recommended to help in the selection of an

171 ts not otherwise identified through standard genotyping, it demonstrates no clear advantage over the

172 continued discovery efforts should focus on genotyping large numbers of surgically-confirmed endomet

173 e telomeric haplotypes; this single-telomere genotyping method may ultimately enable delineation of h

174 We used a PCR genotyping method with 380 domesticated barley landraces

175 erogroup isolates and were compared with two genotyping methods (real-time PCR [rt-PCR] and whole-gen

176 hicken and demonstrates how using predictive genotyping methods and targeted bioassays can focus toxi

177 the lack of discriminatory power of standard genotyping methods.

178 Future increases in sample size and denser genotyping might facilitate the identification of gene-g

179 enotyped F2 plants using multiplexed shotgun genotyping (MSG), and located MSG markers to the genome

180 marker, we developed a novel method for SSR genotyping, named as AmpSeq-SSR, which combines multiple

181 he performance of microfluidic SNP arrays in genotyping noninvasive samples from grey wolves, Europea

182 Based on the genotyping of 2 loss-of-function (LoF) variants c.5101C>

183 cing (WES) and canine high-density (cHD) SNP genotyping of 28 dogs from 3 breeds to compare the SNP a

184 Exome analysis and direct genotyping of 4,233 HIV-1-infected individuals reveals t

185 Genotyping of 95% of the trees at nine nuclear microsate

186 To facilitate high-throughput genotyping of Arachis species, 20 genotypes were re-sequ

187 of BKV DNA before and after transplantation; genotyping of BKV subtypes was performed.

188 In its current implementation, GTD requires genotyping of both the transplant recipient and donor.

189 Genotyping of cagA from feces of both infected and uninf

190 Here, genotyping of candidate single nucleotide polymorphisms

191 Genotyping of cell-free plasma DNA was performed by usin

192 d complicated sample preparation process for genotyping of clinical samples.

193 Using simulations, we show that bulk genotyping of data simulated under a neutral model of so

194 rovide general guidelines for successful SNP genotyping of degraded DNA using microfluidic technology

195 These results demonstrate that cfDNA genotyping of DLBCL is as accurate as genotyping of the

196 he inference decomposes into the independent genotyping of each genomic position for which a sufficie

197 nticoagulant, anticardiolipin antibodies and genotyping of factor V Leiden (FVL), factor II G20210A (

198 The more recent study with high-density genotyping of immune-related loci in individuals with As

199 netics studies typically involve genome-wide genotyping of individuals from a diverse network of ance

200 Genotyping of large populations through genome-wide asso

201 ed systemic sclerosis genetics, we performed genotyping of major histocompatibility complex-borne mic

202 STRs in parallel, and provides the accurate genotyping of microsatellites.

203 Such data allows cost-efficient genotyping of millions of single nucleotide polymorphism

204 In one study, genotyping of rs3093077 failed, and rs1800947 was typed

205 In the replication stage, we performed genotyping of significant and suggestive results from th

206 Accurate and efficient genotyping of simple sequence repeats (SSRs) constitutes

207 Genotyping of single CD34(+)CD38(-) cell-derived colonie

208 sease Cohort Study was conducted through the genotyping of single nucleotide polymorphisms (SNPs) rep

209 eq) allows for the genome-wide discovery and genotyping of single-nucleotide polymorphisms in hundred

210 New approaches that use genotyping of the AHR1 ligand binding domain to screen f

211 ere tested in parallel with conventional PCR genotyping of the capsid shell domain; 164/164 samples w

212 cfDNA genotyping of DLBCL is as accurate as genotyping of the diagnostic biopsy to detect clonally r

213 Genotyping of the groundnut 'Reference Set' containing 3

214 Recent work has leveraged the extensive genotyping of the Icelandic population to perform long-r

215 Genotyping of the rs660895 polymorphism in the HLA-DRB1

216 Genotyping of the tumors revealed that oncogenic RAS mut

217 Genotyping of the two SNPs was performed using Taqman as

218 d genome-wide single-nucleotide polymorphism genotyping on 381 individuals from 85 language groups in

219 ormed parasite transcriptional profiling and genotyping on samples from an antimalarial treatment tri

220 ry with single-nucleotide polymorphism (SNP) genotyping on the Illumina Exome Beadchip.

221 e editing with an innovative high-throughput genotyping pipeline utilizing KASP (Kompetitive Allele-S

222 e preferred sample for HIV-1 drug resistance genotyping, plasma analysis requires sophisticated labor

223 ver, cannot be achieved without an efficient genotyping platform such as SNP arrays.

224 ing ultra-high-throughput and cost-effective genotyping platforms for applied breeding programs.

225 trols in a Chinese population using Illumina genotyping platforms to identify CNVs and related genes

226 It is expected that such genotyping platforms will be achieved in the next ten ye

227 Crop breeding chips and genotyping platforms will provide unprecedented opportun

228 by building a transmission map, completed by genotyping Pneumocystis isolates and by a control of che

229 C), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941

230 After a quick review of some high-throughput genotyping protocols relevant in the context of a common

231 e they did not complete the follow-up or PCR genotyping result was not conclusive.

232 were 100% concordant with Linear Array (LA) genotyping results for 9 plasmid samples and fully or pa

233 actor dimensionality reduction revealed that genotyping results for rs11244787, rs1871054, rs243866,

234 Cytomegalovirus genotyping results from a phase 2 trial comparing brinci

235 Depending on the genotyping results, multiple strategies can be adopted t

236 a self-collected penile swab sample for HPV genotyping (Roche Linear Array) and completed a demograp

237 By additional genotyping, rs7270354 at MMP9 and rs4888383 at BCAR1 als

238 as erupted in recent years regarding whether genotyping should be part of standard care for patients

239 uijn graph, which is aimed at 'detecting and genotyping simple and complex genetic variants in an ind

240 After filtering and additional genotyping steps, we selected 28 low-frequency missense,

241 d/or allele specific sequence that allow for genotyping strategies based on binary readout of PCR pro

242 le computational method for population-level genotyping studies as well as a flexible NGS-based repla

243 We discuss the potential of genotyping studies for examining effects of noradrenergi

244 With the advent of large genotyping studies involving hundreds of thousands of in

245 Genotyping studies revealed that PMN responsiveness to P

246 Using deep sequencing and case-control genotyping studies, we show that in French Canadians, th

247 Genotyping succeeded in 79% and 58% of samples, respecti

248 However, the existing methods for SSR genotyping suffer from low sensitivity, low accuracy, lo

249 Genotyping suggests that capsular switching has occurred

250 Using genotyping techniques that have differentiated Mycobacte

251 adapt to the needs of evolving study design, genotyping technologies and user needs in the future.

252 It means that genotypic data from genotyping technologies that provide a high proportion o

253 al breeding platforms should adopt automated genotyping technologies, either array or sequencing base

254 ects traditional QTL mapping with the newest genotyping technologies.

255 Advances in genotyping technology have, over the past decade, enable

256 izing KASP (Kompetitive Allele-Specific PCR) genotyping technology to create scarless isogenic cell m

257 Furthermore, we report a DNA-based genotyping test used to demonstrate the presence of the

258 s performed using the Roche Linear Array HPV genotyping test.

259 The Validation of Human Papillomavirus (HPV) Genotyping Tests (VALGENT) studies offer an opportunity

260 e risk stratification offered by partial HPV genotyping tests also have relevance for HIV-positive wo

261 Genotyping this SNP in 1,008 breast cancer, 1,128 lung c

262 Uncoupling discovery from genotyping thus allows for the majority of this missed c

263 We aimed to use molecular genotyping to assess antimalarial drug resistance select

264 We used microsatellite genotyping to assess genetic relatedness.

265 We used qRT-PCR and genotyping to characterize residual circulating parasite

266 Genotyping to distinguish between parasite clones is now

267 from METASTROKE Consortium with genome-wide genotyping to test this hypothesis.

268 e applications of the increasingly available genotyping tools and whole-genome sequencing data, and a

269 rently, single nucleotide polymorphism (SNP) genotyping using microfluidic arrays is emerging as an e

270 Genotyping was accomplished on Infinium Human610-QUAD ve

271 TMEM106B genotyping was carried out, and years of education recor

272 HIV genotyping was done in 1589 individuals with a viral loa

273 Genotyping was done using the OncoArray.

274 Genotyping was done with a custom Illumina Omni2.5M arra

275 A new MLVA-13Bc method for B. canis genotyping was established by combining eight newly-deve

276 CHEK2*1100delC genotyping was mostly done by a custom Taqman assay.

277 In 135 patients with tTG >10xULN, HLA genotyping was performed and in all it was compatible wi

278 elf-collected penile swab specimens, and HPV genotyping was performed by polymerase chain reaction am

279 Genotyping was performed in 377 children from the at-ris

280 Genotyping was performed on a subsample of 1284 AMD case

281 Sequence-based genotyping was performed on antigen-positive samples.

282 Genotyping was performed using microarrays, followed by

283 Genotyping was performed using the major adhesion protei

284 f reactivity, 95% PPV or challenge, and IL13 genotyping was performed.

285 years, brain magnetic resonance imaging and genotyping was performed.

286 UL56 genotyping was successful for 12 of 15 patients.

287 Genotyping was successful for 90% of the sample.

288 tly experienced relapse, confirmed by strain genotyping, was compared to that in samples from patient

289 Using viral genotyping, we estimated the prevalence of HSV-2 dual-st

290 Combining multiple approaches for genotyping, we found that outcrossing populations on ave

291 METHODS AND Using array-based and targeted genotyping, we found that rs80356779, a p.Pro479Leu vari

292 Using whole-exome sequencing followed by genotyping, we have identified a low-frequency coding va

293 nce data and polymerase chain reaction-based genotyping, we identified nonsynonymous single-nucleotid

294 Through DNA genotyping, we tested 54,003 coding-sequence variants co

295 Blood samples for DNA genotyping were collected from all participants.

296 ciency of the chimeric probe DNA for the SNP genotyping were verified by using the SPRi sensor under

297 ned previously using sequences of the 739-nt genotyping window.

298 urther propose a strategy for integrating IG genotyping with functional Ab profiling data as a means

299 Patient-specific TP53 genotyping with functional evaluation of p53 protein may

300 We analyzed patterns of genomic variation by genotyping, with the Ovine SNP50K microarray, 394 indivi