ライフサイエンスコーパス: glipizide

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1 seen with the sulfonylureas tolbutamide and glipizide.

2 ) insulin three to four times daily, with no glipizide.

3 long-acting insulin; 2) addition of daytime glipizide; 3) insulin twice daily, with no glipizide; an

4 The sulfonylurea glipizide (50 microM) produced a transient 25% increase

5 Using the TRAMP transgenic mouse model, glipizide, a widely used drug for type 2 diabetes mellit

6 glyburide (aHR, 1.26 [CI, 1.16 to 1.37]) and glipizide (aHR, 1.15 [CI, 1.06 to 1.26]) in subgroups by

7 effects of the water-soluble sodium salt of glipizide, an inhibitor of ATP-sensitive potassium chann

8 e glipizide; 3) insulin twice daily, with no glipizide; and 4) insulin three to four times daily, wit

9 diet and titration with either 5 to 20 mg of glipizide gastrointestinal therapeutic system (GITS) (n

10 jects were randomly assigned to glyburide or glipizide gastrointestinal therapeutic system (GITS).

11 creased in the glyburide group compared with glipizide GITS in the 20-mg study (P=.05).

12 Favorable health economic outcomes for glipizide GITS included higher retained employment (97%

13 , 5.8 mmol/L [105 mg/dL] for a 20-mg dose of glipizide GITS vs 8.7 mmol/L [157 mg/dL] for placebo), a

14 lucose levels decreased with active therapy (glipizide GITS) vs placebo (7.5% 0.1% vs 9.3%+/-0.1% and

15 ken together, these results demonstrate that glipizide has the potential to be repurposed as an effec

16 t by N(omega)-nitro-L-arginine methyl ester, glipizide, indomethacin or 17-octadecynoic acid.

17 Moreover, glipizide inhibits the tubular structure formation of hu

18 domly assigned to groups treated with either glipizide or insulin at doses appropriate to control hyp

19 Intriguingly, glipizide significantly reduces microvessel density in P

20 However, the higher doses of glipizide sodium salt attenuated the increments in plasm

21 renteral administration of the water-soluble glipizide sodium salt attenuates vascular and end-organ

22 subjected to pressure-controlled hemorrhage, glipizide sodium salt improved mean arterial pressure in

23 ntramuscular (10 and 40 mg/kg) injections of glipizide sodium salt or vehicle.

24 In addition, the glipizide treated cats had threefold higher basal and fi

25 At the end of the study all 4 glipizide-treated cats had islet amyloid deposits, where

26 nt 6-month combination therapy of metformin, glipizide XL, and acarbose to lower A1C to 6.7% and 2-da

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