ライフサイエンスコーパス: globose

1 tages along the progression from multipotent globose basal cell (GBC) progenitor to differentiated ol

2 NEUROD1-expressing cells are found among the globose basal cell population: they are actively prolife

3 l indicates that most ckPCs reside among the globose basal cell populations and act downstream of hor

4 rs using the monoclonal antibody GBC-2 (GBC, globose basal cell) and fluorescence activated cell sort

5 typically similar to the OSN progenitor, the globose basal cell.

6 Globose basal cells (GBCs) act as the active stem cell p

7 least two populations of presumed stem cells-globose basal cells (GBCs) and horizontal basal cells (H

8 d categories: clones that invariably contain globose basal cells (GBCs) and/or neurons, clones that a

9 In the olfactory neuroepithelium, globose basal cells (GBCs) are considered to be the dire

10 ells (HBCs) and some among the population of globose basal cells (GBCs) are stem cells, but the two t

11 l, as both horizontal basal cells (HBCs) and globose basal cells (GBCs) have features in common with

12 tion of a cell surface antigen, expressed on globose basal cells (GBCs) of the rodent olfactory epith

13 ated expression of LIFR also was detected on globose basal cells (GBCs), a subpopulation of which are

14 In contrast, globose basal cells (GBCs, marked by staining with GBC-2

15 rast, Hes5 is expressed by a small subset of globose basal cells and by olfactory ensheathing glia in

16 ons of basal stem cells, frequently dividing globose basal cells and quiescent horizontal basal cells

17 Most of the Sox2/Pax6-positive globose basal cells are actively cycling, but some expre

18 As a consequence, NEUROD1-expressing globose basal cells are best classified as immediate neu

19 All of the persisting globose basal cells are marked by SOX2 expression, sugge

20 GFP-labeled cells include both proliferative globose basal cells as well as immature OSNs exhibiting

21 expression of Hes1 marks that population of globose basal cells committed to making sustentacular ce

22 Neither supporting nor globose basal cells contained WGA-HRP, suggesting that u

23 Transplanted globose basal cells engraft and, in aggregate, give rise

24 ive neuropotency, which is characteristic of globose basal cells in the normal olfactory epithelium,

25 large fraction of residual, marker-confirmed globose basal cells initiate expression of Hes1.

26 ment of Sox2 and Pax6 to these categories of globose basal cells is confirmed by a temporal analysis

27 nsory neurons derive from NeuroD1-expressing globose basal cells of the immediate neuronal precursor

28 ive 5-HT3a mRNA and GFP are expressed within globose basal cells of the olfactory and vomeronasal epi

29 ent OE, there are horizontal basal cells and globose basal cells that are morphologically and functio

30 Globose basal cells were purified from other potential p

31 ontaining thymidine labelling appeared to be globose basal cells, although supporting cells also occa

32 The differentiation of globose basal cells, another multipotent progenitor popu

33 vidual clones, derived from single engrafted globose basal cells, can consist of a mixture of neurons

34 ells engraft and, in aggregate, give rise to globose basal cells, neurons, sustentacular cells, and s

35 Among globose basal cells, Sox2 and Pax6 are co-expressed by p

36 romide activates a population of multipotent globose basal cells, which reconstitute all depleted cel

37 and held in reserve, and mitotically active globose basal cells.

38 ular cells, horizontal basal cells, and some globose basal cells.

39 s having round cell bodies similar to rodent globose basal cells.

40 irms the reciprocity between gland cells and globose basal cells.

41 and increased turnover of their precursors, globose basal cells.

42 oscleromorphs, with hexactine spicules and a globose body form inherited from reticulosan ancestors.

43 proliferative cells within the population of globose (light) basal cells (GBCs) give rise to new neur

44 es, multinucleated giant cells, and numerous globose or subglobose, lemon-shaped cells producing mult

45 and later), TuJ1-positive cells acquire the globose shape of mature hair cells.